The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of ß-catenin through mechanisms involving FRAT1 and PAK4

Journal of Cell Science

Volumn 127, Issue 14, 2014, Pages 3116-3130

  Jin, Runsen ^a,b   Liu, Wensheng ^a,b   Menezes, Sharleen ^b   Yue, Fei ^a   Zheng, Minhua ^a,c   Kovacevic, Zaklina ^b   Richardson, Des R ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF SYDNEY   (Australia)

^c The Central Hospital of Minhang District   (China)

Author keywords

FRAT1; Metastasis suppressor; NDRG1; PAK4; catenin

Indexed keywords

APC PROTEIN; ATAXIN 1; BETA CATENIN; BINDING PROTEIN; CREATINE KINASE; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3; P21 ACTIVATED KINASE 4; PROTEIN; PROTEIN FREQUENTLY REARRANGED IN ADVANCED T CELL LYMPHOMA 1; UNCLASSIFIED DRUG; WNT1 PROTEIN; CELL CYCLE PROTEIN; CTNNB1 PROTEIN, HUMAN; FRAT1 PROTEIN, HUMAN; N-MYC DOWNSTREAM-REGULATED GENE 1 PROTEIN; ONCOPROTEIN; P21 ACTIVATED KINASE; PAK4 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ARTICLE; CELL MEMBRANE; CELL NUCLEUS; CONTROLLED STUDY; HT 29 CELL LINE; HUMAN; HUMAN CELL; METASTASIS INHIBITION; N MYC DOWNSTREAM REGULATED GENE 1; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; SUPPRESSOR GENE; UPREGULATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; HCT116 CELL LINE; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

BETA CATENIN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; GENE SILENCING; HCT116 CELLS; HT29 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; P21-ACTIVATED KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84904350451     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.147835     Document Type: Article

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