Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch

Chemistry and Biology

Volumn 5, Issue 3, 1998, Pages 119-133

  Bremer, Ryan E ^a   Baird, Eldon E ^a   Dervan, Peter B ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

DNA; Hydrogen bond; Minor groove; Molecular recognition; Transcription factor

Indexed keywords

1 METHYLIMIDAZOLE; AFFINITY LABELING; ENZYME SPECIFICITY; GENE TARGETING; GROOVE BINDING PROTEIN; N METHYLPYRROLE; NUCLEOTIDE SEQUENCE; POLYAMIDE; POSITIVE PATCH; PROTEIN DNA BINDING; TRANSCRIPTION FACTOR;

EID: 0032033739     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(98)90057-6     Document Type: Article

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