Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 43, 2004, Pages 15313-15317

  Harada, Hisashi ^a,b   Quearry, Bonnie ^a   Ruiz Vela, Antonio ^b   Korsmeyer, Stanley J ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Apoptosis BCL 2 family; BH3 only; Mitogen activated protein kinase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BIM PROTEIN; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHORYLASE; PROTEIN BAX;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; ELECTROPORATION; ENZYMATIC ASSAY; ENZYME PHOSPHORYLATION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SURVIVAL RATE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CARRIER PROTEINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 7444243152     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0406837101     Document Type: Article

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