Human STEAP3 maintains tumor growth under hypoferric condition

Experimental Cell Research

Volumn 317, Issue 18, 2011, Pages 2582-2591

  Isobe, Taichi ^a   Baba, Eishi ^a   Arita, Shuji ^a   Komoda, Masato ^a   Tamura, Shingo ^a   Shirakawa, Tsuyoshi ^a   Ariyama, Hiroshi ^a   Takaishi, Shigeo ^a   Kusaba, Hitoshi ^a   Ueki, Takashi ^a   Akashi, Koichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Ferritins; Iron; Neoplasms; Transferrin; TSAP6

Indexed keywords

FERRITIN; IRON; MEMBRANE PROTEIN; MESSENGER RNA; SIX TRANSMEMBRANE EPITHELIAL ANTIGEN OF THE PROSTATE FAMILY MEMBER 3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IRON DEFICIENCY; IRON STORAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAJI CELL; TUMOR GROWTH;

MUS;

EID: 80053560563     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2011.07.022     Document Type: Article

References (35)

1. Letendre E.D. Iron metabolism during infection and neoplasia. Cancer Metastasis Rev. 1987, 6:41-53.
2. Lill R., Diekert K., Kaut A., Lange H., Pelzer W., Prohl C., Kispal G. The essential role of mitochondria in the biogenesis of cellular iron-sulfur proteins. Biol. Chem. 1999, 380:1157-1166.
3. Thelander L., Graslund A., Thelander M. Continual presence of oxygen and iron required for mammalian ribonucleotide reduction: possible regulation mechanism. Biochem. Biophys. Res. Commun. 1983, 110:859-865.
4. Ohgami R.S., Campagna D.R., Greer E.L., Antiochos B., McDonald A., Chen J., Sharp J.J., Fujiwara Y., Barker J.E., Fleming M.D. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat. Genet. 2005, 37:1264-1269.
5. Fleming M.D., Romano M.A., Su M.A., Garrick L.M., Garrick M.D., Andrews N.C. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc. Natl. Acad. Sci. USA 1998, 95:1148-1153.
6. Sanchez-Pulido L., Rojas A.M., Valencia A., Martinez A.C., Andrade M.A. ACRATA: a novel electron transfer domain associated to apoptosis and cancer. BMC Cancer 2004, 4:98.
7. Passer B.J., Nancy-Portebois V., Amzallag N., Prieur S., Cans C., Roborel de Climens A., Fiucci G., Bouvard V., Tuynder M., Susini L., Morchoisne S., Crible V., Lespagnol A., Dausset J., Oren M., Amson R., Telerman A. The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase. Proc. Natl. Acad. Sci. USA 2003, 100:2284-2289.
8. Ohgami R.S., Campagna D.R., McDonald A., Fleming M.D. The Steap proteins are metalloreductases. Blood 2006, 108:1388-1394.
9. Amson R.B., Nemani M., Roperch J.P., Israeli D., Bougueleret L., Le Gall I., Medhioub M., Linares-Cruz G., Lethrosne F., Pasturaud P., Piouffre L., Prieur S., Susini L., Alvaro V., Millasseau P., Guidicelli C., Bui H., Massart C., Cazes L., Dufour F., Bruzzoni-Giovanelli H., Owadi H., Hennion C., Charpak G., Telerman A., et al. Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene. Proc. Natl. Acad. Sci. USA 1996, 93:3953-3957.
10. Zhang X., Steiner M.S., Rinaldy A., Lu Y. Apoptosis induction in prostate cancer cells by a novel gene product, pHyde, involves caspase-3. Oncogene 2001, 20:5982-5990.
11. Coulouarn C., Derambure C., Lefebvre G., Daveau R., Hiron M., Scotte M., Francois A., Daveau M., Salier J.P. Global gene repression in hepatocellular carcinoma and fetal liver, and suppression of dudulin-2 mRNA as a possible marker for the cirrhosis-to-tumor transition. J. Hepatol. 2005, 42:860-869.
12. Porkka K.P., Nupponen N.N., Tammela T.L., Vessella R.L., Visakorpi T. Human pHyde is not a classical tumor suppressor gene in prostate cancer. Int. J. Cancer 2003, 106:729-735.
13. Yu X., Harris S.L., Levine A.J. The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res. 2006, 66:4795-4801.
14. Lespagnol A., Duflaut D., Beekman C., Blanc L., Fiucci G., Marine J.C., Vidal M., Amson R., Telerman A. Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice. Cell Death Differ. 2008, 15:1723-1733.
15. Denzer K., Kleijmeer M.J., Heijnen H.F., Stoorvogel W., Geuze H.J. Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J. Cell Sci. 2000, 113(Pt 19):3365-3374.
16. Thery C., Zitvogel L., Amigorena S. Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2002, 2:569-579.
17. Fevrier B., Raposo G. Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr. Opin. Cell Biol. 2004, 16:415-421.
18. van Niel G., Porto-Carreiro I., Simoes S., Raposo G. Exosomes: a common pathway for a specialized function. J. Biochem. 2006, 140:13-21.
19. Andreola G., Rivoltini L., Castelli C., Huber V., Perego P., Deho P., Squarcina P., Accornero P., Lozupone F., Lugini L., Stringaro A., Molinari A., Arancia G., Gentile M., Parmiani G., Fais S. Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J. Exp. Med. 2002, 195:1303-1316.
20. Skog J., Wurdinger T., van Rijn S., Meijer D.H., Gainche L., Sena-Esteves M., Curry W.T., Carter B.S., Krichevsky A.M., Breakefield X.O. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol. 2008, 10:1470-1476.
21. Arita S., Baba E., Shibata Y., Niiro H., Shimoda S., Isobe T., Kusaba H., Nakano S., Harada M. B cell activation regulates exosomal HLA production. Eur. J. Immunol. 2008, 38:1423-1434.
22. Klausner R.D., Rouault T.A., Harford J.B. Regulating the fate of mRNA: the control of cellular iron metabolism. Cell 1993, 72:19-28.
23. Kovar J., Valenta T., Stybrova H. Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro. In Vitro Cell. Dev. Biol. Anim. 2001, 37:450-458.
24. Morelli F., Peluso G., Petillo O., Giannattasio A., Filosa S., Motta C.M., Tammaro S., Zatterale A., Calzone R., Budillon A., Carteni M., de Maria S., Costanza M.R., Nigro A., Petrazzuolo M., Buommino E., Rizzo M., Capasso G., Baiano S., Moscatiello F., Ravagnan G., Fuggetta M.P., Tajana G., Stiuso P., Metafora B.M., Metafora V., Metafora S. The immunomodulatory protein SV-IV protects serum-deprived cells against apoptosis but not against G0/G1 arrest: possible implications for the survival of implanting embryo. J. Cell. Physiol. 2007, 212:610-625.
25. Le N.T., Richardson D.R. The role of iron in cell cycle progression and the proliferation of neoplastic cells. Biochim. Biophys. Acta 2002, 1603:31-46.
26. Weinberg E.D. The role of iron in cancer. Eur. J. Cancer Prev. 1996, 5:19-36.
27. Hann H.W., Stahlhut M.W., Menduke H. Iron enhances tumor growth. Observation on spontaneous mammary tumors in mice. Cancer 1991, 68:2407-2410.
28. Lipinski P., Drapier J.C., Oliveira L., Retmanska H., Sochanowicz B., Kruszewski M. Intracellular iron status as a hallmark of mammalian cell susceptibility to oxidative stress: a study of L5178Y mouse lymphoma cell lines differentially sensitive to H(2)O(2). Blood 2000, 95:2960-2966.
29. Nicolas G., Bennoun M., Devaux I., Beaumont C., Grandchamp B., Kahn A., Vaulont S. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc. Natl. Acad. Sci. USA 2001, 98:8780-8785.
30. Fukuchi K., Tomoyasu S., Watanabe H., Kaetsu S., Tsuruoka N., Gomi K. Iron deprivation results in an increase in p53 expression. Biol. Chem. Hoppe Seyler 1995, 376:627-630.
31. Truksa J., Kovar J., Valenta T., Ehrlichova M., Polak J., Naumann P.W. Iron deprivation induces apoptosis independently of p53 in human and murine tumour cells. Cell Prolif. 2003, 36:199-213.
32. Campillos M., Cases I., Hentze M.W., Sanchez M. SIREs: searching for iron-responsive elements. Nucleic Acids Res. 2010, 38:W360-W367. (Suppl.).
33. Abusamra A.J., Zhong Z., Zheng X., Li M., Ichim T.E., Chin J.L., Min W.P. Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis. Blood Cells Mol. Dis. 2005, 35:169-173.
34. Savina A., Furlan M., Vidal M., Colombo M.I. Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J. Biol. Chem. 2003, 278:20083-20090.
35. Savina A., Fader C.M., Damiani M.T., Colombo M.I. Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner. Traffic 2005, 6:131-143.