A mechanism of repression of TGFfβ/Smad signaling by oncogenic Ras

Genes and Development

Volumn 13, Issue 7, 1999, Pages 804-816

  Kretzschmar, Marcus ^a,b   Doody, Jacqueline ^a   Timokhina, Inna ^a,b   Massagué, Joan ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Growth inhibition; MAP kinase; Ras; Smad; TGF

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; DNA BINDING PROTEIN; LUCIFERASE; MAP2K1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; RAS PROTEIN; SMAD2 PROTEIN; SMAD2 PROTEIN, HUMAN; SMAD3 PROTEIN; SMAD3 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; COMPLEX FORMATION; DNA BINDING; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; GENE REPRESSION; GROWTH INHIBITION; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CELL LINE; CELL NUCLEUS; CELL STRAIN COS1; CELL TRANSFORMATION; COLON TUMOR; DOSE RESPONSE; DRUG ANTAGONISM; GENETIC TRANSFECTION; HUMAN; METABOLISM; PHOSPHORYLATION; TIME;

ANIMALIA;

ANIMALS; CELL LINE; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; COS CELLS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUCIFERASES; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, GENETIC; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RAS PROTEINS; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0033106484     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.7.804     Document Type: Article

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