-
1
-
-
0021258643
-
Correlation between muscle glycogen synthase activity and in vivo insulin action in man
-
Bogardus, C., Lillioja, S., Stone, K., and Mott, D. 1984. Correlation between muscle glycogen synthase activity and in vivo insulin action in man. J. Clin. Invest. 73:1185-1190.
-
(1984)
J. Clin. Invest.
, vol.73
, pp. 1185-1190
-
-
Bogardus, C.1
Lillioja, S.2
Stone, K.3
Mott, D.4
-
2
-
-
0026654879
-
Intracellular defects in glucose metabolism in obese patients with noninsulin-dependent diabetes mellitus
-
Kelley, D.E., Mokan, M., and Mandarino, L. 1992. Intracellular defects in glucose metabolism in obese patients with noninsulin-dependent diabetes mellitus. Diabetes. 41:698-706.
-
(1992)
Diabetes
, vol.41
, pp. 698-706
-
-
Kelley, D.E.1
Mokan, M.2
Mandarino, L.3
-
3
-
-
0029896797
-
Roles of glucose transport and glucose phosphorylation in muscle insulin resistance of NIDDM
-
Bonadonna, R.C., et al. 1996. Roles of glucose transport and glucose phosphorylation in muscle insulin resistance of NIDDM. Diabetes. 45:915-925.
-
(1996)
Diabetes
, vol.45
, pp. 915-925
-
-
Bonadonna, R.C.1
-
4
-
-
0031938843
-
Insulin-induced hexokinase II expression is reduced in obesity and NIDDM
-
Pendergrass, M., et al. 1998. Insulin-induced hexokinase II expression is reduced in obesity and NIDDM. Diabetes. 47:387-394.
-
(1998)
Diabetes
, vol.47
, pp. 387-394
-
-
Pendergrass, M.1
-
5
-
-
0023508465
-
Effect of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase and glycogen synthase
-
Mandarino, L.J., et al. 1987. Effect of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase and glycogen synthase. J. Clin. Invest. 80:655-663.
-
(1987)
J. Clin. Invest.
, vol.80
, pp. 655-663
-
-
Mandarino, L.J.1
-
6
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 s6 kinase, DNA synthesis and glucose transporter translocation
-
Cheatham, B., et al. 1994. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis and glucose transporter translocation. Mol. Cell. Biol. 14:4902-4911.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
-
7
-
-
0029924465
-
Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin
-
Dorrestijn, J., Ouwens, D.M., Van den Berghe, N., Bos, J.L., and Matassen, J.A. 1996. Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin. Diabetologia. 39:558-563.
-
(1996)
Diabetologia
, vol.39
, pp. 558-563
-
-
Dorrestijn, J.1
Ouwens, D.M.2
Van Den Berghe, N.3
Bos, J.L.4
Matassen, J.A.5
-
8
-
-
0027249346
-
Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI 3-kinase
-
Kanai, F., et al. 1993. Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI 3-kinase. Biochem. Biophys. Res. Commun. 195:762-768.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.195
, pp. 762-768
-
-
Kanai, F.1
-
9
-
-
0029131895
-
Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin
-
Lazar, D., et al. 1995. Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin. J. Biol. Chem. 270:20801-20807.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20801-20807
-
-
Lazar, D.1
-
10
-
-
0024407053
-
Insulin receptor function and glycogen synthase activity in skeletal muscle biopsies from patients with non-insulin dependent diabetes mellitus: Effects of physical training
-
Bak, J., Jacobsen, U., Jorgensen, F., and Pedersen, O. 1989. Insulin receptor function and glycogen synthase activity in skeletal muscle biopsies from patients with non-insulin dependent diabetes mellitus: effects of physical training. J. Clin. Endocrinol. Metab. 69:158-164.
-
(1989)
J. Clin. Endocrinol. Metab.
, vol.69
, pp. 158-164
-
-
Bak, J.1
Jacobsen, U.2
Jorgensen, F.3
Pedersen, O.4
-
11
-
-
0031057526
-
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation
-
Bjornholm, N., Kawano, Y., Lehtihet, M., and Zierath, J.R. 1997. Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetis. 46:524-527.
-
(1997)
Diabetis
, vol.46
, pp. 524-527
-
-
Bjornholm, N.1
Kawano, Y.2
Lehtihet, M.3
Zierath, J.R.4
-
12
-
-
0030801342
-
Insulin activation of phosphatidylinositol 3-kinase in human skeletal muscle in vivo
-
Hickey, M.S., et al. 1997. Insulin activation of phosphatidylinositol 3-kinase in human skeletal muscle in vivo. J. Appl. Physiol. 83:718-722.
-
(1997)
J. Appl. Physiol.
, vol.83
, pp. 718-722
-
-
Hickey, M.S.1
-
13
-
-
0025832095
-
Impaired autophosphorylation of insulin receptors from abdominal skeletal muscles in nonobese subjects with NIDDM
-
Maegawa, H., Shigeta, Y., Egawa, K., and Kobayashi, M. 1991. Impaired autophosphorylation of insulin receptors from abdominal skeletal muscles in nonobese subjects with NIDDM Diabetis. 40:815-819.
-
(1991)
Diabetis
, vol.40
, pp. 815-819
-
-
Maegawa, H.1
Shigeta, Y.2
Egawa, K.3
Kobayashi, M.4
-
14
-
-
0025302645
-
Insulin-sensitive tyrosine kinase relationship within vivo insulin action in humans
-
Nyomba, B.L., Ossowski, V.M., Bogardus, C.,and Mottr, D.M. 1990. Insulin-sensitive tyrosine kinase relationship within vivo insulin action in humans. Am. J. Physiol. 258:E964-E974.
-
(1990)
Am. J. Physiol.
, vol.258
-
-
Nyomba, B.L.1
Ossowski, V.M.2
Bogardus, C.3
Mottr, D.M.4
-
16
-
-
18344412992
-
Evidence against protein kinase B as a mediator of contraction-induced glucose transport and GLUT4 translocation in rat skeletal muscle
-
Lund, S., et al. 1998. Evidence against protein kinase B as a mediator of contraction-induced glucose transport and GLUT4 translocation in rat skeletal muscle. FEBS Lett. 425:472-474.
-
(1998)
FEBS Lett.
, vol.425
, pp. 472-474
-
-
Lund, S.1
-
17
-
-
0028287972
-
Exercise induces rapid increases in GLUT4 expression, glucose transport capacity, and insulin stimulated glycogen storage in muscle
-
Ren, J., et al. 1994. Exercise induces rapid increases in GLUT4 expression, glucose transport capacity, and insulin stimulated glycogen storage in muscle. J. Biol. Chem. 269:14396-14401.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 14396-14401
-
-
Ren, J.1
-
18
-
-
0031910662
-
Regulation of hexokinase II activity and expression in human muscle by moderate exercise
-
Koval, J.A., et al. 1998. Regulation of hexokinase II activity and expression in human muscle by moderate exercise. Am. J. Physiol. 274:E304-E308.
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Koval, J.A.1
-
19
-
-
0028278938
-
Rat skeletal muscle hexokinase II mRNA and activity are increased by a single bout of acute exercise
-
O'Doherty, R., Bracy, D., Osawa, H., Wasserman, D., and Granner, D. 1994. Rat skeletal muscle hexokinase II mRNA and activity are increased by a single bout of acute exercise. Am. J. Physiol. 266:E171-E178.
-
(1994)
Am. J. Physiol.
, vol.266
-
-
O'Doherty, R.1
Bracy, D.2
Osawa, H.3
Wasserman, D.4
Granner, D.5
-
20
-
-
0021268588
-
Studies on the mechanism of improved glucose control during regular exercise in Type 2 (non-insulin-dependent) diabetes
-
Schneider, S.H., Amorosa, L.F., Khachadurian, A.K., and Ruderman, N.B. 1984. Studies on the mechanism of improved glucose control during regular exercise in Type 2 (non-insulin-dependent) diabetes. Diabetologia. 26:355-360.
-
(1984)
Diabetologia
, vol.26
, pp. 355-360
-
-
Schneider, S.H.1
Amorosa, L.F.2
Khachadurian, A.K.3
Ruderman, N.B.4
-
21
-
-
0018768939
-
The effect of physical training on glucose tolerance and plasma lipids in maturity-onset diabetes
-
Ruderman, N.B., Ganda, O.P., and Johansen, K. 1979. The effect of physical training on glucose tolerance and plasma lipids in maturity-onset diabetes. Diabetes. 28(Suppl.):89-92.
-
(1979)
Diabetes
, vol.28
, Issue.SUPPL.
, pp. 89-92
-
-
Ruderman, N.B.1
Ganda, O.P.2
Johansen, K.3
-
22
-
-
0346065774
-
Effect of physical exercise on insulin sensitivity and responsiveness in humans
-
Mikines, K.J., Sonne, B., Farrell, P.A., Tronier, B., and Galbo, H. 1988. Effect of physical exercise on insulin sensitivity and responsiveness in humans. Am. J. Physiol. 254:E248-E259.
-
(1988)
Am. J. Physiol.
, vol.254
-
-
Mikines, K.J.1
Sonne, B.2
Farrell, P.A.3
Tronier, B.4
Galbo, H.5
-
23
-
-
0029849462
-
Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin resistant subjects
-
Perseghin, G., et al. 1996. Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin resistant subjects. N. Engl. J. Med. 335:1357-1362.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1357-1362
-
-
Perseghin, G.1
-
24
-
-
0032510947
-
Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle
-
Brozinick, J.T., and Birnbaum, M.J. 1998. Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle. J. Biol. Chem. 273:14679-14682.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14679-14682
-
-
Brozinick, J.T.1
Birnbaum, M.J.2
-
25
-
-
0029008770
-
Effects of contractile activity on tyrosine phosphoproteins and P13-kinase activity in rat skeletal muscle
-
Goodyear, L., Giorgino, F., Balon, T., Condorelli, G., and Smith, R. 1995. Effects of contractile activity on tyrosine phosphoproteins and P13-kinase activity in rat skeletal muscle. Am. J. Physiol. 268:E987-E995.
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Goodyear, L.1
Giorgino, F.2
Balon, T.3
Condorelli, G.4
Smith, R.5
-
26
-
-
0028903232
-
Insulin receptor phosphorylation, insulin recepfor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects
-
Goodyear, L.J., et al. 1995. Insulin receptor phosphorylation, insulin recepfor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J. Clin. Invest. 95:2195-2204.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 2195-2204
-
-
Goodyear, L.J.1
-
27
-
-
0033010155
-
Differential effects of moderate exercise and physiological hyperinsulinemia on phosphorylation and activity of insulin signaling proteins in vivo in human skeletal muscle
-
Koval, J., et al. 1999. Differential effects of moderate exercise and physiological hyperinsulinemia on phosphorylation and activity of insulin signaling proteins in vivo in human skeletal muscle. Med. Sci. Sports Exerc. 31:998-1004.
-
(1999)
Med. Sci. Sports Exerc.
, vol.31
, pp. 998-1004
-
-
Koval, J.1
-
28
-
-
0022969898
-
Glycogen depletion and increased insulin sensitivity and responsiveness in muscle after exercise
-
Zorzano, A., Balon, T.W., Goodman, M.N., and Ruderman, N.B. 1986. Glycogen depletion and increased insulin sensitivity and responsiveness in muscle after exercise. Am. J. Physiol. 251:E664-E669.
-
(1986)
Am. J. Physiol.
, vol.251
-
-
Zorzano, A.1
Balon, T.W.2
Goodman, M.N.3
Ruderman, N.B.4
-
29
-
-
0023579696
-
Enhanced peripheral and splanchnic insulin sensitivity in NIDDM men after a single bout of exercise
-
Devlin, J., Hirschman, M., Horton, E.D., and Horton, E.S. 1986 Enhanced peripheral and splanchnic insulin sensitivity in NIDDM men after a single bout of exercise. Diabetes. 36:434-439.
-
(1986)
Diabetes
, vol.36
, pp. 434-439
-
-
Devlin, J.1
Hirschman, M.2
Horton, E.D.3
Horton, E.S.4
-
30
-
-
77049274176
-
Measurement of size and turnover rate of body glucose pool by the isotope dilution method
-
Steele, R., Wall, J., DeBodo, R., and Altszuler, N. 1956. Measurement of size and turnover rate of body glucose pool by the isotope dilution method. Am. J. Physiol. 187:15-24.
-
(1956)
Am. J. Physiol.
, vol.187
, pp. 15-24
-
-
Steele, R.1
Wall, J.2
DeBodo, R.3
Altszuler, N.4
-
31
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O.H., Rosebrough, N.J., Fan, A.L., and Randall, R.J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Fan, A.L.3
Randall, R.J.4
-
32
-
-
0025064397
-
Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor kinase
-
Endemann, G., Yonezawa, K., and Roth, R. 1990. Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor kinase. J. Biol. Chem. 265:369-400.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 369-400
-
-
Endemann, G.1
Yonezawa, K.2
Roth, R.3
-
33
-
-
0029147851
-
Immune complex kinase assays for mitogen-activated protein kinase and MEK
-
Reuter, C.W., Catling, A.D., and Weber, M.J. 1995. Immune complex kinase assays for mitogen-activated protein kinase and MEK. Methods Enzymol. 255:245-256.
-
(1995)
Methods Enzymol.
, vol.255
, pp. 245-256
-
-
Reuter, C.W.1
Catling, A.D.2
Weber, M.J.3
-
34
-
-
0031000841
-
Exercise stimulates the mitogen-activated protein kinase pathway in human skeletal muscle
-
Aronson, D., et al. 1997. Exercise stimulates the mitogen-activated protein kinase pathway in human skeletal muscle. J. Clin. Invest. 99:1251-1257.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1251-1257
-
-
Aronson, D.1
-
35
-
-
0028810236
-
4PS/IRS-2 is the alternative substrate of the insulin receptor in IRS-1 deficient mice
-
Patti, M.E., et al. 1995. 4PS/IRS-2 is the alternative substrate of the insulin receptor in IRS-1 deficient mice. J. Biol. Chem. 270:24670-24673.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24670-24673
-
-
Patti, M.E.1
-
36
-
-
0025799454
-
Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin resistant humans
-
McGuire, M.C., et al. 1991. Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin resistant humans. Diabetes. 40:939-942.
-
(1991)
Diabetes
, vol.40
, pp. 939-942
-
-
McGuire, M.C.1
-
37
-
-
0029760349
-
Altered basal and insulin-stiniulated phosphotyrosine phosphatase (PTPase) activity in skeletal muscle from NIDDM patients compared with control subjects
-
Worm, D., et al. 1996. Altered basal and insulin-stiniulated phosphotyrosine phosphatase (PTPase) activity in skeletal muscle from NIDDM patients compared with control subjects. Diabetologia. 29:1208-1214.
-
(1996)
Diabetologia
, vol.29
, pp. 1208-1214
-
-
Worm, D.1
-
38
-
-
0028032895
-
Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene
-
Araki, E., et al. 1994. Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene. Nature. 372:186-190.
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
-
39
-
-
0030890580
-
Insulin receptor substrate(IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus
-
Rondinone, C.M., et al. 1997. Insulin receptor substrate(IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus. Proc. Natl. Acad. Sci. USA. 94:4171-4175.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4171-4175
-
-
Rondinone, C.M.1
-
40
-
-
0032719024
-
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
-
Jiang, Z.Y., et al. 1999. Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J. Clin. Invest. 104:447-457.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 447-457
-
-
Jiang, Z.Y.1
-
41
-
-
0028341446
-
She is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation
-
Sasaoka, T. Draznin, B., Leitner, J.W., Langlois, W.J., and Olefsky, J.M. 1994. She is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. J. Biol. Chem. 269:10734-10738.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10734-10738
-
-
Sasaoka, T.1
Draznin, B.2
Leitner, J.W.3
Langlois, W.J.4
Olefsky, J.M.5
-
42
-
-
0031465447
-
Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase
-
De Fea, K., and Roth, R.A. 1997. Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase. J. Biol. Chem. 272:51400-31406.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 51400-131406
-
-
De Fea, K.1
Roth, R.A.2
-
43
-
-
0029119085
-
Excessive insulin receptor phosphorylation in cultured fibroblasts and in skeletal muscle
-
Dunaif, A., Xia, J., Book, C.-B.,Schenker, E., and Tang, Z. 1995. Excessive insulin receptor phosphorylation in cultured fibroblasts and in skeletal muscle. J. Clin. Invest. 96:801-810.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 801-810
-
-
Dunaif, A.1
Xia, J.2
Book, C.-B.3
Schenker, E.4
Tang, Z.5
-
44
-
-
0018485897
-
Glycogen synthase activation in human skeletal muscle: Effects of diet and exercise
-
Kochan, R.G., et al. 1979. Glycogen synthase activation in human skeletal muscle: effects of diet and exercise. Am. J. Physiol. 236:E660-E666.
-
(1979)
Am. J. Physiol.
, vol.236
-
-
Kochan, R.G.1
-
45
-
-
0030984321
-
New insights into the role and mechanism of glycogen synthase activation by insulin
-
Lawrence, J.C., and Roach, P.J. 1997. New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes. 46:541-547.
-
(1997)
Diabetes
, vol.46
, pp. 541-547
-
-
Lawrence, J.C.1
Roach, P.J.2
-
46
-
-
0026611962
-
31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate: Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation in non-insulin-dependent diabetes mellitus
-
31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate: evidence for reduced insulin-dependent muscle glucose transport or phosphorylation in non-insulin-dependent diabetes mellitus. J. Clin. Invest. 89:1069-1075.
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 1069-1075
-
-
Rothman, D.1
Shulman, R.2
Shulman, G.3
-
47
-
-
0030718605
-
Insulin signaling in human skeletal muscle. Time course and effect of exercise
-
Wojtaszewski, J.F.P., Hansen, B.F., Kiens, B., and Richter, E.A. 1997. Insulin signaling in human skeletal muscle. Time course and effect of exercise. Diabetes. 46:1775-1781.
-
(1997)
Diabetes
, vol.46
, pp. 1775-1781
-
-
Wojtaszewski, J.F.P.1
Hansen, B.F.2
Kiens, B.3
Richter, E.A.4
|