-
1
-
-
29844457587
-
The evolution of iron chelators for the treatment of iron overload disease and cancer
-
Kalinowski DS and Richardson DR: The evolution of iron chelators for the treatment of iron overload disease and cancer. Pharmacol Rev 57: 547-583, 2005.
-
(2005)
Pharmacol Rev
, vol.57
, pp. 547-583
-
-
Kalinowski, D.S.1
Richardson, D.R.2
-
2
-
-
0017710272
-
Non-specific cytotoxicity of spleen cells in mice bearing transplanted chemically induced fibrosarcomas
-
Mantovani A, Evans R and Alexander P: Non-specific cytotoxicity of spleen cells in mice bearing transplanted chemically induced fibrosarcomas. Br J Cancer 36: 35-40, 1977.
-
(1977)
Br J Cancer
, vol.36
, pp. 35-40
-
-
Mantovani, A.1
Evans, R.2
Alexander, P.3
-
3
-
-
38949193907
-
Overexpression of cellular iron import proteins is associated with malignant progression of esophageal adenocarcinoma
-
Boult J, Roberts K, Brookes MJ, et al: Overexpression of cellular iron import proteins is associated with malignant progression of esophageal adenocarcinoma. Clin Cancer Res 14: 379-387, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 379-387
-
-
Boult, J.1
Roberts, K.2
Brookes, M.J.3
-
4
-
-
80155131215
-
An iron regulatory gene signature predicts outcome in breast cancer
-
Miller LD, Coffman LG, Chou JW, et al: An iron regulatory gene signature predicts outcome in breast cancer. Cancer Res 71: 6728-6737, 2011.
-
(2011)
Cancer Res
, vol.71
, pp. 6728-6737
-
-
Miller, L.D.1
Coffman, L.G.2
Chou, J.W.3
-
5
-
-
0022994492
-
Cancer chemotherapy induces a transient increase of serum-iron level
-
Follézou JY and Bizon M: Cancer chemotherapy induces a transient increase of serum-iron level. Neoplasma 33: 225-231, 1986.
-
(1986)
Neoplasma
, vol.33
, pp. 225-231
-
-
Follézou, J.Y.1
Bizon, M.2
-
6
-
-
84861898212
-
Iron chelators for the treatment of cancer
-
Yu Y, Gutierrez E, Kovacevic Z, et al: Iron chelators for the treatment of cancer. Curr Med Chem 19: 2689-2702, 2012.
-
(2012)
Curr Med Chem
, vol.19
, pp. 2689-2702
-
-
Yu, Y.1
Gutierrez, E.2
Kovacevic, Z.3
-
7
-
-
84866531103
-
Iron levels in polarized macrophages: Regulation of immunity and autoimmunity
-
Recalcati S, Locati M, Gammella E, Invernizzi P and Cairo G: Iron levels in polarized macrophages: regulation of immunity and autoimmunity. Autoimmun Rev 11: 883-889, 2012.
-
(2012)
Autoimmun Rev
, vol.11
, pp. 883-889
-
-
Recalcati, S.1
Locati, M.2
Gammella, E.3
Invernizzi, P.4
Cairo, G.5
-
8
-
-
59149091875
-
Metal ions stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1α protein
-
Kaczmarek M, Cachau RE, Topol IA, Kasprzak KS, Ghio A and Salnikow K: Metal ions stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1α protein. Toxicol Sci 107: 394-403, 2009.
-
(2009)
Toxicol Sci
, vol.107
, pp. 394-403
-
-
Kaczmarek, M.1
Cachau, R.E.2
Topol, I.A.3
Kasprzak, K.S.4
Ghio, A.5
Salnikow, K.6
-
9
-
-
49049106519
-
PARP-1 modulates deferoxamine-induced HIF-1α accumulation through the regulation of nitric oxide and oxidative stress
-
Martínez-Romero R, Martínez-Lara E, Aguilar-Quesada R, Peralta A, Oliver FJ and Siles E: PARP-1 modulates deferoxamine-induced HIF-1α accumulation through the regulation of nitric oxide and oxidative stress. J Cell Biochem 104: 2248-2260, 2008.
-
(2008)
J Cell Biochem
, vol.104
, pp. 2248-2260
-
-
Martínez-Romero, R.1
Martínez-Lara, E.2
Aguilar-Quesada, R.3
Peralta, A.4
Oliver, F.J.5
Siles, E.6
-
10
-
-
84875158140
-
HIFs, angiogenesis, and cancer
-
Yang Y, Sun M, Wang L and Jiao B: HIFs, angiogenesis, and cancer. J Cell Biochem 114: 967-974, 2013.
-
(2013)
J Cell Biochem
, vol.114
, pp. 967-974
-
-
Yang, Y.1
Sun, M.2
Wang, L.3
Jiao, B.4
-
11
-
-
56649099250
-
Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression
-
Simiantonaki N, Taxeidis M, Jayasinghe C, Kurzik-Dumke U and Kirkpatrick C: Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression. BMC Cancer 8: 320, 2008.
-
(2008)
BMC Cancer
, vol.8
, pp. 320
-
-
Simiantonaki, N.1
Taxeidis, M.2
Jayasinghe, C.3
Kurzik-Dumke, U.4
Kirkpatrick, C.5
-
12
-
-
0034021690
-
Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
-
Semenza GL: Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol 35: 71-103, 2000.
-
(2000)
Crit Rev Biochem Mol Biol
, vol.35
, pp. 71-103
-
-
Semenza, G.L.1
-
13
-
-
0038700554
-
Host microenvironment in breast cancer development: Epithelial- mesenchymal transition in breast cancer development
-
Vincent-Salomon A and Thiery JP: Host microenvironment in breast cancer development: epithelial-mesenchymal transition in breast cancer development. Breast Cancer Res 5: 101-106, 2003.
-
(2003)
Breast Cancer Res
, vol.5
, pp. 101-106
-
-
Vincent-Salomon, A.1
Thiery, J.P.2
-
14
-
-
77954380650
-
Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer
-
Zhang W, Jiang B, Guo Z, et al: Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer. Carcinogenesis 31: 1220-1229, 2010.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1220-1229
-
-
Zhang, W.1
Jiang, B.2
Guo, Z.3
-
15
-
-
78650417038
-
Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1
-
Zhang W, Wang J, Zou B, et al: Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1. Eur J Cancer 47: 121-130, 2011.
-
(2011)
Eur J Cancer
, vol.47
, pp. 121-130
-
-
Zhang, W.1
Wang, J.2
Zou, B.3
-
16
-
-
84875364615
-
Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas
-
Kahlert UD, Nikkhah G and Maciaczyk J: Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas. Cancer Lett 331: 131-138, 2013.
-
(2013)
Cancer Lett
, vol.331
, pp. 131-138
-
-
Kahlert, U.D.1
Nikkhah, G.2
Maciaczyk, J.3
-
17
-
-
84879091418
-
DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer
-
Roy N, Bommi PV, Bhat UG, et al: DDB2 suppresses epithelial-to- mesenchymal transition in colon cancer. Cancer Res 73: 3771-3782, 2013.
-
(2013)
Cancer Res
, vol.73
, pp. 3771-3782
-
-
Roy, N.1
Bommi, P.V.2
Bhat, U.G.3
-
18
-
-
36849021771
-
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
-
Higgins DF, Kimura K, Bernhardt WM, et al: Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest 117: 3810-3820, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 3810-3820
-
-
Higgins, D.F.1
Kimura, K.2
Bernhardt, W.M.3
-
19
-
-
79954579633
-
EMT: A new vision of hypoxia promoting cancer progression
-
Jiang J, Tang YL and Liang XH: EMT: a new vision of hypoxia promoting cancer progression. Cancer Biol Ther 11: 714-723, 2011.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 714-723
-
-
Jiang, J.1
Tang, Y.L.2
Liang, X.H.3
-
20
-
-
40249113328
-
Direct regulation of TWIST by HIF-1α promotes metastasis
-
Yang MH, Wu MZ, Chiou SH, et al: Direct regulation of TWIST by HIF-1α promotes metastasis. Nat Cell Biol 10: 295-305, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 295-305
-
-
Yang, M.H.1
Wu, M.Z.2
Chiou, S.H.3
-
21
-
-
84877157115
-
Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling
-
Zhang Q, Bai X, Chen W, et al: Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling. Carcinogenesis 34: 962-973, 2013.
-
(2013)
Carcinogenesis
, vol.34
, pp. 962-973
-
-
Zhang, Q.1
Bai, X.2
Chen, W.3
-
22
-
-
33947321597
-
Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis
-
Wang J, Yang Y, Xia HH, et al: Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis. Gastroenterology 132: 1066-1076, 2007.
-
(2007)
Gastroenterology
, vol.132
, pp. 1066-1076
-
-
Wang, J.1
Yang, Y.2
Xia, H.H.3
-
23
-
-
84874647804
-
Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer
-
Hollestelle A, Peeters JK, Smid M, et al: Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer. Breast Cancer Res Treat 138: 47-57, 2013.
-
(2013)
Breast Cancer Res Treat
, vol.138
, pp. 47-57
-
-
Hollestelle, A.1
Peeters, J.K.2
Smid, M.3
-
24
-
-
0026548223
-
Tumor cell adhesion to the extracellular matrix and signal transduction mechanisms implicated in tumor cell motility, invasion and metastasis
-
Lester BR and McCarthy JB: Tumor cell adhesion to the extracellular matrix and signal transduction mechanisms implicated in tumor cell motility, invasion and metastasis. Cancer Metastasis Rev 11: 31-44, 1992.
-
(1992)
Cancer Metastasis Rev
, vol.11
, pp. 31-44
-
-
Lester, B.R.1
McCarthy, J.B.2
-
25
-
-
0027933266
-
Transformation and tumor progression are frequently associated with expression of the alpha 3/beta 1 heterodimer in solid tumors
-
Bartolazzi A, Cerboni C, Nicotra MR, Mottolese M, Bigotti A and Natali PG: Transformation and tumor progression are frequently associated with expression of the alpha 3/beta 1 heterodimer in solid tumors. Int J Cancer 58: 488-491, 1994.
-
(1994)
Int J Cancer
, vol.58
, pp. 488-491
-
-
Bartolazzi, A.1
Cerboni, C.2
Nicotra, M.R.3
Mottolese, M.4
Bigotti, A.5
Natali, P.G.6
-
26
-
-
10944223361
-
Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis
-
Wei L, Yang Y, Zhang X and Yu Q: Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis. Oncogene 23: 9052-9061, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 9052-9061
-
-
Wei, L.1
Yang, Y.2
Zhang, X.3
Yu, Q.4
-
27
-
-
84874436167
-
Overexpression of HIF-1α indicates a poor prognosis in tongue carcinoma and may be associated with tumour metastasis
-
Zheng Y, Ni Y, Huang X, Wang Z and Han W: Overexpression of HIF-1α indicates a poor prognosis in tongue carcinoma and may be associated with tumour metastasis. Oncol Lett 5: 1285-1289, 2013.
-
(2013)
Oncol Lett
, vol.5
, pp. 1285-1289
-
-
Zheng, Y.1
Ni, Y.2
Huang, X.3
Wang, Z.4
Han, W.5
-
28
-
-
84861378912
-
Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells
-
Cheli Y, Giuliano S, Fenouille N, et al: Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells. Oncogene 31: 2461-2470, 2012.
-
(2012)
Oncogene
, vol.31
, pp. 2461-2470
-
-
Cheli, Y.1
Giuliano, S.2
Fenouille, N.3
-
29
-
-
77956400210
-
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment
-
Martinez-Outschoorn UE, Trimmer C, Lin Z, et al: Autophagy in cancer associated fibroblasts promotes tumor cell survival: role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment. Cell Cycle 9: 3515-3533, 2010.
-
(2010)
Cell Cycle
, vol.9
, pp. 3515-3533
-
-
Martinez-Outschoorn, U.E.1
Trimmer, C.2
Lin, Z.3
-
30
-
-
84875698523
-
Angiogenesis and hypoxia in the kidney
-
Tanaka T and Nangaku M: Angiogenesis and hypoxia in the kidney. Nat Rev Nephrol 9: 211-222, 2013.
-
(2013)
Nat Rev Nephrol
, vol.9
, pp. 211-222
-
-
Tanaka, T.1
Nangaku, M.2
-
31
-
-
0034647933
-
Antioxidant/pro-oxidant equilibrium regulates HIF-1α and NF-κB redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells
-
Haddad JJ, Olver RE and Land SC: Antioxidant/pro-oxidant equilibrium regulates HIF-1α and NF-κB redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells. J Biol Chem 275: 21130-21139, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 21130-21139
-
-
Haddad, J.J.1
Olver, R.E.2
Land, S.C.3
-
32
-
-
68549106083
-
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
-
Schmalhofer O, Brabletz S and Brabletz T: E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev 28: 151-166, 2009.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 151-166
-
-
Schmalhofer, O.1
Brabletz, S.2
Brabletz, T.3
|