Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons

Journal of Biological Chemistry

Volumn 288, Issue 17, 2013, Pages 12161-12174

  Huang, Qian ^a   Wang, Hu ^a   Perry, Seth W ^b   Figueiredo Pereira, Maria E ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b University of Rochester   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN ACTIVATION; CELL-DEATH PATHWAYS; ELECTRON TRANSPORT CHAIN; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL DYSFUNCTION; NEUROFIBRILLARY TANGLES; PROTEIN DEGRADATION; PROTEIN TURNOVERS;

CELL DEATH; NEURODEGENERATIVE DISEASES; PROTEINS;

NEURONS;

20S PROTEASOME; 26S PROTEASOME; ADENOSINE TRIPHOSPHATE; CALPAIN; CASPASE 3; CITRININ; OLIGOMYCIN; PROTEASOME; REGULATORY PARTICLE NON ADENOSINE TRIPHOSPHATASE 10; ROTENONE; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DOWN REGULATION; ELECTRON TRANSPORT; EMBRYO; FEMALE; LYSOSOME; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; RAT; UBIQUITINATION;

ANIMALS; CALPAIN; CASPASE 3; ENZYME STABILITY; MITOCHONDRIA; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; TAU PROTEINS; UBIQUITINATED PROTEINS;

RATTUS;

EID: 84876903554     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.464552     Document Type: Article

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