-
1
-
-
0040215628
-
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
-
Miller J., McLachlan A.D., and Klug A. Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J. 4 (1985) 1609-1614
-
(1985)
EMBO J.
, vol.4
, pp. 1609-1614
-
-
Miller, J.1
McLachlan, A.D.2
Klug, A.3
-
2
-
-
0029032723
-
Protein motif 5: zinc fingers
-
Klug A., and Schwabe J.W.R. Protein motif 5: zinc fingers. FASEB J. 9 (1995) 597-604
-
(1995)
FASEB J.
, vol.9
, pp. 597-604
-
-
Klug, A.1
Schwabe, J.W.R.2
-
3
-
-
0025773296
-
Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 Ǻ
-
Pavletich N.P., and Pabo C.O. Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 Ǻ. Science 252 (1991) 809-817
-
(1991)
Science
, vol.252
, pp. 809-817
-
-
Pavletich, N.P.1
Pabo, C.O.2
-
4
-
-
0030587774
-
Zif268 protein-DNA complex refined at 1.6 Ǻ: a model system for understanding zinc finger-DNA interactions
-
Elrod-Erickson M., Roud M.A., Nekludova L., and Pabo C.O. Zif268 protein-DNA complex refined at 1.6 Ǻ: a model system for understanding zinc finger-DNA interactions. Structure 4 (1996) 1171-1180
-
(1996)
Structure
, vol.4
, pp. 1171-1180
-
-
Elrod-Erickson, M.1
Roud, M.A.2
Nekludova, L.3
Pabo, C.O.4
-
5
-
-
0029662017
-
A 2.2 Ǻ resolution crystal structure of a designed zinc finger protein bound to DNA
-
Kim C.A., and Berg J.M. A 2.2 Ǻ resolution crystal structure of a designed zinc finger protein bound to DNA. Nat. Struct. Biol. 3 (1996) 940-945
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 940-945
-
-
Kim, C.A.1
Berg, J.M.2
-
6
-
-
0000933784
-
A consensus zinc finger peptide: design, high-affinity metal binding, a pH-dependent structure, and a His to Cys sequence variant
-
Krizek B.A., Amann B.T., Kilfoil V.J., Merkle D.L., and Berg J.M. A consensus zinc finger peptide: design, high-affinity metal binding, a pH-dependent structure, and a His to Cys sequence variant. J. Am. Chem. Soc. 113 (1991) 4518-4523
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 4518-4523
-
-
Krizek, B.A.1
Amann, B.T.2
Kilfoil, V.J.3
Merkle, D.L.4
Berg, J.M.5
-
7
-
-
0027401045
-
Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA-binding proteins
-
Desjarlais J.R., and Berg J.M. Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA-binding proteins. Proc. Natl. Acad. Sci. USA 90 (1993) 2256-2260
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2256-2260
-
-
Desjarlais, J.R.1
Berg, J.M.2
-
8
-
-
0028081691
-
Length-encoded multiplex binding site determination: application to zinc finger proteins
-
Desjarlais J.R., and Berg J.M. Length-encoded multiplex binding site determination: application to zinc finger proteins. Proc. Natl. Acad. Sci. USA 91 (1994) 11099-11103
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11099-11103
-
-
Desjarlais, J.R.1
Berg, J.M.2
-
9
-
-
0029240283
-
A direct comparison of the properties of natural and designed zinc-finger proteins
-
Shi Y., and Berg J.M. A direct comparison of the properties of natural and designed zinc-finger proteins. Chem. Biol. 2 (1995) 83-89
-
(1995)
Chem. Biol.
, vol.2
, pp. 83-89
-
-
Shi, Y.1
Berg, J.M.2
-
10
-
-
0029143651
-
2 zinc finger peptide is not, in general, responsible for base recognition
-
2 zinc finger peptide is not, in general, responsible for base recognition. J. Mol. Biol. 252 (1995) 1-5
-
(1995)
J. Mol. Biol.
, vol.252
, pp. 1-5
-
-
Kim, C.A.1
Berg, J.M.2
-
11
-
-
0032981699
-
Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences
-
Segal D.J., Dreier B., Beerli R.R., and Barbas III C.F. Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences. Proc. Natl. Acad. Sci. USA 96 (1999) 2758-2763
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2758-2763
-
-
Segal, D.J.1
Dreier, B.2
Beerli, R.R.3
Barbas III, C.F.4
-
12
-
-
47349097567
-
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification
-
Maeder M.L., Thibodeau-Beganny S., Osiak A., Wright D.A., Anthony R.M., Eichtinger M., Jiang T., Foley J.E., Winfrey R.J., Townsend J.A., Unger-Wallace E., Snader J.D., Müller-Lerch F., Fu F., Pearlberg J., Göbel C., Dassie J.P., Pruett-Miller S.M., Porteus M.H., Sgroi D.C., Iafrate A.J., Dobbs D., McCray Jr. P.B., Cathomen T., Voytas D.F., and Joung J.K. Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol. Cell 31 (2008) 294-301
-
(2008)
Mol. Cell
, vol.31
, pp. 294-301
-
-
Maeder, M.L.1
Thibodeau-Beganny, S.2
Osiak, A.3
Wright, D.A.4
Anthony, R.M.5
Eichtinger, M.6
Jiang, T.7
Foley, J.E.8
Winfrey, R.J.9
Townsend, J.A.10
Unger-Wallace, E.11
Snader, J.D.12
Müller-Lerch, F.13
Fu, F.14
Pearlberg, J.15
Göbel, C.16
Dassie, J.P.17
Pruett-Miller, S.M.18
Porteus, M.H.19
Sgroi, D.C.20
Iafrate, A.J.21
Dobbs, D.22
McCray Jr., P.B.23
Cathomen, T.24
Voytas, D.F.25
Joung, J.K.26
more..
-
13
-
-
0030940295
-
Synergy between adjacent zinc fingers in sequence-specific DNA recognition
-
Isalan M., Choo Y., and Klug A. Synergy between adjacent zinc fingers in sequence-specific DNA recognition. Proc. Natl. Acad. Sci. USA 94 (1997) 5617-5621
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5617-5621
-
-
Isalan, M.1
Choo, Y.2
Klug, A.3
-
14
-
-
0032518159
-
End effects in DNA recognition by zinc finger arrays
-
Choo Y. End effects in DNA recognition by zinc finger arrays. Nucleic Acids Res. 26 (1998) 554-557
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 554-557
-
-
Choo, Y.1
-
15
-
-
0032168890
-
Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers
-
Isalan M., Klug A., and Choo Y. Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers. Biochemistry 37 (1998) 12026-12033
-
(1998)
Biochemistry
, vol.37
, pp. 12026-12033
-
-
Isalan, M.1
Klug, A.2
Choo, Y.3
-
16
-
-
0037018930
-
Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table
-
Sera T., and Uranga C. Rational design of artificial zinc-finger proteins using a nondegenerate recognition code table. Biochemistry 41 (2002) 7074-7081
-
(2002)
Biochemistry
, vol.41
, pp. 7074-7081
-
-
Sera, T.1
Uranga, C.2
-
17
-
-
0026742626
-
Toward rules relating zinc finger protein sequences and DNA-binding site preferences
-
Desjarlais J.R., and Berg J.M. Toward rules relating zinc finger protein sequences and DNA-binding site preferences. Proc. Natl. Acad. Sci. USA 89 (1992) 7345-7349
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7345-7349
-
-
Desjarlais, J.R.1
Berg, J.M.2
-
18
-
-
0026718890
-
Mutations in the zinc fingers of ADR1 that change the specificity of DNA binding and transctivation
-
Thukral S.K., Morrison M.L., and Young E.T. Mutations in the zinc fingers of ADR1 that change the specificity of DNA binding and transctivation. Mol. Cell. Biol. 12 (1992) 2784-2792
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2784-2792
-
-
Thukral, S.K.1
Morrison, M.L.2
Young, E.T.3
-
19
-
-
0028328872
-
Zinc finger phage: affinity selection of fingers with new DNA-binding specificities
-
Rebar E.J., and Pabo C.O. Zinc finger phage: affinity selection of fingers with new DNA-binding specificities. Science 263 (1993) 671-673
-
(1993)
Science
, vol.263
, pp. 671-673
-
-
Rebar, E.J.1
Pabo, C.O.2
-
20
-
-
0028227930
-
In vitro selection of zinc fingers with altered DNA-binding specificity
-
Jamieson A.C., Kim S.-H., and Wells J.A. In vitro selection of zinc fingers with altered DNA-binding specificity. Biochemistry 33 (1994) 5689-5695
-
(1994)
Biochemistry
, vol.33
, pp. 5689-5695
-
-
Jamieson, A.C.1
Kim, S.-H.2
Wells, J.A.3
-
21
-
-
65749112148
-
Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage
-
Choo Y., and Klug A. Toward a code for the interactions of zinc fingers with DNA: selection of randomized fingers displayed on phage. Proc. Natl. Acad. Sci. USA 92 (1995) 344-348
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 344-348
-
-
Choo, Y.1
Klug, A.2
-
22
-
-
65749087791
-
Building zinc fingers by selection: toward a therapeutic application
-
Wu H., Yang W.-P., and Barbas III C.F. Building zinc fingers by selection: toward a therapeutic application. Proc. Natl. Acad. Sci. USA 91 (1994) 11163-11167
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11163-11167
-
-
Wu, H.1
Yang, W.-P.2
Barbas III, C.F.3
-
23
-
-
0033930952
-
Advances in zinc finger engineering
-
Choo Y., and Isalan M. Advances in zinc finger engineering. Curr. Opin. Struct. Biol. 10 (2000) 41-416
-
(2000)
Curr. Opin. Struct. Biol.
, vol.10
, pp. 41-416
-
-
Choo, Y.1
Isalan, M.2
-
24
-
-
0036168937
-
Engineering polydactyl zinc-finger transcription factors
-
Beerli R.R., and Barbas III C.F. Engineering polydactyl zinc-finger transcription factors. Nat. Biotrechnol. 20 (2002) 135-141
-
(2002)
Nat. Biotrechnol.
, vol.20
, pp. 135-141
-
-
Beerli, R.R.1
Barbas III, C.F.2
-
26
-
-
0344874246
-
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities
-
Uil T.G., Haisma H.J., and Rots M.G. Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities. Nucleic Acids Res. 31 (2003) 6064-6078
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6064-6078
-
-
Uil, T.G.1
Haisma, H.J.2
Rots, M.G.3
-
28
-
-
23444441147
-
Gene targeting using zinc finger nucleases
-
Porteus M.H., and Carroll D. Gene targeting using zinc finger nucleases. Nat. Biotechnol. 23 (2005) 967-973
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 967-973
-
-
Porteus, M.H.1
Carroll, D.2
-
29
-
-
53849085827
-
New redesigned zinc-finger proteins: design strategy and its application
-
Negi S., Imanishi M., Matsumoto M., and Sugiura Y. New redesigned zinc-finger proteins: design strategy and its application. Chem. Eur. J. 14 (2008) 3236-3249
-
(2008)
Chem. Eur. J.
, vol.14
, pp. 3236-3249
-
-
Negi, S.1
Imanishi, M.2
Matsumoto, M.3
Sugiura, Y.4
-
30
-
-
0035815697
-
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions
-
Liu P.-P., Rebar E.J., Zhang L., Liu Q., Jamieson A.C., Liang Y., Qi H., Li P.-X., Chen B., Mendel M.C., Zhong X., Lee Y.-L., Eisenberg S.P., Spratt S.K., Case C.C., and Wolffe A.P. Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. J. Biol. Chem. 276 (2001) 11323-11334
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11323-11334
-
-
Liu, P.-P.1
Rebar, E.J.2
Zhang, L.3
Liu, Q.4
Jamieson, A.C.5
Liang, Y.6
Qi, H.7
Li, P.-X.8
Chen, B.9
Mendel, M.C.10
Zhong, X.11
Lee, Y.-L.12
Eisenberg, S.P.13
Spratt, S.K.14
Case, C.C.15
Wolffe, A.P.16
-
31
-
-
0034721877
-
Synthetic zinc finger transcription factor action at an endogenous chromosomal site
-
Zhang L., Spratt S.K., Liu Q., Johnstone B., Qi H., Raschke E.E., Jamieson A.C., Rebar E.J., Wolffe A.P., and Case C.C. Synthetic zinc finger transcription factor action at an endogenous chromosomal site. J. Biol. Chem. 275 (2000) 33850-33860
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33850-33860
-
-
Zhang, L.1
Spratt, S.K.2
Liu, Q.3
Johnstone, B.4
Qi, H.5
Raschke, E.E.6
Jamieson, A.C.7
Rebar, E.J.8
Wolffe, A.P.9
Case, C.C.10
-
32
-
-
0344284577
-
Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors
-
Jouvenot Y., Ginjala V., Zhang L., Liu P.-Q., Oshimura M., Feinberg A.P., Wolffe A.P., Ohlsson R., and Gregory P.D. Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors. Gene Ther. 10 (2003) 513-522
-
(2003)
Gene Ther.
, vol.10
, pp. 513-522
-
-
Jouvenot, Y.1
Ginjala, V.2
Zhang, L.3
Liu, P.-Q.4
Oshimura, M.5
Feinberg, A.P.6
Wolffe, A.P.7
Ohlsson, R.8
Gregory, P.D.9
-
33
-
-
35548972517
-
Gene transfer of an engineered zinc finger protein enhances the anti-angiogenic defense system
-
Yokoi K., Zhang H.S., Kachi S., Balaggan K.S., Yu Q., Guschin D., Kunis M., Surosky R., Africa L.M., Bainbridge J.W., Spratt S.K., Gregory P.D., Ali R.R., and Campochiaro P.A. Gene transfer of an engineered zinc finger protein enhances the anti-angiogenic defense system. Mol. Ther. 15 (2007) 1917-1923
-
(2007)
Mol. Ther.
, vol.15
, pp. 1917-1923
-
-
Yokoi, K.1
Zhang, H.S.2
Kachi, S.3
Balaggan, K.S.4
Yu, Q.5
Guschin, D.6
Kunis, M.7
Surosky, R.8
Africa, L.M.9
Bainbridge, J.W.10
Spratt, S.K.11
Gregory, P.D.12
Ali, R.R.13
Campochiaro, P.A.14
-
34
-
-
0035800769
-
Development of zinc finger domains for recognition of the 5′-ANN-3′ family of DNA sequences and their use in the construction of artificial transcription factors
-
Dreier B., Beerli R.R., Segal D.J., Flippin J.D., and Barbas III C.F. Development of zinc finger domains for recognition of the 5′-ANN-3′ family of DNA sequences and their use in the construction of artificial transcription factors. J. Biol. Chem. 276 (2001) 29466-29478
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29466-29478
-
-
Dreier, B.1
Beerli, R.R.2
Segal, D.J.3
Flippin, J.D.4
Barbas III, C.F.5
-
35
-
-
27444444925
-
Development of zinc finger domains for recognition of the 5′-CNN-3′ family DNA sequences and their use in the construction of artificial transcription factors
-
Dreier B., Fuller R.P., Segal D.J., Lund C.V., Blancafort P., Huber A., Koksch B., and Barbas III C.F. Development of zinc finger domains for recognition of the 5′-CNN-3′ family DNA sequences and their use in the construction of artificial transcription factors. J. Biol. Chem. 280 (2005) 35588-35597
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35588-35597
-
-
Dreier, B.1
Fuller, R.P.2
Segal, D.J.3
Lund, C.V.4
Blancafort, P.5
Huber, A.6
Koksch, B.7
Barbas III, C.F.8
-
36
-
-
0037335514
-
Human zinc fingers as building blocks in the construction of artificial transcription factors
-
Bae K.-H., Kwon Y.D., Shin H.-C., Hwang M.-S., Ryu E.-H., Park K.-S., Yang H.-Y., Lee D., Lee Y., Park J., Kwon H.S., Kim H.-W., Yeh B.-I., Lee H.-W., Sohn S.H., Yoon J., Soel W., and Kim J.-S. Human zinc fingers as building blocks in the construction of artificial transcription factors. Nat. Biotechnol. 21 (2003) 275-280
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 275-280
-
-
Bae, K.-H.1
Kwon, Y.D.2
Shin, H.-C.3
Hwang, M.-S.4
Ryu, E.-H.5
Park, K.-S.6
Yang, H.-Y.7
Lee, D.8
Lee, Y.9
Park, J.10
Kwon, H.S.11
Kim, H.-W.12
Yeh, B.-I.13
Lee, H.-W.14
Sohn, S.H.15
Yoon, J.16
Soel, W.17
Kim, J.-S.18
-
37
-
-
33747816812
-
Zinc finger tools: custom DNA-binding domains for transcription factors and nucleases
-
Mandell J.G., and Barbas III C.F. Zinc finger tools: custom DNA-binding domains for transcription factors and nucleases. Nucleic Acids Res. 34 (2006) W516-W523
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Mandell, J.G.1
Barbas III, C.F.2
-
38
-
-
0028046895
-
Selection of DNA-binding sites for zinc fingers using rationally randomized DNA reveals coded interactions
-
Choo Y., and Klug A. Selection of DNA-binding sites for zinc fingers using rationally randomized DNA reveals coded interactions. Proc. Natl. Acad. Sci. USA 91 (1994) 11168-11172
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11168-11172
-
-
Choo, Y.1
Klug, A.2
-
39
-
-
0033524954
-
Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code
-
Wolfe S.A., Greisman H.A., Ramm E.I., and Pabo C.O. Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code. J. Mol. Biol. 285 (1999) 1917-1934
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 1917-1934
-
-
Wolfe, S.A.1
Greisman, H.A.2
Ramm, E.I.3
Pabo, C.O.4
-
40
-
-
6344227879
-
Regulation of the endogenous VEGF-A gene by exogenous designed regulatory proteins
-
Tachikawa K., Schroder O., Frey G., Briggs S.P., and Sera T. Regulation of the endogenous VEGF-A gene by exogenous designed regulatory proteins. Proc. Natl. Acad. Sci. USA 101 (2004) 15225-15230
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15225-15230
-
-
Tachikawa, K.1
Schroder, O.2
Frey, G.3
Briggs, S.P.4
Sera, T.5
-
41
-
-
13444301361
-
Inhibition of virus DNA replication by artificial zinc finger proteins
-
Sera T. Inhibition of virus DNA replication by artificial zinc finger proteins. J. Virol. 79 (2005) 2614-2619
-
(2005)
J. Virol.
, vol.79
, pp. 2614-2619
-
-
Sera, T.1
-
42
-
-
33646739107
-
Inhibition of DNA replication of human papillomavirus by artificial zinc finger proteins
-
Mino T., Hatono T., Matsumoto N., Mori T., Mineta Y., Aoyama Y., and Sera T. Inhibition of DNA replication of human papillomavirus by artificial zinc finger proteins. J. Virol. 80 (2006) 5405-5412
-
(2006)
J. Virol.
, vol.80
, pp. 5405-5412
-
-
Mino, T.1
Hatono, T.2
Matsumoto, N.3
Mori, T.4
Mineta, Y.5
Aoyama, Y.6
Sera, T.7
-
43
-
-
45849133735
-
Cell-permeable artificial zinc-finger proteins as potent antiviral drugs for human papillomaviruses
-
Mino T., Mori T., Aoyama Y., and Sera T. Cell-permeable artificial zinc-finger proteins as potent antiviral drugs for human papillomaviruses. Arch. Virol. 153 (2008) 1291-1298
-
(2008)
Arch. Virol.
, vol.153
, pp. 1291-1298
-
-
Mino, T.1
Mori, T.2
Aoyama, Y.3
Sera, T.4
-
44
-
-
51649084498
-
Protein engineering: the fate of fingers
-
Pearson H. Protein engineering: the fate of fingers. Nature 455 (2008) 160-164
-
(2008)
Nature
, vol.455
, pp. 160-164
-
-
Pearson, H.1
-
45
-
-
0029010951
-
Surface plasmon resonance based kinetic studies of zinc finger-DNA interactions
-
Yang W.-P., Wu H., and Barbas III C.F. Surface plasmon resonance based kinetic studies of zinc finger-DNA interactions. J. Immunol. Methods 183 (1995) 175-182
-
(1995)
J. Immunol. Methods
, vol.183
, pp. 175-182
-
-
Yang, W.-P.1
Wu, H.2
Barbas III, C.F.3
-
46
-
-
0030716480
-
Synthesis of a new finger peptide; comparison of its "code" deduced and "CASTing" derived binding sites
-
Corbi N., Perez M., Maione R., and Passananti C. Synthesis of a new finger peptide; comparison of its "code" deduced and "CASTing" derived binding sites. FEBS Lett. 417 (1997) 71-74
-
(1997)
FEBS Lett.
, vol.417
, pp. 71-74
-
-
Corbi, N.1
Perez, M.2
Maione, R.3
Passananti, C.4
-
47
-
-
0035912721
-
Exploring the DNA-binding specificities of zinc fingers with DNA microarrays
-
Bulyk M.L., Huang X., Choo Y., and Church G.M. Exploring the DNA-binding specificities of zinc fingers with DNA microarrays. Proc. Natl. Acad. Sci. USA 99 (2001) 7158-7163
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7158-7163
-
-
Bulyk, M.L.1
Huang, X.2
Choo, Y.3
Church, G.M.4
-
48
-
-
23444446753
-
A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors
-
Meng X., Brodsky M.H., and Wolfe S.A. A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors. Nat. Biotechnol. 23 (2005) 988-994
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 988-994
-
-
Meng, X.1
Brodsky, M.H.2
Wolfe, S.A.3
-
49
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
Kalderon D., Roberts B.L., Richardson W.D., and Smith A.E. A short amino acid sequence able to specify nuclear location. Cell 39 (1984) 499-509
-
(1984)
Cell
, vol.39
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
50
-
-
0024024137
-
Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression
-
Triezenberg S.J., Kingsbury R.C., and McKnight S.L. Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes Dev. 2 (1988) 718-729
-
(1988)
Genes Dev.
, vol.2
, pp. 718-729
-
-
Triezenberg, S.J.1
Kingsbury, R.C.2
McKnight, S.L.3
-
51
-
-
0028183182
-
Krüppel-associated boxes are potent transcriptional repression domains
-
Margolin J.F., Friedman J.R., Meyer W.K.-H., Vissing H., Thiesen H.-J., and Rauscher III F.J. Krüppel-associated boxes are potent transcriptional repression domains. Proc. Natl. Acad. Sci. USA 91 (1994) 4509-4513
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4509-4513
-
-
Margolin, J.F.1
Friedman, J.R.2
Meyer, W.K.-H.3
Vissing, H.4
Thiesen, H.-J.5
Rauscher III, F.J.6
-
53
-
-
0034988731
-
A versatile framework for the design of ligand-dependent, transgene-specific transcription factors
-
Xu L., Zerby D., Huang Y., Ji H., Nyanguile O.F., de los Angeles J.E., and Kadan M.J. A versatile framework for the design of ligand-dependent, transgene-specific transcription factors. Mol. Ther. 3 (2001) 262-273
-
(2001)
Mol. Ther.
, vol.3
, pp. 262-273
-
-
Xu, L.1
Zerby, D.2
Huang, Y.3
Ji, H.4
Nyanguile, O.F.5
de los Angeles, J.E.6
Kadan, M.J.7
-
54
-
-
9144250992
-
Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors
-
Snowden A.W., Zhang L., Urnov F., Dent C., Jouvenot Y., Zhong X., Rebar E.J., Jamieson A.C., Zhang H.S., Tan S., Case C.C., Pabo C.O., Wolffe A.P., and Gregory P.D. Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors. Cancer Res. 63 (2003) 8968-8976
-
(2003)
Cancer Res.
, vol.63
, pp. 8968-8976
-
-
Snowden, A.W.1
Zhang, L.2
Urnov, F.3
Dent, C.4
Jouvenot, Y.5
Zhong, X.6
Rebar, E.J.7
Jamieson, A.C.8
Zhang, H.S.9
Tan, S.10
Case, C.C.11
Pabo, C.O.12
Wolffe, A.P.13
Gregory, P.D.14
-
55
-
-
34548509209
-
Regulation of endogenous gene expression using small molecule-controlled engineered zinc-finger protein transcription factors
-
Dent C.L., Lau G., Drake E.A., Yoon A., Case C.C., and Gregory P.D. Regulation of endogenous gene expression using small molecule-controlled engineered zinc-finger protein transcription factors. Gene Ther. 15 (2007) 1362-1369
-
(2007)
Gene Ther.
, vol.15
, pp. 1362-1369
-
-
Dent, C.L.1
Lau, G.2
Drake, E.A.3
Yoon, A.4
Case, C.C.5
Gregory, P.D.6
-
56
-
-
50049095016
-
Drug-inducible and simultaneous regulation of endogenous genes by single-chain nuclear receptor-based zinc-finger transcription factor gene switches
-
Magnenat L., Schwimmer L.J., and Barbas III C.F. Drug-inducible and simultaneous regulation of endogenous genes by single-chain nuclear receptor-based zinc-finger transcription factor gene switches. Gene Ther. 15 (2008) 1223-1232
-
(2008)
Gene Ther.
, vol.15
, pp. 1223-1232
-
-
Magnenat, L.1
Schwimmer, L.J.2
Barbas III, C.F.3
-
57
-
-
0034700090
-
Delivery of a stringent dimerizer-regulated gene expression system in a single retroviral vector
-
Pollock R., Issner R., Zoller K., Natesan S., Rivera V.M., and Clackson T. Delivery of a stringent dimerizer-regulated gene expression system in a single retroviral vector. Proc. Natl. Acad. Sci. USA 97 (2000) 13221-13226
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13221-13226
-
-
Pollock, R.1
Issner, R.2
Zoller, K.3
Natesan, S.4
Rivera, V.M.5
Clackson, T.6
-
58
-
-
0035989652
-
Regulation of endogenous gene expression with a small molecule dimerizer
-
Pollock R., Giel M., Linher K., and Clackson T. Regulation of endogenous gene expression with a small molecule dimerizer. Nat. Biotechnol. 20 (2002) 729-733
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 729-733
-
-
Pollock, R.1
Giel, M.2
Linher, K.3
Clackson, T.4
-
59
-
-
13844254266
-
Cell-penetrating peptides: mechanisms and kinetics of cargo delivery
-
Zorko M., and Langel U. Cell-penetrating peptides: mechanisms and kinetics of cargo delivery. Adv. Drug Deliv. Rev. 57 (2005) 529-545
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 529-545
-
-
Zorko, M.1
Langel, U.2
-
60
-
-
33646844421
-
In vitro selection of zinc finger DNA-binding proteins through ribosome display
-
Ihara H., Mie M., Funabashi H., Takahashi F., Sawasaki T., Endo Y., and Kobatake E. In vitro selection of zinc finger DNA-binding proteins through ribosome display. Biochem. Biophys. Res. Commun. 345 (2006) 1149-1154
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.345
, pp. 1149-1154
-
-
Ihara, H.1
Mie, M.2
Funabashi, H.3
Takahashi, F.4
Sawasaki, T.5
Endo, Y.6
Kobatake, E.7
-
61
-
-
33745812434
-
One-step selection of artificial transcription factors using an in vivo screening system
-
Bae K.-H., and Kim J.-S. One-step selection of artificial transcription factors using an in vivo screening system. Mol. Cells 21 (2006) 376-380
-
(2006)
Mol. Cells
, vol.21
, pp. 376-380
-
-
Bae, K.-H.1
Kim, J.-S.2
-
62
-
-
0034691202
-
A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions
-
Joung J.K., Ramm E.I., and Pabo C.O. A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions. Proc. Natl. Acad. Sci. USA 97 (2000) 7382-7387
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7382-7387
-
-
Joung, J.K.1
Ramm, E.I.2
Pabo, C.O.3
-
63
-
-
0142091373
-
Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection
-
Hurt J.A., Thibodeau S.A., Hirsh A.S., Pabo C.O., and Joung J.K. Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection. Proc. Natl. Acad. Sci. USA 100 (2003) 12271-12276
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12271-12276
-
-
Hurt, J.A.1
Thibodeau, S.A.2
Hirsh, A.S.3
Pabo, C.O.4
Joung, J.K.5
-
64
-
-
33744480822
-
A bacterial one-hybrid selection system for interrogating zinc finger-DNA interactions
-
Durai S., Bosley A., Abulencia A.B., Chandrasegaran S., and Ostermeier M. A bacterial one-hybrid selection system for interrogating zinc finger-DNA interactions. Comb. Chem. High Throughput Screen. 9 (2006) 301-311
-
(2006)
Comb. Chem. High Throughput Screen.
, vol.9
, pp. 301-311
-
-
Durai, S.1
Bosley, A.2
Abulencia, A.B.3
Chandrasegaran, S.4
Ostermeier, M.5
-
65
-
-
27644566231
-
Cell-free selection of zinc finger DNA-binding proteins using in vitro compartmentalization
-
Sepp A., and Choo Y. Cell-free selection of zinc finger DNA-binding proteins using in vitro compartmentalization. J. Mol. Biol. 354 (2005) 212-219
-
(2005)
J. Mol. Biol.
, vol.354
, pp. 212-219
-
-
Sepp, A.1
Choo, Y.2
-
66
-
-
0028670569
-
In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
-
Choo Y., Sanchez-Garcia I., and Klug A. In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence. Nature 372 (1994) 642-645
-
(1994)
Nature
, vol.372
, pp. 642-645
-
-
Choo, Y.1
Sanchez-Garcia, I.2
Klug, A.3
-
67
-
-
0030903688
-
Design of polydactyl zinc-finger proteins for unique addressing within complex genomes
-
Liu Q., Segal D.J., Ghiara J.B., and Barbas III C.F. Design of polydactyl zinc-finger proteins for unique addressing within complex genomes. Proc. Natl. Acad. Sci. USA 94 (1997) 5525-5530
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5525-5530
-
-
Liu, Q.1
Segal, D.J.2
Ghiara, J.B.3
Barbas III, C.F.4
-
68
-
-
0032437591
-
Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
-
Beerli R.R., Segal D.J., Dreier B., and Barbas III CF. Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks. Proc. Natl. Acad. Sci. USA 95 (1998) 14628-14633
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14628-14633
-
-
Beerli, R.R.1
Segal, D.J.2
Dreier, B.3
Barbas III, CF.4
-
69
-
-
0034652141
-
Positive and negative regulation of endogenous genes by designed transcription factors
-
Beerli R.R., Dreier B., and Barbas III C.F. Positive and negative regulation of endogenous genes by designed transcription factors. Proc. Natl. Acad. Sci. USA 97 (2000) 1495-1500
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1495-1500
-
-
Beerli, R.R.1
Dreier, B.2
Barbas III, C.F.3
-
70
-
-
0033917833
-
Regulation of the MDR1gene by transcriptional repressors selected using peptide combinatorial libraries
-
Bartsevich V.V., and Juliano R.L. Regulation of the MDR1gene by transcriptional repressors selected using peptide combinatorial libraries. Mol. Pharmacol. 58 (2000) 1-10
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 1-10
-
-
Bartsevich, V.V.1
Juliano, R.L.2
-
71
-
-
26444464763
-
Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: insights into ErbB receptor biology
-
Lund G.V., Popkov M., Magnenat L., and Barbas III C.F. Zinc finger transcription factors designed for bispecific coregulation of ErbB2 and ErbB3 receptors: insights into ErbB receptor biology. Mol. Cell. Biol. 25 (2005) 9082-9091
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9082-9091
-
-
Lund, G.V.1
Popkov, M.2
Magnenat, L.3
Barbas III, C.F.4
-
72
-
-
0036912846
-
Induction of angiogenesis in a mouse model using engineered transcription factors
-
Rebar E.J., Huang Y., Hickey R., Nath A.K., Meoli D., Nath S., Chen B., Xu L., Liang Y., Jamieson A.C., Zhang L., Spratt S.K., Case C.C., Wolffe A., and Giordano F.J. Induction of angiogenesis in a mouse model using engineered transcription factors. Nat. Med. 8 (2002) 1427-1432
-
(2002)
Nat. Med.
, vol.8
, pp. 1427-1432
-
-
Rebar, E.J.1
Huang, Y.2
Hickey, R.3
Nath, A.K.4
Meoli, D.5
Nath, S.6
Chen, B.7
Xu, L.8
Liang, Y.9
Jamieson, A.C.10
Zhang, L.11
Spratt, S.K.12
Case, C.C.13
Wolffe, A.14
Giordano, F.J.15
-
73
-
-
33645838355
-
An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice
-
Yu J., Lei L., Liang Y., Hinh L., Hickey R.P., Huang Y., Liu D., Yeh J.L., Rebar E., Case C., Spratt K., Sessa W.C., and Giordano F.J. An engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice. FASEB J. 20 (2006) 479-481
-
(2006)
FASEB J.
, vol.20
, pp. 479-481
-
-
Yu, J.1
Lei, L.2
Liang, Y.3
Hinh, L.4
Hickey, R.P.5
Huang, Y.6
Liu, D.7
Yeh, J.L.8
Rebar, E.9
Case, C.10
Spratt, K.11
Sessa, W.C.12
Giordano, F.J.13
-
74
-
-
33748329461
-
Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy
-
Price S.A., Dent C., Duran-Jimenez B., Ling Y., Zhang L., Rebar E.J., Case C.C., Gregory P.D., Martin T.J., Spratt S.K., and Tomlinson D.R. Gene transfer of an engineered transcription factor promoting expression of VEGF-A protects against experimental diabetic neuropathy. Diabetes 55 (2006) 1847-1854
-
(2006)
Diabetes
, vol.55
, pp. 1847-1854
-
-
Price, S.A.1
Dent, C.2
Duran-Jimenez, B.3
Ling, Y.4
Zhang, L.5
Rebar, E.J.6
Case, C.C.7
Gregory, P.D.8
Martin, T.J.9
Spratt, S.K.10
Tomlinson, D.R.11
-
75
-
-
6444236227
-
Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia
-
Dai Q., Huang J., Klitzman B., Dong C., Goldschmidt-Clermont P.J., March K.L., Rokovich J., Johnstone B., Rebar E.J., Spratt S.K., Case C.C., Kontos C.D., and Annex B.H. Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia. Circulation 110 (2004) 2467-2475
-
(2004)
Circulation
, vol.110
, pp. 2467-2475
-
-
Dai, Q.1
Huang, J.2
Klitzman, B.3
Dong, C.4
Goldschmidt-Clermont, P.J.5
March, K.L.6
Rokovich, J.7
Johnstone, B.8
Rebar, E.J.9
Spratt, S.K.10
Case, C.C.11
Kontos, C.D.12
Annex, B.H.13
-
76
-
-
0038806468
-
Dominant repression of target genes by chimeric repressors that include the EAR motif, a repression domain, in Arabidopsis
-
Hirastu K., Matsui K., Koyama T., and Ohme-Takagi M. Dominant repression of target genes by chimeric repressors that include the EAR motif, a repression domain, in Arabidopsis. Plant J. 34 (2003) 733-739
-
(2003)
Plant J.
, vol.34
, pp. 733-739
-
-
Hirastu, K.1
Matsui, K.2
Koyama, T.3
Ohme-Takagi, M.4
-
77
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vivès E., Brodin P., and Lebleu B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272 (1997) 16010-16017
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16010-16017
-
-
Vivès, E.1
Brodin, P.2
Lebleu, B.3
-
78
-
-
0035863391
-
Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo
-
Ho A., Schwarze S.R., Mermelstein S.J., Waksman G., and Dowdy S.F. Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo. Cancer Res. 61 (2001) 474-477
-
(2001)
Cancer Res.
, vol.61
, pp. 474-477
-
-
Ho, A.1
Schwarze, S.R.2
Mermelstein, S.J.3
Waksman, G.4
Dowdy, S.F.5
-
79
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters
-
Wender P.A., Mitchell D.J., Pattabiraman K., Pelkey E.T., Steinman L., and Rothbard J.B. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl. Acad. Sci. USA 97 (2000) 13003-13008
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
80
-
-
44349095918
-
Novel cancer antiangiotherapy using the VEGF promoter-targeted artificial zinc-finger protein and oncolytic adenovirus
-
Kang Y.-A., Shin H.-C., Yoo J.Y., Kim J.-H., Kim J.-S., and Yun C.-O. Novel cancer antiangiotherapy using the VEGF promoter-targeted artificial zinc-finger protein and oncolytic adenovirus. Mol. Ther. 16 (2008) 1033-1040
-
(2008)
Mol. Ther.
, vol.16
, pp. 1033-1040
-
-
Kang, Y.-A.1
Shin, H.-C.2
Yoo, J.Y.3
Kim, J.-H.4
Kim, J.-S.5
Yun, C.-O.6
-
81
-
-
27244436299
-
Suppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels
-
Kwon H.-S., Shin H.-C., and Kim J.-S. Suppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels. Nucleic Acids Res. 33 (2005) e74
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Kwon, H.-S.1
Shin, H.-C.2
Kim, J.-S.3
-
82
-
-
34848856424
-
E1A- and E1B-double mutant replicating adenovirus elicits enhanced oncolytic and antitumor effects
-
Kim J., Kim J.-H., Choi K.-J., Kim P.-W., and Yun C.-O. E1A- and E1B-double mutant replicating adenovirus elicits enhanced oncolytic and antitumor effects. Hum. Gene Ther. 18 (2007) 773-786
-
(2007)
Hum. Gene Ther.
, vol.18
, pp. 773-786
-
-
Kim, J.1
Kim, J.-H.2
Choi, K.-J.3
Kim, P.-W.4
Yun, C.-O.5
-
83
-
-
65749111029
-
PPARg knockdown by engineered transcription factors: exogenous PPARg2but not PPARg1 reactivates adipogenesis
-
Ren D., Collingwood T.N., Rebar E.J., Wolffe A.P., and Camp H.S. PPARg knockdown by engineered transcription factors: exogenous PPARg2but not PPARg1 reactivates adipogenesis. Genes Dev. 2 (1988) 718-729
-
(1988)
Genes Dev.
, vol.2
, pp. 718-729
-
-
Ren, D.1
Collingwood, T.N.2
Rebar, E.J.3
Wolffe, A.P.4
Camp, H.S.5
-
84
-
-
0037315952
-
Design of artificial transcription factors to selectively regulate the pro-apoptotic bax gene
-
Falke D., Fisher M., Ye D., and Juliano R.L. Design of artificial transcription factors to selectively regulate the pro-apoptotic bax gene. Nucleic Acids Res. 31 (2003) e10
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Falke, D.1
Fisher, M.2
Ye, D.3
Juliano, R.L.4
-
85
-
-
0142165907
-
Engineered zinc finger proteins for controlling stem cell fate
-
Bartsevich V.V., Miller J.C., Case C.C., and Pabo C.O. Engineered zinc finger proteins for controlling stem cell fate. Stem Cells 21 (2003) 532-637
-
(2003)
Stem Cells
, vol.21
, pp. 532-637
-
-
Bartsevich, V.V.1
Miller, J.C.2
Case, C.C.3
Pabo, C.O.4
-
86
-
-
0142027810
-
Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity
-
Tan S., Guschin D., Davalos A., Lee Y.-L., Snowden A.W., Jouvenot Y., Zhang H.S., Howes K., McNamara A.R., lai A., Ullman C., Reynolds L., Moore M., Isalan M., Berg L.-P., Campos B., Qi H., Spratt S.K., Case C.C., Pabo C.O., Campisis J., and Gregory P.D. Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity. Proc. Natl. Acad. Sci. USA 100 (2003) 11997-12002
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11997-12002
-
-
Tan, S.1
Guschin, D.2
Davalos, A.3
Lee, Y.-L.4
Snowden, A.W.5
Jouvenot, Y.6
Zhang, H.S.7
Howes, K.8
McNamara, A.R.9
lai, A.10
Ullman, C.11
Reynolds, L.12
Moore, M.13
Isalan, M.14
Berg, L.-P.15
Campos, B.16
Qi, H.17
Spratt, S.K.18
Case, C.C.19
Pabo, C.O.20
Campisis, J.21
Gregory, P.D.22
more..
-
87
-
-
4544378740
-
Cell lines for drug discovery: elevating target-protein levels using engineered transcription factors
-
Liu P.-Q., Morton M.F., Reik A., De La Rosa R., Mendel M.C., Li X.-Y., Case C.C., Pabo C.O., Moreno V., Kempf A., Pyati J., and Shankley N.P. Cell lines for drug discovery: elevating target-protein levels using engineered transcription factors. J. Biomol. Screen. 9 (2004) 44-51
-
(2004)
J. Biomol. Screen.
, vol.9
, pp. 44-51
-
-
Liu, P.-Q.1
Morton, M.F.2
Reik, A.3
De La Rosa, R.4
Mendel, M.C.5
Li, X.-Y.6
Case, C.C.7
Pabo, C.O.8
Moreno, V.9
Kempf, A.10
Pyati, J.11
Shankley, N.P.12
-
88
-
-
20444423632
-
Isogenic human cell lines for drug discovery: regulation of target gene expression by engineered zinc-finger protein transcription factors
-
Liu P.-Q., Tan S., Mendel M.C., Murrills R.J., Bhat B.M., Schlag B., Samuel R., Matteo J.J., deLa Rosa R., Howes K., Reik A., Case C.C., Bex F.J., Young K., and Gregory P.D. Isogenic human cell lines for drug discovery: regulation of target gene expression by engineered zinc-finger protein transcription factors. J. Biomol. Screen. 10 (2005) 304-313
-
(2005)
J. Biomol. Screen.
, vol.10
, pp. 304-313
-
-
Liu, P.-Q.1
Tan, S.2
Mendel, M.C.3
Murrills, R.J.4
Bhat, B.M.5
Schlag, B.6
Samuel, R.7
Matteo, J.J.8
deLa Rosa, R.9
Howes, K.10
Reik, A.11
Case, C.C.12
Bex, F.J.13
Young, K.14
Gregory, P.D.15
-
89
-
-
13544277695
-
Exploring strategies for the design of artificial transcription factors
-
Gräslund T., Li X., Magnenat L., Popkov M., and Barbas III C.F. Exploring strategies for the design of artificial transcription factors. J. Biol. Chem. 280 (2005) 3707-3714
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 3707-3714
-
-
Gräslund, T.1
Li, X.2
Magnenat, L.3
Popkov, M.4
Barbas III, C.F.5
-
90
-
-
34247492871
-
Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors
-
Beltran A., Parikh S., Liu Y., Johnson G.L., Futscher B.W., and Blancafort P. Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors. Oncogene 26 (2007) 2791-2798
-
(2007)
Oncogene
, vol.26
, pp. 2791-2798
-
-
Beltran, A.1
Parikh, S.2
Liu, Y.3
Johnson, G.L.4
Futscher, B.W.5
Blancafort, P.6
-
91
-
-
34347380196
-
The artificial 4-zinc-finger protein Bagly binds human utrophin promoter A at the endogenous chromosomal site and activates transcription
-
Onori A., Desantis A., Buontempo S., Grazia M., Di Certo, Fanciulli M., Salvatori L., Passananti C., and Corbi N. The artificial 4-zinc-finger protein Bagly binds human utrophin promoter A at the endogenous chromosomal site and activates transcription. Biochem. Cell. Biol. 85 (2007) 358-365
-
(2007)
Biochem. Cell. Biol.
, vol.85
, pp. 358-365
-
-
Onori, A.1
Desantis, A.2
Buontempo, S.3
Grazia, M.4
Di Certo5
Fanciulli, M.6
Salvatori, L.7
Passananti, C.8
Corbi, N.9
-
92
-
-
40749102811
-
Utrophin up-regulation by an artificial transcription factor in transgenic mice
-
Mattei E., Corbi N., Di Certo M.G., Strimpakos G., Severini C., Onori A., Desantis A., Libri V., Buontempo S., Floridi A., Fanciulli M., Baban D., Davies K.E., and Passananti C. Utrophin up-regulation by an artificial transcription factor in transgenic mice. PLoS One 2 (2007) e774
-
(2007)
PLoS One
, vol.2
-
-
Mattei, E.1
Corbi, N.2
Di Certo, M.G.3
Strimpakos, G.4
Severini, C.5
Onori, A.6
Desantis, A.7
Libri, V.8
Buontempo, S.9
Floridi, A.10
Fanciulli, M.11
Baban, D.12
Davies, K.E.13
Passananti, C.14
-
93
-
-
48449099915
-
Reprograming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor
-
Beltran A.S., Sun X., Lizardi P.M., and Blancafort P. Reprograming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor. Mol. Cancer Ther. 7 (2008) 1080-1090
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1080-1090
-
-
Beltran, A.S.1
Sun, X.2
Lizardi, P.M.3
Blancafort, P.4
-
94
-
-
0037338381
-
Scanning the human genome with combinatorial transcription factor libraries
-
Blancafort P., Magnenat L., and Barbas III C.F. Scanning the human genome with combinatorial transcription factor libraries. Nat. Biotechnol. 21 (2003) 269-274
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 269-274
-
-
Blancafort, P.1
Magnenat, L.2
Barbas III, C.F.3
-
95
-
-
4344685148
-
In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation
-
Magnenat L., Blancafort P., and Barbas III C.F. In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation. J. Mol. Biol. 341 (2004) 635-649
-
(2004)
J. Mol. Biol.
, vol.341
, pp. 635-649
-
-
Magnenat, L.1
Blancafort, P.2
Barbas III, C.F.3
-
96
-
-
3843092833
-
Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library
-
Lee D., Kim Y.H., Kim J.-S., and Seol W. Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library. Nucleic Acids Res. 32 (2004) e116
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Lee, D.1
Kim, Y.H.2
Kim, J.-S.3
Seol, W.4
-
97
-
-
10744225041
-
Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors
-
Park K.-S., Lee D., Lee H., Lee Y., Jang Y.-S., Kim Y.H., Yang H.-Y., Lee S.-I., Soel W., and Kim J.-S. Phenotypic alteration of eukaryotic cells using randomized libraries of artificial transcription factors. Nat. Biotechnol. 21 (2003) 1208-1214
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1208-1214
-
-
Park, K.-S.1
Lee, D.2
Lee, H.3
Lee, Y.4
Jang, Y.-S.5
Kim, Y.H.6
Yang, H.-Y.7
Lee, S.-I.8
Soel, W.9
Kim, J.-S.10
-
98
-
-
23844471938
-
Genetic regrogramming of tumor cells by zinc finger transcription factors
-
Blancafort P., Chen E.I., Gonzalez B., Bergquist S., Zijlstra A., Guthy D., Brachat A., Brakenhoff R.H., Quigley J.P., Erdmann D., and Barbas III C.F. Genetic regrogramming of tumor cells by zinc finger transcription factors. Proc. Natl. Acad. Sci. U.S.A. 102 (2003) 11716-11721
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 11716-11721
-
-
Blancafort, P.1
Chen, E.I.2
Gonzalez, B.3
Bergquist, S.4
Zijlstra, A.5
Guthy, D.6
Brachat, A.7
Brakenhoff, R.H.8
Quigley, J.P.9
Erdmann, D.10
Barbas III, C.F.11
-
99
-
-
41649119943
-
Modulation of drug resistance by artificial transcription factors.
-
Blancafort P., Tschan M.P., Bergquist S., Guthy D., Brachat A., Sheeter D.A., Torbett B.E., Erdmann D., and Barbas III C.F. Modulation of drug resistance by artificial transcription factors. Mol. Cancer Ther. 7 (2008) 688-697
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 688-697
-
-
Blancafort, P.1
Tschan, M.P.2
Bergquist, S.3
Guthy, D.4
Brachat, A.5
Sheeter, D.A.6
Torbett, B.E.7
Erdmann, D.8
Barbas III, C.F.9
-
100
-
-
0024262589
-
Cellular uptake of the Tat protein from human immunodeficiency virus
-
Frankel A.D., and Pabo C.O. Cellular uptake of the Tat protein from human immunodeficiency virus. Cell 55 (1988) 1189-1193
-
(1988)
Cell
, vol.55
, pp. 1189-1193
-
-
Frankel, A.D.1
Pabo, C.O.2
-
101
-
-
13844298046
-
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
-
Gupta B., Levchenko T.S., and Torchilin V.P. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv. Drug Deliv. Rev. 57 (2005) 637-651
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 637-651
-
-
Gupta, B.1
Levchenko, T.S.2
Torchilin, V.P.3
-
102
-
-
0346460957
-
Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Cell-penetrating peptides: tools for intracellular delivery of therapeutics
-
Richard J.P., Melikov K., Vivès E., Ramos C., Verbeure B., Gait M.J., Chernmordik L.V., and Lebleu B. Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Cell-penetrating peptides: tools for intracellular delivery of therapeutics. J. Biol. Chem. 278 (2003) 585-590
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vivès, E.3
Ramos, C.4
Verbeure, B.5
Gait, M.J.6
Chernmordik, L.V.7
Lebleu, B.8
-
103
-
-
85057632884
-
Cell-penetrating peptides: tools for intracellular delivery of therapeutics
-
Deshayes S., Morris M.C., Divita G., and Heitz F. Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Adv. Drug Deliv. Rev. 57 (2005) 637-651
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 637-651
-
-
Deshayes, S.1
Morris, M.C.2
Divita, G.3
Heitz, F.4
-
104
-
-
52649143305
-
Transduction of artificial transcription regulatory proteins into human cells
-
Yun C.-O., Shin H.-C., Kim T.-D., Yoon W.-H., Kang Y.-A., Kwon H.-S., Kim S.K., and Kim J.-S. Transduction of artificial transcription regulatory proteins into human cells. Nucleic Acids Res. 36 (2008) e103
-
(2008)
Nucleic Acids Res.
, vol.36
-
-
Yun, C.-O.1
Shin, H.-C.2
Kim, T.-D.3
Yoon, W.-H.4
Kang, Y.-A.5
Kwon, H.-S.6
Kim, S.K.7
Kim, J.-S.8
-
105
-
-
0032235481
-
Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines
-
Andrei G., Snoeck R., Piette J., Delvenne P., and De Clercq E. Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines. Oncol. Res. 10 (1998) 523-531
-
(1998)
Oncol. Res.
, vol.10
, pp. 523-531
-
-
Andrei, G.1
Snoeck, R.2
Piette, J.3
Delvenne, P.4
De Clercq, E.5
-
106
-
-
0037452693
-
Repression of the HIV-1 5′ LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors
-
Reynolds L., Ullman C., Moore M., Isalan M., West M.J., Clapham P., Klug A., and Choo Y. Repression of the HIV-1 5′ LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 1615-1620
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 1615-1620
-
-
Reynolds, L.1
Ullman, C.2
Moore, M.3
Isalan, M.4
West, M.J.5
Clapham, P.6
Klug, A.7
Choo, Y.8
-
107
-
-
2442536906
-
Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor
-
Segal D.J., Gonçalves J., Eberhardy S., Swan C.H., Torbett B.E., Li X., and Barbas III C.F. Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor. J. Biol. Chem. 279 (2004) 14509-14519
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14509-14519
-
-
Segal, D.J.1
Gonçalves, J.2
Eberhardy, S.3
Swan, C.H.4
Torbett, B.E.5
Li, X.6
Barbas III, C.F.7
-
108
-
-
20444379256
-
Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1
-
Kim Y.-S., Kim J.-M., Jung D.-L., Kang J.-E., Lee S., Kim J.S., Seol W., Shin H.-C., Kwon H.S., Lint C.V., Hernandez N., and Hur M.-W. Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1. J. Biol. Chem. 280 (2005) 21545-21552
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 21545-21552
-
-
Kim, Y.-S.1
Kim, J.-M.2
Jung, D.-L.3
Kang, J.-E.4
Lee, S.5
Kim, J.S.6
Seol, W.7
Shin, H.-C.8
Kwon, H.S.9
Lint, C.V.10
Hernandez, N.11
Hur, M.-W.12
-
109
-
-
33644774584
-
Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site
-
Eberhardy S.R., Goncalves J., Coelho S., Segal D.J., Berkhout B., and Barbas III C.F. Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site. J. Virol. 80 (2006) 2873-2883
-
(2006)
J. Virol.
, vol.80
, pp. 2873-2883
-
-
Eberhardy, S.R.1
Goncalves, J.2
Coelho, S.3
Segal, D.J.4
Berkhout, B.5
Barbas III, C.F.6
-
110
-
-
0037452614
-
Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors
-
Papworth M., Moore M., Isalan M., Minczuk M., Choo Y., and Klug A. Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 1621-1626
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 1621-1626
-
-
Papworth, M.1
Moore, M.2
Isalan, M.3
Minczuk, M.4
Choo, Y.5
Klug, A.6
-
111
-
-
49149097044
-
Zinc finger proteins designed to specifically target duck hepatitis B virus covalently closed circular DNA inhibit viral transcription in tissue culture
-
Zimmerman K.A., Fischer K.P., Joyce M.A., and Tyrrell D.L.J. Zinc finger proteins designed to specifically target duck hepatitis B virus covalently closed circular DNA inhibit viral transcription in tissue culture. J. Virol. 82 (2008) 8013-8021
-
(2008)
J. Virol.
, vol.82
, pp. 8013-8021
-
-
Zimmerman, K.A.1
Fischer, K.P.2
Joyce, M.A.3
Tyrrell, D.L.J.4
-
112
-
-
0025726646
-
Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kB
-
Ruben S.M., Dillon P.J., Schreck R., Henkel T., Chen C.-H., Maher M., Baeuerle P.A., and Rosen C.A. Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kB. Science 251 (1991) 1490-1493
-
(1991)
Science
, vol.251
, pp. 1490-1493
-
-
Ruben, S.M.1
Dillon, P.J.2
Schreck, R.3
Henkel, T.4
Chen, C.-H.5
Maher, M.6
Baeuerle, P.A.7
Rosen, C.A.8
-
113
-
-
0029814513
-
Mad proteins contain a dominant transcription repression domain
-
Ayer D.E., Laherty C.D., Lawrence Q.A., Armstrong A.P., and Eisenman R.N. Mad proteins contain a dominant transcription repression domain. Mol. Cell. Biol. 16 (1992) 5772-5781
-
(1992)
Mol. Cell. Biol.
, vol.16
, pp. 5772-5781
-
-
Ayer, D.E.1
Laherty, C.D.2
Lawrence, Q.A.3
Armstrong, A.P.4
Eisenman, R.N.5
-
114
-
-
0029095176
-
ERF: an ETS domain protein with strong transcriptional represssor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
-
Sgouras D.N., Beal Jr. G.J., Fisher R.J., Blair D.G., and Mavrothalassitis G.J. ERF: an ETS domain protein with strong transcriptional represssor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation. EMBO J. 14 (1995) 4781-4793
-
(1995)
EMBO J.
, vol.14
, pp. 4781-4793
-
-
Sgouras, D.N.1
Beal Jr., G.J.2
Fisher, R.J.3
Blair, D.G.4
Mavrothalassitis, G.J.5
|