ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

Trends in Biotechnology

Volumn 31, Issue 7, 2013, Pages 397-405

  Gaj, Thomas ^a   Gersbach, Charles A ^b,c   Barbas, Carlos F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Duke University   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

Clustered regulatory interspaced short palindromic repeat; Genome engineering; Transcription activator like effector nuclease; Zinc finger nuclease

Indexed keywords

BIOLOGICAL RESEARCH; DNA DOUBLE-STRAND BREAKS; GENETIC MODIFICATIONS; GENOME ENGINEERING; NONHOMOLOGOUS END JOINING; PALINDROMIC; THERAPEUTIC POTENTIALS; ZINC-FINGER NUCLEASE;

GENES; REPAIR; RNA; TRANSCRIPTION; ZINC;

DNA;

CLUSTERED REGULATORY INTERSPACED SHORT PALINDROMIC REPEAT; DEOXYRIBONUCLEASE; NUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

DNA BINDING; DNA END JOINING REPAIR; DNA MODIFICATION; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; GENE FUNCTION; GENETIC ANALYSIS; GENETIC ENGINEERING; HUMAN; PERSONALIZED MEDICINE; PRIORITY JOURNAL; REVIEW;

BIOLOGICAL THERAPY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; DEOXYRIBONUCLEASES; GENETIC ENGINEERING; MOLECULAR BIOLOGY; RECOMBINANT PROTEINS; ZINC FINGERS;

EID: 84879264708     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2013.04.004     Document Type: Review

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