메뉴 건너뛰기




Volumn 25, Issue 20, 2005, Pages 9082-9091

Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: Insights into ErbB receptor biology

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; INTERCELLULAR ADHESION MOLECULE 1; LAMININ; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR; TYROSINE KINASE RECEPTOR; ZINC FINGER PROTEIN;

EID: 26444464763     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.20.9082-9091.2005     Document Type: Article
Times cited : (18)

References (84)
  • 1
    • 0032586952 scopus 로고    scopus 로고
    • Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase
    • Adelsman, M. A., J. B. McCarthy, and Y. Shimizu. 1999. Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase. Mol. Biol. Cell 10:2861-2878.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2861-2878
    • Adelsman, M.A.1    McCarthy, J.B.2    Shimizu, Y.3
  • 2
    • 0035912086 scopus 로고    scopus 로고
    • Expression of a truncated 100 kDa HER2 splice variant acts as an endogenous inhibitor of tumour cell proliferation
    • Aigner, A., H. Juhl, C. Malerczyk, A. Tkybusch, C. C. Benz, and F. Czubayko. 2001. Expression of a truncated 100 kDa HER2 splice variant acts as an endogenous inhibitor of tumour cell proliferation. Oncogene 20:2101-2111.
    • (2001) Oncogene , vol.20 , pp. 2101-2111
    • Aigner, A.1    Juhl, H.2    Malerczyk, C.3    Tkybusch, A.4    Benz, C.C.5    Czubayko, F.6
  • 3
    • 0141645488 scopus 로고    scopus 로고
    • Mechanism of action of anti-HER2 monoclonal antibodies: Scientific update on trastuzumab and 2C4
    • Albanell, J., J. Codony, A. Rovira, B. Mellado, and P. Gascon. 2003. Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4. Adv. Exp. Med. Biol. 532:253-268.
    • (2003) Adv. Exp. Med. Biol. , vol.532 , pp. 253-268
    • Albanell, J.1    Codony, J.2    Rovira, A.3    Mellado, B.4    Gascon, P.5
  • 4
    • 0034699249 scopus 로고    scopus 로고
    • Activation of the alpha2beta1 integrin prevents c-erbB2-induced scattering and apoptosis of human mammary epithelial cells in collagen
    • Baeckstrom, D., P. J. Lu, and J. Taylor-Papadimitriou. 2000. Activation of the alpha2beta1 integrin prevents c-erbB2-induced scattering and apoptosis of human mammary epithelial cells in collagen. Oncogene 19:4592-4603.
    • (2000) Oncogene , vol.19 , pp. 4592-4603
    • Baeckstrom, D.1    Lu, P.J.2    Taylor-Papadimitriou, J.3
  • 6
    • 0029912203 scopus 로고    scopus 로고
    • All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired
    • Baulida, J., M. H. Kraus, M. Alimandi, P. P. Di Fiore, and G. Carpenter. 1996. All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J. Biol. Chem. 271:5251-5257.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5251-5257
    • Baulida, J.1    Kraus, M.H.2    Alimandi, M.3    Di Fiore, P.P.4    Carpenter, G.5
  • 7
    • 0036168937 scopus 로고    scopus 로고
    • Engineering polydactyl zinc-finger transcription factors
    • Beerli, R. R., and C. F. Barbas III. 2002. Engineering polydactyl zinc-finger transcription factors. Nat. Biotechnol. 20:135-141.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 135-141
    • Beerli, R.R.1    Barbas III, C.F.2
  • 8
    • 0034652141 scopus 로고    scopus 로고
    • Positive and negative regulation of endogenous genes by designed transcription factors
    • Beerli, R. R., B. Dreier, and C. F. Barbas III. 2000. Positive and negative regulation of endogenous genes by designed transcription factors. Proc. Natl. Acad. Sci. USA 97:1495-1500.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1495-1500
    • Beerli, R.R.1    Dreier, B.2    Barbas III, C.F.3
  • 9
    • 0032437591 scopus 로고    scopus 로고
    • Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
    • Beerli, R. R., D. J. Segal, B. Dreier, and C. F. Barbas III. 1998. Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks. Proc. Natl. Acad. Sci. USA 95:14628-14633.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 14628-14633
    • Beerli, R.R.1    Segal, D.J.2    Dreier, B.3    Barbas III, C.F.4
  • 10
    • 9444230573 scopus 로고    scopus 로고
    • Designing transcription factor architectures for drug discovery
    • Blancafort, P., D. J. Segal, and C. F. Barbas III. 2004. Designing transcription factor architectures for drug discovery. Mol. Pharmacol. 66:1361-1371.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 1361-1371
    • Blancafort, P.1    Segal, D.J.2    Barbas III, C.F.3
  • 11
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen, P., and T. Hunter. 2001. Oncogenic kinase signalling. Nature 411:355-365.
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 13
    • 9444283156 scopus 로고    scopus 로고
    • RNA interference: Past, present and future
    • Campbell, T. N., and F. Y. Choy. 2005. RNA interference: past, present and future. Curr. Issues Mol. Biol. 7:1-6.
    • (2005) Curr. Issues Mol. Biol. , vol.7 , pp. 1-6
    • Campbell, T.N.1    Choy, F.Y.2
  • 14
    • 17844386569 scopus 로고    scopus 로고
    • Monoclonal antibodies targeting epidermal growth factor receptor and vascular endothelial growth factor with a focus on head and neck tumors
    • Caponigro, F., R. Formato, M. Caraglia, N. Normanno, and R. V. Iaffaioli. 2005. Monoclonal antibodies targeting epidermal growth factor receptor and vascular endothelial growth factor with a focus on head and neck tumors. Curr. Opin. Oncol. 17:212-217.
    • (2005) Curr. Opin. Oncol. , vol.17 , pp. 212-217
    • Caponigro, F.1    Formato, R.2    Caraglia, M.3    Normanno, N.4    Iaffaioli, R.V.5
  • 15
    • 3442890204 scopus 로고    scopus 로고
    • Role of HER receptors family in development and differentiation
    • Casalini, P., M. V. Iorio, E. Galmozzi, and S. Menard. 2004. Role of HER receptors family in development and differentiation. J. Cell. Physiol: 200:343-350.
    • (2004) J. Cell. Physiol. , vol.200 , pp. 343-350
    • Casalini, P.1    Iorio, M.V.2    Galmozzi, E.3    Menard, S.4
  • 16
    • 0034677568 scopus 로고    scopus 로고
    • Molecular requirements for the effect of neuregulin on cell spreading, motility and colony organization
    • Chausovsky, A., H. Waterman, M. Elbaum, Y. Yarden, B. Geiger, and A. D. Bershadsky. 2000. Molecular requirements for the effect of neuregulin on cell spreading, motility and colony organization. Oncogene 19:878-888.
    • (2000) Oncogene , vol.19 , pp. 878-888
    • Chausovsky, A.1    Waterman, H.2    Elbaum, M.3    Yarden, Y.4    Geiger, B.5    Bershadsky, A.D.6
  • 17
    • 0041923790 scopus 로고    scopus 로고
    • Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3
    • Chen, C. H., G. A. Chernis, V. Q. Hoang, and R. Landgraf. 2003. Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3. Proc. Natl. Acad. Sci. USA 100:9226-9231.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9226-9231
    • Chen, C.H.1    Chernis, G.A.2    Hoang, V.Q.3    Landgraf, R.4
  • 18
  • 19
    • 11244257032 scopus 로고    scopus 로고
    • The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer
    • Chu, I., K. Blackwell, S. Chen, and J. Slingerland. 2005. The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer. Cancer Res. 65:18-25.
    • (2005) Cancer Res. , vol.65 , pp. 18-25
    • Chu, I.1    Blackwell, K.2    Chen, S.3    Slingerland, J.4
  • 20
    • 0027204277 scopus 로고
    • Collagen-induced morphogenesis and expression of the alpha 2-integrin subunit is inhibited in c-erbB2-transfected human mammary epithelial cells
    • D'Souza, B., F. Berdichevsky, N. Kyprianou, and J. Taylor-Papadimitriou. 1993. Collagen-induced morphogenesis and expression of the alpha 2-integrin subunit is inhibited in c-erbB2-transfected human mammary epithelial cells. Oncogene 8:1797-1806.
    • (1993) Oncogene , vol.8 , pp. 1797-1806
    • D'Souza, B.1    Berdichevsky, F.2    Kyprianou, N.3    Taylor-Papadimitriou, J.4
  • 21
    • 0036146820 scopus 로고    scopus 로고
    • Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection
    • Eicheler, W., D. Zips, A. Dorfler, R. Grenman, and M. Baumann. 2002. Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection. J. Histochem. Cytochem. 50:197-204.
    • (2002) J. Histochem. Cytochem. , vol.50 , pp. 197-204
    • Eicheler, W.1    Zips, D.2    Dorfler, A.3    Grenman, R.4    Baumann, M.5
  • 23
    • 0028120910 scopus 로고
    • Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members
    • Fedi, P., J. H. Pierce, P. P. di Fiore, and M. H. Kraus. 1994. Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members. Mol. Cell. Biol. 14:492-500.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 492-500
    • Fedi, P.1    Pierce, J.H.2    Di Fiore, P.P.3    Kraus, M.H.4
  • 25
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • Graus-Porta, D., R. R. Beerli, J. M. Daly, and N. E. Hynes. 1997. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J. 16:1647-1655.
    • (1997) EMBO J. , vol.16 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 26
    • 0028893444 scopus 로고
    • Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling
    • Graus-Porta, D., R. R. Beerli, and N. E. Hynes. 1995. Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling. Mol. Cell. Biol. 15:1182-1191.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1182-1191
    • Graus-Porta, D.1    Beerli, R.R.2    Hynes, N.E.3
  • 27
    • 2142700147 scopus 로고    scopus 로고
    • Targeting the HER-kinase axis in cancer
    • Gross, M. E., R. L. Shazer, and D. B. Agus. 2004. Targeting the HER-kinase axis in cancer. Semin. Oncol. 31:9-20.
    • (2004) Semin. Oncol. , vol.31 , pp. 9-20
    • Gross, M.E.1    Shazer, R.L.2    Agus, D.B.3
  • 28
    • 0034235628 scopus 로고    scopus 로고
    • The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors
    • Hansen, L. A., R. L. Woodson II, S. Holbus, K. Strain, Y. C. Lo, and S. H. Yuspa. 2000. The epidermal growth factor receptor is required to maintain the proliferative population in the basal compartment of epidermal tumors. Cancer Res. 60:3328-3332.
    • (2000) Cancer Res. , vol.60 , pp. 3328-3332
    • Hansen, L.A.1    Woodson II, R.L.2    Holbus, S.3    Strain, K.4    Lo, Y.C.5    Yuspa, S.H.6
  • 29
    • 0034638925 scopus 로고    scopus 로고
    • Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
    • Harari, D., and Y. Yarden. 2000. Molecular mechanisms underlying ErbB2/HER2 action in breast cancer. Oncogene 19:6102-6114.
    • (2000) Oncogene , vol.19 , pp. 6102-6114
    • Harari, D.1    Yarden, Y.2
  • 30
  • 31
    • 0035972158 scopus 로고    scopus 로고
    • Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin
    • Hintermann, E., M. Bilban, A. Sharabi, and V. Quaranta. 2001. Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin. J. Cell Biol. 153:465-478.
    • (2001) J. Cell Biol. , vol.153 , pp. 465-478
    • Hintermann, E.1    Bilban, M.2    Sharabi, A.3    Quaranta, V.4
  • 32
    • 3042749811 scopus 로고    scopus 로고
    • Epithelial cell motility on laminin-5: Regulation by matrix assembly, proteolysis, integrins and erbB receptors
    • Hintermann, E., and V. Quaranta. 2004. Epithelial cell motility on laminin-5: regulation by matrix assembly, proteolysis, integrins and erbB receptors. Matrix Biol. 23:75-85.
    • (2004) Matrix Biol. , vol.23 , pp. 75-85
    • Hintermann, E.1    Quaranta, V.2
  • 33
    • 0042307325 scopus 로고    scopus 로고
    • The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
    • Holbro, T., R. R. Beerli, F. Maurer, M. Koziczak, C. F. Barbas III, and N. E. Hynes. 2003. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc. Natl. Acad. Sci. USA 100:8933-8938.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8933-8938
    • Holbro, T.1    Beerli, R.R.2    Maurer, F.3    Koziczak, M.4    Barbas III, C.F.5    Hynes, N.E.6
  • 34
    • 1342323632 scopus 로고    scopus 로고
    • ErbB receptors: Directing key signaling networks throughout life
    • Holbro, T., and N. E. Hynes. 2004. ErbB receptors: directing key signaling networks throughout life. Annu. Rev. Pharmacol. Toxicol. 44:195-217.
    • (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 35
    • 0041322734 scopus 로고    scopus 로고
    • Co-expression of ErbB-family members in human breast cancer: Her-2/neu is the preferred dimerization candidate in nodal-positive tumors
    • Hudelist, G., C. F. Singer, M. Manavi, K. Pischinger, E. Kubista, and K. Czerwenka. 2003. Co-expression of ErbB-family members in human breast cancer: Her-2/neu is the preferred dimerization candidate in nodal-positive tumors. Breast Cancer Res. Treat. 80:353-361.
    • (2003) Breast Cancer Res. Treat. , vol.80 , pp. 353-361
    • Hudelist, G.1    Singer, C.F.2    Manavi, M.3    Pischinger, K.4    Kubista, E.5    Czerwenka, K.6
  • 36
    • 0033009389 scopus 로고    scopus 로고
    • Binding specificities and affinities of egf domains for ErbB receptors
    • Jones, J. T., R. W. Akita, and M. X. Sliwkowski. 1999. Binding specificities and affinities of egf domains for ErbB receptors. FEBS Lett. 447:227-231.
    • (1999) FEBS Lett. , vol.447 , pp. 227-231
    • Jones, J.T.1    Akita, R.W.2    Sliwkowski, M.X.3
  • 38
    • 0035995647 scopus 로고    scopus 로고
    • EGF and beta1 integrin convergently regulate migration of A431 carcinoma cell through MAP kinase activation
    • Kawahara, E., N. Nakada, T. Hikichi, J. Kobayashi, and I. Nakanishi. 2002. EGF and beta1 integrin convergently regulate migration of A431 carcinoma cell through MAP kinase activation. Exp. Cell Res. 272:84-91.
    • (2002) Exp. Cell Res. , vol.272 , pp. 84-91
    • Kawahara, E.1    Nakada, N.2    Hikichi, T.3    Kobayashi, J.4    Nakanishi, I.5
  • 39
    • 0346433892 scopus 로고    scopus 로고
    • RNA interference in functional genomics and medicine
    • Kim, V. N. 2003. RNA interference in functional genomics and medicine. J. Korean Med. Sci. 18:309-318.
    • (2003) J. Korean Med. Sci. , vol.18 , pp. 309-318
    • Kim, V.N.1
  • 40
    • 0141787069 scopus 로고    scopus 로고
    • Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone
    • Klos, K. S., X. Zhou, S. Lee, L. Zhang, W. Yang, Y. Nagata, and D. Yu. 2003. Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone. Cancer 98:1377-1385.
    • (2003) Cancer , vol.98 , pp. 1377-1385
    • Klos, K.S.1    Zhou, X.2    Lee, S.3    Zhang, L.4    Yang, W.5    Nagata, Y.6    Yu, D.7
  • 41
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • Kraus, M. H., W. Issing, T. Miki, N. C. Popescu, and S. A. Aaronson. 1989. Isolation and characterization of ERBB3, a third member of the ERBB/ epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc. Natl. Acad. Sci. USA 86:9193-9197.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 42
    • 3442879850 scopus 로고    scopus 로고
    • Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways
    • Lee, J. W., and R. Juliano. 2004. Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways. Mol. Cell 17:188-202.
    • (2004) Mol. Cell , vol.17 , pp. 188-202
    • Lee, J.W.1    Juliano, R.2
  • 44
    • 0035711333 scopus 로고    scopus 로고
    • The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics
    • Lorens, J. B., C. Sousa, M. K. Bennett, S. M. Molineaux, and D. G. Payan. 2001. The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics. Curr. Opin. Biotechnol. 12:613-621.
    • (2001) Curr. Opin. Biotechnol. , vol.12 , pp. 613-621
    • Lorens, J.B.1    Sousa, C.2    Bennett, M.K.3    Molineaux, S.M.4    Payan, D.G.5
  • 45
    • 2942744633 scopus 로고    scopus 로고
    • Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation
    • Lund, C. V., P. Blancafort, M. Popkov, and C. F. Barbas III. 2004. Promoter-targeted phage display selections with preassembled synthetic zinc finger libraries for endogenous gene regulation. J. Mol. Biol. 340:599-613.
    • (2004) J. Mol. Biol. , vol.340 , pp. 599-613
    • Lund, C.V.1    Blancafort, P.2    Popkov, M.3    Barbas III, C.F.4
  • 46
    • 4344685148 scopus 로고    scopus 로고
    • In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation
    • Magnenat, L., P. Blancafort, and C. F. Barbas III. 2004. In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation. J. Mol. Biol. 341:635-649.
    • (2004) J. Mol. Biol. , vol.341 , pp. 635-649
    • Magnenat, L.1    Blancafort, P.2    Barbas III, C.F.3
  • 49
    • 0037446068 scopus 로고    scopus 로고
    • Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB 1) and induce apoptosis in erbB1-overexpressing cells
    • Nagy, P., D. J. Arndt-Jovin, and T. M. Jovin. 2003. Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB 1) and induce apoptosis in erbB1-overexpressing cells. Exp. Cell Res. 285:39-49.
    • (2003) Exp. Cell Res. , vol.285 , pp. 39-49
    • Nagy, P.1    Arndt-Jovin, D.J.2    Jovin, T.M.3
  • 50
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • Nicholson, K. M., and N. G. Anderson. 2002. The protein kinase B/Akt signalling pathway in human malignancy. Cell. Signal. 14:381-395.
    • (2002) Cell. Signal. , vol.14 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2
  • 51
    • 2342488965 scopus 로고    scopus 로고
    • Update on HER-2 as a target for cancer therapy: Intracellular signaling pathways of ErbB2/HER-2 and family members
    • Olayioye, M. A. 2001. Update on HER-2 as a target for cancer therapy: intracellular signaling pathways of ErbB2/HER-2 and family members. Breast Cancer Res. 3:385-389.
    • (2001) Breast Cancer Res. , vol.3 , pp. 385-389
    • Olayioye, M.A.1
  • 52
    • 0031840484 scopus 로고    scopus 로고
    • ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner
    • Olayioye, M. A., D. Graus-Porta, R. R. Beerli, J. Rohrer, B. Gay, and N. E. Hynes. 1998. ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner. Mol. Cell. Biol. 18:5042-5051.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5042-5051
    • Olayioye, M.A.1    Graus-Porta, D.2    Beerli, R.R.3    Rohrer, J.4    Gay, B.5    Hynes, N.E.6
  • 53
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye, M. A., R. M. Neve, H. A. Lane, and N. E. Hynes. 2000. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J. 19:3159-3167.
    • (2000) EMBO J. , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 54
    • 0034787428 scopus 로고    scopus 로고
    • Extracellular matrix and keratinocyte migration
    • O'Toole, E. A. 2001. Extracellular matrix and keratinocyte migration. Clin. Exp. Dermatol. 26:525-530.
    • (2001) Clin. Exp. Dermatol. , vol.26 , pp. 525-530
    • O'Toole, E.A.1
  • 55
    • 0035989898 scopus 로고    scopus 로고
    • Constitutively active ErbB4 and ErbB2 mutants exhibit distinct biological activities
    • Penington, D. J., I. Bryant, and D. J. Riese II. 2002. Constitutively active ErbB4 and ErbB2 mutants exhibit distinct biological activities. Cell Growth Differ. 13:247-256.
    • (2002) Cell Growth Differ. , vol.13 , pp. 247-256
    • Penington, D.J.1    Bryant, I.2    Riese II, D.J.3
  • 58
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
    • Roux, P. P., and J. Blenis. 2004. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68:320-344.
    • (2004) Microbiol. Mol. Biol. Rev. , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 59
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon, D. S., R. Brandt, F. Ciardiello, and N. Normanno. 1995. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol. 19:183-232.
    • (1995) Crit. Rev. Oncol. Hematol. , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 61
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger, J. 2000. Cell signaling by receptor tyrosine kinases. Cell 103:211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 64
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon, D. J., G. M. Clark, S. G. Wong, W. J. Levin, A. Ullrich, and W. L. McGuire. 1987. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235:177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 65
    • 0034707581 scopus 로고    scopus 로고
    • ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases
    • Spencer, K. S., D. Graus-Porta, J. Leng, N. E. Hynes, and R. L. Klemke. 2000. ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases. J. Cell Biol. 148:385-397.
    • (2000) J. Cell Biol. , vol.148 , pp. 385-397
    • Spencer, K.S.1    Graus-Porta, D.2    Leng, J.3    Hynes, N.E.4    Klemke, R.L.5
  • 69
    • 18644365247 scopus 로고    scopus 로고
    • The evolution of predictive oncology and molecular-based therapy for oral cancer prevention
    • Sudbo, J., and A. Reith. 2005. The evolution of predictive oncology and molecular-based therapy for oral cancer prevention. Int. J. Cancer 115:339-345.
    • (2005) Int. J. Cancer , vol.115 , pp. 339-345
    • Sudbo, J.1    Reith, A.2
  • 71
    • 0034693801 scopus 로고    scopus 로고
    • Ligand discrimination by ErbB receptors: Differential signaling through differential phosphorylation site usage
    • Sweeney, C., and K. L. Carraway III. 2000. Ligand discrimination by ErbB receptors: differential signaling through differential phosphorylation site usage. Oncogene 19:5568-5573.
    • (2000) Oncogene , vol.19 , pp. 5568-5573
    • Sweeney, C.1    Carraway III, K.L.2
  • 73
    • 0034666345 scopus 로고    scopus 로고
    • Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): A study of incidence and correlation with outcome in breast cancer
    • Thor, A. D., S. Liu, S. Edgerton, D. Moore II, K. M. Kasowitz, C. C. Benz, D. F. Stern, and M. P. DiGiovanna. 2000. Activation (tyrosine phosphorylation) of ErbB-2 (HER-2/neu): a study of incidence and correlation with outcome in breast cancer. J. Clin. Oncol. 18:3230-3239.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3230-3239
    • Thor, A.D.1    Liu, S.2    Edgerton, S.3    Moore II, D.4    Kasowitz, K.M.5    Benz, C.C.6    Stern, D.F.7    DiGiovanna, M.P.8
  • 74
    • 3142773290 scopus 로고    scopus 로고
    • Outcome and human epidermal growth factor receptor (HER) 1-4 status in invasive breast carcinomas with proliferation indices evaluated by bromodeoxyuridine labelling
    • Tovey, S. M., C. J. Witton, J. M. Bartlett, P. D. Stanton, J. R. Reeves, and T. G. Cooke. 2004. Outcome and human epidermal growth factor receptor (HER) 1-4 status in invasive breast carcinomas with proliferation indices evaluated by bromodeoxyuridine labelling. Breast Cancer Res. 6:R246-R251.
    • (2004) Breast Cancer Res. , vol.6
    • Tovey, S.M.1    Witton, C.J.2    Bartlett, J.M.3    Stanton, P.D.4    Reeves, J.R.5    Cooke, T.G.6
  • 75
    • 0037421965 scopus 로고    scopus 로고
    • Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer
    • Tsai, M. S., L. A. Shamon-Taylor, I. Mehmi, C. K. Tang, and R. Lupu. 2003. Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer. Oncogene 22:761-768.
    • (2003) Oncogene , vol.22 , pp. 761-768
    • Tsai, M.S.1    Shamon-Taylor, L.A.2    Mehmi, I.3    Tang, C.K.4    Lupu, R.5
  • 76
    • 0033190579 scopus 로고    scopus 로고
    • The mitogen activated protein kinase pathway is required for proliferation but not invasion of human squamous cell carcinoma lines
    • Tsang, D. K., and D. L. Crowe. 1999. The mitogen activated protein kinase pathway is required for proliferation but not invasion of human squamous cell carcinoma lines. Int. J. Oncol. 15:519-523.
    • (1999) Int. J. Oncol. , vol.15 , pp. 519-523
    • Tsang, D.K.1    Crowe, D.L.2
  • 77
    • 0021273420 scopus 로고
    • Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
    • Ullrich, A., L. Coussens, J. S. Hayflick, T. J. Dull, A. Gray, A. W. Tam, J. Lee, Y. Yarden, T. A. Libermann, J. Schlessinger, et al. 1984. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309:418-425.
    • (1984) Nature , vol.309 , pp. 418-425
    • Ullrich, A.1    Coussens, L.2    Hayflick, J.S.3    Dull, T.J.4    Gray, A.5    Tam, A.W.6    Lee, J.7    Yarden, Y.8    Libermann, T.A.9    Schlessinger, J.10
  • 78
    • 18544370238 scopus 로고    scopus 로고
    • Anti-HER-3 MAbs inhibit HER-3-mediated signaling in breast cancer cell lines resistant to anti-HER-2 antibodies
    • van der Horst, E. H., M. Murgia, M. Treder, and A. Ullrich. 2005. Anti-HER-3 MAbs inhibit HER-3-mediated signaling in breast cancer cell lines resistant to anti-HER-2 antibodies. Int. J. Cancer 115:519-527.
    • (2005) Int. J. Cancer , vol.115 , pp. 519-527
    • Van Der Horst, E.H.1    Murgia, M.2    Treder, M.3    Ullrich, A.4
  • 79
    • 0037376578 scopus 로고    scopus 로고
    • Roles of mitogen-activated protein kinase and phosphoinositide 3′-kinase in ErbB2/ErbB3 coreceptor-mediated heregulin signaling
    • Vijapurkar, U., M. S. Kim, and J. G. Koland. 2003. Roles of mitogen-activated protein kinase and phosphoinositide 3′-kinase in ErbB2/ErbB3 coreceptor-mediated heregulin signaling. Exp. Cell Res. 284:291-302.
    • (2003) Exp. Cell Res. , vol.284 , pp. 291-302
    • Vijapurkar, U.1    Kim, M.S.2    Koland, J.G.3
  • 80
    • 0031782321 scopus 로고    scopus 로고
    • Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation
    • Walker, F., A. Kato, L. J. Gonez, M. L. Hibbs, N. Pouliot, A. Levitzki, and A. W. Burgess. 1998. Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation. Mol. Cell. Biol. 18:7192-7204.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7192-7204
    • Walker, F.1    Kato, A.2    Gonez, L.J.3    Hibbs, M.L.4    Pouliot, N.5    Levitzki, A.6    Burgess, A.W.7
  • 81
    • 0037429692 scopus 로고    scopus 로고
    • Trafficking of the ErbB receptors and its influence on signaling
    • Wiley, H. S. 2003. Trafficking of the ErbB receptors and its influence on signaling. Exp. Cell Res. 284:78-88.
    • (2003) Exp. Cell Res. , vol.284 , pp. 78-88
    • Wiley, H.S.1
  • 82
    • 1242273590 scopus 로고    scopus 로고
    • Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016
    • Xia, W., L. H. Liu, P. Ho, and N. L. Spector. 2004. Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016. Oncogene 23:646-653.
    • (2004) Oncogene , vol.23 , pp. 646-653
    • Xia, W.1    Liu, L.H.2    Ho, P.3    Spector, N.L.4
  • 83
    • 1042289783 scopus 로고    scopus 로고
    • Inhibition of breast and ovarian tumor growth through multiple signaling pathways by using retrovirus-mediated small interfering RNA against Her-2/neu gene expression
    • Yang, G., K. Q. Cai, J. A. Thompson-Lanza, R. C. Bast, Jr., and J. Liu. 2004. Inhibition of breast and ovarian tumor growth through multiple signaling pathways by using retrovirus-mediated small interfering RNA against Her-2/neu gene expression. J. Biol. Chem. 279:4339-4345.
    • (2004) J. Biol. Chem. , vol.279 , pp. 4339-4345
    • Yang, G.1    Cai, K.Q.2    Thompson-Lanza, J.A.3    Bast Jr., R.C.4    Liu, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.