Targeting cancer by binding iron: Dissecting cellular signaling pathways

Oncotarget

Volumn 6, Issue 22, 2015, Pages 18748-18779

  Lui, Goldie Y L ^a   Kovacevic, Zaklina ^a   Richardson, Vera ^a   Merlot, Angelica M ^a   Kalinowski, Danuta S ^a   Richardson, Des R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Cancer; Chelators; Iron; Signaling; Thiosemicarbazones

Indexed keywords

3 AMINOPICOLINALDEHYDE THIOSEMICARBAZONE; CARBOPLATIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; CYCLOPHOSPHAMIDE; DEFERASIROX; DEFEROXAMINE MESYLATE; DI 2 PYRIDYLKETONE 2 METHYL 3 THIOSEMICARBAZONE; DI 2 PYRIDYLKETONE 4,4 DIMETHYL 3 THIOSEMICARBAZONE; DI 2 PYRIDYLKETONE THIOSEMICARBAZONE; ETOPOSIDE; GELATINASE B; HYDRAZONE DERIVATIVE; IRON CHELATING AGENT; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; NERVE CELL ADHESION MOLECULE; OCCLUDIN; PROTEIN KINASE B; RAF PROTEIN; RAS PROTEIN; RIBONUCLEOTIDE REDUCTASE; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN; ANTINEOPLASTIC AGENT; IRON; THIOSEMICARBAZONE DERIVATIVE;

ANEMIA; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER GROWTH; CELL CYCLE PROGRESSION; CELL PROLIFERATION; DNA DAMAGE; DNA SYNTHESIS; DRUG HALF LIFE; DRUG POTENCY; DRUG TARGETING; DRUG TOLERABILITY; ENDOPLASMIC RETICULUM STRESS; EPITHELIAL MESENCHYMAL TRANSITION; ERYTHROID CELL; FATIGUE; HUMAN; HYDROPHILICITY; HYPOTENSION; HYPOXIA; INJECTION SITE PAIN; INJECTION SITE SWELLING; INTRACELLULAR SIGNALING; IRON BINDING CAPACITY; IRON METABOLISM; IRON OVERLOAD; IRON STORAGE; IRON TRANSPORT; LEUKEMIA; LEUKOPENIA; LIPID PEROXIDATION; LIVER CELL CARCINOMA; LUNG CARCINOMA; MANTLE CELL LYMPHOMA; METASTASIS; METHEMOGLOBINEMIA; MOLECULAR DYNAMICS; MYELOID LEUKEMIA; NAUSEA; NEUROBLASTOMA; NEUTROPENIA; NONHUMAN; OVERALL SURVIVAL; OXIDATION; PATIENT COMPLIANCE; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SURVIVAL RATE; THROMBOCYTOPENIA; UPREGULATION; VOMITING; ANIMAL; DRUG EFFECTS; METABOLISM; MOLECULAR MODEL; MOLECULARLY TARGETED THERAPY; NEOPLASMS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; IRON; IRON CHELATING AGENTS; MODELS, MOLECULAR; MOLECULAR TARGETED THERAPY; NEOPLASMS; SIGNAL TRANSDUCTION; THIOSEMICARBAZONES;

EID: 84938833826     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4349     Document Type: Article

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