Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity

Oncotarget

Volumn 6, Issue 28, 2015, Pages 24922-24934

  Jabouille, Arnaud ^a,b   Delugin, Maylis ^a,b   Pineau, Raphaël ^b   Dubrac, Alexandre ^c   Soulet, Fabienne ^a,b   Lhomond, Stéphanie ^a,b   Pallares Lupon, Nestor ^a,b   Prats, Hervé ^c   Bikfalvi, Andreas ^a,b   Chevet, Eric ^a,b,d,e   Touriol, Christian ^c   Moenner, Michel ^a,b,f  

^a INSERM   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c CHU RANGUEIL   (France)

^d CENTRE EUGÈNE MARQUIS   (France)

^e UNIVERSITÉ DE RENNES 1   (France)

^f Institut de Biochimie et Genetique Cellulaires   (France)

Author keywords

Angiogenesis; Glioblastoma; Invasion; Mesenchymal differentiation; Pathology Section; Perivascular growth

Indexed keywords

MEMBRANE PROTEIN; PROTEIN IRE1 ALPHA; RIBONUCLEASE; UNCLASSIFIED DRUG; DOXYCYCLINE; ERN1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; IN VITRO STUDY; MESENCHYME CELL; MOUSE; NONHUMAN; PHENOTYPE; TUMOR GROWTH; TUMOR INVASION; TUMOR VASCULARIZATION; TUMOR XENOGRAFT; ANIMAL; BRAIN NEOPLASMS; CELL MOTION; CELL PROLIFERATION; CONFOCAL MICROSCOPY; DRUG EFFECTS; DRUG SCREENING; ENZYMOLOGY; GENETICS; HUMAN; IMMUNOBLOTTING; KAPLAN MEIER METHOD; METABOLISM; MUTATION; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME; VASCULARIZATION;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOXYCYCLINE; ENDORIBONUCLEASES; GLIOBLASTOMA; HUMANS; IMMUNOBLOTTING; KAPLAN-MEIER ESTIMATE; MICE; MICROSCOPY, CONFOCAL; MUTATION; NEOPLASM INVASIVENESS; NEOVASCULARIZATION, PATHOLOGIC; PROTEIN-SERINE-THREONINE KINASES; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84944474756     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4679     Document Type: Article

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