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Volumn 23, Issue 19, 2004, Pages 3793-3802

Tissue plasminogen activator is a potent activator of PDGF-CC

Author keywords

Activation; CUB; PDGF; Proteolysis; tPA

Indexed keywords

PLASMIN; PLASMINOGEN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR CC; PROTEINASE; SERINE PROTEINASE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

EID: 6344236867     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600397     Document Type: Article
Times cited : (159)

References (42)
  • 1
    • 0035663713 scopus 로고    scopus 로고
    • Expression analysis of PDGF-C in adult and developing mouse tissues
    • Aase K, Abramsson A, Karlsson L, Betsholtz C, Eriksson U (2002) Expression analysis of PDGF-C in adult and developing mouse tissues. Mech Dev 110: 187-191
    • (2002) Mech Dev , vol.110 , pp. 187-191
    • Aase, K.1    Abramsson, A.2    Karlsson, L.3    Betsholtz, C.4    Eriksson, U.5
  • 2
    • 0036385854 scopus 로고    scopus 로고
    • Platelet-derived growth factor-B and -C and active α-receptors in medulloblastoma cells
    • Andrae J, Molander C, Smits A, Funa K, Nister M (2002) Platelet-derived growth factor-B and -C and active α-receptors in medulloblastoma cells. Biochem Biophys Res Commun 296: 604-611
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 604-611
    • Andrae, J.1    Molander, C.2    Smits, A.3    Funa, K.4    Nister, M.5
  • 4
    • 0037432766 scopus 로고    scopus 로고
    • LRP: Role in vascular wall integrity and protection from atherosclerosis
    • Boucher P, Gotthardt M, Li WP, Anderson RG, Herz J (2003) LRP: role in vascular wall integrity and protection from atherosclerosis. Science 300: 329-332
    • (2003) Science , vol.300 , pp. 329-332
    • Boucher, P.1    Gotthardt, M.2    Li, W.P.3    Anderson, R.G.4    Herz, J.5
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 6
    • 0036793520 scopus 로고    scopus 로고
    • Angiogenesis stimulated by PDGF-CC, a novel member in the PDGF family, involves activation of PDGFR-αα and -αβ receptors
    • Cao R, Bråkenhielm E, Li X, Pietras K, Widenfalk J, Östman A, Eriksson U, Cao Y (2002) Angiogenesis stimulated by PDGF-CC, a novel member in the PDGF family, involves activation of PDGFR-αα and -αβ receptors. FASEB J 16: 1575-1583
    • (2002) FASEB J , vol.16 , pp. 1575-1583
    • Cao, R.1    Bråkenhielm, E.2    Li, X.3    Pietras, K.4    Widenfalk, J.5    Östman, A.6    Eriksson, U.7    Cao, Y.8
  • 8
    • 0028043836 scopus 로고
    • The mouse tissue plasminogen activator gene 5′ flanking region directs appropriate expression in development and a seizure-enhanced response in the CNS
    • Carroll PM, Tsirka SE, Richards WG, Frohman MA, Strickland S (1994) The mouse tissue plasminogen activator gene 5′ flanking region directs appropriate expression in development and a seizure-enhanced response in the CNS. Development 120: 3173-3183
    • (1994) Development , vol.120 , pp. 3173-3183
    • Carroll, P.M.1    Tsirka, S.E.2    Richards, W.G.3    Frohman, M.A.4    Strickland, S.5
  • 9
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 10
    • 0035225553 scopus 로고    scopus 로고
    • Ham-Wasserman lecture: Role of the plasminogen system in fibrin-homeostasis and tissue remodeling
    • Collen D (2001) Ham-Wasserman lecture: role of the plasminogen system in fibrin-homeostasis and tissue remodeling. Hematology (Am Soc Hematol Educ Program) 1-9
    • (2001) Hematology (Am Soc Hematol Educ Program) , pp. 1-9
    • Collen, D.1
  • 11
    • 0014932863 scopus 로고
    • Plasminogen: Purification from human plasma by affinity chromatography
    • Deutsch DG, Mertz ET (1970) Plasminogen: purification from human plasma by affinity chromatography. Science 170: 1095-1096
    • (1970) Science , vol.170 , pp. 1095-1096
    • Deutsch, D.G.1    Mertz, E.T.2
  • 13
    • 0034706020 scopus 로고    scopus 로고
    • The mouse Pdgfc gene: Dynamic expression in embryonic tissues during organogenesis
    • Ding H, Wu X, Kim I, Tam PP, Koh GY, Nagy A (2000) The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesis. Mech Dev 96: 209-213
    • (2000) Mech Dev , vol.96 , pp. 209-213
    • Ding, H.1    Wu, X.2    Kim, I.3    Tam, P.P.4    Koh, G.Y.5    Nagy, A.6
  • 14
    • 0025978985 scopus 로고
    • Cardiac fibroblasts are predisposed to convert into myocyte phenotype: Specific effect of transforming growth factor beta
    • Eghbali M, Tomek R, Woods C, Bhambi B (1991) Cardiac fibroblasts are predisposed to convert into myocyte phenotype: specific effect of transforming growth factor beta. Proc Natl Acad Sci USA 88: 795-799
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 795-799
    • Eghbali, M.1    Tomek, R.2    Woods, C.3    Bhambi, B.4
  • 15
    • 0026583942 scopus 로고
    • PDGF α- and β-receptors activate unique and common signal transduction pathways
    • Eriksson A, Siegbahn A, Westermark B, Heldin C-H, Claesson-Welsh L (1992) PDGF α- and β-receptors activate unique and common signal transduction pathways. EMBO J 11: 543-550
    • (1992) EMBO J , vol.11 , pp. 543-550
    • Eriksson, A.1    Siegbahn, A.2    Westermark, B.3    Heldin, C.-H.4    Claesson-Welsh, L.5
  • 17
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin C-H, Westermark B (1999) Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79: 1283-1316
    • (1999) Physiol Rev , vol.79 , pp. 1283-1316
    • Heldin, C.-H.1    Westermark, B.2
  • 18
    • 0020472522 scopus 로고
    • Kinetics of the activation of plasminogen by human tissue plasminogen activator-role of fibrin
    • Hoylaerts M, Rijken DC, Lijnen HR, Collen D (1982) Kinetics of the activation of plasminogen by human tissue plasminogen activator-role of fibrin. J Biol Chem 257: 2912-2919
    • (1982) J Biol Chem , vol.257 , pp. 2912-2919
    • Hoylaerts, M.1    Rijken, D.C.2    Lijnen, H.R.3    Collen, D.4
  • 19
    • 0026462546 scopus 로고
    • The plasminogen-plasmin system in malignancy
    • Kwaan HC (1992) The plasminogen-plasmin system in malignancy. Cancer Metast Rev 11: 291-311
    • (1992) Cancer Metast Rev , vol.11 , pp. 291-311
    • Kwaan, H.C.1
  • 21
    • 0037434985 scopus 로고    scopus 로고
    • PDGF-D is a potent transforming and angiogenic growth factor
    • Li H, Fredriksson L, Li X, Eriksson U (2003) PDGF-D is a potent transforming and angiogenic growth factor. Oncogene 22: 1501-1510
    • (2003) Oncogene , vol.22 , pp. 1501-1510
    • Li, H.1    Fredriksson, L.2    Li, X.3    Eriksson, U.4
  • 22
    • 0037380709 scopus 로고    scopus 로고
    • Novel PDGF family members: PDGF-C and PDGF-D
    • Li X, Eriksson U (2003) Novel PDGF family members: PDGF-C and PDGF-D. Cytokine Growth Factor Rev 14: 91-98
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 91-98
    • Li, X.1    Eriksson, U.2
  • 24
    • 0036645057 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: Evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors
    • Lokker NA, Sullivan CM, Hollenbach SJ, Israel MA, Giese NA (2002) Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors. Cancer Res 62: 3729-3735
    • (2002) Cancer Res , vol.62 , pp. 3729-3735
    • Lokker, N.A.1    Sullivan, C.M.2    Hollenbach, S.J.3    Israel, M.A.4    Giese, N.A.5
  • 25
    • 0036937798 scopus 로고    scopus 로고
    • Structural and functional relation of neuropilins
    • Nakamura F, Goshima Y (2002) Structural and functional relation of neuropilins. Adv Exp Med Biol 515: 55-69
    • (2002) Adv Exp Med Biol , vol.515 , pp. 55-69
    • Nakamura, F.1    Goshima, Y.2
  • 27
    • 0026685187 scopus 로고
    • PDGF-AA and PDGF-BB biosynthesis: Proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly
    • Östman A, Thyberg J, Westermark B, Heldin C-H (1992) PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly. J Cell Biol 118: 509-519
    • (1992) J Cell Biol , vol.118 , pp. 509-519
    • Östman, A.1    Thyberg, J.2    Westermark, B.3    Heldin, C.-H.4
  • 28
    • 0019987224 scopus 로고
    • Studies on the kinetics of plasminogen activation by tissue plasminogen activator
    • Ranby M (1982) Studies on the kinetics of plasminogen activation by tissue plasminogen activator. Biochim Biophys Acta 704: 461-469
    • (1982) Biochim Biophys Acta , vol.704 , pp. 461-469
    • Ranby, M.1
  • 29
    • 0023866970 scopus 로고
    • Tissue plasminogen activator mRNA in murine tissues
    • Rickles RJ, Strickland S (1988) Tissue plasminogen activator mRNA in murine tissues. FEBS Lett 229: 100-106
    • (1988) FEBS Lett , vol.229 , pp. 100-106
    • Rickles, R.J.1    Strickland, S.2
  • 30
    • 0037379743 scopus 로고    scopus 로고
    • The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity
    • Siegfried G, Khatib AM, Benjannet S, Chretien M, Seidah NG (2003) The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity. Cancer Res 63: 1458-1463
    • (2003) Cancer Res , vol.63 , pp. 1458-1463
    • Siegfried, G.1    Khatib, A.M.2    Benjannet, S.3    Chretien, M.4    Seidah, N.G.5
  • 31
    • 0034912401 scopus 로고    scopus 로고
    • Tissue plasminogen activator in nervous system function and dysfunction
    • Strickland S (2001) Tissue plasminogen activator in nervous system function and dysfunction. Thromb Haemost 86: 138-143
    • (2001) Thromb Haemost , vol.86 , pp. 138-143
    • Strickland, S.1
  • 32
    • 0030768740 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of potent thrombin inhibitors: Piperazides of 3-amidinophenylalanine
    • Sturzebecher J, Prasa D, Hauptmann J, Vieweg H, Wikstrom P (1997) Synthesis and structure-activity relationships of potent thrombin inhibitors: piperazides of 3-amidinophenylalanine. J Med Chem 40: 3091-3099
    • (1997) J Med Chem , vol.40 , pp. 3091-3099
    • Sturzebecher, J.1    Prasa, D.2    Hauptmann, J.3    Vieweg, H.4    Wikstrom, P.5
  • 33
    • 0033613123 scopus 로고    scopus 로고
    • Reverse biochemistry: Use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue
    • Takeuchi T, Shuman MA, Craik CS (1999) Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue. Proc Natl Acad Sci USA 96: 11054-11061
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11054-11061
    • Takeuchi, T.1    Shuman, M.A.2    Craik, C.S.3
  • 34
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • The National Institute of Neurological Disorders and Stroke rtPA Stroke Study Group (1995) Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 333: 1581-1587
    • (1995) N Engl J Med , vol.333 , pp. 1581-1587
  • 35
    • 0033066410 scopus 로고    scopus 로고
    • Structure and functions of the interaction domains of C1r and C1s: Keystones of the architecture of the C1 complex
    • Thielens NM, Bersch B, Hernandez JF, Arlaud GJ (1999) Structure and functions of the interaction domains of C1r and C1s: keystones of the architecture of the C1 complex. Immunopharmacology 42: 3-13
    • (1999) Immunopharmacology , vol.42 , pp. 3-13
    • Thielens, N.M.1    Bersch, B.2    Hernandez, J.F.3    Arlaud, G.J.4
  • 36
    • 0036549939 scopus 로고    scopus 로고
    • Tissue plasminogen activator as a modulator of neuronal survival and function
    • Tsirka SE (2002) Tissue plasminogen activator as a modulator of neuronal survival and function. Biochem Soc Trans 30: 222-225
    • (2002) Biochem Soc Trans , vol.30 , pp. 222-225
    • Tsirka, S.E.1
  • 37
    • 0035826891 scopus 로고    scopus 로고
    • Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFD genes
    • Uutela M, Lauren J, Bergsten E, Li X, Horelli-Kuitunen N, Eriksson U, Alitalo K (2001) Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFD genes. Circulation 103: 2242-2247
    • (2001) Circulation , vol.103 , pp. 2242-2247
    • Uutela, M.1    Lauren, J.2    Bergsten, E.3    Li, X.4    Horelli-Kuitunen, N.5    Eriksson, U.6    Alitalo, K.7
  • 38
  • 39
    • 0034689030 scopus 로고    scopus 로고
    • The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber out-growth through a proteoglycan substrate
    • Wu YP, Siao CJ, Lu W, Sung TC, Frohman MA, Milev P, Bugge TH, Degen JL, Levine JM, Margolis RU, Tsirka SE (2000) The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber out-growth through a proteoglycan substrate. J Cell Biol 148:1295-1304
    • (2000) J Cell Biol , vol.148 , pp. 1295-1304
    • Wu, Y.P.1    Siao, C.J.2    Lu, W.3    Sung, T.C.4    Frohman, M.A.5    Milev, P.6    Bugge, T.H.7    Degen, J.L.8    Levine, J.M.9    Margolis, R.U.10    Tsirka, S.E.11
  • 41
    • 0345824713 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein
    • Yepes M, Sandkvist M, Moore EG, Bugge TH, Strickland DK, Lawrence DA (2003) Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. J Clin Invest 112: 1533-1540
    • (2003) J Clin Invest , vol.112 , pp. 1533-1540
    • Yepes, M.1    Sandkvist, M.2    Moore, E.G.3    Bugge, T.H.4    Strickland, D.K.5    Lawrence, D.A.6
  • 42
    • 0035242001 scopus 로고    scopus 로고
    • PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors
    • Zwerner JP, May WA (2001) PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors. Oncogene 20: 626-633
    • (2001) Oncogene , vol.20 , pp. 626-633
    • Zwerner, J.P.1    May, W.A.2


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