Generation of isogenic pluripotent stem cells differing exclusively at two early onset parkinson point mutations

Cell

Volumn 146, Issue 2, 2011, Pages 318-331

  Soldner, Frank ^a   Laganière, Josée ^c   Cheng, Albert W ^a,b   Hockemeyer, Dirk ^a   Gao, Qing ^a   Alagappan, Raaji ^a   Khurana, Vikram ^a,d   Golbe, Lawrence I ^f   Myers, Richard H ^e   Lindquist, Susan ^a,b   Zhang, Lei ^c   Guschin, Dmitry ^c   Fong, Lauren K ^c   Vu, B Joseph ^c   Meng, Xiangdong ^c   Urnov, Fyodor D ^c   Rebar, Edward J ^c   Gregory, Philip D ^c   Zhang, H Steve ^c   Jaenisch, Rudolf ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c SANGAMO BIOSCIENCES INC   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; NUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE; ZINC FINGER PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DISEASE COURSE; EMBRYO; EMBRYONIC STEM CELL; GENE INSERTION; GENETIC ENGINEERING; GENETIC SUSCEPTIBILITY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PLURIPOTENT STEM CELL; POINT MUTATION; PRIORITY JOURNAL; WILD TYPE;

EID: 79960833952     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.06.019     Document Type: Article

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