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Volumn 2, Issue 4, 2011, Pages 262-270

High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt

Author keywords

Akt; Endothelial progenitor cells; Vascular endothelial growth factor

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CD34 ANTIGEN; CD45 ANTIGEN; PROTEIN KINASE B; VASCULOTROPIN;

EID: 84890623266     PISSN: 20401116     EISSN: 20401124     Source Type: Journal    
DOI: 10.1111/j.2040-1124.2010.00093.x     Document Type: Article
Times cited : (21)

References (30)
  • 1
    • 70349387993 scopus 로고    scopus 로고
    • Effects of insulin resistance on endothelial progenitor cells and vascular repair
    • Cubbon RM, Kahn MB, Wheatcroft SB. Effects of insulin resistance on endothelial progenitor cells and vascular repair. Clin Sci (Lond) 2009; 117: 173-190.
    • (2009) Clin Sci (Lond) , vol.117 , pp. 173-190
    • Cubbon, R.M.1    Kahn, M.B.2    Wheatcroft, S.B.3
  • 2
    • 0037469204 scopus 로고    scopus 로고
    • Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemia
    • Kawamoto A, Tkebuchava T, Yamaguchi J, et al. Intramyocardial transplantation of autologous endothelial progenitor cells for therapeutic neovascularization of myocardial ischemia. Circulation 2003; 107: 461-468.
    • (2003) Circulation , vol.107 , pp. 461-468
    • Kawamoto, A.1    Tkebuchava, T.2    Yamaguchi, J.3
  • 3
    • 0035199236 scopus 로고    scopus 로고
    • Therapeutic vasculogenesis using human cord blood-derived endothelial progenitors
    • Murohara T. Therapeutic vasculogenesis using human cord blood-derived endothelial progenitors. Trends Cardiovasc Med 2001; 11: 303-307.
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 303-307
    • Murohara, T.1
  • 4
    • 73149090351 scopus 로고    scopus 로고
    • Intramuscular transplantation of G-CSF-mobilized CD34(+) cells in patients with critical limb ischemia: A phase I/IIa, multicenter, singleblinded, dose-escalation clinical trial
    • Kawamoto A, Katayama M, Handa N, et al. Intramuscular transplantation of G-CSF-mobilized CD34(+) cells in patients with critical limb ischemia: A phase I/IIa, multicenter, singleblinded, dose-escalation clinical trial. Stem Cells 2009; 27: 2857-2864.
    • (2009) Stem Cells , vol.27 , pp. 2857-2864
    • Kawamoto, A.1    Katayama, M.2    Handa, N.3
  • 5
    • 68049147002 scopus 로고    scopus 로고
    • Endothelial progenitor cells and cardiovascular cell-based therapies
    • Mund JA, Ingram DA, Yoder MC, et al. Endothelial progenitor cells and cardiovascular cell-based therapies. Cytotherapy 2009; 11: 103-113.
    • (2009) Cytotherapy , vol.11 , pp. 103-113
    • Mund, J.A.1    Ingram, D.A.2    Yoder, M.C.3
  • 6
    • 0037434561 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells, vascular function, and cardiovascular risk
    • Hill JM, Zalos G, Halcox JPJ, et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003; 348: 593-600.
    • (2003) N Engl J Med , vol.348 , pp. 593-600
    • Hill, J.M.1    Zalos, G.2    Halcox, J.P.J.3
  • 7
    • 17644433975 scopus 로고    scopus 로고
    • Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease
    • Vasa M, Fichtlscherer S, Aicher A, et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001; 89: E1-E7.
    • (2001) Circ Res , vol.89
    • Vasa, M.1    Fichtlscherer, S.2    Aicher, A.3
  • 8
    • 33747431983 scopus 로고    scopus 로고
    • Circulating progenitor cells are reduced in patients with severe lung disease
    • Fadini GP, Schiavon M, Cantini M, et al. Circulating progenitor cells are reduced in patients with severe lung disease. Stem Cells 2006; 24: 1806-1813.
    • (2006) Stem Cells , vol.24 , pp. 1806-1813
    • Fadini, G.P.1    Schiavon, M.2    Cantini, M.3
  • 9
    • 0037771087 scopus 로고    scopus 로고
    • Endothelial progenitor cells are decreased in blood of cardiac allograft patients with vasculopathy and endothelial cells of noncardiac origin are enriched in transplant atherosclerosis
    • Simper D, Wang S, Deb A, et al. Endothelial progenitor cells are decreased in blood of cardiac allograft patients with vasculopathy and endothelial cells of noncardiac origin are enriched in transplant atherosclerosis. Circulation 2003; 108: 143-149.
    • (2003) Circulation , vol.108 , pp. 143-149
    • Simper, D.1    Wang, S.2    Deb, A.3
  • 10
    • 9144271032 scopus 로고    scopus 로고
    • Endothelial progenitor cell dysfunction: A novel concept in the pathogenesis of vascular complications of type 1 diabetes
    • Loomans CJ, de Koning EJ, Staal FJ, et al. Endothelial progenitor cell dysfunction: A novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes 2004; 53: 195-199.
    • (2004) Diabetes , vol.53 , pp. 195-199
    • Loomans, C.J.1    de Koning, E.J.2    Staal, F.J.3
  • 11
    • 0037180517 scopus 로고    scopus 로고
    • Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures
    • Tepper OM, Galiano RD, Capla JM, et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002; 106: 2781-2786.
    • (2002) Circulation , vol.106 , pp. 2781-2786
    • Tepper, O.M.1    Galiano, R.D.2    Capla, J.M.3
  • 12
    • 17744388581 scopus 로고    scopus 로고
    • Risk factors for coronary artery disease, circulating endothelial progenitor cells, and the role of HMGCoA reductase inhibitors
    • Urbich C, Dimmeler S. Risk factors for coronary artery disease, circulating endothelial progenitor cells, and the role of HMGCoA reductase inhibitors. Kidney Int 2005; 67: 1672-1676.
    • (2005) Kidney Int , vol.67 , pp. 1672-1676
    • Urbich, C.1    Dimmeler, S.2
  • 13
    • 77954959369 scopus 로고    scopus 로고
    • Impaired function of circulating CD34(+) CD45(-) cells in patients with proliferative diabetic retinopathy
    • Tan K, Lessieur E, Cutler A, et al. Impaired function of circulating CD34(+) CD45(-) cells in patients with proliferative diabetic retinopathy. Exp Eye Res 2010; 91: 229-237.
    • (2010) Exp Eye Res , vol.91 , pp. 229-237
    • Tan, K.1    Lessieur, E.2    Cutler, A.3
  • 14
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S, et al. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 1999; 13: 9-22.
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3
  • 15
    • 0033529618 scopus 로고    scopus 로고
    • Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization
    • Asahara T, Masuda H, Takahashi T, et al. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res 1999; 85: 221-228.
    • (1999) Circ Res , vol.85 , pp. 221-228
    • Asahara, T.1    Masuda, H.2    Takahashi, T.3
  • 16
    • 0037065852 scopus 로고    scopus 로고
    • Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration
    • Iwaguro H, Yamaguchi J, Kalka C, et al. Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. Circulation 2002; 105: 732-738.
    • (2002) Circulation , vol.105 , pp. 732-738
    • Iwaguro, H.1    Yamaguchi, J.2    Kalka, C.3
  • 17
    • 23644446866 scopus 로고    scopus 로고
    • Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis
    • Ackah E, Yu J, Zoellner S, et al. Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. J Clin Invest 2005; 115: 2119-2127.
    • (2005) J Clin Invest , vol.115 , pp. 2119-2127
    • Ackah, E.1    Yu, J.2    Zoellner, S.3
  • 18
    • 20044366933 scopus 로고    scopus 로고
    • Therapeutic neovascularization using cord blood-derived endothelial progenitor cells for diabetic neuropathy
    • Naruse K, Hamada Y, Nakashima E, et al. Therapeutic neovascularization using cord blood-derived endothelial progenitor cells for diabetic neuropathy. Diabetes 2005; 54: 1823-1828.
    • (2005) Diabetes , vol.54 , pp. 1823-1828
    • Naruse, K.1    Hamada, Y.2    Nakashima, E.3
  • 19
    • 3943059538 scopus 로고    scopus 로고
    • Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers
    • Kondo T, Hayashi M, Takeshita K, et al. Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers. Arterioscler Thromb Vasc Biol 2004; 24: 1442-1447.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1442-1447
    • Kondo, T.1    Hayashi, M.2    Takeshita, K.3
  • 20
    • 0037055666 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial
    • Tateishi-Yuyama E, Matsubara H, Murohara T, et al. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet 2002; 360: 427-435.
    • (2002) Lancet , vol.360 , pp. 427-435
    • Tateishi-Yuyama, E.1    Matsubara, H.2    Murohara, T.3
  • 21
    • 33846565985 scopus 로고    scopus 로고
    • Safety and efficacy of autologous progenitor cell transplantation for therapeutic angiogenesis in patients with critical limb ischemia
    • Kajiguchi M, Kondo T, Izawa H, et al. Safety and efficacy of autologous progenitor cell transplantation for therapeutic angiogenesis in patients with critical limb ischemia. Circ J 2007; 71: 196-201.
    • (2007) Circ J , vol.71 , pp. 196-201
    • Kajiguchi, M.1    Kondo, T.2    Izawa, H.3
  • 22
    • 24344442873 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells and cardiovascular outcomes
    • Werner N, Kosiol S, Schiegl T, et al. Circulating endothelial progenitor cells and cardiovascular outcomes. N Engl J Med 2005; 353: 999-1007.
    • (2005) N Engl J Med , vol.353 , pp. 999-1007
    • Werner, N.1    Kosiol, S.2    Schiegl, T.3
  • 23
    • 1842507654 scopus 로고    scopus 로고
    • Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease
    • Heeschen C, Lehmann R, Honold J, et al. Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease. Circulation 2004; 109: 1615-1622.
    • (2004) Circulation , vol.109 , pp. 1615-1622
    • Heeschen, C.1    Lehmann, R.2    Honold, J.3
  • 24
    • 0028803509 scopus 로고
    • Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
    • Alon T, Hemo I, Itin A, et al. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nat Med 1995; 1: 1024-1028.
    • (1995) Nat Med , vol.1 , pp. 1024-1028
    • Alon, T.1    Hemo, I.2    Itin, A.3
  • 25
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3¢-kinase/Akt signal transduction pathway Requirement for Flk-1/KDR activation
    • Gerber HP, McMurtrey A, Kowalski J, et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3¢-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 1998; 273: 30336-30343.
    • (1998) J Biol Chem , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3
  • 26
    • 33644781862 scopus 로고    scopus 로고
    • Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance
    • Naruse K, Rask-Madsen C, Takahara N, et al. Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance. Diabetes 2006; 55: 691-698.
    • (2006) Diabetes , vol.55 , pp. 691-698
    • Naruse, K.1    Rask-Madsen, C.2    Takahara, N.3
  • 27
    • 5644271454 scopus 로고    scopus 로고
    • p38 MAPK mediates gammairradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway
    • Kumar P, Miller AI, Polverini PJ. p38 MAPK mediates gammairradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway. J Biol Chem 2004; 279: 43352-43360.
    • (2004) J Biol Chem , vol.279 , pp. 43352-43360
    • Kumar, P.1    Miller, A.I.2    Polverini, P.J.3
  • 28
    • 70350528625 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice
    • Park CW, Kim HW, Lim JH, et al. Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice. Diabetes 2009; 58: 2666-2676.
    • (2009) Diabetes , vol.58 , pp. 2666-2676
    • Park, C.W.1    Kim, H.W.2    Lim, J.H.3
  • 29
    • 33644623600 scopus 로고    scopus 로고
    • Synergistic effect of combined intramyocardial CD34+ cells and VEGF2 gene therapy after MI
    • Shintani S, Kusano K, Ii M, et al. Synergistic effect of combined intramyocardial CD34+ cells and VEGF2 gene therapy after MI. Nat Clin Pract Cardiovasc Med 2006; 3(Suppl 1): S123-S128.
    • (2006) Nat Clin Pract Cardiovasc Med , vol.3 , Issue.SUPPL 1
    • Shintani, S.1    Kusano, K.2    Ii, M.3
  • 30
    • 77956321953 scopus 로고    scopus 로고
    • Effects of diabetes mellitus on VEGF-induced proliferation response in bone marrow derived endothelial progenitor cells
    • Mieno S, Boodhwani M, Robich MP, et al. Effects of diabetes mellitus on VEGF-induced proliferation response in bone marrow derived endothelial progenitor cells. J Card Surg 2010; 25: 618-625.
    • (2010) J Card Surg , vol.25 , pp. 618-625
    • Mieno, S.1    Boodhwani, M.2    Robich, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.