Prolonged bihemispheric alterations in unfolded protein response related gene expression after experimental stroke

Brain Research

Volumn 1087, Issue 1, 2006, Pages 60-66

  Rissanen, Anna ^a   Sivenius, Juhani ^b   Jolkkonen, Jukka ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Endoplasmic reticulum; Gene expression; Middle cerebral artery occlusion (MCAO); Spontaneous functional recovery; Striatum; Unfolded protein response

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; GENE PRODUCT; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; PKR LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN IRE1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN REGION; CELL FUNCTION; CHRONOLOGY; CONTROLLED STUDY; CONVALESCENCE; CORPUS STRIATUM; ENDOPLASMIC RETICULUM; EXPERIMENTATION; GENE EXPRESSION; GENE IDENTIFICATION; HEMISPHERE; IN SITU HYBRIDIZATION; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN FOLDING; RAT; SENSORIMOTOR CORTEX; SIGNAL TRANSDUCTION; STRESS; STROKE; TASK PERFORMANCE;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; FUNCTIONAL LATERALITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 33646860572     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.02.095     Document Type: Article

References (25)

1. Biernaskie J., and Corbett D. Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury. J. Neurosci. 21 (2001) 5272-5280
2. Biernaskie J., Chernenko G., and Corbett D. Efficacy of rehabilitative experience declines with time after focal ischemic brain injury. J. Neurosci. 24 (2004) 1245-1254
3. Biernaskie J., Szymanska A., Windle V., and Corbett D. Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats. Eur. J. Neurosci. 21 (2005) 989-999
4. DeGracia D.J., Kumar R., Owen C.R., Krause G.S., and White B.C. Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death. J. Cereb. Blood Flow Metab. 22 (2002) 127-141
5. Deryck M., Van Reempts J., Borgers M., Wauquier A., and Janssen P.A. Photochemical stroke model: flunarizine prevents sensorimotor deficits after neocortical infarcts in rats. Stroke 20 (1989) 1383-1390
6. Hayashi T., Saito A., Okuno S., Ferrand-Drake M., Dodd R.L., Nishi T., Maier C.M., Kinouchi H., and Chan P.H. Oxidative damage to the endoplasmic reticulum is implicated in ischemic neuronal cell death. J. Cereb. Blood Flow Metab. 23 (2003) 1117-1128
7. Jolkkonen J., Palamero Gallagherb N., Zillesband K., and Sivenius J. Behavioral deficits and recovery following transient focal cerebral ischemia in rats: glutamatergic and GABAergic receptor densities. Behav. Brain Res. 138 (2003) 187-200
8. Kolb B., Brown R., Witt-Lajeunesse A., and Gibb R. Neural compensations after lesion of the cerebral cortex. Neural Plast. 8 (2001) 1-16
9. 2+ increases and cell death. J. Biol. Chem. 273 (1998) 12858-12862
10. Longa E., Weinstein P.R., Carlson S., and Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20 (1989) 84-91
11. Loring J.F., Porter J.G., Seilhamer J., Kaser M.R., and Wesselschmidt R. A gene expression profile of embryonic stem cells and embryonic stem cell-derived neurons. Restor. Neurol. Neurosci. 18 (2001) 81-88
12. Martin de la Vega C., Burda J., Nemethova M., Quevedo C., Alcazar A., Martin M.E., Danielisova V., Fando J.L., and Salinas M. Possible mechanisms involved in the down-regulation of translation during transient global ischaemia in the rat brain. Biochem. J. 357 (2001) 819-826
13. Nudo R.J., Plautz E.J., and Frost S.B. Role of adaptive plasticity in recovery of function after damage to motor cortex. Muscle Nerve 24 (2001) 1000-1019 (Plasticity in motor cortex)
14. Özcan U., Qiong C., Yilmaz E., Lee A.H., Iwakoshi N.N., Özdelen E., Tuncman G., Görguen C., Glimcher L.H., and Hotamisligil G.S. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306 (2004) 457-461
15. Paschen W. Endoplasmic reticulum: a primary target in various acute disorders and degenerative diseases of the brain. Cell Calcium 34 (2003) 365-383
16. Paschen W. Shutdown of translation: lethal or protective? Unfolded protein response versus apoptosis. J. Cereb. Blood Flow Metab. 23 (2003) 773-779
17. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1997), Academic Press, Sydney
18. Puurunen K., Jolkkonen J., Sirviö J., and Haapalinna A. An α-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats. Neuropharmacology 40 (2001) 597-606
19. Qi X., Okuma Y., Hosoi T., and Nomura Y. Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction. J. Pharmacol. Exp. Ther. 311 (2004) 388-393
20. Rao R.V., Peel A., Logvinova A., del Rio G., Hermel E., Yokota T., Goldsmith P.C., Ellerby L.M., Ellerby H.M., and Bredesen D.E. Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78. FEBS Lett. 514 (2002) 122-128
21. Schröder M., and Kaufman R.J. The mammalian unfolded protein response. Annu. Rev. Biochem. 74 (2005) 739-789
22. Toyoda K., Fujii K., Kamouchi M., Nakane H., Arihiro S., Okada Y., Ibayashi S., and Iida M. Free radical scavenger, edaravone, in stroke with internal carotid artery occlusion. J. Neurol. Sci. 221 (2004) 11-17
23. Urano F., Bertolotti A., and Ron D. IRE1 and efferent signaling from the endoplasmic reticulum. J. Cell Sci. 113 (2000) 3697-3702
24. Wang Y., Shen J., Arenzana N., Tirasophon W., Kaufman R.J., and Prywes R. Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response. J. Biol. Chem. 275 (2000) 27013-27020
25. Wisden W., and Morris B.J. In situ hybridization with synthetic oligonucleotide probes. In: Wisden W., and Morris B.J. (Eds). In Situ Hybridization Protocols for Neurobiology (1994), Academic Press, London 1-34