Phase II study of Triapine® in patients with metastatic renal cell carcinoma: A trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)

Investigational New Drugs

Volumn 25, Issue 5, 2007, Pages 471-477

  Knox, Jennifer J ^a   Hotte, Sebastien J ^b   Kollmannsberger, Christian ^c   Winquist, Eric ^d   Fisher, Bryn ^e   Eisenhauer, Elizabeth A ^e  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b JURAVINSKI CANCER CENTRE   (Canada)

^c BRITISH COLUMBIA CANCER AGENCY   (Canada)

^d LONDON HEALTH SCIENCES CENTRE   (Canada)

^e QUEEN S UNIVERSITY   (Canada)

Author keywords

Kidney cancer; Phase II; Renal cell; Ribonucleotide reductase; Triapine

Indexed keywords

3 AMINOPICOLINALDEHYDE THIOSEMICARBAZONE; ANALGESIC AGENT; ERYTHROPOIETIN;

ADULT; AGED; ANOREXIA; ARTICLE; BICARBONATE BLOOD LEVEL; BLOOD TOXICITY; CANADA; CANCER RECURRENCE; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE COURSE; DIZZINESS; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG WITHDRAWAL; DRY SKIN; DYSPNEA; EDEMA; ESOPHAGITIS; EVALUATION; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; FEVER; FLUSHING; HEADACHE; HEALTH CARE ORGANIZATION; HEARTBURN; HUMAN; HYPERBILIRUBINEMIA; HYPERGLYCEMIA; HYPERKALEMIA; HYPOALBUMINEMIA; HYPOTENSION; HYPOXIA; INJECTION SITE REACTION; JAUNDICE; KIDNEY CARCINOMA; KIDNEY DYSFUNCTION; KIDNEY METASTASIS; MALE; METHEMOGLOBINEMIA; MUCOSA INFLAMMATION; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; MUSCLE WEAKNESS; MYALGIA; NAUSEA; NEUTROPENIA; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RIGOR; SENSORY NEUROPATHY; SIDE EFFECT; SWEATING; SYNCOPE; THORAX PAIN; TREATMENT RESPONSE; VOMITING;

AGED; ANTINEOPLASTIC AGENTS; CANADA; CARCINOMA, RENAL CELL; CLINICAL TRIALS; FEMALE; HUMANS; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; PYRIDINES; RIBONUCLEOTIDE REDUCTASES; THIOSEMICARBAZONES; TREATMENT OUTCOME;

EID: 34547687556     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-007-9044-9     Document Type: Article

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