Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

EMBO Journal

Volumn 17, Issue 9, 1998, Pages 2596-2606

  Saitoh, Masao ^a   Nishitoh, Hideki ^a   Fujii, Makiko ^a   Takeda, Kohsuke ^a   Tobiume, Kei ^a   Sawada, Yasuhiro ^a   Kawabata, Masahiro ^a   Miyazono, Kohei ^a   Ichijo, Hidenori ^b  

^a CANCER INSTITUTE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; ASK1; MAP kinase; Redox; Thioredoxin

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; APOPTOSIS SIGNAL REGULATING KINASE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; THIOREDOXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME REGULATION; GENETIC SCREENING; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BRAIN; CELL LINE; CHLORIDES; CULTURE MEDIA, SERUM-FREE; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; HYDROGEN PEROXIDE; L CELLS (CELL LINE); MAMMALS; MAP KINASE KINASE KINASES; MICE; OXIDATION-REDUCTION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; THIOREDOXIN; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; ZINC COMPOUNDS;

ANIMALIA; MAMMALIA;

EID: 0032080283     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.9.2596     Document Type: Article

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