Zinc-finger nucleases for somatic gene therapy: The next frontier

Human Gene Therapy

Volumn 22, Issue 8, 2011, Pages 925-933

  Rahman, Shamim H ^a   Maeder, Morgan L ^b,c   Joung, J Keith ^b,c,d   Cathomen, Toni ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c Biological and Biomedical Sciences Program   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; CHEMOKINE RECEPTOR CCR5; COMPLEMENTARY DNA; ERYTHROPOIETIN; INTERLEUKIN 2 RECEPTOR; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE; ZINC FINGER PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADAPTIVE IMMUNITY; BINDING AFFINITY; CELL SURVIVAL; DNA CLEAVAGE; DNA DAMAGE; DRUG DNA BINDING; DRUG MECHANISM; DRUG SPECIFICITY; GENE DISRUPTION; GENE LOCUS; GENE MUTATION; GENE TARGETING; GENETIC ENGINEERING; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LEUKEMIA; LYMPHOCYTE; MESENCHYMAL STROMAL CELL; MESENCHYME CELL; NATURAL KILLER CELL; NONHUMAN; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PLURIPOTENT STEM CELL; PROTEIN FUNCTION; PROTO ONCOGENE; REVIEW; RISK ASSESSMENT; SOMATIC GENE THERAPY; STEM CELL; T LYMPHOCYTE;

ENDONUCLEASES; GENE THERAPY; GENETIC ENGINEERING; GENOME, HUMAN; HIV INFECTIONS; HUMANS; RECEPTORS, CCR5; ZINC FINGERS;

EID: 80051987044     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2011.087     Document Type: Review

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