Ascorbic acid prevents oxidant-induced increases in endothelial permeability

BioFactors

Volumn 37, Issue 1, 2011, Pages 46-50

  May, James M ^a   Qu, Zhi Chao ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Buthionine sulfoximine; Endothelial barrier permeability; H2O2; Menadione; Oxidative stress; Paracellular transport

Indexed keywords

ASCORBIC ACID; BUTHIONINE SULFOXIMINE; DEHYDROASCORBIC ACID; DITHIOTHREITOL; GLUTATHIONE; HYDROGEN PEROXIDE; INULIN; MALONALDEHYDE; MENADIONE; TEMPOL;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL MEMBRANE PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ANTIOXIDANTS; ASCORBIC ACID; BUTHIONINE SULFOXIMINE; CELL LINE; ENDOTHELIAL CELLS; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; INULIN; OXIDANTS; PERMEABILITY; VITAMIN K 3;

EID: 79951659977     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.134     Document Type: Article

References (23)

1. Ross, R. ( 1999) Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340, 115-126.
2. Steinberg, D., Parthasarathy, S., Carew, T. E., Khoo, J. C., and Witztum, J. L. ( 1989) Modifications of low-density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320, 915-924.
3. Cross, C. E., Van der Vliet, A., and Eiserich, J. P. ( 1998) Cigarette smokers and oxidant stress: a continuing mystery. Am. J. Clin. Nutr. 67, 184-185.
4. Baynes, J. W. ( 1991) Role of oxidative stress in development of complications of diabetes. Diabetes 40, 405-412.
5. Ceriello, A. ( 2000) Oxidative stress and glycemic regulation. Metabolism 49, 27-29.
6. Plante, G. E., Alfred, J., and Chakir, M. ( 1999) The blood vessel, linchpin of diabetic lesions. Metabolism 48, 406-409.
7. Holman, R. G. and Maier, R. V. ( 1990) Oxidant-induced endothelial leak correlates with decreased cellular energy levels. Am. Rev. Respir. Dis. 141, 134-140.
8. 2-induced increase in endothelial permeability. Am. J. Physiol. 270, L973-L978.
9. Lee, H. S., Namkoong, K., Kim, D. H., Kim, K. J., Cheong, Y. H., Kim, S. S., Lee, W. B., and Kim, K. Y. ( 2004) Hydrogen peroxide-induced alterations of tight junction proteins in bovine brain microvascular endothelial cells. Microvasc. Res. 68, 231-238.
10. McAmis, W. C., Schaeffer, R. C. Jr., Baynes, J. W., and Wolf, M. B. ( 2003) Menadione causes endothelial barrier failure by a direct effect on intracellular thiols, independent of reactive oxidant production. Biochim. Biophys. Acta Mol. Cell. Res. 1641, 43-53.
11. Lum, H. and Roebuck, K. A. ( 2001) Oxidant stress and endothelial cell dysfunction. Am. J. Physiol. Cell. Physiol. 280, C719-C741.
12. Shasby, D. M., Lind, S. E., Shasby, S. S., Goldsmith, J. C., and Hunninghake, G. W. ( 1985) Reversible oxidant-induced increases in albumin transfer across cultured endothelium: alterations in cell shape and calcium homeostasis. Blood 65, 605-614.
13. May, J. M., Qu, Z. C., and Qiao, H. ( 2009) Transfer of ascorbic acid across the vascular endothelium: mechanism and self-regulation. Am. J. Physiol. Cell Physiol. 297, C169-C178.
14. Siflinger-Birnboim, A., del Vecchio, P. J., Cooper, J. A., Blumenstock, F. A., Shepard, J. M., and Malik, A. B. ( 1987) Molecular sieving characteristics of the cultured endothelial monolayer. J. Cell. Physiol. 132, 111-117.
15. Utoguchi, N., Ikeda, K., Saeki, K., Oka, N., Mizuguchi, H., Kubo, K., Nakagawa, S., and Mayumi, T. ( 1995) Ascorbic acid stimulates barrier function of cultured endothelial cell monolayer. J. Cell. Physiol. 163, 393-399.
16. May, J. M., Qu, Z.-C., and Mendiratta, S. ( 1998) Protection and recycling of α-tocopherol in human erythrocytes by intracellular ascorbic acid. Arch. Biochem. Biophys. 349, 281-289.
17. Hissin, P. J. and Hilf, R. ( 1976) A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 74, 214-226.
18. Jones, W., Li, X., Perriott, L. M., Whitesell, R. R., and May, J. M. ( 2002) Uptake, recycling, and antioxidant functions of α-lipoic acid in endothelial cells. Free Radic. Biol. Med. 33, 83-93.
19. Harrison, F. E., Hosseini, A. H., Dawes, S. M., Weaver, S., and May, J. M. ( 2009) Ascorbic acid attenuates scopolamine-induced spatial learning deficits in the water maze. Behav. Brain Res. 205, 550-558.
20. May, J. M. and Asard, H. ( 2004) Ascorbate recycling. In Vitamin C Functions and Biochemistry in Animals and Plants ( Asard, H., May, J. M., and Smirnoff N., eds.). pp. 139-158, Bios Scientific Publishers, London.
21. Hui, Y. Y., McAmis, W. C., Baynes, J. W., Schaeffer, R. C. Jr., and Wolf, M. B. ( 2001) Effect of advanced glycation end products on oxidative stress in endothelial cells in culture: a warning on the use of cells studied in serum-free media. Diabetologia 44, 1310-1317.
22. Smith, A. R., Visioli, F., and Hagen, T. M. ( 2002) Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid. FASEB J. 16, 1102-1104.
23. Meister, A. ( 1991) Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol. Ther. 51, 155-194.