Targeting the metastasis suppressor, NDRG1, using novel iro chelators: Regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway

Molecular Pharmacology

Volumn 83, Issue 2, 2013, Pages 454-469

  Sun, Jing ^a   Zhang, Daohai ^b   Zheng, Ying ^a   Zhao, Qian ^a   Zheng, Minhua ^a   Kovacevic, Zaklina ^b   Richardson, Des R ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DEFEROXAMINE; IRON CHELATING AGENT; MYC PROTEIN; MYOSIN LIGHT CHAIN 2; N MYC DOWNSTREAM REGULATED GENE 1; PHOSPHORYLATED MYOSIN LIGHT CHAIN 2; RHO ASSOCIATED COILED COIL CONTAINING PROTEIN KINASE 1; RHO KINASE; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CELL STRUCTURE; COLORECTAL CANCER; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; METASTASIS; POLYMERIZATION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS FIBER; TUMOR CELL;

ACTINS; CARDIAC MYOSINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL MOVEMENT; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HT29 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IRON CHELATING AGENTS; MOLECULAR TARGETED THERAPY; MYOSIN LIGHT CHAINS; NEOPLASM METASTASIS; PHOSPHORYLATION; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; STRESS FIBERS; THIOSEMICARBAZONES;

EID: 84872735807     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.112.083097     Document Type: Article

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