Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 27, 2012, Pages

  Lian, Xiaojun ^a,b   Hsiao, Cheston ^a   Wilson, Gisela ^c   Zhu, Kexian ^a   Hazeltine, Laurie B ^a,b   Azarin, Samira M ^a,b   Raval, Kunil K ^b,c   Zhang, Jianhua ^b,c   Kamp, Timothy J ^b,c   Palecek, Sean P ^a,b  

^a University of Wisconsin Madison   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c WiCell Research Institute   (United States)

Author keywords

Chemically defined medium; Directed differentiation

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GROWTH FACTOR; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRUCTURE; CHEMICAL ANALYSIS; ENZYME INHIBITION; GENETIC ANALYSIS; HEART MUSCLE CELL; HUMAN; HUMAN CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BETA CATENIN; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CULTURE MEDIA; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA; WNT SIGNALING PATHWAY;

EID: 84863560929     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1200250109     Document Type: Article

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