Heterodimeric DNA methyltransferases as a platform for creating designer zinc finger methyltransferases for targeted DNA methylation in cells

Nucleic Acids Research

Volumn 38, Issue 5, 2009, Pages 1749-1759

  Meister, Glenna E ^a   Chandrasegaran, Srinivasan ^b   Ostermeier, Marc ^a  

^a Johns Hopkins University   (United States)

^b The Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DNA; DNA METHYLTRANSFERASE; HETERODIMER; ZINC FINGER PROTEIN; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA MODIFICATION METHYLASE ECOHK31I; HYBRID PROTEIN;

ARTICLE; BASE PAIRING; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; DNA METHYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; CHEMISTRY; DIMERIZATION; DNA SEQUENCE; ENZYME SPECIFICITY; GENE DELETION; GENE DOSAGE; GENETICS; METABOLISM; PROTEIN ENGINEERING;

ESCHERICHIA COLI;

BINDING SITES; DIMERIZATION; DNA METHYLATION; DNA-CYTOSINE METHYLASES; GENE DOSAGE; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; SUBSTRATE SPECIFICITY; ZINC FINGERS;

EID: 77950495366     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp1126     Document Type: Article

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