Rapid "Open-Source" Engineering of Customized Zinc-Finger Nucleases for Highly Efficient Gene Modification

Molecular Cell

Volumn 31, Issue 2, 2008, Pages 294-301

  Maeder, Morgan L ^a   Thibodeau Beganny, Stacey ^a   Osiak, Anna ^b   Wright, David A ^c   Anthony, Reshma M ^d   Eichtinger, Magdalena ^a,e   Jiang, Tao ^a,e   Foley, Jonathan E ^a   Winfrey, Ronnie J ^c   Townsend, Jeffrey A ^c   Unger Wallace, Erica ^c   Sander, Jeffry D ^c   Müller Lerch, Felix ^b   Fu, Fengli ^c   Pearlberg, Joseph ^e   Göbel, Carl ^a   Dassie, Justin P ^d   Pruett Miller, Shondra M ^f   Porteus, Matthew H ^f   Sgroi, Dennis C ^a,e   Iafrate, A John ^a,e   Dobbs, Drena ^c   McCray Jr , Paul B ^d   Cathomen, Toni ^b   Voytas, Daniel F ^c   Joung, J Keith ^a,e   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c IOWA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF IOWA   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

DNA

Indexed keywords

NUCLEASE; TRANSMEMBRANE CONDUCTANCE REGULATOR; VASCULOTROPIN A; ZINC FINGER NUCLEASE;

ARTICLE; BIOLOGY; CAENORHABDITIS ELEGANS; CFTR GENE; DROSOPHILA; GENE; GENE THERAPY; GENETIC DATABASE; GENETIC ENGINEERING; HOXB13 GENE; HUMAN; HUMAN CELL; NONHUMAN; REPORTER GENE; SURA GENE; VEGF A GENE; ZINC FINGER MOTIF;

BASE SEQUENCE; ENDONUCLEASES; GENE TARGETING; GENETIC ENGINEERING; GREEN FLUORESCENT PROTEINS; HUMANS; K562 CELLS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; PROTEIN CONFORMATION; ZINC FINGERS;

CAENORHABDITIS ELEGANS; NICOTIANA TABACUM;

EID: 47349097567     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2008.06.016     Document Type: Article

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