Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers

Biochemical Journal

Volumn 462, Issue 3, 2014, Pages 397-413

  Eguchi, Asuka ^a   Lee, Garrett O ^a   Wan, Fang ^a   Erwin, Graham S ^a   Ansari, Aseem Z ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Artificial transcription factor; Cell fate; Genome editing; Reprogramming; Synthetic biology

Indexed keywords

DNA; DNA BINDING PROTEIN; HISTONE DEACETYLASE; HISTONE METHYLTRANSFERASE; IMMUNOGLOBULIN; INTERCELLULAR ADHESION MOLECULE 1; NUCLEASE; PEPTIDE NUCLEIC ACID; POLYAMIDE; TRANSCRIPTION FACTOR; VASCULOTROPIN; ZINC FINGER PROTEIN;

CELL FATE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA BINDING; ENHANCER REGION; GENE ACTIVATION; GENE LIBRARY; GENE REGULATORY NETWORK; GENE REPRESSION; GENE TARGETING; GENETIC ENGINEERING; GENETIC REGULATION; GENETIC SCREENING; GENETIC TRANSCRIPTION; HUMAN; MUTAGENESIS; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN TARGETING; REGULATOR GENE; REVIEW; TRANSCRIPTION REGULATION;

CRISPR-ASSOCIATED PROTEINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; NYLONS; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 84907337833     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140400     Document Type: Review

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