Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic Priming

EBioMedicine

Volumn 2, Issue 6, 2015, Pages 528-535

  Rzechorzek, Nina Marie ^a,b   Connick, Peter ^a,c   Patani, Rickie ^c,d   Selvaraj, Bhuvaneish Thangaraj ^a,b   Chandran, Siddharthan ^a,b,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Endoplasmic reticulum stress; Hypothermia; Neuroprotection; Preconditioning; Proteostasis; Unfolded protein response

Indexed keywords

COLD SHOCK PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROTEIN IRE1; PROTEIN KINASE R; TUNICAMYCIN; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; REGULATORY FACTOR X TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ARTICLE; BRAIN CELL; BRAIN TISSUE; COLD STRESS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHERMIA; IMMUNOCYTOCHEMISTRY; OXIDATIVE STRESS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WESTERN BLOTTING; BRAIN CORTEX; CELL CULTURE; COLD SHOCK RESPONSE; CYTOLOGY; ENDOPLASMIC RETICULUM; GENETICS; INDUCED HYPOTHERMIA; METABOLISM; NERVE CELL; NEUROPROTECTION; PATHOLOGY; PHYSIOLOGY; PROCEDURES;

CELLS, CULTURED; CEREBRAL CORTEX; COLD-SHOCK RESPONSE; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HUMANS; HYPOTHERMIA, INDUCED; NEURONS; NEUROPROTECTION; OXIDATIVE STRESS; PLURIPOTENT STEM CELLS; TRANSCRIPTION FACTORS; TUNICAMYCIN; UNFOLDED PROTEIN RESPONSE;

EID: 84949548693     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.04.004     Document Type: Article

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