-
1
-
-
84878333056
-
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
-
Abisambra, J.F., Jinwal, U.K., Blair, L.J., O׳Leary, J.C. 3rd, Li, Q., Brady, S., Wang, L., Guidi, C.E., Zhang, B., Nordhues, B.A., Cockman, M., Suntharalingham, A., Li, P., Jin, Y., Atkins, C.A., Dickey, C.A., Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation. J. Neurosci. 33 (2013), 9498–9507.
-
(2013)
J. Neurosci.
, vol.33
, pp. 9498-9507
-
-
Abisambra, J.F.1
Jinwal, U.K.2
Blair, L.J.3
O׳Leary, J.C.4
Li, Q.5
Brady, S.6
Wang, L.7
Guidi, C.E.8
Zhang, B.9
Nordhues, B.A.10
Cockman, M.11
Suntharalingham, A.12
Li, P.13
Jin, Y.14
Atkins, C.A.15
Dickey, C.A.16
-
2
-
-
59149097747
-
Survival from hypoxia in C. elegans by inactivation of aminoacyl-tRNA synthetases
-
Anderson, L.L., Mao, X., Scott, B.A., Crowder, C.M., Survival from hypoxia in C. elegans by inactivation of aminoacyl-tRNA synthetases. Science 323 (2009), 630–633.
-
(2009)
Science
, vol.323
, pp. 630-633
-
-
Anderson, L.L.1
Mao, X.2
Scott, B.A.3
Crowder, C.M.4
-
3
-
-
84857213897
-
Misfolded PrP and a novel mechanism of proteasome inhibition
-
Andre, R., Tabrizi, S.J., Misfolded PrP and a novel mechanism of proteasome inhibition. Prion 6 (2012), 32–36.
-
(2012)
Prion
, vol.6
, pp. 32-36
-
-
Andre, R.1
Tabrizi, S.J.2
-
4
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate, M., Mitra, S., Schweitzer, E.S., Segal, M.R., Finkbeiner, S., Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 431 (2004), 805–810.
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
5
-
-
84866556522
-
Protein aggregates in Huntington׳s disease
-
Arrasate, M., Finkbeiner, S., Protein aggregates in Huntington׳s disease. Exp. Neurol. 238 (2012), 1–11.
-
(2012)
Exp. Neurol.
, vol.238
, pp. 1-11
-
-
Arrasate, M.1
Finkbeiner, S.2
-
6
-
-
77957288028
-
Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma
-
Auf, G., Jabouille, A., Guerit, S., Pineau, R., Delugin, M., Bouchecareilh, M., Magnin, N., Favereaux, A., Maitre, M., Gaiser, T., von Deimling, A., Czabanka, M., Vajkoczy, P., Chevet, E., Bikfalvi, A., Moenner, M., Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma. Proc. Natl. Acad. Sci. USA 107 (2010), 15553–15558.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 15553-15558
-
-
Auf, G.1
Jabouille, A.2
Guerit, S.3
Pineau, R.4
Delugin, M.5
Bouchecareilh, M.6
Magnin, N.7
Favereaux, A.8
Maitre, M.9
Gaiser, T.10
von Deimling, A.11
Czabanka, M.12
Vajkoczy, P.13
Chevet, E.14
Bikfalvi, A.15
Moenner, M.16
-
7
-
-
84890002163
-
High epiregulin expression in human U87 glioma cells relies on IRE1alpha and promotes autocrine growth through EGF receptor
-
Auf, G., Jabouille, A., Delugin, M., Guerit, S., Pineau, R., North, S., Platonova, N., Maitre, M., Favereaux, A., Vajkoczy, P., Seno, M., Bikfalvi, A., Minchenko, D., Minchenko, O., Moenner, M., High epiregulin expression in human U87 glioma cells relies on IRE1alpha and promotes autocrine growth through EGF receptor. BMC Cancer, 13, 2013, 597.
-
(2013)
BMC Cancer
, vol.13
, pp. 597
-
-
Auf, G.1
Jabouille, A.2
Delugin, M.3
Guerit, S.4
Pineau, R.5
North, S.6
Platonova, N.7
Maitre, M.8
Favereaux, A.9
Vajkoczy, P.10
Seno, M.11
Bikfalvi, A.12
Minchenko, D.13
Minchenko, O.14
Moenner, M.15
-
8
-
-
67649450485
-
Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells
-
Back, S.H., Scheuner, D., Han, J., Song, B., Ribick, M., Wang, J., Gildersleeve, R.D., Pennathur, S., Kaufman, R.J., Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells. Cell. Metab. 10 (2009), 13–26.
-
(2009)
Cell. Metab.
, vol.10
, pp. 13-26
-
-
Back, S.H.1
Scheuner, D.2
Han, J.3
Song, B.4
Ribick, M.5
Wang, J.6
Gildersleeve, R.D.7
Pennathur, S.8
Kaufman, R.J.9
-
9
-
-
33644515957
-
Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury
-
Bailly-Maitre, B., Fondevila, C., Kaldas, F., Droin, N., Luciano, F., Ricci, J.E., Croxton, R., Krajewska, M., Zapata, J.M., Kupiec-Weglinski, J.W., Farmer, D., Reed, J.C., Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury. Proc. Natl. Acad. Sci. USA 103 (2006), 2809–2814.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2809-2814
-
-
Bailly-Maitre, B.1
Fondevila, C.2
Kaldas, F.3
Droin, N.4
Luciano, F.5
Ricci, J.E.6
Croxton, R.7
Krajewska, M.8
Zapata, J.M.9
Kupiec-Weglinski, J.W.10
Farmer, D.11
Reed, J.C.12
-
10
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch, W.E., Morimoto, R.I., Dillin, A., Kelly, J.W., Adapting proteostasis for disease intervention. Science 319 (2008), 916–919.
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
11
-
-
0028808309
-
Neurodegeneration and diabetes: UK nationwide study of Wolfram (DIDMOAD) syndrome
-
Barrett, T.G., Bundey, S.E., Macleod, A.F., Neurodegeneration and diabetes: UK nationwide study of Wolfram (DIDMOAD) syndrome. Lancet 346 (1995), 1458–1463.
-
(1995)
Lancet
, vol.346
, pp. 1458-1463
-
-
Barrett, T.G.1
Bundey, S.E.2
Macleod, A.F.3
-
12
-
-
78650510736
-
Proteomic insights into the protective mechanisms of an in vitro oxidative stress model of early stage Parkinson׳s disease
-
Bauereis, B., Haskins, W.E., Lebaron, R.G., Renthal, R., Proteomic insights into the protective mechanisms of an in vitro oxidative stress model of early stage Parkinson׳s disease. Neurosci. Lett. 488 (2011), 11–16.
-
(2011)
Neurosci. Lett.
, vol.488
, pp. 11-16
-
-
Bauereis, B.1
Haskins, W.E.2
Lebaron, R.G.3
Renthal, R.4
-
13
-
-
1342285215
-
Effect of the proteasome inhibitor MLN519 on the expression of inflammatory molecules following middle cerebral artery occlusion and reperfusion in the rat
-
Berti, R., Williams, A.J., Velarde, L.C., Moffett, J.R., Elliott, P.J., Adams, J., Yao, C., Dave, J.R., Tortella, F.C., Effect of the proteasome inhibitor MLN519 on the expression of inflammatory molecules following middle cerebral artery occlusion and reperfusion in the rat. Neurotox. Res. 5 (2003), 505–514.
-
(2003)
Neurotox. Res.
, vol.5
, pp. 505-514
-
-
Berti, R.1
Williams, A.J.2
Velarde, L.C.3
Moffett, J.R.4
Elliott, P.J.5
Adams, J.6
Yao, C.7
Dave, J.R.8
Tortella, F.C.9
-
14
-
-
41149174763
-
Mechanistic role of calpains in postischemic neurodegeneration
-
Bevers, M.B., Neumar, R.W., Mechanistic role of calpains in postischemic neurodegeneration. J. Cereb. Blood Flow Metab. 28 (2008), 655–673.
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, pp. 655-673
-
-
Bevers, M.B.1
Neumar, R.W.2
-
15
-
-
84901255107
-
Impairment of visual function and retinal ER stress activation in Wfs1-deficient mice
-
Bonnet Wersinger, D., Benkafadar, N., Jagodzinska, J., Hamel, C., Tanizawa, Y., Lenaers, G., Delettre, C., Impairment of visual function and retinal ER stress activation in Wfs1-deficient mice. Plos One, 9, 2014, e97222.
-
(2014)
Plos One
, vol.9
, pp. e97222
-
-
Bonnet Wersinger, D.1
Benkafadar, N.2
Jagodzinska, J.3
Hamel, C.4
Tanizawa, Y.5
Lenaers, G.6
Delettre, C.7
-
16
-
-
79954417075
-
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress
-
Bouman, L., Schlierf, A., Lutz, A.K., Shan, J., Deinlein, A., Kast, J., Galehdar, Z., Palmisano, V., Patenge, N., Berg, D., Gasser, T., Augustin, R., Trumbach, D., Irrcher, I., Park, D.S., Wurst, W., Kilberg, M.S., Tatzelt, J., Winklhofer, K.F., Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress. Cell Death Differ. 18 (2011), 769–782.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 769-782
-
-
Bouman, L.1
Schlierf, A.2
Lutz, A.K.3
Shan, J.4
Deinlein, A.5
Kast, J.6
Galehdar, Z.7
Palmisano, V.8
Patenge, N.9
Berg, D.10
Gasser, T.11
Augustin, R.12
Trumbach, D.13
Irrcher, I.14
Park, D.S.15
Wurst, W.16
Kilberg, M.S.17
Tatzelt, J.18
Winklhofer, K.F.19
-
17
-
-
13644256191
-
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress
-
Boyce, M., Bryant, K.F., Jousse, C., Long, K., Harding, H.P., Scheuner, D., Kaufman, R.J., Ma, D., Coen, D.M., Ron, D., Yuan, J., A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science. 307 (2005), 935–939.
-
(2005)
Science.
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
Kaufman, R.J.7
Ma, D.8
Coen, D.M.9
Ron, D.10
Yuan, J.11
-
18
-
-
58149347130
-
Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex
-
Bull, R., Finkelstein, J.P., Galvez, J., Sanchez, G., Donoso, P., Behrens, M.I., Hidalgo, C., Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex. J. Neurosci. 28 (2008), 9463–9472.
-
(2008)
J. Neurosci.
, vol.28
, pp. 9463-9472
-
-
Bull, R.1
Finkelstein, J.P.2
Galvez, J.3
Sanchez, G.4
Donoso, P.5
Behrens, M.I.6
Hidalgo, C.7
-
19
-
-
84922006768
-
Hormesis: from mainstream to therapy
-
Calabrese, E.J., Hormesis: from mainstream to therapy. J. Cell Commun. Signal 8 (2014), 289–291.
-
(2014)
J. Cell Commun. Signal
, vol.8
, pp. 289-291
-
-
Calabrese, E.J.1
-
20
-
-
84956941939
-
Preconditioning is hormesis part I: Documentation, dose–response features and mechanistic foundations
-
Calabrese, E.J., Preconditioning is hormesis part I: Documentation, dose–response features and mechanistic foundations. Pharmacol Res. 110 (2016), 242–264.
-
(2016)
Pharmacol Res.
, vol.110
, pp. 242-264
-
-
Calabrese, E.J.1
-
21
-
-
84954289994
-
Preconditioning is hormesis part II: How the conditioning dose mediates protection: Dose optimization within temporal and mechanistic frameworks
-
Calabrese, E.J., Preconditioning is hormesis part II: How the conditioning dose mediates protection: Dose optimization within temporal and mechanistic frameworks. Pharmacol Res. 110 (2016), 265–275.
-
(2016)
Pharmacol Res.
, vol.110
, pp. 265-275
-
-
Calabrese, E.J.1
-
22
-
-
84890805926
-
Role of the ubiquitin–proteasome system in brain ischemia: friend or foe?
-
Caldeira, M.V., Salazar, I.L., Curcio, M., Canzoniero, L.M., Duarte, C.B., Role of the ubiquitin–proteasome system in brain ischemia: friend or foe?. Prog. Neurobiol. 112 (2014), 50–69.
-
(2014)
Prog. Neurobiol.
, vol.112
, pp. 50-69
-
-
Caldeira, M.V.1
Salazar, I.L.2
Curcio, M.3
Canzoniero, L.M.4
Duarte, C.B.5
-
23
-
-
56349126024
-
Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury
-
Carloni, S., Buonocore, G., Balduini, W., Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. Neurobiol. Dis. 32 (2008), 329–339.
-
(2008)
Neurobiol. Dis.
, vol.32
, pp. 329-339
-
-
Carloni, S.1
Buonocore, G.2
Balduini, W.3
-
24
-
-
84896475043
-
Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: role of protein synthesis and autophagic pathways
-
Carloni, S., Albertini, M.C., Galluzzi, L., Buonocore, G., Proietti, F., Balduini, W., Increased autophagy reduces endoplasmic reticulum stress after neonatal hypoxia-ischemia: role of protein synthesis and autophagic pathways. Exp. Neurol. 255 (2014), 103–112.
-
(2014)
Exp. Neurol.
, vol.255
, pp. 103-112
-
-
Carloni, S.1
Albertini, M.C.2
Galluzzi, L.3
Buonocore, G.4
Proietti, F.5
Balduini, W.6
-
25
-
-
80455173839
-
BAX inhibitor-1 regulates autophagy by controlling the IRE1alpha branch of the unfolded protein response
-
Castillo, K., Rojas-Rivera, D., Lisbona, F., Caballero, B., Nassif, M., Court, F.A., Schuck, S., Ibar, C., Walter, P., Sierralta, J., Glavic, A., Hetz, C., BAX inhibitor-1 regulates autophagy by controlling the IRE1alpha branch of the unfolded protein response. Embo J. 30:21 (2011), 4465–4478.
-
(2011)
Embo J.
, vol.30
, Issue.21
, pp. 4465-4478
-
-
Castillo, K.1
Rojas-Rivera, D.2
Lisbona, F.3
Caballero, B.4
Nassif, M.5
Court, F.A.6
Schuck, S.7
Ibar, C.8
Walter, P.9
Sierralta, J.10
Glavic, A.11
Hetz, C.12
-
26
-
-
84938262536
-
Gene therapy in Parkinson׳s disease: targeting the endplasmic reticulum proteostasis network
-
Castillo, V., Mercado, G., Hetz, C., Gene therapy in Parkinson׳s disease: targeting the endplasmic reticulum proteostasis network. Neural Regen. Res. 10 (2015), 1053–1054.
-
(2015)
Neural Regen. Res.
, vol.10
, pp. 1053-1054
-
-
Castillo, V.1
Mercado, G.2
Hetz, C.3
-
27
-
-
0345059069
-
Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast
-
Chae, H.J., Ke, N., Kim, H.R., Chen, S., Godzik, A., Dickman, M., Reed, J.C., Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene 323 (2003), 101–113.
-
(2003)
Gene
, vol.323
, pp. 101-113
-
-
Chae, H.J.1
Ke, N.2
Kim, H.R.3
Chen, S.4
Godzik, A.5
Dickman, M.6
Reed, J.C.7
-
28
-
-
4143087106
-
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
-
Chae, H.J., Kim, H.R., Xu, C., Bailly-Maitre, B., Krajewska, M., Krajewski, S., Banares, S., Cui, J., Digicaylioglu, M., Ke, N., Kitada, S., Monosov, E., Thomas, M., Kress, C.L., Babendure, J.R., Tsien, R.Y., Lipton, S.A., Reed, J.C., BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol. Cell. 15 (2004), 355–366.
-
(2004)
Mol. Cell.
, vol.15
, pp. 355-366
-
-
Chae, H.J.1
Kim, H.R.2
Xu, C.3
Bailly-Maitre, B.4
Krajewska, M.5
Krajewski, S.6
Banares, S.7
Cui, J.8
Digicaylioglu, M.9
Ke, N.10
Kitada, S.11
Monosov, E.12
Thomas, M.13
Kress, C.L.14
Babendure, J.R.15
Tsien, R.Y.16
Lipton, S.A.17
Reed, J.C.18
-
29
-
-
84975796689
-
Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis
-
Chevet, E., Hetz, C., Samali, A., Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis. Cancer Discov. 5 (2015), 586–597.
-
(2015)
Cancer Discov.
, vol.5
, pp. 586-597
-
-
Chevet, E.1
Hetz, C.2
Samali, A.3
-
30
-
-
84947584380
-
Impacts of tissue-type plasminogen activator (tPA) on neuronal survival
-
Chevilley, A., Lesept, F., Lenoir, S., Ali, C., Parcq, J., Vivien, D., Impacts of tissue-type plasminogen activator (tPA) on neuronal survival. Front. Cell Neurosci., 9, 2015, 415.
-
(2015)
Front. Cell Neurosci.
, vol.9
, pp. 415
-
-
Chevilley, A.1
Lesept, F.2
Lenoir, S.3
Ali, C.4
Parcq, J.5
Vivien, D.6
-
31
-
-
84859597470
-
Hypothermia for acute brain injury–mechanisms and practical aspects
-
Choi, H.A., Badjatia, N., Mayer, S.A., Hypothermia for acute brain injury–mechanisms and practical aspects. Nat. Rev. Neurol. 8 (2012), 214–222.
-
(2012)
Nat. Rev. Neurol.
, vol.8
, pp. 214-222
-
-
Choi, H.A.1
Badjatia, N.2
Mayer, S.A.3
-
32
-
-
84888070126
-
Identification and rescue of alpha-synuclein toxicity in Parkinson patient-derived neurons
-
Chung, C.Y., Khurana, V., Auluck, P.K., Tardiff, D.F., Mazzulli, J.R., Soldner, F., Baru, V., Lou, Y., Freyzon, Y., Cho, S., Mungenast, A.E., Muffat, J., Mitalipova, M., Pluth, M.D., Jui, N.T., Schule, B., Lippard, S.J., Tsai, L.H., Krainc, D., Buchwald, S.L., Jaenisch, R., Lindquist, S., Identification and rescue of alpha-synuclein toxicity in Parkinson patient-derived neurons. Science 342 (2013), 983–987.
-
(2013)
Science
, vol.342
, pp. 983-987
-
-
Chung, C.Y.1
Khurana, V.2
Auluck, P.K.3
Tardiff, D.F.4
Mazzulli, J.R.5
Soldner, F.6
Baru, V.7
Lou, Y.8
Freyzon, Y.9
Cho, S.10
Mungenast, A.E.11
Muffat, J.12
Mitalipova, M.13
Pluth, M.D.14
Jui, N.T.15
Schule, B.16
Lippard, S.J.17
Tsai, L.H.18
Krainc, D.19
Buchwald, S.L.20
Jaenisch, R.21
Lindquist, S.22
more..
-
33
-
-
84929086199
-
The unravelling of the ubiquitin system
-
Ciechanover, A., The unravelling of the ubiquitin system. Nat. Rev. Mol. Cell Biol. 16 (2015), 322–324.
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 322-324
-
-
Ciechanover, A.1
-
34
-
-
84989284335
-
Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
-
Ciechanover, A., Kwon, Y.T., Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies. Exp. Mol. Med., 47, 2015, e147.
-
(2015)
Exp. Mol. Med.
, vol.47
, pp. e147
-
-
Ciechanover, A.1
Kwon, Y.T.2
-
35
-
-
78650100616
-
Ubiquitin: same molecule, different degradation pathways
-
Clague, M.J., Urbe, S., Ubiquitin: same molecule, different degradation pathways. Cell 143 (2010), 682–685.
-
(2010)
Cell
, vol.143
, pp. 682-685
-
-
Clague, M.J.1
Urbe, S.2
-
36
-
-
33947510911
-
Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis
-
Cnop, M., Ladriere, L., Hekerman, P., Ortis, F., Cardozo, A.K., Dogusan, Z., Flamez, D., Boyce, M., Yuan, J., Eizirik, D.L., Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis. J. Biol. Chem. 282 (2007), 3989–3997.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 3989-3997
-
-
Cnop, M.1
Ladriere, L.2
Hekerman, P.3
Ortis, F.4
Cardozo, A.K.5
Dogusan, Z.6
Flamez, D.7
Boyce, M.8
Yuan, J.9
Eizirik, D.L.10
-
37
-
-
84901053043
-
Physiological roles of regulated Ire1 dependent decay
-
Coelho, D.S., Domingos, P.M., Physiological roles of regulated Ire1 dependent decay. Front. Genet., 5, 2014, 76.
-
(2014)
Front. Genet.
, vol.5
, pp. 76
-
-
Coelho, D.S.1
Domingos, P.M.2
-
38
-
-
84863230467
-
Endoplasmic reticulum stress is important for the manifestations of alpha-synucleinopathy in vivo
-
Colla, E., Coune, P., Liu, Y., Pletnikova, O., Troncoso, J.C., Iwatsubo, T., Schneider, B.L., Lee, M.K., Endoplasmic reticulum stress is important for the manifestations of alpha-synucleinopathy in vivo. J. Neurosci. 32 (2012), 3306–3320.
-
(2012)
J. Neurosci.
, vol.32
, pp. 3306-3320
-
-
Colla, E.1
Coune, P.2
Liu, Y.3
Pletnikova, O.4
Troncoso, J.C.5
Iwatsubo, T.6
Schneider, B.L.7
Lee, M.K.8
-
39
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease
-
Conway, K.A., Harper, J.D., Lansbury, P.T., Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease. Nat. Med. 4 (1998), 1318–1320.
-
(1998)
Nat. Med.
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
40
-
-
33746533924
-
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson׳s models
-
Cooper, A.A., Gitler, A.D., Cashikar, A., Haynes, C.M., Hill, K.J., Bhullar, B., Liu, K., Xu, K., Strathearn, K.E., Liu, F., Cao, S., Caldwell, K.A., Caldwell, G.A., Marsischky, G., Kolodner, R.D., Labaer, J., Rochet, J.C., Bonini, N.M., Lindquist, S., Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson׳s models. Science 313 (2006), 324–328.
-
(2006)
Science
, vol.313
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
Haynes, C.M.4
Hill, K.J.5
Bhullar, B.6
Liu, K.7
Xu, K.8
Strathearn, K.E.9
Liu, F.10
Cao, S.11
Caldwell, K.A.12
Caldwell, G.A.13
Marsischky, G.14
Kolodner, R.D.15
Labaer, J.16
Rochet, J.C.17
Bonini, N.M.18
Lindquist, S.19
-
41
-
-
10044292870
-
Chronic exposure to rotenone models sporadic Parkinson׳s disease in Drosophila melanogaster
-
Coulom, H., Birman, S., Chronic exposure to rotenone models sporadic Parkinson׳s disease in Drosophila melanogaster. J. Neurosci. 24 (2004), 10993–10998.
-
(2004)
J. Neurosci.
, vol.24
, pp. 10993-10998
-
-
Coulom, H.1
Birman, S.2
-
42
-
-
84923871028
-
alpha-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson׳s disease
-
Credle, J.J., Forcelli, P.A., Delannoy, M., Oaks, A.W., Permaul, E., Berry, D.L., Duka, V., Wills, J., Sidhu, A., alpha-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson׳s disease. Neurobiol. Dis. 76 (2015), 112–125.
-
(2015)
Neurobiol. Dis.
, vol.76
, pp. 112-125
-
-
Credle, J.J.1
Forcelli, P.A.2
Delannoy, M.3
Oaks, A.W.4
Permaul, E.5
Berry, D.L.6
Duka, V.7
Wills, J.8
Sidhu, A.9
-
43
-
-
84957649544
-
The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma
-
Dadey, D.Y., Kapoor, V., Khudanyan, A., Urano, F., Kim, A.H., Thotala, D., Hallahan, D.E., The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma. Oncotarget 7 (2016), 2080–2092.
-
(2016)
Oncotarget
, vol.7
, pp. 2080-2092
-
-
Dadey, D.Y.1
Kapoor, V.2
Khudanyan, A.3
Urano, F.4
Kim, A.H.5
Thotala, D.6
Hallahan, D.E.7
-
44
-
-
4744344331
-
Cerebral ischemia and the unfolded protein response
-
DeGracia, D.J., Montie, H.L., Cerebral ischemia and the unfolded protein response. J. Neurochem. 91 (2004), 1–8.
-
(2004)
J. Neurochem.
, vol.91
, pp. 1-8
-
-
DeGracia, D.J.1
Montie, H.L.2
-
45
-
-
84872173393
-
Autocrine control of glioma cells adhesion and migration through IRE1alpha-mediated cleavage of SPARC mRNA
-
Dejeans, N., Pluquet, O., Lhomond, S., Grise, F., Bouchecareilh, M., Juin, A., Meynard-Cadars, M., Bidaud-Meynard, A., Gentil, C., Moreau, V., Saltel, F., Chevet, E., Autocrine control of glioma cells adhesion and migration through IRE1alpha-mediated cleavage of SPARC mRNA. J. Cell. Sci. 125 (2012), 4278–4287.
-
(2012)
J. Cell. Sci.
, vol.125
, pp. 4278-4287
-
-
Dejeans, N.1
Pluquet, O.2
Lhomond, S.3
Grise, F.4
Bouchecareilh, M.5
Juin, A.6
Meynard-Cadars, M.7
Bidaud-Meynard, A.8
Gentil, C.9
Moreau, V.10
Saltel, F.11
Chevet, E.12
-
46
-
-
84856977664
-
The ubiquitin proteasome system in neurodegenerative diseases: culprit, accomplice or victim?
-
Dennissen, F.J., Kholod, N., van Leeuwen, F.W., The ubiquitin proteasome system in neurodegenerative diseases: culprit, accomplice or victim?. Prog. Neurobiol. 96 (2012), 190–207.
-
(2012)
Prog. Neurobiol.
, vol.96
, pp. 190-207
-
-
Dennissen, F.J.1
Kholod, N.2
van Leeuwen, F.W.3
-
47
-
-
84937546424
-
Endovascular mechanical thrombectomy for acute ischemic stroke: a new standard of care
-
Ding, D., Endovascular mechanical thrombectomy for acute ischemic stroke: a new standard of care. J. Stroke 17 (2015), 123–126.
-
(2015)
J. Stroke
, vol.17
, pp. 123-126
-
-
Ding, D.1
-
48
-
-
84870226746
-
The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis
-
Doeppner, T.R., Mlynarczuk-Bialy, I., Kuckelkorn, U., Kaltwasser, B., Herz, J., Hasan, M.R., Hermann, D.M., Bahr, M., The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis. Brain 135 (2012), 3282–3297.
-
(2012)
Brain
, vol.135
, pp. 3282-3297
-
-
Doeppner, T.R.1
Mlynarczuk-Bialy, I.2
Kuckelkorn, U.3
Kaltwasser, B.4
Herz, J.5
Hasan, M.R.6
Hermann, D.M.7
Bahr, M.8
-
49
-
-
84881095655
-
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation
-
Doeppner, T.R., Doehring, M., Bretschneider, E., Zechariah, A., Kaltwasser, B., Muller, B., Koch, J.C., Bahr, M., Hermann, D.M., Michel, U., MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. Acta Neuropathol. 126 (2013), 251–265.
-
(2013)
Acta Neuropathol.
, vol.126
, pp. 251-265
-
-
Doeppner, T.R.1
Doehring, M.2
Bretschneider, E.3
Zechariah, A.4
Kaltwasser, B.5
Muller, B.6
Koch, J.C.7
Bahr, M.8
Hermann, D.M.9
Michel, U.10
-
50
-
-
84992711463
-
Systemic proteasome inhibition induces sustained post-stroke neurological recovery and neuroprotection via mechanisms involving reversal of peripheral immunosuppression and preservation of blood-brain-barrier integrity
-
Epub ahead of print
-
Doeppner, T.R., Kaltwasser, B., Kuckelkorn, U., Henkelein, P., Bretschneider, E., Kilic, E., Hermann, D.M., Systemic proteasome inhibition induces sustained post-stroke neurological recovery and neuroprotection via mechanisms involving reversal of peripheral immunosuppression and preservation of blood-brain-barrier integrity. Mol. Neurobiol., 2015 Epub ahead of print.
-
(2015)
Mol. Neurobiol.
-
-
Doeppner, T.R.1
Kaltwasser, B.2
Kuckelkorn, U.3
Henkelein, P.4
Bretschneider, E.5
Kilic, E.6
Hermann, D.M.7
-
51
-
-
46349090692
-
Mechanisms of ischemic brain damage
-
Doyle, K.P., Simon, R.P., Stenzel-Poore, M.P., Mechanisms of ischemic brain damage. Neuropharmacology 55 (2008), 310–318.
-
(2008)
Neuropharmacology
, vol.55
, pp. 310-318
-
-
Doyle, K.P.1
Simon, R.P.2
Stenzel-Poore, M.P.3
-
52
-
-
34547114745
-
IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-a expression and contributes to angiogenesis and tumor growth in vivo
-
Drogat, B., Auguste, P., Nguyen, D.T., Bouchecareilh, M., Pineau, R., Nalbantoglu, J., Kaufman, R.J., Chevet, E., Bikfalvi, A., Moenner, M., IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-a expression and contributes to angiogenesis and tumor growth in vivo. Cancer Res. 67 (2007), 6700–6707.
-
(2007)
Cancer Res.
, vol.67
, pp. 6700-6707
-
-
Drogat, B.1
Auguste, P.2
Nguyen, D.T.3
Bouchecareilh, M.4
Pineau, R.5
Nalbantoglu, J.6
Kaufman, R.J.7
Chevet, E.8
Bikfalvi, A.9
Moenner, M.10
-
53
-
-
79953148080
-
The endoplasmic reticulum stress sensor, ATF6alpha, protects against neurotoxin-induced dopaminergic neuronal death
-
Egawa, N., Yamamoto, K., Inoue, H., Hikawa, R., Nishi, K., Mori, K., Takahashi, R., The endoplasmic reticulum stress sensor, ATF6alpha, protects against neurotoxin-induced dopaminergic neuronal death. J. Biol. Chem. 286 (2011), 7947–7957.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 7947-7957
-
-
Egawa, N.1
Yamamoto, K.2
Inoue, H.3
Hikawa, R.4
Nishi, K.5
Mori, K.6
Takahashi, R.7
-
54
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley, D., Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 78 (2009), 477–513.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
55
-
-
70449494871
-
Endoplasmic reticulum stress in beta-cells and development of diabetes
-
Fonseca, S.G., Burcin, M., Gromada, J., Urano, F., Endoplasmic reticulum stress in beta-cells and development of diabetes. Curr. Opin. Pharmacol. 9 (2009), 763–770.
-
(2009)
Curr. Opin. Pharmacol.
, vol.9
, pp. 763-770
-
-
Fonseca, S.G.1
Burcin, M.2
Gromada, J.3
Urano, F.4
-
56
-
-
77949751415
-
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells
-
Fonseca, S.G., Ishigaki, S., Oslowski, C.M., Lu, S., Lipson, K.L., Ghosh, R., Hayashi, E., Ishihara, H., Oka, Y., Permutt, M.A., Urano, F., Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells. J. Clin. Investig. 120 (2010), 744–755.
-
(2010)
J. Clin. Investig.
, vol.120
, pp. 744-755
-
-
Fonseca, S.G.1
Ishigaki, S.2
Oslowski, C.M.3
Lu, S.4
Lipson, K.L.5
Ghosh, R.6
Hayashi, E.7
Ishihara, H.8
Oka, Y.9
Permutt, M.A.10
Urano, F.11
-
57
-
-
84862303631
-
ER stress inhibits neuronal death by promoting autophagy
-
Fouillet, A., Levet, C., Virgone, A., Robin, M., Dourlen, P., Rieusset, J., Belaidi, E., Ovize, M., Touret, M., Nataf, S., Mollereau, B., ER stress inhibits neuronal death by promoting autophagy. Autophagy 8 (2012), 915–926.
-
(2012)
Autophagy
, vol.8
, pp. 915-926
-
-
Fouillet, A.1
Levet, C.2
Virgone, A.3
Robin, M.4
Dourlen, P.5
Rieusset, J.6
Belaidi, E.7
Ovize, M.8
Touret, M.9
Nataf, S.10
Mollereau, B.11
-
58
-
-
6344236867
-
Tissue plasminogen activator is a potent activator of PDGF-CC
-
Fredriksson, L., Li, H., Fieber, C., Li, X., Eriksson, U., Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J. 23 (2004), 3793–3802.
-
(2004)
EMBO J.
, vol.23
, pp. 3793-3802
-
-
Fredriksson, L.1
Li, H.2
Fieber, C.3
Li, X.4
Eriksson, U.5
-
59
-
-
0028126611
-
Tissue-type plasminogen activator (tPA) is the main plasminogen activator associated with isolated rat nerve growth cones
-
Garcia-Rocha, M., Avila, J., Armas-Portela, R., Tissue-type plasminogen activator (tPA) is the main plasminogen activator associated with isolated rat nerve growth cones. Neurosci. Lett. 180 (1994), 123–126.
-
(1994)
Neurosci. Lett.
, vol.180
, pp. 123-126
-
-
Garcia-Rocha, M.1
Avila, J.2
Armas-Portela, R.3
-
60
-
-
38349160161
-
The Parkinson׳s disease protein alpha-synuclein disrupts cellular Rab homeostasis
-
Gitler, A.D., Bevis, B.J., Shorter, J., Strathearn, K.E., Hamamichi, S., Su, L.J., Caldwell, K.A., Caldwell, G.A., Rochet, J.C., McCaffery, J.M., Barlowe, C., Lindquist, S., The Parkinson׳s disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proc. Natl. Acad. Sci. USA. 105 (2008), 145–150.
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 145-150
-
-
Gitler, A.D.1
Bevis, B.J.2
Shorter, J.3
Strathearn, K.E.4
Hamamichi, S.5
Su, L.J.6
Caldwell, K.A.7
Caldwell, G.A.8
Rochet, J.C.9
McCaffery, J.M.10
Barlowe, C.11
Lindquist, S.12
-
61
-
-
0036083396
-
The ubiquitin–proteasome proteolytic pathway: destruction for the sake of construction
-
Glickman, M.H., Ciechanover, A., The ubiquitin–proteasome proteolytic pathway: destruction for the sake of construction. Physiol. Rev. 82 (2002), 373–428.
-
(2002)
Physiol. Rev.
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
62
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
Goldberg, A.L., Protein degradation and protection against misfolded or damaged proteins. Nature 426 (2003), 895–899.
-
(2003)
Nature
, vol.426
, pp. 895-899
-
-
Goldberg, A.L.1
-
63
-
-
84863498486
-
Glucose regulated protein 78 diminishes alpha-synuclein neurotoxicity in a rat model of Parkinson disease
-
Gorbatyuk, M.S., Shabashvili, A., Chen, W., Meyers, C., Sullivan, L.F., Salganik, M., Lin, J.H., Lewin, A.S., Muzyczka, N., Gorbatyuk, O.S., Glucose regulated protein 78 diminishes alpha-synuclein neurotoxicity in a rat model of Parkinson disease. Mol. Ther. 20 (2012), 1327–1337.
-
(2012)
Mol. Ther.
, vol.20
, pp. 1327-1337
-
-
Gorbatyuk, M.S.1
Shabashvili, A.2
Chen, W.3
Meyers, C.4
Sullivan, L.F.5
Salganik, M.6
Lin, J.H.7
Lewin, A.S.8
Muzyczka, N.9
Gorbatyuk, O.S.10
-
64
-
-
4344677922
-
Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and ׳aggresomes׳ during oxidative stress, aging, and disease
-
Grune, T., Jung, T., Merker, K., Davies, K.J., Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and ׳aggresomes׳ during oxidative stress, aging, and disease. Int. J Biochem. Cell. Biol. 36 (2004), 2519–2530.
-
(2004)
Int. J Biochem. Cell. Biol.
, vol.36
, pp. 2519-2530
-
-
Grune, T.1
Jung, T.2
Merker, K.3
Davies, K.J.4
-
65
-
-
77955044180
-
HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction
-
Gupta, S., Deepti, A., Deegan, S., Lisbona, F., Hetz, C., Samali, A., HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. Plos. Biol., 8, 2010, e1000410.
-
(2010)
Plos. Biol.
, vol.8
, pp. e1000410
-
-
Gupta, S.1
Deepti, A.2
Deegan, S.3
Lisbona, F.4
Hetz, C.5
Samali, A.6
-
66
-
-
77953715773
-
OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins
-
Hamed, H.A., Yacoub, A., Park, M.A., Eulitt, P., Sarkar, D., Dimitrie, I.P., Chen, C.S., Grant, S., Curiel, D.T., Fisher, P.B., Dent, P., OSU-03012 enhances Ad.7-induced GBM cell killing via ER stress and autophagy and by decreasing expression of mitochondrial protective proteins. Cancer Biol. Ther. 9 (2010), 526–536.
-
(2010)
Cancer Biol. Ther.
, vol.9
, pp. 526-536
-
-
Hamed, H.A.1
Yacoub, A.2
Park, M.A.3
Eulitt, P.4
Sarkar, D.5
Dimitrie, I.P.6
Chen, C.S.7
Grant, S.8
Curiel, D.T.9
Fisher, P.B.10
Dent, P.11
-
67
-
-
84877578475
-
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
-
Han, J., Back, S.H., Hur, J., Lin, Y.H., Gildersleeve, R., Shan, J., Yuan, C.L., Krokowski, D., Wang, S., Hatzoglou, M., Kilberg, M.S., Sartor, M.A., Kaufman, R.J., ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat. Cell. Biol. 15 (2013), 481–490.
-
(2013)
Nat. Cell. Biol.
, vol.15
, pp. 481-490
-
-
Han, J.1
Back, S.H.2
Hur, J.3
Lin, Y.H.4
Gildersleeve, R.5
Shan, J.6
Yuan, C.L.7
Krokowski, D.8
Wang, S.9
Hatzoglou, M.10
Kilberg, M.S.11
Sartor, M.A.12
Kaufman, R.J.13
-
68
-
-
84940557532
-
Antioxidants complement the requirement for protein chaperone function to maintain beta-cell function and glucose homeostasis
-
Han, J., Song, B., Kim, J., Kodali, V.K., Pottekat, A., Wang, M., Hassler, J., Wang, S., Pennathur, S., Back, S.H., Katze, M.G., Kaufman, R.J., Antioxidants complement the requirement for protein chaperone function to maintain beta-cell function and glucose homeostasis. Diabetes 64 (2015), 2892–2904.
-
(2015)
Diabetes
, vol.64
, pp. 2892-2904
-
-
Han, J.1
Song, B.2
Kim, J.3
Kodali, V.K.4
Pottekat, A.5
Wang, M.6
Hassler, J.7
Wang, S.8
Pennathur, S.9
Back, S.H.10
Katze, M.G.11
Kaufman, R.J.12
-
69
-
-
78650413857
-
Endoplasmic reticulum stress inducers provide protection against 6-hydroxydopamine-induced cytotoxicity
-
Hara, H., Kamiya, T., Adachi, T., Endoplasmic reticulum stress inducers provide protection against 6-hydroxydopamine-induced cytotoxicity. Neurochem. Int. 58 (2011), 35–43.
-
(2011)
Neurochem. Int.
, vol.58
, pp. 35-43
-
-
Hara, H.1
Kamiya, T.2
Adachi, T.3
-
70
-
-
60549114848
-
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development
-
Harding, H.P., Zhang, Y., Scheuner, D., Chen, J.J., Kaufman, R.J., Ron, D., Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development. Proc. Natl. Acad. Sci. USA 106 (2009), 1832–1837.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 1832-1837
-
-
Harding, H.P.1
Zhang, Y.2
Scheuner, D.3
Chen, J.J.4
Kaufman, R.J.5
Ron, D.6
-
71
-
-
77956917231
-
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
-
Hardingham, G.E., Bading, H., Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat. Rev. Neurosci. 11 (2010), 682–696.
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 682-696
-
-
Hardingham, G.E.1
Bading, H.2
-
72
-
-
84949233942
-
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
-
Hart, T., Chandrashekhar, M., Aregger, M., Steinhart, Z., Brown, K.R., MacLeod, G., Mis, M., Zimmermann, M., Fradet-Turcotte, A., Sun, S., Mero, P., Dirks, P., Sidhu, S., Roth, F.P., Rissland, O.S., Durocher, D., Angers, S., Moffat, J., High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities. Cell 163 (2015), 1515–1526.
-
(2015)
Cell
, vol.163
, pp. 1515-1526
-
-
Hart, T.1
Chandrashekhar, M.2
Aregger, M.3
Steinhart, Z.4
Brown, K.R.5
MacLeod, G.6
Mis, M.7
Zimmermann, M.8
Fradet-Turcotte, A.9
Sun, S.10
Mero, P.11
Dirks, P.12
Sidhu, S.13
Roth, F.P.14
Rissland, O.S.15
Durocher, D.16
Angers, S.17
Moffat, J.18
-
73
-
-
84868135034
-
ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson׳s disease
-
Hashida, K., Kitao, Y., Sudo, H., Awa, Y., Maeda, S., Mori, K., Takahashi, R., Iinuma, M., Hori, O., ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson׳s disease. Plos One, 7, 2012, e47950.
-
(2012)
Plos One
, vol.7
, pp. e47950
-
-
Hashida, K.1
Kitao, Y.2
Sudo, H.3
Awa, Y.4
Maeda, S.5
Mori, K.6
Takahashi, R.7
Iinuma, M.8
Hori, O.9
-
74
-
-
84932192250
-
Inside-out neuropharmacology of nicotinic drugs
-
Henderson, B.J., Lester, H.A., Inside-out neuropharmacology of nicotinic drugs. Neuropharmacology 96 (2015), 178–193.
-
(2015)
Neuropharmacology
, vol.96
, pp. 178-193
-
-
Henderson, B.J.1
Lester, H.A.2
-
75
-
-
70349627027
-
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
-
Hetz, C., Thielen, P., Matus, S., Nassif, M., Court, F., Kiffin, R., Martinez, G., Cuervo, A.M., Brown, R.H., Glimcher, L.H., XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev. 23 (2009), 2294–2306.
-
(2009)
Genes Dev.
, vol.23
, pp. 2294-2306
-
-
Hetz, C.1
Thielen, P.2
Matus, S.3
Nassif, M.4
Court, F.5
Kiffin, R.6
Martinez, G.7
Cuervo, A.M.8
Brown, R.H.9
Glimcher, L.H.10
-
76
-
-
80054722420
-
The unfolded protein response: integrating stress signals through the stress sensor IRE1alpha
-
Hetz, C., Martinon, F., Rodriguez, D., Glimcher, L.H., The unfolded protein response: integrating stress signals through the stress sensor IRE1alpha. Physiol. Rev. 91 (2011), 1219–1243.
-
(2011)
Physiol. Rev.
, vol.91
, pp. 1219-1243
-
-
Hetz, C.1
Martinon, F.2
Rodriguez, D.3
Glimcher, L.H.4
-
77
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
Hetz, C., Chevet, E., Harding, H.P., Targeting the unfolded protein response in disease. Nat. Rev. Drug Discov. 12 (2013), 703–719.
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
78
-
-
84897094564
-
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
-
Hetz, C., Mollereau, B., Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases. Nat. Rev. Neurosci. 15 (2014), 233–249.
-
(2014)
Nat. Rev. Neurosci.
, vol.15
, pp. 233-249
-
-
Hetz, C.1
Mollereau, B.2
-
79
-
-
84934275896
-
Proteostasis control by the unfolded protein response
-
Hetz, C., Chevet, E., Oakes, S.A., Proteostasis control by the unfolded protein response. Nat. Cell. Biol. 17 (2015), 829–838.
-
(2015)
Nat. Cell. Biol.
, vol.17
, pp. 829-838
-
-
Hetz, C.1
Chevet, E.2
Oakes, S.A.3
-
80
-
-
84873427263
-
Pathogenesis of Parkinson׳s disease
-
Hirsch, E.C., Jenner, P., Przedborski, S., Pathogenesis of Parkinson׳s disease. Mov. Disord. 28 (2013), 24–30.
-
(2013)
Mov. Disord.
, vol.28
, pp. 24-30
-
-
Hirsch, E.C.1
Jenner, P.2
Przedborski, S.3
-
81
-
-
84864277301
-
Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion
-
Hochrainer, K., Jackman, K., Anrather, J., Iadecola, C., Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion. Stroke 43 (2012), 2229–2235.
-
(2012)
Stroke
, vol.43
, pp. 2229-2235
-
-
Hochrainer, K.1
Jackman, K.2
Anrather, J.3
Iadecola, C.4
-
82
-
-
84856457578
-
Ischemic cerebral damage: an appraisal of synaptic failure
-
Hofmeijer, J., van Putten, M.J., Ischemic cerebral damage: an appraisal of synaptic failure. Stroke 43 (2012), 607–615.
-
(2012)
Stroke
, vol.43
, pp. 607-615
-
-
Hofmeijer, J.1
van Putten, M.J.2
-
83
-
-
33846605587
-
Activation of the unfolded protein response in Parkinson׳s disease
-
Hoozemans, J.J., van Haastert, E.S., Eikelenboom, P., de Vos, R.A., Rozemuller, J.M., Scheper, W., Activation of the unfolded protein response in Parkinson׳s disease. Biochem. Biophys. Res. Commun. 354 (2007), 707–711.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.354
, pp. 707-711
-
-
Hoozemans, J.J.1
van Haastert, E.S.2
Eikelenboom, P.3
de Vos, R.A.4
Rozemuller, J.M.5
Scheper, W.6
-
84
-
-
84860219621
-
Activation of the unfolded protein response is an early event in Alzheimer׳s and Parkinson׳s disease
-
Hoozemans, J.J., van Haastert, E.S., Nijholt, D.A., Rozemuller, A.J., Scheper, W., Activation of the unfolded protein response is an early event in Alzheimer׳s and Parkinson׳s disease. Neurodegener. Dis. 10 (2012), 212–215.
-
(2012)
Neurodegener. Dis.
, vol.10
, pp. 212-215
-
-
Hoozemans, J.J.1
van Haastert, E.S.2
Nijholt, D.A.3
Rozemuller, A.J.4
Scheper, W.5
-
85
-
-
84924546391
-
PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2׳s mitochondria translocation
-
Hou, X., Liu, Y., Liu, H., Chen, X., Liu, M., Che, H., Guo, F., Wang, C., Zhang, D., Wu, J., Shen, C., Li, C., Peng, F., Bi, Y., Yang, Z., Yang, G., Ai, J., Gao, X., Zhao, S., PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2׳s mitochondria translocation. Sci. Rep., 5, 2015, 9065.
-
(2015)
Sci. Rep.
, vol.5
, pp. 9065
-
-
Hou, X.1
Liu, Y.2
Liu, H.3
Chen, X.4
Liu, M.5
Che, H.6
Guo, F.7
Wang, C.8
Zhang, D.9
Wu, J.10
Shen, C.11
Li, C.12
Peng, F.13
Bi, Y.14
Yang, Z.15
Yang, G.16
Ai, J.17
Gao, X.18
Zhao, S.19
-
86
-
-
0034192398
-
Protein aggregation after transient cerebral ischemia
-
Hu, B.R., Martone, M.E., Jones, Y.Z., Liu, C.L., Protein aggregation after transient cerebral ischemia. J Neurosci. 20 (2000), 3191–3199.
-
(2000)
J Neurosci.
, vol.20
, pp. 3191-3199
-
-
Hu, B.R.1
Martone, M.E.2
Jones, Y.Z.3
Liu, C.L.4
-
87
-
-
0034963383
-
Protein aggregation after focal brain ischemia and reperfusion
-
Hu, B.R., Janelidze, S., Ginsberg, M.D., Busto, R., Perez-Pinzon, M., Sick, T.J., Siesjo, B.K., Liu, C.L., Protein aggregation after focal brain ischemia and reperfusion. J. Cereb. Blood Flow Metab. 21 (2001), 865–875.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 865-875
-
-
Hu, B.R.1
Janelidze, S.2
Ginsberg, M.D.3
Busto, R.4
Perez-Pinzon, M.5
Sick, T.J.6
Siesjo, B.K.7
Liu, C.L.8
-
88
-
-
84876903554
-
Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons
-
Huang, Q., Wang, H., Perry, S.W., Figueiredo-Pereira, M.E., Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons. J. Biol. Chem. 288 (2013), 12161–12174.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 12161-12174
-
-
Huang, Q.1
Wang, H.2
Perry, S.W.3
Figueiredo-Pereira, M.E.4
-
89
-
-
84874998766
-
The ubiquitin–proteasome system and the autophagic-lysosomal system in Alzheimer disease
-
Ihara, Y., Morishima-Kawashima, M., Nixon, R., The ubiquitin–proteasome system and the autophagic-lysosomal system in Alzheimer disease. Cold Spring Harb Perspect. Med., 2012, 2.
-
(2012)
Cold Spring Harb Perspect. Med.
, pp. 2
-
-
Ihara, Y.1
Morishima-Kawashima, M.2
Nixon, R.3
-
90
-
-
17344362695
-
A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)
-
Inoue, H., Tanizawa, Y., Wasson, J., Behn, P., Kalidas, K., Bernal-Mizrachi, E., Mueckler, M., Marshall, H., Donis-Keller, H., Crock, P., Rogers, D., Mikuni, M., Kumashiro, H., Higashi, K., Sobue, G., Oka, Y., Permutt, M.A., A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome). Nat. Genet. 20 (1998), 143–148.
-
(1998)
Nat. Genet.
, vol.20
, pp. 143-148
-
-
Inoue, H.1
Tanizawa, Y.2
Wasson, J.3
Behn, P.4
Kalidas, K.5
Bernal-Mizrachi, E.6
Mueckler, M.7
Marshall, H.8
Donis-Keller, H.9
Crock, P.10
Rogers, D.11
Mikuni, M.12
Kumashiro, H.13
Higashi, K.14
Sobue, G.15
Oka, Y.16
Permutt, M.A.17
-
91
-
-
84944474756
-
Glioblastoma invasion and cooption depend on IRE1alpha endoribonuclease activity
-
Jabouille, A., Delugin, M., Pineau, R., Dubrac, A., Soulet, F., Lhomond, S., Pallares-Lupon, N., Prats, H., Bikfalvi, A., Chevet, E., Touriol, C., Moenner, M., Glioblastoma invasion and cooption depend on IRE1alpha endoribonuclease activity. Oncotarget 6 (2015), 24922–24934.
-
(2015)
Oncotarget
, vol.6
, pp. 24922-24934
-
-
Jabouille, A.1
Delugin, M.2
Pineau, R.3
Dubrac, A.4
Soulet, F.5
Lhomond, S.6
Pallares-Lupon, N.7
Prats, H.8
Bikfalvi, A.9
Chevet, E.10
Touriol, C.11
Moenner, M.12
-
92
-
-
84887486172
-
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
-
Jin, S.M., Youle, R.J., The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 9 (2013), 1750–1757.
-
(2013)
Autophagy
, vol.9
, pp. 1750-1757
-
-
Jin, S.M.1
Youle, R.J.2
-
93
-
-
84932604466
-
IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions
-
Kanekura, K., Ma, X., Murphy, J.T., Zhu, L.J., Diwan, A., Urano, F., IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions. Sci. Signal, 8, 2015, ra62.
-
(2015)
Sci. Signal
, vol.8
, pp. ra62
-
-
Kanekura, K.1
Ma, X.2
Murphy, J.T.3
Zhu, L.J.4
Diwan, A.5
Urano, F.6
-
94
-
-
70350131291
-
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation
-
Kang, M.J., Ryoo, H.D., Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation. Proc. Natl. Acad. Sci. USA. 106 (2009), 17043–17048.
-
(2009)
Proc. Natl. Acad. Sci. USA.
, vol.106
, pp. 17043-17048
-
-
Kang, M.J.1
Ryoo, H.D.2
-
95
-
-
0037381710
-
Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease
-
Keck, S., Nitsch, R., Grune, T., Ullrich, O., Proteasome inhibition by paired helical filament-tau in brains of patients with Alzheimer's disease. J Neurochem. 85 (2003), 115–122.
-
(2003)
J Neurochem.
, vol.85
, pp. 115-122
-
-
Keck, S.1
Nitsch, R.2
Grune, T.3
Ullrich, O.4
-
96
-
-
85013763791
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
3rd ed
-
Klionsky, D.J., Abdelmohsen, K., Abe, A., Abedin, M.J., Abeliovich, H., Acevedo Arozena, A., Guidelines for the use and interpretation of assays for monitoring autophagy. 3rd ed Autophagy 12 (2016), 1–222.
-
(2016)
Autophagy
, vol.12
, pp. 1-222
-
-
Klionsky, D.J.1
Abdelmohsen, K.2
Abe, A.3
Abedin, M.J.4
Abeliovich, H.5
Acevedo Arozena, A.6
-
97
-
-
84899127068
-
The Caenorhabditis elegans HP1 family protein HPL-2 maintains ER homeostasis through the UPR and hormesis
-
Kozlowski, L., Garvis, S., Bedet, C., Palladino, F., The Caenorhabditis elegans HP1 family protein HPL-2 maintains ER homeostasis through the UPR and hormesis. Proc. Natl. Acad. Sci. USA. 111 (2014), 5956–5961.
-
(2014)
Proc. Natl. Acad. Sci. USA.
, vol.111
, pp. 5956-5961
-
-
Kozlowski, L.1
Garvis, S.2
Bedet, C.3
Palladino, F.4
-
98
-
-
78651364538
-
Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury
-
Krajewska, M., Xu, L., Xu, W., Krajewski, S., Kress, C.L., Cui, J., Yang, L., Irie, F., Yamaguchi, Y., Lipton, S.A., Reed, J.C., Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury. Brain Res. 1370 (2011), 227–237.
-
(2011)
Brain Res.
, vol.1370
, pp. 227-237
-
-
Krajewska, M.1
Xu, L.2
Xu, W.3
Krajewski, S.4
Kress, C.L.5
Cui, J.6
Yang, L.7
Irie, F.8
Yamaguchi, Y.9
Lipton, S.A.10
Reed, J.C.11
-
99
-
-
77149138303
-
Cross-talk of intracellular calcium stores in the response to neuronal ischemia and ischemic tolerance
-
Lehotsky, J., Racay, P., Pavlikova, M., Tatarkova, Z., Urban, P., Chomova, M., Kovalska, M., Kaplan, P., Cross-talk of intracellular calcium stores in the response to neuronal ischemia and ischemic tolerance. Gen. Physiol. Biophys. 28 Spec. No Focus (2009), F104–F114.
-
(2009)
Gen. Physiol. Biophys.
, vol.28 Spec. No Focus
, pp. F104-F114
-
-
Lehotsky, J.1
Racay, P.2
Pavlikova, M.3
Tatarkova, Z.4
Urban, P.5
Chomova, M.6
Kovalska, M.7
Kaplan, P.8
-
100
-
-
84855921310
-
tPA in the injured central nervous system: different scenarios starring the same actor?
-
Lemarchant, S., Docagne, F., Emery, E., Vivien, D., Ali, C., Rubio, M., tPA in the injured central nervous system: different scenarios starring the same actor?. Neuropharmacology 62 (2012), 749–756.
-
(2012)
Neuropharmacology
, vol.62
, pp. 749-756
-
-
Lemarchant, S.1
Docagne, F.2
Emery, E.3
Vivien, D.4
Ali, C.5
Rubio, M.6
-
101
-
-
84896259188
-
tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury
-
Lemarchant, S., Pruvost, M., Hebert, M., Gauberti, M., Hommet, Y., Briens, A., Maubert, E., Gueye, Y., Feron, F., Petite, D., Mersel, M., do Rego, J.C., Vaudry, H., Koistinaho, J., Ali, C., Agin, V., Emery, E., Vivien, D., tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury. Neurobiol. Dis. 66 (2014), 28–42.
-
(2014)
Neurobiol. Dis.
, vol.66
, pp. 28-42
-
-
Lemarchant, S.1
Pruvost, M.2
Hebert, M.3
Gauberti, M.4
Hommet, Y.5
Briens, A.6
Maubert, E.7
Gueye, Y.8
Feron, F.9
Petite, D.10
Mersel, M.11
do Rego, J.C.12
Vaudry, H.13
Koistinaho, J.14
Ali, C.15
Agin, V.16
Emery, E.17
Vivien, D.18
-
102
-
-
67349251869
-
Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants
-
Lessing, D., Bonini, N.M., Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants. Nat. Rev. Genet. 10 (2009), 359–370.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 359-370
-
-
Lessing, D.1
Bonini, N.M.2
-
103
-
-
84892906439
-
Inhibition of store-operated calcium entry attenuates MPP(+)-induced oxidative stress via preservation of mitochondrial function in PC12 cells: involvement of Homer1a
-
Li, X., Chen, W., Zhang, L., Liu, W.B., Fei, Z., Inhibition of store-operated calcium entry attenuates MPP(+)-induced oxidative stress via preservation of mitochondrial function in PC12 cells: involvement of Homer1a. Plos One, 8, 2013, e83638.
-
(2013)
Plos One
, vol.8
, pp. e83638
-
-
Li, X.1
Chen, W.2
Zhang, L.3
Liu, W.B.4
Fei, Z.5
-
104
-
-
84863106329
-
Ischaemic postconditioning rescues brain injury caused by focal ischaemia/reperfusion via attenuation of protein oxidization
-
Li, Z.Y., Liu, B., Yu, J., Yang, F.W., Luo, Y.N., Ge, P.F., Ischaemic postconditioning rescues brain injury caused by focal ischaemia/reperfusion via attenuation of protein oxidization. J. Int. Med. Res. 40 (2012), 954–966.
-
(2012)
J. Int. Med. Res.
, vol.40
, pp. 954-966
-
-
Li, Z.Y.1
Liu, B.2
Yu, J.3
Yang, F.W.4
Luo, Y.N.5
Ge, P.F.6
-
105
-
-
84871351347
-
Ischemic postconditioning protects neuronal death caused by cerebral ischemia and reperfusion via attenuating protein aggregation
-
Liang, J., Yao, J., Wang, G., Wang, Y., Wang, B., Ge, P., Ischemic postconditioning protects neuronal death caused by cerebral ischemia and reperfusion via attenuating protein aggregation. Int. J. Med. Sci. 9 (2012), 923–932.
-
(2012)
Int. J. Med. Sci.
, vol.9
, pp. 923-932
-
-
Liang, J.1
Yao, J.2
Wang, G.3
Wang, Y.4
Wang, B.5
Ge, P.6
-
106
-
-
62549129467
-
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha
-
Lisbona, F., Rojas-Rivera, D., Thielen, P., Zamorano, S., Todd, D., Martinon, F., Glavic, A., Kress, C., Lin, J.H., Walter, P., Reed, J.C., Glimcher, L.H., Hetz, C., BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol. Cell. 33 (2009), 679–691.
-
(2009)
Mol. Cell.
, vol.33
, pp. 679-691
-
-
Lisbona, F.1
Rojas-Rivera, D.2
Thielen, P.3
Zamorano, S.4
Todd, D.5
Martinon, F.6
Glavic, A.7
Kress, C.8
Lin, J.H.9
Walter, P.10
Reed, J.C.11
Glimcher, L.H.12
Hetz, C.13
-
107
-
-
23944494072
-
Co-translational protein aggregation after transient cerebral ischemia
-
Liu, C.L., Ge, P., Zhang, F., Hu, B.R., Co-translational protein aggregation after transient cerebral ischemia. Neuroscience 134 (2005), 1273–1284.
-
(2005)
Neuroscience
, vol.134
, pp. 1273-1284
-
-
Liu, C.L.1
Ge, P.2
Zhang, F.3
Hu, B.R.4
-
108
-
-
84936078040
-
Remote ischemic postconditioning alleviates cerebral ischemic injury by attenuating endoplasmic reticulum stress-mediated apoptosis
-
Liu, X., Zhao, S., Liu, F., Kang, J., Xiao, A., Li, F., Zhang, C., Yan, F., Zhao, H., Luo, M., Luo, Y., Ji, X., Remote ischemic postconditioning alleviates cerebral ischemic injury by attenuating endoplasmic reticulum stress-mediated apoptosis. Transl. Stroke Res. 5 (2014), 692–700.
-
(2014)
Transl. Stroke Res.
, vol.5
, pp. 692-700
-
-
Liu, X.1
Zhao, S.2
Liu, F.3
Kang, J.4
Xiao, A.5
Li, F.6
Zhang, C.7
Yan, F.8
Zhao, H.9
Luo, M.10
Luo, Y.11
Ji, X.12
-
109
-
-
34547122001
-
The 2007 WHO classification of tumours of the central nervous system
-
Louis, D.N., Ohgaki, H., Wiestler, O.D., Cavenee, W.K., Burger, P.C., Jouvet, A., Scheithauer, B.W., Kleihues, P., The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 114 (2007), 97–109.
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
Scheithauer, B.W.7
Kleihues, P.8
-
110
-
-
84916199287
-
A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome
-
Lu, S., Kanekura, K., Hara, T., Mahadevan, J., Spears, L.D., Oslowski, C.M., Martinez, R., Yamazaki-Inoue, M., Toyoda, M., Neilson, A., Blanner, P., Brown, C.M., Semenkovich, C.F., Marshall, B.A., Hershey, T., Umezawa, A., Greer, P.A., Urano, F., A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome. Proc. Natl. Acad. Sci. USA. 111 (2014), E5292–E5301.
-
(2014)
Proc. Natl. Acad. Sci. USA.
, vol.111
, pp. E5292-E5301
-
-
Lu, S.1
Kanekura, K.2
Hara, T.3
Mahadevan, J.4
Spears, L.D.5
Oslowski, C.M.6
Martinez, R.7
Yamazaki-Inoue, M.8
Toyoda, M.9
Neilson, A.10
Blanner, P.11
Brown, C.M.12
Semenkovich, C.F.13
Marshall, B.A.14
Hershey, T.15
Umezawa, A.16
Greer, P.A.17
Urano, F.18
-
111
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?
-
Malhotra, J.D., Kaufman, R.J., Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword?. Antioxid. Redox Signal 9 (2007), 2277–2293.
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
112
-
-
57449092891
-
Antioxidants reduce endoplasmic reticulum stress and improve protein secretion
-
Malhotra, J.D., Miao, H., Zhang, K., Wolfson, A., Pennathur, S., Pipe, S.W., Kaufman, R.J., Antioxidants reduce endoplasmic reticulum stress and improve protein secretion. Proc. Natl. Acad. Sci. USA. 105 (2008), 18525–18530.
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 18525-18530
-
-
Malhotra, J.D.1
Miao, H.2
Zhang, K.3
Wolfson, A.4
Pennathur, S.5
Pipe, S.W.6
Kaufman, R.J.7
-
113
-
-
77957826835
-
Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery
-
Mao, X.R., Crowder, C.M., Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery. Mol. Cell Biol. 30 (2010), 5033–5042.
-
(2010)
Mol. Cell Biol.
, vol.30
, pp. 5033-5042
-
-
Mao, X.R.1
Crowder, C.M.2
-
114
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak, S.J., Yun, C.Y., Oyadomari, S., Novoa, I., Zhang, Y., Jungreis, R., Nagata, K., Harding, H.P., Ron, D., CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev. 18 (2004), 3066–3077.
-
(2004)
Genes Dev.
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
115
-
-
84881093899
-
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78
-
Martin, S., Lamb, H.K., Brady, C., Lefkove, B., Bonner, M.Y., Thompson, P., Lovat, P.E., Arbiser, J.L., Hawkins, A.R., Redfern, C.P., Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78. Br. J. Cancer 109 (2013), 433–443.
-
(2013)
Br. J. Cancer
, vol.109
, pp. 433-443
-
-
Martin, S.1
Lamb, H.K.2
Brady, C.3
Lefkove, B.4
Bonner, M.Y.5
Thompson, P.6
Lovat, P.E.7
Arbiser, J.L.8
Hawkins, A.R.9
Redfern, C.P.10
-
116
-
-
83755219008
-
Hormesis, cell death and aging
-
Martins, I., Galluzzi, L., Kroemer, G., Hormesis, cell death and aging. Aging 3 (2011), 821–828.
-
(2011)
Aging
, vol.3
, pp. 821-828
-
-
Martins, I.1
Galluzzi, L.2
Kroemer, G.3
-
117
-
-
37749036931
-
Hormesis defined
-
Mattson, M.P., Hormesis defined. Ageing Res. Rev. 7 (2008), 1–7.
-
(2008)
Ageing Res. Rev.
, vol.7
, pp. 1-7
-
-
Mattson, M.P.1
-
118
-
-
73449097110
-
XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy
-
Matus, S., Nassif, M., Glimcher, L.H., Hetz, C., XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy. Autophagy 5 (2009), 1226–1228.
-
(2009)
Autophagy
, vol.5
, pp. 1226-1228
-
-
Matus, S.1
Nassif, M.2
Glimcher, L.H.3
Hetz, C.4
-
119
-
-
84899937866
-
Getting RIDD of RNA: IRE1 in cell fate regulation
-
Maurel, M., Chevet, E., Tavernier, J., Gerlo, S., Getting RIDD of RNA: IRE1 in cell fate regulation. Trends Biochem. Sci. 39 (2014), 245–254.
-
(2014)
Trends Biochem. Sci.
, vol.39
, pp. 245-254
-
-
Maurel, M.1
Chevet, E.2
Tavernier, J.3
Gerlo, S.4
-
120
-
-
33646376225
-
Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons
-
Meller, R., Cameron, J.A., Torrey, D.J., Clayton, C.E., Ordonez, A.N., Henshall, D.C., Minami, M., Schindler, C.K., Saugstad, J.A., Simon, R.P., Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons. J. Biol. Chem. 281 (2006), 7429–7436.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 7429-7436
-
-
Meller, R.1
Cameron, J.A.2
Torrey, D.J.3
Clayton, C.E.4
Ordonez, A.N.5
Henshall, D.C.6
Minami, M.7
Schindler, C.K.8
Saugstad, J.A.9
Simon, R.P.10
-
121
-
-
38149046578
-
Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance
-
Meller, R., Thompson, S.J., Lusardi, T.A., Ordonez, A.N., Ashley, M.D., Jessick, V., Wang, W., Torrey, D.J., Henshall, D.C., Gafken, P.R., Saugstad, J.A., Xiong, Z.G., Simon, R.P., Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance. J. Neurosci. 28 (2008), 50–59.
-
(2008)
J. Neurosci.
, vol.28
, pp. 50-59
-
-
Meller, R.1
Thompson, S.J.2
Lusardi, T.A.3
Ordonez, A.N.4
Ashley, M.D.5
Jessick, V.6
Wang, W.7
Torrey, D.J.8
Henshall, D.C.9
Gafken, P.R.10
Saugstad, J.A.11
Xiong, Z.G.12
Simon, R.P.13
-
122
-
-
65649146419
-
ER stress protects from retinal degeneration
-
Mendes, C.S., Levet, C., Chatelain, G., Dourlen, P., Fouillet, A., Dichtel-Danjoy, M.L., Gambis, A., Ryoo, H.D., Steller, H., Mollereau, B., ER stress protects from retinal degeneration. Embo J. 28 (2009), 1296–1307.
-
(2009)
Embo J.
, vol.28
, pp. 1296-1307
-
-
Mendes, C.S.1
Levet, C.2
Chatelain, G.3
Dourlen, P.4
Fouillet, A.5
Dichtel-Danjoy, M.L.6
Gambis, A.7
Ryoo, H.D.8
Steller, H.9
Mollereau, B.10
-
123
-
-
84875259777
-
An ERcentric view of Parkinson׳s disease
-
Mercado, G., Valdes, P., Hetz, C., An ERcentric view of Parkinson׳s disease. Trends Mol. Med. 19 (2013), 165–175.
-
(2013)
Trends Mol. Med.
, vol.19
, pp. 165-175
-
-
Mercado, G.1
Valdes, P.2
Hetz, C.3
-
124
-
-
84926343690
-
ER proteostasis disturbances in Parkinson׳s disease: novel insights
-
Mercado, G., Castillo, V., Vidal, R., Hetz, C., ER proteostasis disturbances in Parkinson׳s disease: novel insights. Front. Aging Neurosci., 7, 2015, 39.
-
(2015)
Front. Aging Neurosci.
, vol.7
, pp. 39
-
-
Mercado, G.1
Castillo, V.2
Vidal, R.3
Hetz, C.4
-
125
-
-
14644422198
-
Photoreceptor differentiation in Drosophila: from immature neurons to functional photoreceptors
-
Mollereau, B., Domingos, P.M., Photoreceptor differentiation in Drosophila: from immature neurons to functional photoreceptors. Dev. Dyn. 232 (2005), 585–592.
-
(2005)
Dev. Dyn.
, vol.232
, pp. 585-592
-
-
Mollereau, B.1
Domingos, P.M.2
-
126
-
-
68149132463
-
Cell death: what can we learn from flies? Editorial for the special review issue on Drosophila apoptosis
-
Mollereau, B., Cell death: what can we learn from flies? Editorial for the special review issue on Drosophila apoptosis. Apoptosis 14 (2009), 929–934.
-
(2009)
Apoptosis
, vol.14
, pp. 929-934
-
-
Mollereau, B.1
-
127
-
-
84878980614
-
Establishing links between ER-hormesis and cancer
-
Mollereau, B., Establishing links between ER-hormesis and cancer. Mol. Cell Biol. 33 (2013), 2372–2374.
-
(2013)
Mol. Cell Biol.
, vol.33
, pp. 2372-2374
-
-
Mollereau, B.1
-
128
-
-
84919883633
-
Getting the better of ER stress
-
Mollereau, B., Manie, S., Napoletano, F., Getting the better of ER stress. J. Cell. Commun. Signal 8 (2014), 311–321.
-
(2014)
J. Cell. Commun. Signal
, vol.8
, pp. 311-321
-
-
Mollereau, B.1
Manie, S.2
Napoletano, F.3
-
129
-
-
84949623325
-
Cooling-induced ER stress is good for your brain
-
Mollereau, B., Cooling-induced ER stress is good for your brain. EBioMedicine 2 (2015), 482–483.
-
(2015)
EBioMedicine
, vol.2
, pp. 482-483
-
-
Mollereau, B.1
-
130
-
-
84861450392
-
Sustained translational repression by eIF2alpha-P mediates prion neurodegeneration
-
Moreno, J.A., Radford, H., Peretti, D., Steinert, J.R., Verity, N., Martin, M.G., Halliday, M., Morgan, J., Dinsdale, D., Ortori, C.A., Barrett, D.A., Tsaytler, P., Bertolotti, A., Willis, A.E., Bushell, M., Mallucci, G.R., Sustained translational repression by eIF2alpha-P mediates prion neurodegeneration. Nature 485 (2012), 507–511.
-
(2012)
Nature
, vol.485
, pp. 507-511
-
-
Moreno, J.A.1
Radford, H.2
Peretti, D.3
Steinert, J.R.4
Verity, N.5
Martin, M.G.6
Halliday, M.7
Morgan, J.8
Dinsdale, D.9
Ortori, C.A.10
Barrett, D.A.11
Tsaytler, P.12
Bertolotti, A.13
Willis, A.E.14
Bushell, M.15
Mallucci, G.R.16
-
131
-
-
0031297298
-
The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones
-
Morimoto, R.I., Kline, M.P., Bimston, D.N., Cotto, J.J., The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones. Essays Biochem. 32 (1997), 17–29.
-
(1997)
Essays Biochem.
, vol.32
, pp. 17-29
-
-
Morimoto, R.I.1
Kline, M.P.2
Bimston, D.N.3
Cotto, J.J.4
-
132
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
Morimoto, R.I., Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev. 22 (2008), 1427–1438.
-
(2008)
Genes Dev.
, vol.22
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
133
-
-
84960147624
-
Cerebral ischemic preconditioning: the road so far
-
Epub ahead of print
-
N, T.V., Sangwan, A., Sharma, B., Majid, A., Gk, R., Cerebral ischemic preconditioning: the road so far. Mol. Neurobiol., 2015 Epub ahead of print.
-
(2015)
Mol. Neurobiol.
-
-
Sangwan, A.1
Sharma, B.2
Majid, A.3
Gk, R.4
-
134
-
-
77449095179
-
Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats
-
Nakka, V.P., Gusain, A., Raghubir, R., Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/reperfusion in rats. Neurotox. Res. 17 (2010), 189–202.
-
(2010)
Neurotox. Res.
, vol.17
, pp. 189-202
-
-
Nakka, V.P.1
Gusain, A.2
Raghubir, R.3
-
135
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra, D., Tanaka, A., Suen, D.F., Youle, R.J., Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell. Biol. 183 (2008), 795–803.
-
(2008)
J. Cell. Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
136
-
-
0034746189
-
The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling
-
Nicole, O., Docagne, F., Ali, C., Margaill, I., Carmeliet, P., MacKenzie, E.T., Vivien, D., Buisson, A., The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nat. Med. 7 (2001), 59–64.
-
(2001)
Nat. Med.
, vol.7
, pp. 59-64
-
-
Nicole, O.1
Docagne, F.2
Ali, C.3
Margaill, I.4
Carmeliet, P.5
MacKenzie, E.T.6
Vivien, D.7
Buisson, A.8
-
137
-
-
0028783948
-
Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
-
NINDS, Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N. Engl. J. Med. 333 (1995), 1581–1587.
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1581-1587
-
-
NINDS1
-
138
-
-
44849124411
-
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
-
Nishitoh, H., Kadowaki, H., Nagai, A., Maruyama, T., Yokota, T., Fukutomi, H., Noguchi, T., Matsuzawa, A., Takeda, K., Ichijo, H., ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1. Genes Dev. 22 (2008), 1451–1464.
-
(2008)
Genes Dev.
, vol.22
, pp. 1451-1464
-
-
Nishitoh, H.1
Kadowaki, H.2
Nagai, A.3
Maruyama, T.4
Yokota, T.5
Fukutomi, H.6
Noguchi, T.7
Matsuzawa, A.8
Takeda, K.9
Ichijo, H.10
-
139
-
-
77953391745
-
Rapid ischemic tolerance induced by adenosine preconditioning results in Bcl-2 interacting mediator of cell death (Bim) degradation by the proteasome
-
Ordonez, A.N., Jessick, V.J., Clayton, C.E., Ashley, M.D., Thompson, S.J., Simon, R.P., Meller, R., Rapid ischemic tolerance induced by adenosine preconditioning results in Bcl-2 interacting mediator of cell death (Bim) degradation by the proteasome. Int. J. Physiol. Pathophysiol. Pharmacol. 2 (2010), 36–44.
-
(2010)
Int. J. Physiol. Pathophysiol. Pharmacol.
, vol.2
, pp. 36-44
-
-
Ordonez, A.N.1
Jessick, V.J.2
Clayton, C.E.3
Ashley, M.D.4
Thompson, S.J.5
Simon, R.P.6
Meller, R.7
-
140
-
-
77953539363
-
Characterization of neuronal and astroglial responses to ER stress in the hippocampal CA1 area in mice following transient forebrain ischemia
-
Osada, N., Kosuge, Y., Ishige, K., Ito, Y., Characterization of neuronal and astroglial responses to ER stress in the hippocampal CA1 area in mice following transient forebrain ischemia. Neurochem. Int. 57 (2010), 1–7.
-
(2010)
Neurochem. Int.
, vol.57
, pp. 1-7
-
-
Osada, N.1
Kosuge, Y.2
Ishige, K.3
Ito, Y.4
-
141
-
-
5644251587
-
Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity
-
Pang, P.T., Teng, H.K., Zaitsev, E., Woo, N.T., Sakata, K., Zhen, S., Teng, K.K., Yung, W.H., Hempstead, B.L., Lu, B., Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 306 (2004), 487–491.
-
(2004)
Science
, vol.306
, pp. 487-491
-
-
Pang, P.T.1
Teng, H.K.2
Zaitsev, E.3
Woo, N.T.4
Sakata, K.5
Zhen, S.6
Teng, K.K.7
Yung, W.H.8
Hempstead, B.L.9
Lu, B.10
-
143
-
-
0033542745
-
Global ischemia-induced inhibition of the coupling ratio of calcium uptake and ATP hydrolysis by rat whole brain microsomal Mg(2+)/Ca(2+) ATPase
-
Parsons, J.T., Churn, S.B., DeLorenzo, R.J., Global ischemia-induced inhibition of the coupling ratio of calcium uptake and ATP hydrolysis by rat whole brain microsomal Mg(2+)/Ca(2+) ATPase. Brain Res. 834 (1999), 32–41.
-
(1999)
Brain Res.
, vol.834
, pp. 32-41
-
-
Parsons, J.T.1
Churn, S.B.2
DeLorenzo, R.J.3
-
144
-
-
0032544514
-
Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction
-
Paschen, W., Gissel, C., Linden, T., Althausen, S., Doutheil, J., Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction. Brain Res. Mol. Brain Res. 60 (1998), 115–122.
-
(1998)
Brain Res. Mol. Brain Res.
, vol.60
, pp. 115-122
-
-
Paschen, W.1
Gissel, C.2
Linden, T.3
Althausen, S.4
Doutheil, J.5
-
145
-
-
0043037253
-
Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain
-
Paschen, W., Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell. Calcium 34 (2003), 365–383.
-
(2003)
Cell. Calcium
, vol.34
, pp. 365-383
-
-
Paschen, W.1
-
146
-
-
0037385160
-
Transient cerebral ischemia activates processing of xbp1 messenger RNA indicative of endoplasmic reticulum stress
-
Paschen, W., Aufenberg, C., Hotop, S., Mengesdorf, T., Transient cerebral ischemia activates processing of xbp1 messenger RNA indicative of endoplasmic reticulum stress. J. Cereb. Blood Flow Metab. 23 (2003), 449–461.
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 449-461
-
-
Paschen, W.1
Aufenberg, C.2
Hotop, S.3
Mengesdorf, T.4
-
147
-
-
4243621209
-
Calcium and increase excitability promote tolerance against anoxia in hippocampal slices
-
Perez-Pinzon, M.A., Born, J.G., Centeno, J.M., Calcium and increase excitability promote tolerance against anoxia in hippocampal slices. Brain Res. 833 (1999), 20–26.
-
(1999)
Brain Res.
, vol.833
, pp. 20-26
-
-
Perez-Pinzon, M.A.1
Born, J.G.2
Centeno, J.M.3
-
148
-
-
84963673231
-
The unfolded protein response and the role of protein disulfide isomerase in neurodegeneration
-
Perri, E.R., Thomas, C.J., Parakh, S., Spencer, D.M., Atkin, J.D., The unfolded protein response and the role of protein disulfide isomerase in neurodegeneration. Front. Cell. Dev. Biol., 3, 2015, 80.
-
(2015)
Front. Cell. Dev. Biol.
, vol.3
, pp. 80
-
-
Perri, E.R.1
Thomas, C.J.2
Parakh, S.3
Spencer, D.M.4
Atkin, J.D.5
-
149
-
-
0033918122
-
Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia
-
Phillips, J.B., Williams, A.J., Adams, J., Elliott, P.J., Tortella, F.C., Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia. Stroke 31 (2000), 1686–1693.
-
(2000)
Stroke
, vol.31
, pp. 1686-1693
-
-
Phillips, J.B.1
Williams, A.J.2
Adams, J.3
Elliott, P.J.4
Tortella, F.C.5
-
150
-
-
84881436099
-
Posttranscriptional regulation of PER1 underlies the oncogenic function of IREalpha
-
Pluquet, O., Dejeans, N., Bouchecareilh, M., Lhomond, S., Pineau, R., Higa, A., Delugin, M., Combe, C., Loriot, S., Cubel, G., Dugot-Senant, N., Vital, A., Loiseau, H., Gosline, S.J., Taouji, S., Hallett, M., Sarkaria, J.N., Anderson, K., Wu, W., Rodriguez, F.J., Rosenbaum, J., Saltel, F., Fernandez-Zapico, M.E., Chevet, E., Posttranscriptional regulation of PER1 underlies the oncogenic function of IREalpha. Cancer Res. 73 (2013), 4732–4743.
-
(2013)
Cancer Res.
, vol.73
, pp. 4732-4743
-
-
Pluquet, O.1
Dejeans, N.2
Bouchecareilh, M.3
Lhomond, S.4
Pineau, R.5
Higa, A.6
Delugin, M.7
Combe, C.8
Loriot, S.9
Cubel, G.10
Dugot-Senant, N.11
Vital, A.12
Loiseau, H.13
Gosline, S.J.14
Taouji, S.15
Hallett, M.16
Sarkaria, J.N.17
Anderson, K.18
Wu, W.19
Rodriguez, F.J.20
Rosenbaum, J.21
Saltel, F.22
Fernandez-Zapico, M.E.23
Chevet, E.24
more..
-
151
-
-
84871414195
-
Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA
-
Prabhu, A., Sarcar, B., Kahali, S., Shan, Y., Chinnaiyan, P., Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA. Plos One, 7, 2012, e52265.
-
(2012)
Plos One
, vol.7
, pp. e52265
-
-
Prabhu, A.1
Sarcar, B.2
Kahali, S.3
Shan, Y.4
Chinnaiyan, P.5
-
152
-
-
35448967382
-
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
-
Pyrko, P., Schonthal, A.H., Hofman, F.M., Chen, T.C., Lee, A.S., The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res. 67 (2007), 9809–9816.
-
(2007)
Cancer Res.
, vol.67
, pp. 9809-9816
-
-
Pyrko, P.1
Schonthal, A.H.2
Hofman, F.M.3
Chen, T.C.4
Lee, A.S.5
-
153
-
-
84939857322
-
Nicotine and nicotinic receptor drugs: potential for Parkinson׳s disease and drug-induced movement disorders
-
Quik, M., Bordia, T., Zhang, D., Perez, X.A., Nicotine and nicotinic receptor drugs: potential for Parkinson׳s disease and drug-induced movement disorders. Int. Rev. Neurobiol. 124 (2015), 247–271.
-
(2015)
Int. Rev. Neurobiol.
, vol.124
, pp. 247-271
-
-
Quik, M.1
Bordia, T.2
Zhang, D.3
Perez, X.A.4
-
154
-
-
68149136657
-
Cellular responses to endoplasmic reticulum stress and apoptosis
-
Rasheva, V.I., Domingos, P.M., Cellular responses to endoplasmic reticulum stress and apoptosis. Apoptosis 14 (2009), 996–1007.
-
(2009)
Apoptosis
, vol.14
, pp. 996-1007
-
-
Rasheva, V.I.1
Domingos, P.M.2
-
155
-
-
33646860572
-
Prolonged bihemispheric alterations in unfolded protein response related gene expression after experimental stroke
-
Rissanen, A., Sivenius, J., Jolkkonen, J., Prolonged bihemispheric alterations in unfolded protein response related gene expression after experimental stroke. Brain Res. 1087 (2006), 60–66.
-
(2006)
Brain Res.
, vol.1087
, pp. 60-66
-
-
Rissanen, A.1
Sivenius, J.2
Jolkkonen, J.3
-
156
-
-
34447255185
-
Pooled analysis of tobacco use and risk of Parkinson disease
-
Ritz, B., Ascherio, A., Checkoway, H., Marder, K.S., Nelson, L.M., Rocca, W.A., Ross, G.W., Strickland, D., Van Den Eeden, S.K., Gorell, J., Pooled analysis of tobacco use and risk of Parkinson disease. Arch. Neurol. 64 (2007), 990–997.
-
(2007)
Arch. Neurol.
, vol.64
, pp. 990-997
-
-
Ritz, B.1
Ascherio, A.2
Checkoway, H.3
Marder, K.S.4
Nelson, L.M.5
Rocca, W.A.6
Ross, G.W.7
Strickland, D.8
Van Den Eeden, S.K.9
Gorell, J.10
-
157
-
-
34247239755
-
Hippocampal cellular stress responses after global brain ischemia and reperfusion
-
Roberts, G.G., Di Loreto, M.J., Marshall, M., Wang, J., DeGracia, D.J., Hippocampal cellular stress responses after global brain ischemia and reperfusion. Antioxid. Redox Signal 9 (2007), 2265–2275.
-
(2007)
Antioxid. Redox Signal
, vol.9
, pp. 2265-2275
-
-
Roberts, G.G.1
Di Loreto, M.J.2
Marshall, M.3
Wang, J.4
DeGracia, D.J.5
-
158
-
-
0034688312
-
Glutamate release in severe brain ischaemia is mainly by reversed uptake
-
Rossi, D.J., Oshima, T., Attwell, D., Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 403 (2000), 316–321.
-
(2000)
Nature
, vol.403
, pp. 316-321
-
-
Rossi, D.J.1
Oshima, T.2
Attwell, D.3
-
159
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
Rubinsztein, D.C., The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443 (2006), 780–786.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
160
-
-
33751069967
-
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
-
Rutkowski, D.T., Arnold, S.M., Miller, C.N., Wu, J., Li, J., Gunnison, K.M., Mori, K., Sadighi Akha, A.A., Raden, D., Kaufman, R.J., Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. Plos. Biol., 4, 2006, e374.
-
(2006)
Plos. Biol.
, vol.4
, pp. e374
-
-
Rutkowski, D.T.1
Arnold, S.M.2
Miller, C.N.3
Wu, J.4
Li, J.5
Gunnison, K.M.6
Mori, K.7
Sadighi Akha, A.A.8
Raden, D.9
Kaufman, R.J.10
-
161
-
-
84946556838
-
Current insights into the molecular mechanisms of hypoxic pre- and postconditioning using hypobaric hypoxia
-
Rybnikova, E., Samoilov, M., Current insights into the molecular mechanisms of hypoxic pre- and postconditioning using hypobaric hypoxia. Front. Neurosci., 9, 2015, 388.
-
(2015)
Front. Neurosci.
, vol.9
, pp. 388
-
-
Rybnikova, E.1
Samoilov, M.2
-
162
-
-
33846219134
-
Unfolded protein response in a Drosophila model for retinal degeneration
-
Ryoo, H.D., Domingos, P.M., Kang, M.J., Steller, H., Unfolded protein response in a Drosophila model for retinal degeneration. Embo J. 26 (2007), 242–252.
-
(2007)
Embo J.
, vol.26
, pp. 242-252
-
-
Ryoo, H.D.1
Domingos, P.M.2
Kang, M.J.3
Steller, H.4
-
163
-
-
34147142514
-
Unfolded protein response in Drosophila: why another model can make it fly
-
Ryoo, H.D., Steller, H., Unfolded protein response in Drosophila: why another model can make it fly. Cell Cycle 6 (2007), 830–835.
-
(2007)
Cell Cycle
, vol.6
, pp. 830-835
-
-
Ryoo, H.D.1
Steller, H.2
-
164
-
-
84944750747
-
Drosophila as a model for unfolded protein response research
-
Ryoo, H.D., Drosophila as a model for unfolded protein response research. BMB Rep. 48 (2015), 445–453.
-
(2015)
BMB Rep.
, vol.48
, pp. 445-453
-
-
Ryoo, H.D.1
-
165
-
-
84949548693
-
Hypothermic preconditioning of human cortical neurons requires proteostatic priming
-
Rzechorzek, N.M., Connick, P., Patani, R., Selvaraj, B.T., Chandran, S., Hypothermic preconditioning of human cortical neurons requires proteostatic priming. EBioMedicine 2 (2015), 528–535.
-
(2015)
EBioMedicine
, vol.2
, pp. 528-535
-
-
Rzechorzek, N.M.1
Connick, P.2
Patani, R.3
Selvaraj, B.T.4
Chandran, S.5
-
166
-
-
84958946375
-
Hypothermic preconditioning reverses tau ontogenesis in human cortical neurons and is mimicked by protein phosphatase 2A inhibition
-
Rzechorzek, N.M., Connick, P., Livesey, M.R., Borooah, S., Patani, R., Burr, K., Story, D., Wyllie, D.J.A., Hardingham, G.E., Chandran, S., Hypothermic preconditioning reverses tau ontogenesis in human cortical neurons and is mimicked by protein phosphatase 2A inhibition. EBioMedicine 3 (2016), 141–154.
-
(2016)
EBioMedicine
, vol.3
, pp. 141-154
-
-
Rzechorzek, N.M.1
Connick, P.2
Livesey, M.R.3
Borooah, S.4
Patani, R.5
Burr, K.6
Story, D.7
Wyllie, D.J.A.8
Hardingham, G.E.9
Chandran, S.10
-
167
-
-
84901608833
-
Fine tuning of the UPR by the ubiquitin ligases Siah1/2
-
Scortegagna, M., Kim, H., Li, J.L., Yao, H., Brill, L.M., Han, J., Lau, E., Bowtell, D., Haddad, G., Kaufman, R.J., Ronai, Z.A., Fine tuning of the UPR by the ubiquitin ligases Siah1/2. Plos. Genet., 10, 2014, e1004348.
-
(2014)
Plos. Genet.
, vol.10
, pp. e1004348
-
-
Scortegagna, M.1
Kim, H.2
Li, J.L.3
Yao, H.4
Brill, L.M.5
Han, J.6
Lau, E.7
Bowtell, D.8
Haddad, G.9
Kaufman, R.J.10
Ronai, Z.A.11
-
168
-
-
35148888161
-
Life with oxygen
-
Semenza, G.L., Life with oxygen. Science. 318 (2007), 62–64.
-
(2007)
Science.
, vol.318
, pp. 62-64
-
-
Semenza, G.L.1
-
169
-
-
84859118387
-
Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning
-
Sheng, R., Liu, X.Q., Zhang, L.S., Gao, B., Han, R., Wu, Y.Q., Zhang, X.Y., Qin, Z.H., Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning. Autophagy 8 (2012), 310–325.
-
(2012)
Autophagy
, vol.8
, pp. 310-325
-
-
Sheng, R.1
Liu, X.Q.2
Zhang, L.S.3
Gao, B.4
Han, R.5
Wu, Y.Q.6
Zhang, X.Y.7
Qin, Z.H.8
-
170
-
-
84926331325
-
The divergent roles of autophagy in ischemia and preconditioning
-
Sheng, R., Qin, Z.H., The divergent roles of autophagy in ischemia and preconditioning. Acta Pharmacol. Sin. 36 (2015), 411–420.
-
(2015)
Acta Pharmacol. Sin.
, vol.36
, pp. 411-420
-
-
Sheng, R.1
Qin, Z.H.2
-
171
-
-
47249147487
-
Preconditioning paradigms and pathways in the brain
-
Shpargel, K.B., Jalabi, W., Jin, Y., Dadabayev, A., Penn, M.S., Trapp, B.D., Preconditioning paradigms and pathways in the brain. Cleve Clin. J. Med. 75:Suppl. 2 (2008), S77–S82.
-
(2008)
Cleve Clin. J. Med.
, vol.75
, pp. S77-S82
-
-
Shpargel, K.B.1
Jalabi, W.2
Jin, Y.3
Dadabayev, A.4
Penn, M.S.5
Trapp, B.D.6
-
172
-
-
84947232386
-
Borrelidin induces the unfolded protein response in oral cancer cells and chop-dependent apoptosis
-
Sidhu, A., Miller, J.R., Tripathi, A., Garshott, D.M., Brownell, A.L., Chiego, D.J., Arevang, C., Zeng, Q., Jackson, L.C., Bechler, S.A., Callaghan, M.U., Yoo, G.H., Sethi, S., Lin, H.S., Callaghan, J.H., Tamayo-Castillo, G., Sherman, D.H., Kaufman, R.J., Fribley, A.M., Borrelidin induces the unfolded protein response in oral cancer cells and chop-dependent apoptosis. ACS Med. Chem. Lett. 6 (2015), 1122–1127.
-
(2015)
ACS Med. Chem. Lett.
, vol.6
, pp. 1122-1127
-
-
Sidhu, A.1
Miller, J.R.2
Tripathi, A.3
Garshott, D.M.4
Brownell, A.L.5
Chiego, D.J.6
Arevang, C.7
Zeng, Q.8
Jackson, L.C.9
Bechler, S.A.10
Callaghan, M.U.11
Yoo, G.H.12
Sethi, S.13
Lin, H.S.14
Callaghan, J.H.15
Tamayo-Castillo, G.16
Sherman, D.H.17
Kaufman, R.J.18
Fribley, A.M.19
-
173
-
-
28244466782
-
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
-
Silva, R.M., Ries, V., Oo, T.F., Yarygina, O., Jackson-Lewis, V., Ryu, E.J., Lu, P.D., Marciniak, S.J., Ron, D., Przedborski, S., Kholodilov, N., Greene, L.A., Burke, R.E., CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. J. Neurochem. 95 (2005), 974–986.
-
(2005)
J. Neurochem.
, vol.95
, pp. 974-986
-
-
Silva, R.M.1
Ries, V.2
Oo, T.F.3
Yarygina, O.4
Jackson-Lewis, V.5
Ryu, E.J.6
Lu, P.D.7
Marciniak, S.J.8
Ron, D.9
Przedborski, S.10
Kholodilov, N.11
Greene, L.A.12
Burke, R.E.13
-
174
-
-
55849096988
-
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
-
Song, B., Scheuner, D., Ron, D., Pennathur, S., Kaufman, R.J., Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J. Clin. Invest. 118 (2008), 3378–3389.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3378-3389
-
-
Song, B.1
Scheuner, D.2
Ron, D.3
Pennathur, S.4
Kaufman, R.J.5
-
175
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto, C., Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci. 4 (2003), 49–60.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
176
-
-
84953807198
-
Smoking-relevant nicotine concentration attenuates the unfolded protein response in dopaminergic neurons
-
Srinivasan, R., Henley, B.M., Henderson, B.J., Indersmitten, T., Cohen, B.N., Kim, C.H., McKinney, S., Deshpande, P., Xiao, C., Lester, H.A., Smoking-relevant nicotine concentration attenuates the unfolded protein response in dopaminergic neurons. J. Neurosci. 36 (2016), 65–79.
-
(2016)
J. Neurosci.
, vol.36
, pp. 65-79
-
-
Srinivasan, R.1
Henley, B.M.2
Henderson, B.J.3
Indersmitten, T.4
Cohen, B.N.5
Kim, C.H.6
McKinney, S.7
Deshpande, P.8
Xiao, C.9
Lester, H.A.10
-
177
-
-
84896400147
-
Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance
-
Stetler, R.A., Leak, R.K., Gan, Y., Li, P., Zhang, F., Hu, X., Jing, Z., Chen, J., Zigmond, M.J., Gao, Y., Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance. Prog. Neurobiol. 114 (2014), 58–83.
-
(2014)
Prog. Neurobiol.
, vol.114
, pp. 58-83
-
-
Stetler, R.A.1
Leak, R.K.2
Gan, Y.3
Li, P.4
Zhang, F.5
Hu, X.6
Jing, Z.7
Chen, J.8
Zigmond, M.J.9
Gao, Y.10
-
178
-
-
84982280683
-
Endoplasmic reticulum stress in brain ischemia
-
Su, Y., Li, F., Endoplasmic reticulum stress in brain ischemia. Int. J. Neurosci., 2015, 1–11.
-
(2015)
Int. J. Neurosci.
, pp. 1-11
-
-
Su, Y.1
Li, F.2
-
179
-
-
84873287971
-
ATF4 protects against neuronal death in cellular Parkinson׳s disease models by maintaining levels of parkin
-
Sun, X., Liu, J., Crary, J.F., Malagelada, C., Sulzer, D., Greene, L.A., Levy, O.A., ATF4 protects against neuronal death in cellular Parkinson׳s disease models by maintaining levels of parkin. J. Neurosci. 33 (2013), 2398–2407.
-
(2013)
J. Neurosci.
, vol.33
, pp. 2398-2407
-
-
Sun, X.1
Liu, J.2
Crary, J.F.3
Malagelada, C.4
Sulzer, D.5
Greene, L.A.6
Levy, O.A.7
-
180
-
-
84866478442
-
The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin–proteasome system
-
Tai, H.C., Serrano-Pozo, A., Hashimoto, T., Frosch, M.P., Spires-Jones, T.L., Hyman, B.T., The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin–proteasome system. Am. J. Pathol. 181 (2012), 1426–1435.
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 1426-1435
-
-
Tai, H.C.1
Serrano-Pozo, A.2
Hashimoto, T.3
Frosch, M.P.4
Spires-Jones, T.L.5
Hyman, B.T.6
-
181
-
-
1842854719
-
Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP
-
Tajiri, S., Oyadomari, S., Yano, S., Morioka, M., Gotoh, T., Hamada, J.I., Ushio, Y., Mori, M., Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP. Cell. Death Differ. 11 (2004), 403–415.
-
(2004)
Cell. Death Differ.
, vol.11
, pp. 403-415
-
-
Tajiri, S.1
Oyadomari, S.2
Yano, S.3
Morioka, M.4
Gotoh, T.5
Hamada, J.I.6
Ushio, Y.7
Mori, M.8
-
182
-
-
0034640520
-
Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis
-
Tanahashi, N., Murakami, Y., Minami, Y., Shimbara, N., Hendil, K.B., Tanaka, K., Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis. J. Biol. Chem. 275 (2000), 14336–14345.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14336-14345
-
-
Tanahashi, N.1
Murakami, Y.2
Minami, Y.3
Shimbara, N.4
Hendil, K.B.5
Tanaka, K.6
-
183
-
-
58149168845
-
Subcellular stress response and induction of molecular chaperones and folding proteins after transient global ischemia in rats
-
Truettner, J.S., Hu, K., Liu, C.L., Dietrich, W.D., Hu, B., Subcellular stress response and induction of molecular chaperones and folding proteins after transient global ischemia in rats. Brain Res. 1249 (2009), 9–18.
-
(2009)
Brain Res.
, vol.1249
, pp. 9-18
-
-
Truettner, J.S.1
Hu, K.2
Liu, C.L.3
Dietrich, W.D.4
Hu, B.5
-
184
-
-
84940094379
-
Modulation of endoplasmic reticulum stress in Parkinson׳s disease
-
Tsujii, S., Ishisaka, M., Hara, H., Modulation of endoplasmic reticulum stress in Parkinson׳s disease. Eur. J. Pharmacol. 765 (2015), 154–156.
-
(2015)
Eur. J. Pharmacol.
, vol.765
, pp. 154-156
-
-
Tsujii, S.1
Ishisaka, M.2
Hara, H.3
-
185
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano, F., Wang, X., Bertolotti, A., Zhang, Y., Chung, P., Harding, H.P., Ron, D., Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287 (2000), 664–666.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
186
-
-
84953390394
-
Wolfram syndrome: diagnosis, management, and treatment
-
Urano, F., Wolfram syndrome: diagnosis, management, and treatment. Curr. Diab. Rep., 16, 2016, 6.
-
(2016)
Curr. Diab. Rep.
, vol.16
, pp. 6
-
-
Urano, F.1
-
187
-
-
84899844505
-
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
-
Valdes, P., Mercado, G., Vidal, R.L., Molina, C., Parsons, G., Court, F.A., Martinez, A., Galleguillos, D., Armentano, D., Schneider, B.L., Hetz, C., Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1. Proc. Natl. Acad. Sci. USA. 111 (2014), 6804–6809.
-
(2014)
Proc. Natl. Acad. Sci. USA.
, vol.111
, pp. 6804-6809
-
-
Valdes, P.1
Mercado, G.2
Vidal, R.L.3
Molina, C.4
Parsons, G.5
Court, F.A.6
Martinez, A.7
Galleguillos, D.8
Armentano, D.9
Schneider, B.L.10
Hetz, C.11
-
188
-
-
84860471873
-
Targeting the UPR transcription factor XBP1 protects against Huntington׳s disease through the regulation of FoxO1 and autophagy
-
Vidal, R.L., Figueroa, A., Court, F.A., Thielen, P., Molina, C., Wirth, C., Caballero, B., Kiffin, R., Segura-Aguilar, J., Cuervo, A.M., Glimcher, L.H., Hetz, C., Targeting the UPR transcription factor XBP1 protects against Huntington׳s disease through the regulation of FoxO1 and autophagy. Hum. Mol. Genet. 21 (2012), 2245–2262.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2245-2262
-
-
Vidal, R.L.1
Figueroa, A.2
Court, F.A.3
Thielen, P.4
Molina, C.5
Wirth, C.6
Caballero, B.7
Kiffin, R.8
Segura-Aguilar, J.9
Cuervo, A.M.10
Glimcher, L.H.11
Hetz, C.12
-
189
-
-
84948674540
-
Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson׳s disease
-
Voutilainen, M.H., Arumae, U., Airavaara, M., Saarma, M., Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson׳s disease. FEBS Lett. 589 (2015), 3739–3748.
-
(2015)
FEBS Lett.
, vol.589
, pp. 3739-3748
-
-
Voutilainen, M.H.1
Arumae, U.2
Airavaara, M.3
Saarma, M.4
-
190
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter, P., Ron, D., The unfolded protein response: from stress pathway to homeostatic regulation. Science 334 (2011), 1081–1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
191
-
-
84955445779
-
Protein misfolding in the endoplasmic reticulum as a conduit to human disease
-
Wang, M., Kaufman, R.J., Protein misfolding in the endoplasmic reticulum as a conduit to human disease. Nature 529 (2016), 326–335.
-
(2016)
Nature
, vol.529
, pp. 326-335
-
-
Wang, M.1
Kaufman, R.J.2
-
192
-
-
84863740827
-
The impact of the unfolded protein response on human disease
-
Wang, S., Kaufman, R.J., The impact of the unfolded protein response on human disease. J. Cell Biol. 197 (2012), 857–867.
-
(2012)
J. Cell Biol.
, vol.197
, pp. 857-867
-
-
Wang, S.1
Kaufman, R.J.2
-
193
-
-
79960890578
-
A role for tumor necrosis factor-alpha in ischemia and ischemic preconditioning
-
Watters, O., O׳Connor, J.J., A role for tumor necrosis factor-alpha in ischemia and ischemic preconditioning. J. Neuroinflamm., 8, 2011, 87.
-
(2011)
J. Neuroinflamm.
, vol.8
, pp. 87
-
-
Watters, O.1
O׳Connor, J.J.2
-
194
-
-
0037215550
-
Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration
-
Williams, A.J., Hale, S.L., Moffett, J.R., Dave, J.R., Elliott, P.J., Adams, J., Tortella, F.C., Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration. J. Cereb. Blood Flow Metab. 23 (2003), 75–87.
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 75-87
-
-
Williams, A.J.1
Hale, S.L.2
Moffett, J.R.3
Dave, J.R.4
Elliott, P.J.5
Adams, J.6
Tortella, F.C.7
-
195
-
-
2142766831
-
Delayed treatment of ischemia/reperfusion brain injury: extended therapeutic window with the proteosome inhibitor MLN519
-
Williams, A.J., Berti, R., Dave, J.R., Elliot, P.J., Adams, J., Tortella, F.C., Delayed treatment of ischemia/reperfusion brain injury: extended therapeutic window with the proteosome inhibitor MLN519. Stroke 35 (2004), 1186–1191.
-
(2004)
Stroke
, vol.35
, pp. 1186-1191
-
-
Williams, A.J.1
Berti, R.2
Dave, J.R.3
Elliot, P.J.4
Adams, J.5
Tortella, F.C.6
-
196
-
-
19344377483
-
Recovery from ischemic brain injury in the rat following a 10 h delayed injection with MLN519
-
Williams, A.J., Myers, T.M., Cohn, S.I., Sharrow, K.M., Lu, X.C., Tortella, F.C., Recovery from ischemic brain injury in the rat following a 10 h delayed injection with MLN519. Pharmacol. Biochem. Behav. 81 (2005), 182–189.
-
(2005)
Pharmacol. Biochem. Behav.
, vol.81
, pp. 182-189
-
-
Williams, A.J.1
Myers, T.M.2
Cohn, S.I.3
Sharrow, K.M.4
Lu, X.C.5
Tortella, F.C.6
-
197
-
-
84856487878
-
Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B
-
Woo, C.W., Kutzler, L., Kimball, S.R., Tabas, I., Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B. Nat. Cell Biol. 14 (2012), 192–200.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 192-200
-
-
Woo, C.W.1
Kutzler, L.2
Kimball, S.R.3
Tabas, I.4
-
198
-
-
34548189283
-
ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress
-
Wu, J., Rutkowski, D.T., Dubois, M., Swathirajan, J., Saunders, T., Wang, J., Song, B., Yau, G.D., Kaufman, R.J., ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress. Dev. Cell. 13 (2007), 351–364.
-
(2007)
Dev. Cell.
, vol.13
, pp. 351-364
-
-
Wu, J.1
Rutkowski, D.T.2
Dubois, M.3
Swathirajan, J.4
Saunders, T.5
Wang, J.6
Song, B.7
Yau, G.D.8
Kaufman, R.J.9
-
199
-
-
84880134855
-
Inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of candesartan cilexitil in the rotenone rat model of Parkinson׳s disease
-
Wu, L., Tian, Y.Y., Shi, J.P., Xie, W., Shi, J.Q., Lu, J., Zhang, Y.D., Inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of candesartan cilexitil in the rotenone rat model of Parkinson׳s disease. Neurosci. Lett. 548 (2013), 50–55.
-
(2013)
Neurosci. Lett.
, vol.548
, pp. 50-55
-
-
Wu, L.1
Tian, Y.Y.2
Shi, J.P.3
Xie, W.4
Shi, J.Q.5
Lu, J.6
Zhang, Y.D.7
-
200
-
-
76249095217
-
PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells
-
Yacoub, A., Hamed, H.A., Allegood, J., Mitchell, C., Spiegel, S., Lesniak, M.S., Ogretmen, B., Dash, R., Sarkar, D., Broaddus, W.C., Grant, S., Curiel, D.T., Fisher, P.B., Dent, P., PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Res. 70 (2010), 1120–1129.
-
(2010)
Cancer Res.
, vol.70
, pp. 1120-1129
-
-
Yacoub, A.1
Hamed, H.A.2
Allegood, J.3
Mitchell, C.4
Spiegel, S.5
Lesniak, M.S.6
Ogretmen, B.7
Dash, R.8
Sarkar, D.9
Broaddus, W.C.10
Grant, S.11
Curiel, D.T.12
Fisher, P.B.13
Dent, P.14
-
201
-
-
34249883587
-
Induction and selective accumulation of mutant ubiquitin in CA1 pyramidal neurons after transient global ischemia
-
Yamashiro, K., Liu, R., Maeda, M., Hattori, N., Urabe, T., Induction and selective accumulation of mutant ubiquitin in CA1 pyramidal neurons after transient global ischemia. Neuroscience 147 (2007), 71–79.
-
(2007)
Neuroscience
, vol.147
, pp. 71-79
-
-
Yamashiro, K.1
Liu, R.2
Maeda, M.3
Hattori, N.4
Urabe, T.5
-
202
-
-
79961078072
-
Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegans
-
Yuan, Y., Cao, P., Smith, M.A., Kramp, K., Huang, Y., Hisamoto, N., Matsumoto, K., Hatzoglou, M., Jin, H., Feng, Z., Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegans. Plos One, 6, 2011, e22354.
-
(2011)
Plos One
, vol.6
, pp. e22354
-
-
Yuan, Y.1
Cao, P.2
Smith, M.A.3
Kramp, K.4
Huang, Y.5
Hisamoto, N.6
Matsumoto, K.7
Hatzoglou, M.8
Jin, H.9
Feng, Z.10
-
203
-
-
0035215010
-
Postischemic (6-Hour) treatment with recombinant human tissue plasminogen activator and proteasome inhibitor PS-519 reduces infarction in a rat model of embolic focal cerebral ischemia
-
Zhang, L., Zhang, Z.G., Zhang, R.L., Lu, M., Adams, J., Elliott, P.J., Chopp, M., Postischemic (6-Hour) treatment with recombinant human tissue plasminogen activator and proteasome inhibitor PS-519 reduces infarction in a rat model of embolic focal cerebral ischemia. Stroke. 32 (2001), 2926–2931.
-
(2001)
Stroke.
, vol.32
, pp. 2926-2931
-
-
Zhang, L.1
Zhang, Z.G.2
Zhang, R.L.3
Lu, M.4
Adams, J.5
Elliott, P.J.6
Chopp, M.7
-
204
-
-
84907892583
-
Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: involvement of PARK2-dependent mitophagy
-
Zhang, X., Yuan, Y., Jiang, L., Zhang, J., Gao, J., Shen, Z., Zheng, Y., Deng, T., Yan, H., Li, W., Hou, W.W., Lu, J., Shen, Y., Dai, H., Hu, W.W., Zhang, Z., Chen, Z., Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: involvement of PARK2-dependent mitophagy. Autophagy 10 (2014), 1801–1813.
-
(2014)
Autophagy
, vol.10
, pp. 1801-1813
-
-
Zhang, X.1
Yuan, Y.2
Jiang, L.3
Zhang, J.4
Gao, J.5
Shen, Z.6
Zheng, Y.7
Deng, T.8
Yan, H.9
Li, W.10
Hou, W.W.11
Lu, J.12
Shen, Y.13
Dai, H.14
Hu, W.W.15
Zhang, Z.16
Chen, Z.17
-
205
-
-
84958818563
-
Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress
-
Zhu, X., Zelmer, A., Kapfhammer, J.P., Wellmann, S., Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress. FASEB J. 30 (2016), 624–634.
-
(2016)
FASEB J.
, vol.30
, pp. 624-634
-
-
Zhu, X.1
Zelmer, A.2
Kapfhammer, J.P.3
Wellmann, S.4
|