The metastasis suppressor, N-myc Downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells

Journal of Biological Chemistry

Volumn 289, Issue 14, 2014, Pages 9692-9709

  Sahni, Sumit ^a   Bae, Dong Hun ^a   Lane, Darius J R ^a   Kovacevic, Zaklina ^a   Kalinowski, Danuta S ^a   Jansson, Patric J ^a   Richardson, Des R ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHELATION; CHEMICAL ACTIVATION; COPPER COMPOUNDS; ENZYMES; GENES; IRON COMPOUNDS; PATHOLOGY; REDOX REACTIONS;

APOPTOTIC MARKERS; COPPER COMPLEXES; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; MECHANISM OF ACTION; REDOX-ACTIVE IRON; STRESS RESPONSE; THIOSEMICARBAZONES;

CELL DEATH;

CASPASE 3; CASPASE 7; CHELATING AGENT; DEFEROXAMINE; DI 2 PYRIDYLKETONE 4,4 DIMETHYL 3 THIOSEMICARBAZONE; MEMBRANE PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME REPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HOMEOSTASIS; HUMAN; HUMAN CELL; IRON CHELATION; IRON DEPLETION; METASTASIS; N MYC DOWNSTREAM REGULATED GENE 1; NDRG1 GENE; ONCOGENE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

DESFERRIOXAMINE; DP44MT; IRON; IRON CHELATORS; IRON METABOLISM; IRON-PROTEIN INTERACTIONS; LIGAND-METAL INTERACTIONS; METASTASIS; OXIDATIVE STRESS; STRESS;

AUTOPHAGY; CELL CYCLE PROTEINS; CELL LINE, TUMOR; COPPER; DEFEROXAMINE; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IRON; IRON CHELATING AGENTS; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; THIOSEMICARBAZONES;

EID: 84898065350     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.529511     Document Type: Article

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