Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the camp signaling pathway and ameliorates vascular inflammation in obese diabetic mice

Journal of Nutrition

Volumn 142, Issue 4, 2012, Pages 724-730

  Babu, Pon Velayutham Anandh ^a   Si, Hongwei ^a,b   Fu, Zhuo ^a   Zhen, Wei ^a   Liu, Dongmin ^a  

^a Virginia Tech ^*  (United States)

^b TENNESSEE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CELL ADHESION MOLECULE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GENISTEIN; GLUCOSE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; VASCULAR CELL ADHESION MOLECULE 1; CYTOKINE; ENZYME INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTERY ENDOTHELIUM; ARTICLE; CELL ADHESION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; DIET SUPPLEMENTATION; DIET THERAPY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MALE; MONOCYTE; MOUSE; NONHUMAN; OBESITY; SIGNAL TRANSDUCTION; TREATMENT DURATION; VASCULITIS; ANIMAL; BLOOD; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; SECOND MESSENGER; SECRETION; VASCULAR ENDOTHELIUM;

MUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AORTA; CELL ADHESION; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOKINES; DIABETES MELLITUS, TYPE 2; DIETARY SUPPLEMENTS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GENISTEIN; HUMANS; HYPERGLYCEMIA; MALE; MICE; MICE, OBESE; MONOCYTES; OBESITY; SECOND MESSENGER SYSTEMS; VASCULITIS;

EID: 84861149561     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.152322     Document Type: Article

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