Development of zinc finger domains for recognition of the 5′-CNN-3′ family DNA sequences and their use in the construction of artificial transcription factors

Journal of Biological Chemistry

Volumn 280, Issue 42, 2005, Pages 35588-35597

  Dreier, Birgit ^a,d   Fuller, Roberta P ^a   Segal, David J ^b   Lund, Caren V ^a   Blancafort, Pilar ^a   Huber, Adrian ^a   Koksch, Beate ^c   Barbas III, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL ORGANS; DNA SEQUENCES; GENES; MUTAGENESIS;

ARTIFICIAL TRANSCRIPTION FACTORS; GENE REGULATION; NUCLEASE CLEAVAGE; REGULATORY DOMAINS;

DNA;

ADENINE; CYTOSINE; DNA; DNA BASE; GUANINE; TRANSCRIPTION FACTOR;

ARTICLE; BASE PAIRING; DNA SEQUENCE; DOWN REGULATION; ERBB2 GENE; GENE; GENE CONTROL; MOLECULAR RECOGNITION; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SITE DIRECTED MUTAGENESIS; UPREGULATION; ZINC FINGER MOTIF;

AMINO ACID SEQUENCE; ANIMALS; DEOXYRIBONUCLEASE I; DNA; DOWN-REGULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE LIBRARY; GENE TARGETING; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGONUCLEOTIDES; PEPTIDE LIBRARY; PROMOTER REGIONS (GENETICS); PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, ERBB-2; RETROVIRIDAE; SOFTWARE; TRANSCRIPTION FACTORS; UP-REGULATION; ZINC FINGERS;

EID: 27444444925     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M506654200     Document Type: Article

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