-
1
-
-
84890946148
-
Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease
-
de Zeeuw, D., Akizawa, T., Audhya, P., Bakris, G. L., Chin, M., Christ-Schmidt, H., Goldsberry, A., Houser, M., Krauth, M., Lambers Heerspink, H. J. et al. (2013) Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease. N. Engl. J. Med. 369, 2492-2503
-
(2013)
N. Engl. J. Med
, vol.369
, pp. 2492-2503
-
-
De Zeeuw, D.1
Akizawa, T.2
Audhya, P.3
Bakris, G.L.4
Chin, M.5
Christ-Schmidt, H.6
Goldsberry, A.7
Houser, M.8
Krauth, M.9
Lambers Heerspink, H.J.10
-
2
-
-
21044436751
-
NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy
-
Satoh, M., Fujimoto, S., Haruna, Y., Arakawa, S., Horike, H., Komai, N., Sasaki, T., Tsujioka, K., Makino, H. and Kashihara, N. (2005) NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy. Am. J. Physiol. Renal Physiol. 288, F1144-F1152
-
(2005)
Am. J. Physiol. Renal Physiol.
, vol.288
-
-
Satoh, M.1
Fujimoto, S.2
Haruna, Y.3
Arakawa, S.4
Horike, H.5
Komai, N.6
Sasaki, T.7
Tsujioka, K.8
Makino, H.9
Kashihara, N.10
-
3
-
-
84868628539
-
eNOS deficiency predisposes podocytes to injury in diabetes
-
Yuen, D. A., Stead, B. E., Zhang, Y., White, K. E., Kabir, M. G., Thai, K., Advani, S. L., Connelly, K. A., Takano, T., Zhu, L. et al. (2012) eNOS deficiency predisposes podocytes to injury in diabetes. J. Am. Soc. Nephrol. 23, 1810-1823
-
(2012)
J. Am. Soc. Nephrol.
, vol.23
, pp. 1810-1823
-
-
Yuen, D.A.1
Stead, B.E.2
Zhang, Y.3
White, K.E.4
Kabir, M.G.5
Thai, K.6
Advani, S.L.7
Connelly, K.A.8
Takano, T.9
Zhu, L.10
-
4
-
-
0034625532
-
Folic acid reverts dysfunction of endothelial nitric oxide synthase
-
Stroes, E. S., van Faassen, E. E., Yo, M., Martasek, P., Boer, P., Govers, R. and Rabelink, T. J. (2000) Folic acid reverts dysfunction of endothelial nitric oxide synthase. Circ. Res. 86, 1129-1134
-
(2000)
Circ. Res.
, vol.86
, pp. 1129-1134
-
-
Stroes, E.S.1
van Faassen, E.E.2
Yo, M.3
Martasek, P.4
Boer, P.5
Govers, R.6
Rabelink, T.J.7
-
5
-
-
70350610765
-
Mechanistic insights into folic acid-dependent vascular protection: dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: a novel HPLC-based fluorescent assay for DHFR activity
-
Gao, L., Chalupsky, K., Stefani, E. and Cai, H. (2009) Mechanistic insights into folic acid-dependent vascular protection: dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: a novel HPLC-based fluorescent assay for DHFR activity. J. Mol. Cell. Cardiol. 47, 752-760
-
(2009)
J. Mol. Cell. Cardiol.
, vol.47
, pp. 752-760
-
-
Gao, L.1
Chalupsky, K.2
Stefani, E.3
Cai, H.4
-
6
-
-
84869220435
-
Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice
-
Cheng, H., Wang, H., Fan, X., Paueksakon, P. and Harris, R. C. (2012) Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Kidney Int. 82, 1176-1183
-
(2012)
Kidney Int
, vol.82
, pp. 1176-1183
-
-
Cheng, H.1
Wang, H.2
Fan, X.3
Paueksakon, P.4
Harris, R.C.5
-
7
-
-
5444235606
-
Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes
-
Delles, C., Schneider, M. P., Oehmer, S., Fleischmann, I., Fleischmann, E. F. and Schmieder, R. E. (2004) Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes. Nephrol. Dial. Transplant. 19, 2513-2518
-
(2004)
Nephrol. Dial. Transplant.
, vol.19
, pp. 2513-2518
-
-
Delles, C.1
Schneider, M.P.2
Oehmer, S.3
Fleischmann, I.4
Fleischmann, E.F.5
Schmieder, R.E.6
-
8
-
-
58249108732
-
Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus
-
Ritt, M., Ott, C., Raff, U., Schneider, M. P., Schuster, I., Hilgers, K. F., Schlaich, M. P. and Schmieder, R. E. (2009) Renal vascular endothelial function in hypertensive patients with type 2 diabetes mellitus. Am. J. Kidney Dis. 53, 281-289
-
(2009)
Am. J. Kidney Dis.
, vol.53
, pp. 281-289
-
-
Ritt, M.1
Ott, C.2
Raff, U.3
Schneider, M.P.4
Schuster, I.5
Hilgers, K.F.6
Schlaich, M.P.7
Schmieder, R.E.8
-
9
-
-
34249869003
-
Impact of telmisartan versus ramipril on renal endothelial function in patients with hypertension and type 2 diabetes
-
Schmieder, R. E., Delles, C., Mimran, A., Fauvel, J. P. and Ruilope, L. M. (2007) Impact of telmisartan versus ramipril on renal endothelial function in patients with hypertension and type 2 diabetes. Diabetes Care 30, 1351-1356
-
(2007)
Diabetes Care
, vol.30
, pp. 1351-1356
-
-
Schmieder, R.E.1
Delles, C.2
Mimran, A.3
Fauvel, J.P.4
Ruilope, L.M.5
-
10
-
-
33748434597
-
Impaired basal NO activity in patients with glomerular disease and the influence of oxidative stress
-
Schaufele, T. G., Schlaich, M. P., Delles, C., Klingbeil, A. U., Fleischmann, E. H. and Schmieder, R. E. (2006) Impaired basal NO activity in patients with glomerular disease and the influence of oxidative stress. Kidney Int. 70, 1177-1181
-
(2006)
Kidney Int
, vol.70
, pp. 1177-1181
-
-
Schaufele, T.G.1
Schlaich, M.P.2
Delles, C.3
Klingbeil, A.U.4
Fleischmann, E.H.5
Schmieder, R.E.6
-
11
-
-
79551582074
-
Reduction in basal nitric oxide activity causes albuminuria
-
Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P. and Schmieder, R. E. (2011) Reduction in basal nitric oxide activity causes albuminuria. Diabetes 60, 572-576
-
(2011)
Diabetes
, vol.60
, pp. 572-576
-
-
Ott, C.1
Schneider, M.P.2
Delles, C.3
Schlaich, M.P.4
Schmieder, R.E.5
-
12
-
-
11144356870
-
Folic acid improves endothelial function in children and adolescents with type 1 diabetes
-
Pena, A. S., Wiltshire, E., Gent, R., Hirte, C. and Couper, J. (2004) Folic acid improves endothelial function in children and adolescents with type 1 diabetes. J. Pediatr. 144, 500-504
-
(2004)
J. Pediatr.
, vol.144
, pp. 500-504
-
-
Pena, A.S.1
Wiltshire, E.2
Gent, R.3
Hirte, C.4
Couper, J.5
-
13
-
-
0036153005
-
Assessment of endothelial function of the renal vasculature in human subjects
-
Delles, C., Jacobi, J., Schlaich, M. P., John, S. and Schmieder, R. E. (2002) Assessment of endothelial function of the renal vasculature in human subjects. Am. J. Hypertens. 15, 3-9
-
(2002)
Am. J. Hypertens.
, vol.15
, pp. 3-9
-
-
Delles, C.1
Jacobi, J.2
Schlaich, M.P.3
John, S.4
Schmieder, R.E.5
-
14
-
-
84891851622
-
Poor glycemic control is related to increased nitric oxide activity within the renal circulation of patients with type 2 diabetes
-
Schneider, M. P., Ott, C., Schmidt, S., Kistner, I., Friedrich, S. and Schmieder, R. E. (2013) Poor glycemic control is related to increased nitric oxide activity within the renal circulation of patients with type 2 diabetes. Diabetes Care 36, 4071-4075
-
(2013)
Diabetes Care
, vol.36
, pp. 4071-4075
-
-
Schneider, M.P.1
Ott, C.2
Schmidt, S.3
Kistner, I.4
Friedrich, S.5
Schmieder, R.E.6
-
15
-
-
79955463009
-
Folic acid treatment normalizes NOS-dependence of vascular tone in the metabolic syndrome
-
Schneider, M. P., Schlaich, M. P., Harazny, J. M., Raff, U., Ritt, M., Ott, C. and Schmieder, R. E. (2011) Folic acid treatment normalizes NOS-dependence of vascular tone in the metabolic syndrome. Obesity 19, 960-967
-
(2011)
Obesity
, vol.19
, pp. 960-967
-
-
Schneider, M.P.1
Schlaich, M.P.2
Harazny, J.M.3
Raff, U.4
Ritt, M.5
Ott, C.6
Schmieder, R.E.7
-
16
-
-
0042669988
-
L-arginine-induced vasodilation of the renal vasculature is not altered in hypertensive patients with type 2 diabetes
-
Delles, C., Schneider, M. P., Oehmer, S., Fleischmann, E. H. and Schmieder, R. E. (2003) L-arginine-induced vasodilation of the renal vasculature is not altered in hypertensive patients with type 2 diabetes. Diabetes Care 26, 1836-1840
-
(2003)
Diabetes Care
, vol.26
, pp. 1836-1840
-
-
Delles, C.1
Schneider, M.P.2
Oehmer, S.3
Fleischmann, E.H.4
Schmieder, R.E.5
-
17
-
-
0042164620
-
Vitamin C augments the renal response to L-arginine in smokers
-
Schneider, M. P., Klingbeil, A. U., Delles, C., Schmidt, B. M., John, S. and Schmieder, R. E. (2003) Vitamin C augments the renal response to L-arginine in smokers. Nephrol. Dial. Transplant. 18, 1512-1517
-
(2003)
Nephrol. Dial. Transplant.
, vol.18
, pp. 1512-1517
-
-
Schneider, M.P.1
Klingbeil, A.U.2
Delles, C.3
Schmidt, B.M.4
John, S.5
Schmieder, R.E.6
-
18
-
-
0001459424
-
The renal clearances of substituted hippuric acid derivatives and other aromatic acids in dog and man
-
Smith, H. W., Finkelstein, N., Aliminosa, L., Crawford, B. and Graber, M. (1945) The renal clearances of substituted hippuric acid derivatives and other aromatic acids in dog and man. J. Clin. Invest. 24, 388-404
-
(1945)
J. Clin. Invest.
, vol.24
, pp. 388-404
-
-
Smith, H.W.1
Finkelstein, N.2
Aliminosa, L.3
Crawford, B.4
Graber, M.5
-
19
-
-
84866134987
-
The p47phox- and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes
-
Youn, J. Y., Gao, L. and Cai, H. (2012) The p47phox- and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes. Diabetologia 55, 2069-2079
-
(2012)
Diabetologia
, vol.55
, pp. 2069-2079
-
-
Youn, J.Y.1
Gao, L.2
Cai, H.3
-
20
-
-
78649913769
-
Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy
-
Sedeek, M., Callera, G., Montezano, A., Gutsol, A., Heitz, F., Szyndralewiez, C., Page, P., Kennedy, C. R., Burns, K. D., Touyz, R. M. and Hebert, R. L. (2010) Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy. Am. J. Physiol. Renal Physiol. 299, F1348-F1358
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
-
-
Sedeek, M.1
Callera, G.2
Montezano, A.3
Gutsol, A.4
Heitz, F.5
Szyndralewiez, C.6
Page, P.7
Kennedy, C.R.8
Burns, K.D.9
Touyz, R.M.10
Hebert, R.L.11
-
21
-
-
84876569255
-
Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction
-
Sukumar, P., Viswambharan, H., Imrie, H., Cubbon, R. M., Yuldasheva, N., Gage, M., Galloway, S., Skromna, A., Kandavelu, P., Santos, C. X. et al. (2013) Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction. Diabetes 62, 2130-2134
-
(2013)
Diabetes
, vol.62
, pp. 2130-2134
-
-
Sukumar, P.1
Viswambharan, H.2
Imrie, H.3
Cubbon, R.M.4
Yuldasheva, N.5
Gage, M.6
Galloway, S.7
Skromna, A.8
Kandavelu, P.9
Santos, C.X.10
-
22
-
-
24944458112
-
Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation
-
Cai, S., Khoo, J., Mussa, S., Alp, N. J. and Channon, K. M. (2005) Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation. Diabetologia 48, 1933-1940
-
(2005)
Diabetologia
, vol.48
, pp. 1933-1940
-
-
Cai, S.1
Khoo, J.2
Mussa, S.3
Alp, N.J.4
Channon, K.M.5
-
23
-
-
84885407597
-
Folic acid modulates eNOS activity via effects on posttranslational modifications and protein-protein interactions
-
Taylor, S. Y., Dixon, H. M., Yoganayagam, S., Price, N. and Lang, D. (2013) Folic acid modulates eNOS activity via effects on posttranslational modifications and protein-protein interactions. Eur. J. Pharmacol. 714, 193-201
-
(2013)
Eur. J. Pharmacol.
, vol.714
, pp. 193-201
-
-
Taylor, S.Y.1
Dixon, H.M.2
Yoganayagam, S.3
Price, N.4
Lang, D.5
-
24
-
-
78651345743
-
Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney
-
Hwang, S. Y., Siow, Y. L., Au-Yeung, K. K., House, J. and O, K. (2011) Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney. Am. J. Physiol. Renal. Physiol. 300, F189-F198
-
(2011)
Am. J. Physiol. Renal. Physiol.
, vol.300
-
-
Hwang, S.Y.1
Siow, Y.L.2
Au-Yeung, K.K.3
House, J.O.K.4
-
25
-
-
79960017540
-
Effect of chronic kidney disease on the expression of thiamin and folic acid transporters
-
Bukhari, F. J., Moradi, H., Gollapudi, P., Ju Kim, H., Vaziri, N. D. and Said, H. M. (2011) Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. Nephrol. Dial. Transplant. 26, 2137-2144
-
(2011)
Nephrol. Dial. Transplant.
, vol.26
, pp. 2137-2144
-
-
Bukhari, F.J.1
Moradi, H.2
Gollapudi, P.3
Ju Kim, H.4
Vaziri, N.D.5
Said, H.M.6
-
26
-
-
77951645401
-
Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial
-
House, A. A., Eliasziw, M., Cattran, D. C., Churchill, D. N., Oliver, M. J., Fine, A., Dresser, G. K. and Spence, J. D. (2010) Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial. JAMA 303, 1603-1609
-
(2010)
JAMA
, vol.303
, pp. 1603-1609
-
-
House, A.A.1
Eliasziw, M.2
Cattran, D.C.3
Churchill, D.N.4
Oliver, M.J.5
Fine, A.6
Dresser, G.K.7
Spence, J.D.8
-
27
-
-
84863211300
-
The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis
-
Jardine, M. J., Kang, A., Zoungas, S., Navaneethan, S. D., Ninomiya, T., Nigwekar, S. U., Gallagher, M. P., Cass, A., Strippoli, G. and Perkovic, V. (2012) The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis. BMJ 344, e3533
-
(2012)
BMJ
, vol.344
-
-
Jardine, M.J.1
Kang, A.2
Zoungas, S.3
Navaneethan, S.D.4
Ninomiya, T.5
Nigwekar, S.U.6
Gallagher, M.P.7
Cass, A.8
Strippoli, G.9
Perkovic, V.10
-
28
-
-
84871819023
-
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of type 2 diabetes
-
Sedeek, M., Gutsol, A., Montezano, A. C., Burger, D., Nguyen Dinh Cat, A., Kennedy, C. R., Burns, K. D., Cooper, M. E., Jandeleit-Dahm, K., Page, P. et al. (2013) Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of type 2 diabetes. Clin. Sci. 124, 191-202
-
(2013)
Clin. Sci.
, vol.124
, pp. 191-202
-
-
Sedeek, M.1
Gutsol, A.2
Montezano, A.C.3
Burger, D.4
Nguyen Dinh Cat, A.5
Kennedy, C.R.6
Burns, K.D.7
Cooper, M.E.8
Jandeleit-Dahm, K.9
Page, P.10
-
29
-
-
84901835198
-
Genetic targeting or pharmacologic inhibition of NADPH Oxidase Nox4 provides renoprotection in long-term diabetic nephropathy
-
Jha, J. C., Gray, S. P., Barit, D., Okabe, J., El-Osta, A., Namikoshi, T., Thallas-Bonke, V., Wingler, K., Szyndralewiez, C., Heitz, F. et al. (2014) Genetic targeting or pharmacologic inhibition of NADPH Oxidase Nox4 provides renoprotection in long-term diabetic nephropathy. J. Am. Soc. Nephrol. 25, 1237-1254
-
(2014)
J. Am. Soc. Nephrol
, vol.25
, pp. 1237-1254
-
-
Jha, J.C.1
Gray, S.P.2
Barit, D.3
Okabe, J.4
El-Osta, A.5
Namikoshi, T.6
Thallas-Bonke, V.7
Wingler, K.8
Szyndralewiez, C.9
Heitz, F.10
|