The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria

Autophagy

Volumn 9, Issue 11, 2013, Pages 1750-1757

  Jin, Seok Min ^a   Youle, Richard J ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

LONP; Mitochondria; Mitophagy; PARK2 Parkin; PINK1; Unfolded protein response

Indexed keywords

CHAPERONE; PROTEINASE; UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; GENE INTERACTION; HUMAN; HUMAN CELL; MITOCHONDRION; MITOPHAGY; MUTATION; PARKINSON DISEASE; PROTEIN FOLDING; QUALITY CONTROL; UNFOLDED PROTEIN RESPONSE;

LONP; MITOCHONDRIA; MITOPHAGY; PARK2/PARKIN; PINK1; UNFOLDED PROTEIN RESPONSE;

GENE DELETION; HELA CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; ORNITHINE CARBAMOYLTRANSFERASE; PROTEIN FOLDING; PROTEIN KINASES; PROTEIN UNFOLDING; UBIQUITIN-PROTEIN LIGASES; UNFOLDED PROTEIN RESPONSE;

EID: 84887486172     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.26122     Document Type: Article

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