-
1
-
-
13944262937
-
Understanding the odd science of aging
-
DOI 10.1016/j.cell.2005.01.027
-
Kirkwood TBL. Understanding the odd science of aging. Cell 120(4), 437-447 (2005). (Pubitemid 40269759)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 437-447
-
-
Kirkwood, T.B.L.1
-
2
-
-
13944282128
-
Sex and death: What is the connection?
-
DOI 10.1016/j.cell.2005.01.026
-
Partridge L, Gems D, Withers DJ. Sex and death: what is the connection? Cell 120(4), 461-472 (2005). (Pubitemid 40269761)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 461-472
-
-
Partridge, L.1
Gems, D.2
Withers, D.J.3
-
3
-
-
34648813720
-
ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
-
DOI 10.1038/nrm2256, PII NRM2256
-
D'Autréaux B, Toledano MB. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat. Rev. Mol. Cell Biol. 8(10), 813-824 (2007). (Pubitemid 47462134)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.10
, pp. 813-824
-
-
D'Autreaux, B.1
Toledano, M.B.2
-
4
-
-
84863611417
-
PiRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans
-
Ashe A, Sapetschnig A, Weick EM et al. piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans. Cell 150(1), 88-99 (2012).
-
(2012)
Cell
, vol.150
, Issue.1
, pp. 88-99
-
-
Ashe, A.1
Sapetschnig, A.2
Weick, E.M.3
-
6
-
-
13944280713
-
Genetic modulation of senescent phenotypes in Homo sapiens
-
DOI 10.1016/j.cell.2005.01.031
-
Martin GM. Genetic modulation of senescent phenotypes in Homo sapiens. Cell 120(4), 523-532 (2005). (Pubitemid 40269766)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 523-532
-
-
Martin, G.M.1
-
7
-
-
70349859881
-
DNA damage, aging, and cancer
-
Hoeijmakers JH. DNA damage, aging, and cancer. N. Engl. J. Med. 361(15), 1475-1485 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, Issue.15
, pp. 1475-1485
-
-
Hoeijmakers, J.H.1
-
8
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
DOI 10.1016/j.cell.2005.02.001
-
Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 120(4), 483-495 (2005). (Pubitemid 40269763)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
9
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
DOI 10.1038/nature02517
-
Trifunovic A, Wredenberg A, Falkenberg M et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429(6990), 417-423 (2004). (Pubitemid 38715133)
-
(2004)
Nature
, vol.429
, Issue.6990
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly-Y, M.7
Gldlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.-G.13
-
10
-
-
77952548782
-
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
-
Ristow M, Zarse K. How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis). Exp. Gerontol. 45(6), 410-418 (2010).
-
(2010)
Exp. Gerontol.
, vol.45
, Issue.6
, pp. 410-418
-
-
Ristow, M.1
Zarse, K.2
-
11
-
-
80053124673
-
"Good" look at free radicals in the aging process
-
Hekimi S, Lapointe J, Wen Y. Taking a "good" look at free radicals in the aging process. Trends Cell Biol. 21(10), 569-576 (2011).
-
(2011)
Trends Cell Biol.
, vol.21
, Issue.10
, pp. 569-576
-
-
Hekimi, S.1
Lapointe, J.2
Wen Taking, Y.A.3
-
12
-
-
84865555655
-
Ageing, genes, environment and epigenetics: What twin studies tell us now, and in the future
-
Steves CJ, Spector TD, Jackson SHD. Ageing, genes, environment and epigenetics: what twin studies tell us now, and in the future. Age Ageing 41(5), 581-586 (2012).
-
(2012)
Age Ageing
, vol.41
, Issue.5
, pp. 581-586
-
-
Steves, C.J.1
Spector, T.D.2
Jackson, S.H.D.3
-
13
-
-
83455179308
-
Genome-environment interactions that modulate aging: Powerful targets for drug discovery
-
de Magalhães JP, Wuttke D, Wood SH, Plank M, Vora C. Genome-environment interactions that modulate aging: powerful targets for drug discovery. Pharmacol. Rev. 64(1), 88-101 (2012).
-
(2012)
Pharmacol. Rev.
, vol.64
, Issue.1
, pp. 88-101
-
-
De Magalhães, J.P.1
Wuttke, D.2
Wood, S.H.3
Plank, M.4
Vora, C.5
-
14
-
-
0016439429
-
DNA modification mechanisms and gene activity during development
-
Holliday R, Pugh JE. DNA modification mechanisms and gene activity during development. Science 187(4173), 226-232 (1975).
-
(1975)
Science
, vol.187
, Issue.4173
, pp. 226-232
-
-
Holliday, R.1
Pugh, J.E.2
-
15
-
-
78650304236
-
Charting histone modifications and the functional organization of mammalian genomes
-
Zhou VW, Goren A, Bernstein BE. Charting histone modifications and the functional organization of mammalian genomes. Nat. Publ. Group 12(1), 7-18 (2011).
-
(2011)
Nat. Publ. Group
, vol.12
, Issue.1
, pp. 7-18
-
-
Zhou, V.W.1
Goren, A.2
Bernstein, B.E.3
-
16
-
-
13944253348
-
Calorie restriction - The SIR2 connection
-
DOI 10.1016/j.cell.2005.01.029
-
Guarente L, Picard F. Calorie restriction - the SIR2 connection. Cell 120(4), 473-482 (2005). (Pubitemid 40269762)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
17
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
DOI 10.1038/nature00829
-
Lin SJ, Kaeberlein M, Andalis AA et al. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418(6895), 344-348 (2002). (Pubitemid 34790687)
-
(2002)
Nature
, vol.418
, Issue.6895
, pp. 344-348
-
-
Lin, S.-J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.-A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
18
-
-
34748850786
-
Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress
-
DOI 10.1016/j.cmet.2007.08.011, PII S1550413107002562
-
Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab. 6(4), 280-293 (2007). (Pubitemid 47468090)
-
(2007)
Cell Metabolism
, vol.6
, Issue.4
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
19
-
-
0037197870
-
Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster
-
DOI 10.1016/S0960-9822(02)00808-4, PII S0960982202008084
-
Pletcher SD, Macdonald SJ, Marguerie R et al. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Curr. Biol. 12(9), 712-723 (2002). (Pubitemid 34455424)
-
(2002)
Current Biology
, vol.12
, Issue.9
, pp. 712-723
-
-
Pletcher, S.D.1
Macdonald, S.J.2
Marguerie, R.3
Certa, U.4
Stearns, S.C.5
Goldstein, D.B.6
Partridge, L.7
-
20
-
-
0022381249
-
Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics
-
Yu BP, Masoro EJ, McMahan CA. Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics. J. Gerontol. 40(6), 657-670 (1985). (Pubitemid 16235349)
-
(1985)
Journals of Gerontology
, vol.40
, Issue.6
, pp. 657-670
-
-
Yu, B.P.1
Masoro, E.J.2
McMahan, C.A.3
-
21
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
Colman RJ, Anderson RM, Johnson SC et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 325(5937), 201-204 (2009).
-
(2009)
Science
, vol.325
, Issue.5937
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
-
22
-
-
84866163081
-
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
-
Mattison JA, Roth GS, Beasley TM et al. Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature 489(7415), 318-321 (2012).
-
(2012)
Nature
, vol.489
, Issue.7415
, pp. 318-321
-
-
Mattison, J.A.1
Roth, G.S.2
Beasley, T.M.3
-
23
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
DOI 10.1016/j.cell.2005.02.002
-
Kenyon C. The plasticity of aging: insights from long-lived mutants. Cell 120(4), 449-460 (2005). (Pubitemid 40269760)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 449-460
-
-
Kenyon, C.1
-
24
-
-
78650758398
-
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
-
Herranz D, Muñoz-Martin M, Cañamero M et al. Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat. Commun. 1, 3 (2010).
-
(2010)
Nat. Commun.
, vol.1
, pp. 3
-
-
Herranz, D.1
Muñoz-Martin, M.2
Cañamero, M.3
-
25
-
-
84868018628
-
Sirtuins as regulators of mammalian aging
-
Naiman S, Kanfi Y, Cohen HY. Sirtuins as regulators of mammalian aging. Aging (Albany NY) 4(8), 521-522 (2012).
-
(2012)
Aging (Albany NY)
, vol.4
, Issue.8
, pp. 521-522
-
-
Naiman, S.1
Kanfi, Y.2
Cohen, H.Y.3
-
26
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett C, Valentini S, Cabreiro F et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477(7365), 482-485 (2011).
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
-
27
-
-
84866160403
-
Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes
-
Wuttke D, Connor R, Vora C et al. Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes. PLoS Genet. 8(8), e1002834 (2012).
-
(2012)
PLoS Genet
, vol.8
, Issue.8
-
-
Wuttke, D.1
Connor, R.2
Vora, C.3
-
28
-
-
24044455869
-
Genome sequencing in microfabricated high-density picolitre reactors
-
DOI 10.1038/nature03959, PII N03959
-
Margulies M, Egholm M, Altman WE et al. Genome sequencing in microfabricated high-density picolitre reactors. Nature 437(7057), 376-380 (2005). (Pubitemid 41613494)
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 376-380
-
-
Margulies, M.1
Egholm, M.2
Altman, W.E.3
Attiya, S.4
Bader, J.S.5
Bemben, L.A.6
Berka, J.7
Braverman, M.S.8
Chen, Y.-J.9
Chen, Z.10
Dewell, S.B.11
Du, L.12
Fierro, J.M.13
Gomes, X.V.14
Godwin, B.C.15
He, W.16
Helgesen, S.17
Ho, C.H.18
Irzyk, G.P.19
Jando, S.C.20
Alenquer, M.L.I.21
Jarvie, T.P.22
Jirage, K.B.23
Kim, J.-B.24
Knight, J.R.25
Lanza, J.R.26
Leamon, J.H.27
Lefkowitz, S.M.28
Lei, M.29
Li, J.30
Lohman, K.L.31
Lu, H.32
Makhijani, V.B.33
McDade, K.E.34
McKenna, M.P.35
Myers, E.W.36
Nickerson, E.37
Nobile, J.R.38
Plant, R.39
Puc, B.P.40
Ronan, M.T.41
Roth, G.T.42
Sarkis, G.J.43
Simons, J.F.44
Simpson, J.W.45
Srinivasan, M.46
Tartaro, K.R.47
Tomasz, A.48
Vogt, K.A.49
Volkmer, G.A.50
Wang, S.H.51
Wang, Y.52
Weiner, M.P.53
Yu, P.54
Begley, R.F.55
Rothberg, J.M.56
more..
-
29
-
-
46449103738
-
A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning
-
DOI 10.1101/gr.076463.108
-
Valouev A, Ichikawa J, Tonthat T et al. A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning. Genome Res. 18(7), 1051-1063 (2008). (Pubitemid 351931156)
-
(2008)
Genome Research
, vol.18
, Issue.7
, pp. 1051-1063
-
-
Valouev, A.1
Ichikawa, J.2
Tonthat, T.3
Stuart, J.4
Ranade, S.5
Peckham, H.6
Zeng, K.7
Malek, J.A.8
Costa, G.9
McKernan, K.10
Sidow, A.11
Fire, A.12
Johnson, S.M.13
-
30
-
-
79960556965
-
Epigenome-wide association studies for common human diseases
-
Rakyan VK, Down TA, Balding DJ, Beck S. Epigenome-wide association studies for common human diseases. Nat. Publ. Group 12(8), 529-541 (2011).
-
(2011)
Nat. Publ. Group
, vol.12
, Issue.8
, pp. 529-541
-
-
Rakyan, V.K.1
Down, T.A.2
Balding, D.J.3
Beck, S.4
-
31
-
-
77952553604
-
Next-generation sequencing in aging research: Emerging applications, problems, pitfalls and possible solutions
-
de Magalhães JP, Finch CE, Janssens G. Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions. Ageing Res. Rev. 9(3), 315-323 (2010).
-
(2010)
Ageing Res. Rev.
, vol.9
, Issue.3
, pp. 315-323
-
-
De Magalhães, J.P.1
Finch, C.E.2
Janssens, G.3
-
32
-
-
0023057540
-
Caenorhabditis elegans DNA does not contain 5methylcytosine at any time during development or aging
-
Simpson VJ, Johnson TE, Hammen RF. Caenorhabditis elegans DNA does not contain 5methylcytosine at any time during development or aging. Nucleic Acids Res. 14(16), 6711-6719 (1986).
-
(1986)
Nucleic Acids Res
, vol.14
, Issue.16
, pp. 6711-6719
-
-
Simpson, V.J.1
Johnson, T.E.2
Hammen, R.F.3
-
33
-
-
79952265169
-
A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues
-
Pai AA, Bell JT, Marioni JC, Pritchard JK, Gilad Y. A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet. 7(2), e1001316 (2011).
-
(2011)
PLoS Genet.
, vol.7
, Issue.2
-
-
Pai, A.A.1
Bell, J.T.2
Marioni, J.C.3
Pritchard, J.K.4
Gilad, Y.5
-
34
-
-
77957708999
-
Single molecule sequencing with a HeliScope genetic analysis system
-
Chapter 7, Unit 7.10
-
Thompson JF, Steinmann KE. Single molecule sequencing with a HeliScope genetic analysis system. Curr. Protoc. Mol. Biol. Chapter 7, Unit 7.10 (2010).
-
(2010)
Curr. Protoc. Mol. Biol.
-
-
Thompson, J.F.1
Steinmann, K.E.2
-
35
-
-
84858150703
-
MethylomeDB: A database of DNA methylation profiles of the brain
-
Xin Y, Chanrion B, O'Donnell AH et al. MethylomeDB: a database of DNA methylation profiles of the brain. Nucleic Acids Res. 40, D1245-D1249 (2011).
-
(2011)
Nucleic Acids Res
, vol.40
-
-
Xin, Y.1
Chanrion, B.2
O'Donnell, A.H.3
-
36
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 462(7271), 315-322 (2009).
-
(2009)
Nature
, vol.462
, Issue.7271
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
37
-
-
80053572636
-
Evidence for non-CpG methylation in mammals
-
Yan J, Zierath JR, Barrès R. Evidence for non-CpG methylation in mammals. Exp. Cell Res. 317(18), 2555-2561 (2011).
-
(2011)
Exp. Cell Res.
, vol.317
, Issue.18
, pp. 2555-2561
-
-
Yan, J.1
Zierath, J.R.2
Barrès, R.3
-
38
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases [1]
-
DOI 10.1038/890
-
Okano M, Xie S, Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine5) methyltransferases. Nat. Genet. 19(3), 219-220 (1998). (Pubitemid 28309328)
-
(1998)
Nature Genetics
, vol.19
, Issue.3
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
39
-
-
0035933337
-
Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: The enzyme modifies DNA in a non-processive manner and also methylates non-CpA sites
-
DOI 10.1006/jmbi.2001.4710
-
Gowher H, Jeltsch A. Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites. J. Mol. Biol. 309(5), 1201-1208 (2001). (Pubitemid 32623318)
-
(2001)
Journal of Molecular Biology
, vol.309
, Issue.5
, pp. 1201-1208
-
-
Gowher, H.1
Jeltsch, A.2
-
40
-
-
84863889319
-
In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases
-
Arand J, Spieler D, Karius T et al. In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases. PLoS Genet. 8(6), e1002750 (2012).
-
(2012)
PLoS Genet
, vol.8
, Issue.6
-
-
Arand, J.1
Spieler, D.2
Karius, T.3
-
41
-
-
0036415141
-
Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA
-
DOI 10.1046/j.1432-1033.2002.03198.x
-
Fatemi M, Hermann A, Gowher H, Jeltsch A. Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA. Eur. J. Biochem. 269(20), 4981-4984 (2002). (Pubitemid 35279011)
-
(2002)
European Journal of Biochemistry
, vol.269
, Issue.20
, pp. 4981-4984
-
-
Fatemi, M.1
Hermann, A.2
Gowher, H.3
Jeltsch, A.4
-
42
-
-
0036135014
-
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements
-
DOI 10.1128/MCB.22.2.480-491.2002
-
Liang G, Chan MF, Tomigahara Y et al. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol. Cell Biol. 22(2), 480-491 (2002). (Pubitemid 34027493)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.2
, pp. 480-491
-
-
Liang, G.1
Chan, M.F.2
Tomigahara, Y.3
Tsai, Y.C.4
Gonzales, F.A.5
Li, E.6
Laird, P.W.7
Jones, P.A.8
-
43
-
-
66149146320
-
Conversion of 5methylcytosine to 5hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y et al. Conversion of 5methylcytosine to 5hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324(5929), 930-935 (2009).
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
44
-
-
79956308473
-
Genome-wide mapping of 5hydroxymethylcytosine in embryonic stem cells
-
Pastor WA, Pape UJ, Huang Y et al. Genome-wide mapping of 5hydroxymethylcytosine in embryonic stem cells. Nature 473(7347), 394-397 (2011).
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
-
45
-
-
84861990517
-
Base-resolution analysis of 5hydroxymethylcytosine in the mammalian genome
-
Yu M, Hon GC, Szulwach KE et al. Base-resolution analysis of 5hydroxymethylcytosine in the mammalian genome. Cell 149(6), 1368-1380 (2012).
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
-
46
-
-
80052461558
-
Tet proteins can convert 5methylcytosine to 5formylcytosine and 5carboxylcytosine
-
Ito S, Shen L, Dai Q et al. Tet proteins can convert 5methylcytosine to 5formylcytosine and 5carboxylcytosine. Science 333(6047), 1300-1303 (2011).
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
-
47
-
-
80052495940
-
Tet-mediated formation of 5carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z et al. Tet-mediated formation of 5carboxylcytosine and its excision by TDG in mammalian DNA. Science 333(6047), 1303-1307 (2011).
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
-
48
-
-
79956323623
-
Dynamic regulation of 5hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G, Branco MR, Seisenberger S et al. Dynamic regulation of 5hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473(7347), 398-402 (2011).
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
-
49
-
-
84862210732
-
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
-
Davies MN, Volta M, Pidsley R et al. Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol. 13(6), R43 (2012).
-
(2012)
Genome Biol
, vol.13
, Issue.6
-
-
Davies, M.N.1
Volta, M.2
Pidsley, R.3
-
50
-
-
77958605856
-
Epigenetic choreographers of neurogenesis in the adult mammalian brain
-
Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat. Neurosci. 13(11), 1338-1344 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, Issue.11
, pp. 1338-1344
-
-
Ma, D.K.1
Marchetto, M.C.2
Guo, J.U.3
Ming, G.L.4
Gage, F.H.5
Song, H.6
-
51
-
-
0026658662
-
Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA
-
Meehan RR, Lewis JD, Bird AP. Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. Nucleic Acids Res. 20(19), 5085-5092 (1992).
-
(1992)
Nucleic Acids Res
, vol.20
, Issue.19
, pp. 5085-5092
-
-
Meehan, R.R.1
Lewis, J.D.2
Bird, A.P.3
-
52
-
-
0025981310
-
Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region
-
Prendergast GC, Ziff EB. Methylation-sensitive sequence-specific DNA binding by the cMyc basic region. Science 251(4990), 186-189 (1991). (Pubitemid 21916865)
-
(1991)
Science
, vol.251
, Issue.4990
, pp. 186-189
-
-
Prendergast, G.C.1
Ziff, E.B.2
-
53
-
-
77954362183
-
Examination of the specificity of DNA methylation profiling techniques towards 5methylcytosine and 5hydroxymethylcytosine
-
Jin SG, Kadam S, Pfeifer GP. Examination of the specificity of DNA methylation profiling techniques towards 5methylcytosine and 5hydroxymethylcytosine. Nucleic Acids Res. 38(11), e125 (2010).
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.11
-
-
Jin, S.G.1
Kadam, S.2
Pfeifer, G.P.3
-
54
-
-
1042272175
-
Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: Implications for X chromosome inactivation
-
Wolf SF, Jolly DJ, Lunnen KD, Friedmann T, Migeon BR. Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for Xchromosome inactivation. Proc. Natl Acad. Sci. USA 81(9), 2806-2810 (1984). (Pubitemid 14123803)
-
(1984)
Proceedings of the National Academy of Sciences of the United States of America
, vol.81
, Issue.9
, pp. 2806-2810
-
-
Wolf, S.F.1
Jolly, D.J.2
Lunnen, K.D.3
-
55
-
-
40749109894
-
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
-
DOI 10.1038/nature06745, PII NATURE06745
-
Cokus SJ, Feng S, Zhang X et al. Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature 452(7184), 215-219 (2008). (Pubitemid 351380251)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 215-219
-
-
Cokus, S.J.1
Feng, S.2
Zhang, X.3
Chen, Z.4
Merriman, B.5
Haudenschild, C.D.6
Pradhan, S.7
Nelson, S.F.8
Pellegrini, M.9
Jacobsen, S.E.10
-
56
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
Maunakea AK, Nagarajan RP, Bilenky M et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 466(7303), 253-257 (2010).
-
(2010)
Nature
, vol.466
, Issue.7303
, pp. 253-257
-
-
Maunakea, A.K.1
Nagarajan, R.P.2
Bilenky, M.3
-
57
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent L, Wong E, Li G et al. Dynamic changes in the human methylome during differentiation. Genome Res. 20(3), 320-331 (2010).
-
(2010)
Genome Res
, vol.20
, Issue.3
, pp. 320-331
-
-
Laurent, L.1
Wong, E.2
Li, G.3
-
58
-
-
84857071275
-
High resolution methylome map of rat indicates role of intragenic DNA methylation in identification of coding region
-
Sati S, Tanwar VS, Kumar KA et al. High resolution methylome map of rat indicates role of intragenic DNA methylation in identification of coding region. PLoS ONE 7(2), e31621 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.2
-
-
Sati, S.1
Tanwar, V.S.2
Kumar, K.A.3
-
59
-
-
77954171220
-
Contrasting chromatin organization of CpG islands and exons in the human genome
-
Choi JK. Contrasting chromatin organization of CpG islands and exons in the human genome. Genome Biol. 11(7), R70 (2010).
-
(2010)
Genome Biol
, vol.11
, Issue.7
-
-
Choi, J.K.1
-
60
-
-
80052640352
-
Deciphering a methylome: What can we read into patterns of DNA methylation?
-
Flores KB, Amdam GV. Deciphering a methylome: what can we read into patterns of DNA methylation? J. Exp. Biol. 214(Pt 19), 3155-3163 (2011).
-
(2011)
J. Exp. Biol.
, vol.214
, Issue.PART 19
, pp. 3155-3163
-
-
Flores, K.B.1
Amdam, G.V.2
-
61
-
-
79958071640
-
ICF syndrome mutations cause a broad spectrum of biochemical defects in DNMT3B-mediated de novo DNA methylation
-
Moarefi AH, Chédin F. ICF syndrome mutations cause a broad spectrum of biochemical defects in DNMT3B-mediated de novo DNA methylation. J. Mol. Biol. 409(5), 758-772 (2011).
-
(2011)
J. Mol. Biol.
, vol.409
, Issue.5
, pp. 758-772
-
-
Moarefi, A.H.1
Chédin, F.2
-
62
-
-
84355163093
-
DNA-binding factors shape the mouse methylome at distal regulatory regions
-
Stadler MB, Murr R, Burger L et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature 480(7378), 490-495 (2011).
-
(2011)
Nature
, vol.480
, Issue.7378
, pp. 490-495
-
-
Stadler, M.B.1
Murr, R.2
Burger, L.3
-
63
-
-
67650090496
-
Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
-
Schmidl C, Klug M, Boeld TJ et al. Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity. Genome Res. 19(7), 1165-1174 (2009).
-
(2009)
Genome Res.
, vol.19
, Issue.7
, pp. 1165-1174
-
-
Schmidl, C.1
Klug, M.2
Boeld, T.J.3
-
64
-
-
0034713375
-
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
-
DOI 10.1038/35013100
-
Bell AC, Felsenfeld G. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 405(6785), 482-485 (2000). (Pubitemid 30367427)
-
(2000)
Nature
, vol.405
, Issue.6785
, pp. 482-485
-
-
Bell, A.C.1
Felsenfeld, G.2
-
65
-
-
17144369504
-
Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L
-
DOI 10.1074/jbc.M413412200
-
Gowher H, Liebert K, Hermann A, Xu G, Jeltsch A. Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L. J. Biol. Chem. 280(14), 13341-13348 (2005). (Pubitemid 40517220)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.14
, pp. 13341-13348
-
-
Gowher, H.1
Liebert, K.2
Hermann, A.3
Xu, G.4
Jeltsch, A.5
-
66
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
DOI 10.1038/nature06397, PII NATURE06397
-
Sharif J, Muto M, Takebayashi SI et al. The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450(7171), 908-912 (2007). (Pubitemid 350231331)
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.-I.3
Suetake, I.4
Iwamatsu, A.5
Endo, T.A.6
Shinga, J.7
Mizutani-Koseki, Y.8
Toyoda, T.9
Okamura, K.10
Tajima, S.11
Mitsuya, K.12
Okano, M.13
Koseki, H.14
-
67
-
-
70449093724
-
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
-
Meilinger D, Fellinger K, Bultmann S et al. Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells. EMBO Rep. 10(11), 1259-1264 (2009).
-
(2009)
EMBO Rep
, vol.10
, Issue.11
, pp. 1259-1264
-
-
Meilinger, D.1
Fellinger, K.2
Bultmann, S.3
-
68
-
-
80054994283
-
Identification of genetic elements that autonomously determine DNA methylation states
-
Lienert F, Wirbelauer C, Som I, Dean A, Mohn F, Schübeler D. Identification of genetic elements that autonomously determine DNA methylation states. Nat. Genet. 43(11), 1091-1097 (2011).
-
(2011)
Nat. Genet.
, vol.43
, Issue.11
, pp. 1091-1097
-
-
Lienert, F.1
Wirbelauer, C.2
Som, I.3
Dean, A.4
Mohn, F.5
Schübeler, D.6
-
69
-
-
84867288158
-
Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island
-
Zhang Y, Shu J, Si J, Shen L, Estecio MR, Issa JP. Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island. Nucleic Acids Res. 40(15), 7257-7268 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
, Issue.15
, pp. 7257-7268
-
-
Zhang, Y.1
Shu, J.2
Si, J.3
Shen, L.4
Estecio, M.R.5
Issa, J.P.6
-
70
-
-
84863233758
-
Sequences sufficient for programming imprinted germline DNA methylation defined
-
Park YJ, Herman H, Gao Y et al. Sequences sufficient for programming imprinted germline DNA methylation defined. PLoS ONE 7(3), e33024 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.3
-
-
Park, Y.J.1
Herman, H.2
Gao, Y.3
-
71
-
-
84863248732
-
The influence of cis-regulatory elements on DNA methylation fidelity
-
Teng M, Balch C, Liu Y et al. The influence of cis-regulatory elements on DNA methylation fidelity. PLoS ONE 7(3), e32928 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.3
-
-
Teng, M.1
Balch, C.2
Liu, Y.3
-
72
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M, Luo H, Lee S et al. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146(6), 1016-1028 (2011).
-
(2011)
Cell
, vol.146
, Issue.6
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
-
73
-
-
23844519339
-
A high-resolution map of active promoters in the human genome
-
DOI 10.1038/nature03877
-
Kim TH, Barrera LO, Zheng M et al. A high-resolution map of active promoters in the human genome. Nature 436(7052), 876-880 (2005). (Pubitemid 41160649)
-
(2005)
Nature
, vol.436
, Issue.7052
, pp. 876-880
-
-
Kim, T.H.1
Barrera, L.O.2
Zheng, M.3
Qu, C.4
Singer, M.A.5
Richmond, T.A.6
Wu, Y.7
Green, R.D.8
Ren, B.9
-
74
-
-
14644406272
-
Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping
-
DOI 10.1101/gad.1272505
-
Roh TY, Cuddapah S, Zhao K. Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping. Genes Dev. 19(5), 542-552 (2005). (Pubitemid 40314987)
-
(2005)
Genes and Development
, vol.19
, Issue.5
, pp. 542-552
-
-
Roh, T.-Y.1
Cuddapah, S.2
Zhao, K.3
-
75
-
-
2642570305
-
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
-
DOI 10.1101/gad.1198204
-
Schübeler D, MacAlpine DM, Scalzo D et al. The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. Genes Dev. 18(11), 1263-1271 (2004). (Pubitemid 38720594)
-
(2004)
Genes and Development
, vol.18
, Issue.11
, pp. 1263-1271
-
-
Schubeler, D.1
MacAlpine, D.M.2
Scalzo, D.3
Wirbelauer, C.4
Kooperberg, C.5
Van Leeuwen, F.6
Gottschling, D.E.7
O'Neill, L.P.8
Turner, B.M.9
Delrow, J.10
Bell, S.P.11
Groudine, M.12
-
76
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
DOI 10.1038/ng.154, PII NG154
-
Wang Z, Zang C, Rosenfeld JA et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat. Genet. 40(7), 897-903 (2008). (Pubitemid 351913645)
-
(2008)
Nature Genetics
, vol.40
, Issue.7
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
Schones, D.E.4
Barski, A.5
Cuddapah, S.6
Cui, K.7
Roh, T.-Y.8
Peng, W.9
Zhang, M.Q.10
Zhao, K.11
-
77
-
-
84865761246
-
Modeling gene expression using chromatin features in various cellular contexts
-
Dong X, Greven MC, Kundaje A et al. Modeling gene expression using chromatin features in various cellular contexts. Genome Biol. 13(9), R53 (2012).
-
(2012)
Genome Biol
, vol.13
, Issue.9
-
-
Dong, X.1
Greven, M.C.2
Kundaje, A.3
-
78
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
ENCODE Project Consortium
-
ENCODE Project Consortium, Dunham I, Kundaje A, Aldred SF et al. An integrated encyclopedia of DNA elements in the human genome. Nature 489(7414), 57-74 (2012).
-
(2012)
Nature
, vol.489
, Issue.7414
, pp. 57-74
-
-
Dunham, I.1
Kundaje, A.2
Aldred, S.F.3
-
79
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
DOI 10.1101/gad.300704
-
Schotta G, Lachner M, Sarma K et al. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 18(11), 1251-1262 (2004). (Pubitemid 38720593)
-
(2004)
Genes and Development
, vol.18
, Issue.11
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
Reinberg, D.7
Jenuwein, T.8
-
80
-
-
79959484677
-
Signals and combinatorial functions of histone modifications
-
Suganuma T, Workman JL. Signals and combinatorial functions of histone modifications. Annu. Rev. Biochem. 80, 473-499 (2011).
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 473-499
-
-
Suganuma, T.1
Workman, J.L.2
-
81
-
-
78751611793
-
Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation
-
Jin Q, Yu LR, Wang L et al. Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation. EMBO J. 30(2), 249-262 (2011).
-
(2011)
EMBO J
, vol.30
, Issue.2
, pp. 249-262
-
-
Jin, Q.1
Yu, L.R.2
Wang, L.3
-
82
-
-
0344196937
-
Aging, cancer and nutrition: The DNA methylation connection
-
DOI 10.1016/j.mad.2003.08.001
-
Liu L, Wylie RC, Andrews LG, Tollefsbol TO. Aging, cancer and nutrition: the DNA methylation connection. Mech. Ageing Dev. 124(10-12), 989-998 (2003). (Pubitemid 37500825)
-
(2003)
Mechanisms of Ageing and Development
, vol.124
, Issue.10-12
, pp. 989-998
-
-
Liu, L.1
Wylie, R.C.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
83
-
-
84863012853
-
Insufficient DNA methylation affects healthy aging and promotes age-related health problems
-
Liu L, van Groen T, Kadish I et al. Insufficient DNA methylation affects healthy aging and promotes age-related health problems. Clin. Epigenetics 2(2), 349-360 (2011).
-
(2011)
Clin. Epigenetics
, vol.2
, Issue.2
, pp. 349-360
-
-
Liu, L.1
Van Groen, T.2
Kadish, I.3
-
84
-
-
84862979818
-
Distinct DNA methylomes of newborns and centenarians
-
Heyn H, Li N, Ferreira HJ et al. Distinct DNA methylomes of newborns and centenarians. Proc. Natl Acad. Sci. USA 109(26), 10522-10527 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, Issue.26
, pp. 10522-10527
-
-
Heyn, H.1
Li, N.2
Ferreira, H.J.3
-
85
-
-
45849127657
-
Intra-individual change over time in DNA methylation with familial clustering
-
DOI 10.1001/jama.299.24.2877
-
Bjornsson HT, Sigurdsson MI, Fallin MD et al. Intra-individual change over time in DNA methylation with familial clustering. JAMA 299(24), 2877-2883 (2008). (Pubitemid 351930887)
-
(2008)
JAMA - Journal of the American Medical Association
, vol.299
, Issue.24
, pp. 2877-2883
-
-
Bjornsson, H.T.1
Sigurdsson, M.I.2
Fallin, M.D.3
Irizarry, R.A.4
Aspelund, T.5
Cui, H.6
Yu, W.7
Rongione, M.A.8
Ekstrom, T.J.9
Harris, T.B.10
Launer, L.J.11
Eiriksdottir, G.12
Leppert, M.F.13
Sapienza, C.14
Gudnason, V.15
Feinberg, A.P.16
-
86
-
-
84890166425
-
Role of epigenetics in human aging and longevity: Genome-wide DNA methylation profile in centenarians and centenarians' offspring
-
doi:10.1007/s11357-012-9463-1 Epub ahead of print
-
Gentilini D, Mari D, Castaldi D et al. Role of epigenetics in human aging and longevity: genome-wide DNA methylation profile in centenarians and centenarians' offspring. Age (Dordr.) doi:10.1007/s11357-012-9463-1 (2012) (Epub ahead of print).
-
(2012)
Age (Dordr.)
-
-
Gentilini, D.1
Mari, D.2
Castaldi, D.3
-
87
-
-
60849100524
-
Decline in genomic DNA methylation through aging in a cohort of elderly subjects
-
Bollati V, Schwartz J, Wright R et al. Decline in genomic DNA methylation through aging in a cohort of elderly subjects. Mech. Ageing Dev. 130(4), 234-239 (2009).
-
(2009)
Mech. Ageing Dev.
, vol.130
, Issue.4
, pp. 234-239
-
-
Bollati, V.1
Schwartz, J.2
Wright, R.3
-
88
-
-
77953825565
-
DNA methylation as a biomarker for cardiovascular disease risk
-
Kim M, Long TI, Arakawa K, Wang R, Yu MC, Laird PW. DNA methylation as a biomarker for cardiovascular disease risk. PLoS ONE 5(3), e9692 (2010).
-
(2010)
PLoS ONE
, vol.5
, Issue.3
-
-
Kim, M.1
Long, T.I.2
Arakawa, K.3
Wang, R.4
Yu, M.C.5
Laird, P.W.6
-
89
-
-
40949160813
-
Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: A case- control study
-
Moore LE, Pfeiffer RM, Poscablo C et al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case- control study. Lancet Oncol. 9(4), 359-366 (2008).
-
(2008)
Lancet Oncol
, vol.9
, Issue.4
, pp. 359-366
-
-
Moore, L.E.1
Pfeiffer, R.M.2
Poscablo, C.3
-
90
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
DOI 10.1038/ng1909, PII NG1909
-
Eckhardt F, Lewin J, Cortese R et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat. Genet. 38(12), 1378-1385 (2006). (Pubitemid 44837559)
-
(2006)
Nature Genetics
, vol.38
, Issue.12
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
Rakyan, V.K.4
Attwood, J.5
Burger, M.6
Burton, J.7
Cox, T.V.8
Davies, R.9
Down, T.A.10
Haefliger, C.11
Horton, R.12
Howe, K.13
Jackson, D.K.14
Kunde, J.15
Koenig, C.16
Liddle, J.17
Niblett, D.18
Otto, T.19
Pettett, R.20
Seemann, S.21
Thompson, C.22
West, T.23
Rogers, J.24
Olek, A.25
Berlin, K.26
Beck, S.27
more..
-
91
-
-
33845332711
-
DNA hypomethylation and human diseases
-
DOI 10.1016/j.bbcan.2006.08.007, PII S0304419X06000564
-
Wilson AS, Power BE, Molloy PL. DNA hypomethylation and human diseases. Biochim. Biophys. Acta 1775(1), 138-162 (2007). (Pubitemid 44881198)
-
(2007)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1775
, Issue.1
, pp. 138-162
-
-
Wilson, A.S.1
Power, B.E.2
Molloy, P.L.3
-
92
-
-
0347991998
-
Age-associated activation of epigenetically repressed genes in the mouse
-
Bennett-Baker PE, Wilkowski J, Burke DT. Age-associated activation of epigenetically repressed genes in the mouse. Genetics 165(4), 2055-2062 (2003). (Pubitemid 38040289)
-
(2003)
Genetics
, vol.165
, Issue.4
, pp. 2055-2062
-
-
Bennett-Baker, P.E.1
Wilkowski, J.2
Burke, D.T.3
-
93
-
-
84930478542
-
Aging and epigenetics: Longitudinal changes in gene-specific DNA methylation
-
Madrigano J, Baccarelli A, Mittleman MA et al. Aging and epigenetics: longitudinal changes in gene-specific DNA methylation. Epigenetics 7(1), 63-70 (2012).
-
(2012)
Epigenetics
, vol.7
, Issue.1
, pp. 63-70
-
-
Madrigano, J.1
Baccarelli, A.2
Mittleman, M.A.3
-
94
-
-
33747172229
-
Inflamm-aging, cytokines and aging: State of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology
-
DOI 10.2174/138161206777947470
-
Salvioli S, Capri M, Valensin S et al. Inflamm-aging, cytokines and aging: state of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology. Curr. Pharm. Des. 12(24), 3161-3171 (2006). (Pubitemid 44227576)
-
(2006)
Current Pharmaceutical Design
, vol.12
, Issue.24
, pp. 3161-3171
-
-
Salvioli, S.1
Capri, M.2
Valensin, S.3
Tieri, P.4
Monti, D.5
Ottaviani, E.6
Franceschi, C.7
-
95
-
-
81455131478
-
Age-related loss of CpG methylation in the tumour necrosis factor promoter
-
Gowers IR, Walters K, Kiss-Toth E, Read RC, Duff GW, Wilson AG. Age-related loss of CpG methylation in the tumour necrosis factor promoter. Cytokine 56(3), 792-797 (2011).
-
(2011)
Cytokine
, vol.56
, Issue.3
, pp. 792-797
-
-
Gowers, I.R.1
Walters, K.2
Kiss-Toth, E.3
Read, R.C.4
Duff, G.W.5
Wilson, A.G.6
-
96
-
-
77950657253
-
Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains
-
Rakyan VK, Down TA, Maslau S et al. Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains. Genome Res. 20(4), 434-439 (2010).
-
(2010)
Genome Res
, vol.20
, Issue.4
, pp. 434-439
-
-
Rakyan, V.K.1
Down, T.A.2
Maslau, S.3
-
97
-
-
70149099610
-
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
-
Christensen BC, Houseman EA, Marsit CJ et al. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet. 5(8), e1000602 (2009).
-
(2009)
PLoS Genet.
, vol.5
, Issue.8
-
-
Christensen, B.C.1
Houseman, E.A.2
Marsit, C.J.3
-
98
-
-
79952036163
-
Distinct DNA methylation changes highly correlated with chronological age in the human brain
-
Hernandez DG, Nalls MA, Gibbs JR et al. Distinct DNA methylation changes highly correlated with chronological age in the human brain. Hum. Mol. Genet. 20(6), 1164-1172 (2011).
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.6
, pp. 1164-1172
-
-
Hernandez, D.G.1
Nalls, M.A.2
Gibbs, J.R.3
-
99
-
-
41349109107
-
The emergence of DNA methylation as a key modulator of aberrant cell death in prostate cancer
-
DOI 10.1677/ERC-07-0208
-
Murphy TM, Perry AS, Lawler M. The emergence of DNA methylation as a key modulator of aberrant cell death in prostate cancer. Endocr. Relat. Cancer 15(1), 11-25 (2008). (Pubitemid 351449724)
-
(2008)
Endocrine-Related Cancer
, vol.15
, Issue.1
, pp. 11-25
-
-
Murphy, T.M.1
Perry, A.S.2
Lawler, M.3
-
100
-
-
34648816970
-
Cellular senescence and chromatin structure
-
DOI 10.1007/s00412-007-0115-7
-
Funayama R, Ishikawa F. Cellular senescence and chromatin structure. Chromosoma 116(5), 431-440 (2007). (Pubitemid 47456911)
-
(2007)
Chromosoma
, vol.116
, Issue.5
, pp. 431-440
-
-
Funayama, R.1
Ishikawa, F.2
-
101
-
-
79953677172
-
Apoptosis and aging: Increased resistance to apoptosis enhances the aging process
-
Salminen A, Ojala J, Kaarniranta K. Apoptosis and aging: increased resistance to apoptosis enhances the aging process. Cell Mol. Life Sci. 68(6), 1021-1031 (2011).
-
(2011)
Cell Mol. Life Sci.
, vol.68
, Issue.6
, pp. 1021-1031
-
-
Salminen, A.1
Ojala, J.2
Kaarniranta, K.3
-
103
-
-
77953191946
-
Aging and chronic sun exposure cause distinct epigenetic changes in human skin
-
Grönniger E, Weber B, Heil O et al. Aging and chronic sun exposure cause distinct epigenetic changes in human skin. PLoS Genet. 6(5), e1000971 (2010).
-
(2010)
PLoS Genet.
, vol.6
, Issue.5
-
-
Grönniger, E.1
Weber, B.2
Heil, O.3
-
104
-
-
33748939095
-
Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia
-
DOI 10.1111/j.1349-7006.2006.00302.x
-
So K, Tamura G, Honda T et al. Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia. Cancer Sci. 97(11), 1155-1158 (2006). (Pubitemid 44430640)
-
(2006)
Cancer Science
, vol.97
, Issue.11
, pp. 1155-1158
-
-
So, K.1
Tamura, G.2
Honda, T.3
Homma, N.4
Waki, T.5
Togawa, N.6
Nishizuka, S.7
Motoyama, T.8
-
105
-
-
84864946547
-
Postnatal development- and age-related changes in DNA-methylation patterns in the human genome
-
Salpea P, Russanova VR, Hirai TH et al. Postnatal development- and age-related changes in DNA-methylation patterns in the human genome. Nucleic Acids Res. 40(14), 6477-6494 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.14
, pp. 6477-6494
-
-
Salpea, P.1
Russanova, V.R.2
Hirai, T.H.3
-
106
-
-
84862994335
-
Effect of aging on 5hydroxymethylcytosine in the mouse hippocampus
-
Chen H, Dzitoyeva S, Manev H. Effect of aging on 5hydroxymethylcytosine in the mouse hippocampus. Restor. Neurol. Neurosci. 30(3), 237-245 (2012).
-
(2012)
Restor. Neurol. Neurosci.
, vol.30
, Issue.3
, pp. 237-245
-
-
Chen, H.1
Dzitoyeva, S.2
Manev, H.3
-
107
-
-
82255192294
-
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
-
Szulwach KE, Li X, Li Y et al. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat. Neurosci. 14(12), 1607-1616 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, Issue.12
, pp. 1607-1616
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
-
108
-
-
0141839825
-
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
-
DOI 10.1023/A:1025548623524
-
Casillas MA, Lopatina N, Andrews LG, Tollefsbol TO. Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts. Mol. Cell Biochem. 252(1-2), 33-43 (2003). (Pubitemid 37220730)
-
(2003)
Molecular and Cellular Biochemistry
, vol.252
, Issue.1-2
, pp. 33-43
-
-
Casillas Jr., M.A.1
Lopatina, N.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
109
-
-
77649342230
-
Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes
-
Li Y, Liu Y, Strickland FM, Richardson B. Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes. Exp. Gerontol. 45(4), 312-322 (2010).
-
(2010)
Exp. Gerontol.
, vol.45
, Issue.4
, pp. 312-322
-
-
Li, Y.1
Liu, Y.2
Strickland, F.M.3
Richardson, B.4
-
110
-
-
84864461542
-
Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities
-
Oliveira AMM, Hemstedt TJ, Bading H. Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities. Nat. Neurosci. 15(8), 1111-1113 (2012).
-
(2012)
Nat. Neurosci.
, vol.15
, Issue.8
, pp. 1111-1113
-
-
Amm, O.1
Hemstedt, T.J.2
Bading, H.3
-
111
-
-
80053270332
-
Neuronal activity modifies the DNA methylation landscape in the adult brain
-
Guo JU, Ma DK, Mo H et al. Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat. Neurosci. 14(10), 1345-1351 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, Issue.10
, pp. 1345-1351
-
-
Guo, J.U.1
Ma, D.K.2
Mo, H.3
-
112
-
-
77649240380
-
Widespread and tissue specific age-related DNA methylation changes in mice
-
Maegawa S, Hinkal G, Kim HS et al. Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res. 20(3), 332-340 (2010).
-
(2010)
Genome Res.
, vol.20
, Issue.3
, pp. 332-340
-
-
Maegawa, S.1
Hinkal, G.2
Kim, H.S.3
-
113
-
-
84856791176
-
Population-specificity of human DNA methylation
-
Fraser HB, Lam L, Neumann S, Kobor MS. Population-specificity of human DNA methylation. Genome Biol. 13(2), R8 (2012).
-
(2012)
Genome Biol
, vol.13
, Issue.2
-
-
Fraser, H.B.1
Lam, L.2
Neumann, S.3
Kobor, M.S.4
-
115
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
DOI 10.1073/pnas.0500398102
-
Fraga MF, Ballestar E, Paz MF et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl Acad. Sci. USA 102(30), 10604-10609 (2005). (Pubitemid 41061601)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.30
, pp. 10604-10609
-
-
Fraga, M.F.1
Ballestar, E.2
Paz, M.F.3
Ropero, S.4
Setien, F.5
Ballestar, M.L.6
Heine-Suner, D.7
Cigudosa, J.C.8
Urioste, M.9
Benitez, J.10
Boix-Chornet, M.11
Sanchez-Aguilera, A.12
Ling, C.13
Carlsson, E.14
Poulsen, P.15
Vaag, A.16
Stephan, Z.17
Spector, T.D.18
Wu, Y.-Z.19
Plass, C.20
Esteller, M.21
more..
-
116
-
-
84864019015
-
Epigenetic variation during the adult lifespan: Cross-sectional and longitudinal data on monozygotic twin pairs
-
Talens RP, Christensen K, Putter H et al. Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. Aging Cell 11(4), 694-703 (2012).
-
(2012)
Aging Cell
, vol.11
, Issue.4
, pp. 694-703
-
-
Talens, R.P.1
Christensen, K.2
Putter, H.3
-
117
-
-
0034905743
-
Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: Correlations with diet
-
Poirier LA, Wise CK, Delongchamp RR, Sinha R. Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet. Cancer Epidemiol. Biomarkers Prev. 10(6), 649-655 (2001). (Pubitemid 32703199)
-
(2001)
Cancer Epidemiology Biomarkers and Prevention
, vol.10
, Issue.6
, pp. 649-655
-
-
Poirier, L.A.1
Wise, C.K.2
Delongchamp, R.R.3
Sinha, R.4
-
118
-
-
0026533906
-
The pathogenesis of homocysteinemia: Interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine
-
Selhub J, Miller JW. The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine. Am. J. Clin. Nutr. 55(1), 131-138 (1992).
-
(1992)
Am. J. Clin. Nutr.
, vol.55
, Issue.1
, pp. 131-138
-
-
Selhub, J.1
Miller, J.W.2
-
119
-
-
84855956247
-
Epigenetics and the environment: Emerging patterns and implications
-
Feil R, Fraga MF. Epigenetics and the environment: emerging patterns and implications. Nat. Publ. Group 13(2), 97-109 (2012).
-
(2012)
Nat. Publ. Group
, vol.13
, Issue.2
, pp. 97-109
-
-
Feil, R.1
Fraga, M.F.2
-
120
-
-
77956335920
-
Exercise effects on methylation of ASC gene
-
Nakajima K, Takeoka M, Mori M et al. Exercise effects on methylation of ASC gene. Int. J. Sports Med. 31(9), 671-675 (2010).
-
(2010)
Int. J. Sports Med.
, vol.31
, Issue.9
, pp. 671-675
-
-
Nakajima, K.1
Takeoka, M.2
Mori, M.3
-
121
-
-
84861138595
-
Age-related increase in levels of 5hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction
-
Chouliaras L, van den Hove DLA, Kenis G et al. Age-related increase in levels of 5hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction. Curr. Alzheimer Res. 9(5), 536-544 (2012).
-
(2012)
Curr. Alzheimer Res.
, vol.9
, Issue.5
, pp. 536-544
-
-
Chouliaras, L.1
Van Den Hove Dla2
Kenis, G.3
-
122
-
-
77952305618
-
Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression
-
Li Y, Liu L, Tollefsbol TO. Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression. FASEB J. 24(5), 1442-1453 (2010).
-
(2010)
FASEB J
, vol.24
, Issue.5
, pp. 1442-1453
-
-
Li, Y.1
Liu, L.2
Tollefsbol, T.O.3
-
123
-
-
0027745794
-
Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro
-
Hass BS, Hart RW, Lu MH, Lyn-Cook BD. Effects of caloric restriction in animals on cellular function, oncogene expression, and DNA methylation in vitro. Mutat. Res. 295(4-6), 281-289 (1993). (Pubitemid 24043521)
-
(1993)
Mutation Research - DNAging Genetic Instability and Aging
, vol.295
, Issue.4-6
, pp. 281-289
-
-
Hass, B.S.1
Hart, R.W.2
Lu, M.H.3
Lyn-Cook, B.D.4
-
124
-
-
79954611176
-
A dual epigenomic approach for the search of obesity biomarkers: DNA methylation in relation to diet-induced weight loss
-
Milagro FI, Campión J, Cordero P et al. A dual epigenomic approach for the search of obesity biomarkers: DNA methylation in relation to diet-induced weight loss. FASEB J. 25(4), 1378-1389 (2011).
-
(2011)
FASEB J.
, vol.25
, Issue.4
, pp. 1378-1389
-
-
Milagro, F.I.1
Campión, J.2
Cordero, P.3
-
125
-
-
67650466971
-
TNFa promoter methylation as a predictive biomarker for weight-loss response
-
Campión J, Milagro FI, Goyenechea E, Martínez JA. TNFa promoter methylation as a predictive biomarker for weight-loss response. Obesity (Silver Spring) 17(6), 1293-1297 (2009).
-
(2009)
Obesity (Silver Spring)
, vol.17
, Issue.6
, pp. 1293-1297
-
-
Campión, J.1
Milagro, F.I.2
Goyenechea, E.3
Martínez, J.A.4
-
126
-
-
66049160126
-
The ageing epigenome: Damaged beyond repair?
-
Sinclair DA, Oberdoerffer P. The ageing epigenome: damaged beyond repair? Ageing Res. Rev. 8(3), 189-198 (2009).
-
(2009)
Ageing Res. Rev.
, vol.8
, Issue.3
, pp. 189-198
-
-
Sinclair, D.A.1
Oberdoerffer, P.2
-
127
-
-
84869159983
-
Stress-associated H3K4 methylation accumulates during postnatal development and aging of Rhesus macaque brain
-
Han Y, Han D, Yan Z et al. Stress-associated H3K4 methylation accumulates during postnatal development and aging of Rhesus macaque brain. Aging Cell 11(6), 1055-1064 (2012).
-
(2012)
Aging Cell
, vol.11
, Issue.6
, pp. 1055-1064
-
-
Han, Y.1
Han, D.2
Yan, Z.3
-
128
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 461(7267), 1071-1078 (2009).
-
(2009)
Nature
, vol.461
, Issue.7267
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
129
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
DOI 10.1126/science.1065521
-
Cortez D, Guntuku S, Qin J, Elledge SJ. ATR and ATRIP: partners in checkpoint signaling. Science 294(5547), 1713-1716 (2001). (Pubitemid 33104841)
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
130
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
DOI 10.1093/emboj/cdg541
-
Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 22(20), 5612-5621 (2003). (Pubitemid 37279970)
-
(2003)
EMBO Journal
, vol.22
, Issue.20
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
131
-
-
15844394846
-
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
-
DOI 10.1038/nature03442
-
Falck J, Coates J, Jackson SP. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 434(7033), 605-611 (2005). (Pubitemid 40488547)
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
132
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276(45), 42462-42467 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.45
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
133
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
DOI 10.1158/0008-5472.CAN-03-3207
-
Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Lobrich M, Jeggo PA. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 64(7), 2390-2396 (2004). (Pubitemid 38523891)
-
(2004)
Cancer Research
, vol.64
, Issue.7
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
134
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
-
Polo SE, Jackson SP. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev. 25(5), 409-433 (2011).
-
(2011)
Genes Dev
, vol.25
, Issue.5
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
135
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146(5), 905-916 (1999).
-
(1999)
J. Cell Biol.
, vol.146
, Issue.5
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
136
-
-
42249102663
-
GH2AX foci form preferentially in euchromatin after ionising-radiation
-
Cowell IG, Sunter NJ, Singh PB, Austin CA, Durkacz BW, Tilby MJ. gH2AX foci form preferentially in euchromatin after ionising-radiation. PLoS ONE 2(10), e1057 (2007).
-
(2007)
PLoS ONE
, vol.2
, Issue.10
-
-
Cowell, I.G.1
Sunter, N.J.2
Singh, P.B.3
Austin, C.A.4
Durkacz, B.W.5
Tilby, M.J.6
-
137
-
-
1642602686
-
Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
-
DOI 10.1038/ncb1095
-
Sedelnikova OA, Horikawa I, Zimonjic DB, Popescu NC, Bonner WM, Barrett JC. Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks. Nat. Cell Biol. 6(2), 168-170 (2004). (Pubitemid 38425717)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.2
, pp. 168-170
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Zimonjic, D.B.3
Popescu, N.C.4
Bonner, W.M.5
Barrett, J.C.6
-
138
-
-
38349134829
-
Delayed kinetics of DNA double-strand break processing in normal and pathological aging
-
Sedelnikova OA, Horikawa I, Redon C et al. Delayed kinetics of DNA double-strand break processing in normal and pathological aging. Aging Cell 7(1), 89-100 (2008).
-
(2008)
Aging Cell
, vol.7
, Issue.1
, pp. 89-100
-
-
Sedelnikova, O.A.1
Horikawa, I.2
Redon, C.3
-
139
-
-
40849106789
-
Histone ubiquitination: Triggering gene activity
-
DOI 10.1016/j.molcel.2008.02.014, PII S1097276508001330
-
Weake VM, Workman JL. Histone ubiquitination: triggering gene activity. Mol. Cell 29(6), 653-663 (2008). (Pubitemid 351400924)
-
(2008)
Molecular Cell
, vol.29
, Issue.6
, pp. 653-663
-
-
Weake, V.M.1
Workman, J.L.2
-
140
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag NM, Rafalska-Metcalf IU, Balane- Bolivar C, Janicki SM, Greenberg RA. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 141(6), 970-981 (2010).
-
(2010)
Cell
, vol.141
, Issue.6
, pp. 970-981
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
141
-
-
80052779612
-
RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response
-
Shiloh Y, Shema E, Moyal L, Oren M. RNF20-RNF40: a ubiquitin-driven link between gene expression and the DNA damage response. FEBS Lett. 585(18), 2795-2802 (2011).
-
(2011)
FEBS Lett
, vol.585
, Issue.18
, pp. 2795-2802
-
-
Shiloh, Y.1
Shema, E.2
Moyal, L.3
Oren, M.4
-
142
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
DOI 10.1038/nature03114
-
Huyen Y, Zgheib O, Ditullio RAJ et al. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 432(7015), 406-411 (2004). (Pubitemid 39551676)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
DiTullio Jr., R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
143
-
-
33845666681
-
Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
-
DOI 10.1016/j.cell.2006.10.043, PII S009286740601525X
-
Botuyan MV, Lee J, Ward IM et al. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127(7), 1361-1373 (2006). (Pubitemid 44960409)
-
(2006)
Cell
, vol.127
, Issue.7
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.-E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
144
-
-
33847247383
-
Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain
-
DOI 10.1002/yea.1441
-
Grenon M, Costelloe T, Jimeno S et al. Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain. Yeast 24(2), 105-119 (2007). (Pubitemid 46322382)
-
(2007)
Yeast
, vol.24
, Issue.2
, pp. 105-119
-
-
Grenon, M.1
Costelloe, T.2
Jimeno, S.3
O'Shaughnessy, A.4
FitzGerald, J.5
Zgheib, O.6
Degerth, L.7
Lowndes, N.F.8
-
145
-
-
57749086992
-
Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage
-
Greeson NT, Sengupta R, Arida AR, Jenuwein T, Sanders SL. Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage. J. Biol. Chem. 283(48), 33168-33174 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.48
, pp. 33168-33174
-
-
Greeson, N.T.1
Sengupta, R.2
Arida, A.R.3
Jenuwein, T.4
Sanders, S.L.5
-
146
-
-
78149423004
-
Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage
-
Oda H, Hubner MR, Beck DB et al. Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage. Mol. Cell 40(3), 364-376 (2010).
-
(2010)
Mol. Cell
, vol.40
, Issue.3
, pp. 364-376
-
-
Oda, H.1
Hubner, M.R.2
Beck, D.B.3
-
147
-
-
77957814604
-
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
-
O'Sullivan RJ, Kubicek S, Schreiber SL, Karlseder J. Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres. Nat. Struct. Mol. Biol. 17(10), 1218-1225 (2010).
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, Issue.10
, pp. 1218-1225
-
-
O'Sullivan, R.J.1
Kubicek, S.2
Schreiber, S.L.3
Karlseder, J.4
-
148
-
-
79551665780
-
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
-
Pei H, Zhang L, Luo K et al. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature 470(7332), 124-128 (2011).
-
(2011)
Nature
, vol.470
, Issue.7332
, pp. 124-128
-
-
Pei, H.1
Zhang, L.2
Luo, K.3
-
149
-
-
30344444484
-
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
-
DOI 10.1038/ncb1343, PII N1343
-
Murr R, Loizou JI, Yang YG et al. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat. Cell Biol. 8(1), 91-99 (2006). (Pubitemid 43064802)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.1
, pp. 91-99
-
-
Murr, R.1
Loizou, J.I.2
Yang, Y.-G.3
Cuenin, C.4
Li, H.5
Wang, Z.-Q.6
Herceg, Z.7
-
150
-
-
78649718101
-
Essential functions of the histone demethylase lid
-
Li L, Greer C, Eisenman RN, Secombe J. Essential functions of the histone demethylase lid. PLoS Genet. 6(11), e1001221 (2010).
-
(2010)
PLoS Genet
, vol.6
, Issue.11
-
-
Li, L.1
Greer, C.2
Eisenman, R.N.3
Secombe, J.4
-
151
-
-
77954360144
-
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair
-
Sharma GG, So S, Gupta A et al. MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol. Cell Biol. 30(14), 3582-3595 (2010).
-
(2010)
Mol. Cell Biol.
, vol.30
, Issue.14
, pp. 3582-3595
-
-
Sharma, G.G.1
So, S.2
Gupta, A.3
-
152
-
-
0023140617
-
Changes in chromatin structure during aging of human skin fibroblasts
-
DOI 10.1016/0014-4827(87)90206-0
-
Ishimi Y, Kojima M, Takeuchi F, Miyamoto T, Yamada M, Hanaoka F. Changes in chromatin structure during aging of human skin fibroblasts. Exp. Cell Res. 169(2), 458-467 (1987). (Pubitemid 17056611)
-
(1987)
Experimental Cell Research
, vol.169
, Issue.2
, pp. 458-467
-
-
Ishimi, Y.1
Kojima, M.2
Takeuchi, F.3
-
153
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
DOI 10.1016/j.molcel.2004.08.031, PII S1097276504005180
-
Vaquero A, Scher M, Lee D, Erdjument- Bromage H, Tempst P, Reinberg D. Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol. Cell 16(1), 93-105 (2004). (Pubitemid 39330155)
-
(2004)
Molecular Cell
, vol.16
, Issue.1
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
154
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, Michan S, McVay M et al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 135(5), 907-918 (2008).
-
(2008)
Cell
, vol.135
, Issue.5
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
-
155
-
-
0033612287
-
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
-
DOI 10.1016/S0092-8674(00)80773-4
-
Martin SG, Laroche T, Suka N, Grunstein M, Gasser S M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97, 621-633 (1999). (Pubitemid 29256965)
-
(1999)
Cell
, vol.97
, Issue.5
, pp. 621-633
-
-
Martin, S.G.1
Laroche, T.2
Suka, N.3
Grunstein, M.4
Gasser, S.M.5
-
156
-
-
36248954501
-
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
-
DOI 10.1038/nature06268, PII NATURE06268
-
Vaquero A, Scher M, Erdjument-Bromage H, Tempst P, Serrano L, Reinberg D. SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature 450(7168), 440-444 (2007). (Pubitemid 350126745)
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 440-444
-
-
Vaquero, A.1
Scher, M.2
Erdjument-Bromage, H.3
Tempst, P.4
Serrano, L.5
Reinberg, D.6
-
157
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
DOI 10.1016/j.cell.2005.11.044, PII S0092867406000493
-
Mostoslavsky R, Chua KF, Lombard DB et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124(2), 315-329 (2006). (Pubitemid 43121980)
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.-L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yancopoulos, G.D.30
Alt, F.W.31
more..
-
158
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
DOI 10.1038/nature06736, PII NATURE06736
-
Michishita E, McCord RA, Berber E et al. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452(7186), 492-496 (2008). (Pubitemid 351450840)
-
(2008)
Nature
, vol.452
, Issue.7186
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.A.9
Barrett, J.C.10
Chang, H.Y.11
Bohr, V.A.12
Ried, T.13
Gozani, O.14
Chua, K.F.15
-
159
-
-
69249221533
-
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
-
Michishita E, McCord RA, Boxer LD et al. Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6. Cell Cycle 8(16), 2664-2666 (2009).
-
(2009)
Cell Cycle
, vol.8
, Issue.16
, pp. 2664-2666
-
-
Michishita, E.1
McCord, R.A.2
Boxer, L.D.3
-
160
-
-
79959846078
-
Dynamic chromatin localization of Sirt6 shapes stress-and aging-related transcriptional networks
-
Kawahara TL, Rapicavoli NA, Wu AR, Qu K, Quake SR, Chang HY. Dynamic chromatin localization of Sirt6 shapes stress-and aging-related transcriptional networks. PLoS Genet. 7(6), e1002153 (2011).
-
(2011)
PLoS Genet
, vol.7
, Issue.6
-
-
Kawahara, T.L.1
Rapicavoli, N.A.2
Wu, A.R.3
Qu, K.4
Quake, S.R.5
Chang, H.Y.6
-
161
-
-
32444434989
-
Histone H4-K16 acetylation controls chromatin structure and protein interactions
-
DOI 10.1126/science.1124000
-
Shogren-Knaak M, Ishii H, Sun JM, Pazin MJ, Davie JR, Peterson CL. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 311(5762), 844-847 (2006). (Pubitemid 43228847)
-
(2006)
Science
, vol.311
, Issue.5762
, pp. 844-847
-
-
Shogren-Knaak, M.1
Ishii, H.2
Sun, J.-M.3
Pazin, M.J.4
Davie, J.R.5
Peterson, C.L.6
-
162
-
-
67149099680
-
Histone H4 lysine 16 acetylation regulates cellular lifespan
-
Dang W, Steffen KK, Perry R et al. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459(7248), 802-807 (2009).
-
(2009)
Nature
, vol.459
, Issue.7248
, pp. 802-807
-
-
Dang, W.1
Steffen, K.K.2
Perry, R.3
-
163
-
-
33646745137
-
Lamin A-dependent nuclear defects in human aging
-
Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science 312(5776), 1059-1063 (2006).
-
(2006)
Science
, vol.312
, Issue.5776
, pp. 1059-1063
-
-
Scaffidi, P.1
Misteli, T.2
-
164
-
-
33745016642
-
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
-
DOI 10.1073/pnas.0602569103
-
Shumaker DK, Dechat T, Kohlmaier A et al. Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc. Natl Acad. Sci. USA 103(23), 8703-8708 (2006). (Pubitemid 43878083)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.23
, pp. 8703-8708
-
-
Shumaker, D.K.1
Dechat, T.2
Kohlmaier, A.3
Adam, S.A.4
Bozovsky, M.R.5
Erdos, M.R.6
Eriksson, M.7
Goldman, A.E.8
Khuon, S.9
Collins, F.S.10
Jenuwein, T.11
Goldman, R.D.12
-
165
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
DOI 10.1016/S0092-8674(03)00401-X
-
Narita M, Nunez S, Heard E et al. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113(6), 703-716 (2003). (Pubitemid 36724935)
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
166
-
-
19944427674
-
Formation of macroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
-
DOI 10.1016/j.devcel.2004.10.019, PII S1534580704004083
-
Zhang R, Poustovoitov MV, Ye X et al. Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev. Cell 8(1), 19-30 (2005). (Pubitemid 40058002)
-
(2005)
Developmental Cell
, vol.8
, Issue.1
, pp. 19-30
-
-
Zhang, R.1
Poustovoitov, M.V.2
Ye, X.3
Santos, H.A.4
Chen, W.5
Daganzo, S.M.6
Erzberger, J.P.7
Serebriiskii, I.G.8
Canutescu, A.A.9
Dunbrack, R.L.10
Pehrson, J.R.11
Berger, J.M.12
Kaufman, P.D.13
Adams, P.D.14
-
167
-
-
84861868041
-
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
-
Chicas A, Kapoor A, Wang X et al. H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proc. Natl Acad. Sci. USA 109(23), 8971-8976 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, Issue.23
, pp. 8971-8976
-
-
Chicas, A.1
Kapoor, A.2
Wang, X.3
-
168
-
-
33644692330
-
Cellular senescence in aging primates
-
DOI 10.1126/science.1122446
-
Herbig U, Ferreira M, Condel L, Carey D, Sedivy JM. Cellular senescence in aging primates. Science 311(5765), 1257 (2006). (Pubitemid 43334708)
-
(2006)
Science
, vol.311
, Issue.5765
, pp. 1257
-
-
Herbig, U.1
Ferreira, M.2
Condel, L.3
Carey, D.4
Sedivy, J.M.5
-
169
-
-
12544259900
-
DNA methyltransferase gene dDnmt2 and longevity of Drosophila
-
Lin MJ, Tang LY, Reddy MN, Shen CK. DNA methyltransferase gene dDnmt2 and longevity of Drosophila. J. Biol. Chem. 280(2), 861-864 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, Issue.2
, pp. 861-864
-
-
Lin, M.J.1
Tang, L.Y.2
Reddy, M.N.3
Shen, C.K.4
-
170
-
-
31144449613
-
Asp by the DNA methyltransferase homolog Dnmt2
-
DOI 10.1126/science.1120976
-
Goll MG, Kirpekar F, Maggert KA et al. Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science 311(5759), 395-398 (2006). (Pubitemid 43132667)
-
(2006)
Science
, vol.311
, Issue.5759
, pp. 395-398
-
-
Goll, M.G.1
Kirpekar, F.2
Maggert, K.A.3
Yoder, J.A.4
Hsieh, C.-L.5
Zhang, X.6
Golic, K.G.7
Jacobsen, S.E.8
Bestor, T.H.9
-
171
-
-
84860572791
-
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
-
Bell JT, Tsai PC, Yang TP et al. Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet. 8(4), e1002629 (2012).
-
(2012)
PLoS Genet
, vol.8
, Issue.4
-
-
Bell, J.T.1
Tsai, P.C.2
Yang, T.P.3
-
172
-
-
84855979661
-
Whole genome sequences of a male and female supercentenarian, ages greater than 114 years
-
Sebastiani P, Riva A, Montano M et al. Whole genome sequences of a male and female supercentenarian, ages greater than 114 years. Front. Genet. 2, 90 (2011).
-
(2011)
Front. Genet.
, vol.2
, pp. 90
-
-
Sebastiani, P.1
Riva, A.2
Montano, M.3
-
173
-
-
80053529549
-
Analysis of alternative splicing associated with aging and neurodegeneration in the human brain
-
Tollervey JR, Wang Z, Hortobágyi T et al. Analysis of alternative splicing associated with aging and neurodegeneration in the human brain. Genome Res. 21(10), 1572-1582 (2011).
-
(2011)
Genome Res
, vol.21
, Issue.10
, pp. 1572-1582
-
-
Tollervey, J.R.1
Wang, Z.2
Hortobágyi, T.3
-
174
-
-
0033214237
-
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
-
DOI 10.1101/gad.13.19.2570
-
Kaeberlein M, McVey M, Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13(19), 2570-2580 (1999). (Pubitemid 29489648)
-
(1999)
Genes and Development
, vol.13
, Issue.19
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
175
-
-
80053134340
-
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
-
Viswanathan M, Guarente L. Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes. Nature 477(7365), E1-E2 (2011).
-
(2011)
Nature
, vol.477
, Issue.7365
-
-
Viswanathan, M.1
Guarente, L.2
-
176
-
-
48349144852
-
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
-
Pearson KJ, Baur JA, Lewis KN et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 8(2), 157-168 (2008).
-
(2008)
Cell Metab
, vol.8
, Issue.2
, pp. 157-168
-
-
Pearson, K.J.1
Baur, J.A.2
Lewis, K.N.3
-
177
-
-
77952168294
-
Altered histone acetylation is associated with age-dependent memory impairment in mice
-
Peleg S, Sananbenesi F, Zovoilis A et al. Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 328(5979), 753-756 (2010).
-
(2010)
Science
, vol.328
, Issue.5979
, pp. 753-756
-
-
Peleg, S.1
Sananbenesi, F.2
Zovoilis, A.3
-
178
-
-
77954660029
-
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
-
Greer EL, Maures TJ, Hauswirth AG et al. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature 466(7304), 383-387 (2010).
-
(2010)
Nature
, vol.466
, Issue.7304
, pp. 383-387
-
-
Greer, E.L.1
Maures, T.J.2
Hauswirth, A.G.3
-
179
-
-
79960936857
-
Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway
-
Jin C, Li J, Green CD et al. Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. Cell Metab. 14(2), 161-172 (2011).
-
(2011)
Cell Metab
, vol.14
, Issue.2
, pp. 161-172
-
-
Jin, C.1
Li, J.2
Green, C.D.3
-
180
-
-
81155139577
-
The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner
-
Maures TJ, Greer EL, Hauswirth AG, Brunet A. The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner. Aging Cell 10(6), 980-990 (2011).
-
(2011)
Aging Cell
, vol.10
, Issue.6
, pp. 980-990
-
-
Maures, T.J.1
Greer, E.L.2
Hauswirth, A.G.3
Brunet, A.4
-
181
-
-
47849124269
-
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
-
Cogswell JP, Ward J, Taylor IA et al. Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J. Alzheimers Dis. 14(1), 27-41 (2008). (Pubitemid 352039013)
-
(2008)
Journal of Alzheimer's Disease
, vol.14
, Issue.1
, pp. 27-41
-
-
Cogswell, J.P.1
Ward, J.2
Taylor, I.A.3
Waters, M.4
Shi, Y.5
Cannon, B.6
Kelnar, K.7
Kemppainen, J.8
Brown, D.9
Chen, C.10
Prinjha, R.K.11
Richardson, J.C.12
Saunders, A.M.13
Roses, A.D.14
Richards, C.A.15
-
182
-
-
84869853276
-
Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans
-
Lehrbach NJ, Castro C, Murfitt KJ, Abreu- Goodger C, Griffin JL, Miska EA. Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans. RNA 18(12), 2220-2235 (2012).
-
(2012)
RNA
, vol.18
, Issue.12
, pp. 2220-2235
-
-
Lehrbach, N.J.1
Castro, C.2
Murfitt, K.J.3
Abreu- Goodger, C.4
Griffin, J.L.5
Miska, E.A.6
-
183
-
-
80053210307
-
Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans
-
Kato M, Chen X, Inukai S, Zhao H, Slack FJ. Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans. RNA 17(10), 1804-1820 (2011).
-
(2011)
RNA
, vol.17
, Issue.10
, pp. 1804-1820
-
-
Kato, M.1
Chen, X.2
Inukai, S.3
Zhao, H.4
Slack, F.J.5
-
184
-
-
78650490230
-
MicroRNAs both promote and antagonize longevity in C
-
de Lencastre A, Pincus Z, Zhou K, Kato M, Lee SS, Slack FJ. MicroRNAs both promote and antagonize longevity in C. elegans. Curr. Biol. 20(24), 2159-2168 (2010).
-
(2010)
Elegans. Curr. Biol.
, vol.20
, Issue.24
, pp. 2159-2168
-
-
De Lencastre, A.1
Pincus, Z.2
Zhou, K.3
Kato, M.4
Lee, S.S.5
Slack, F.J.6
-
185
-
-
80053446656
-
MicroRNA Predictors of longevity in Caenorhabditis elegans
-
Pincus Z, Smith-Vikos T, Slack FJ. MicroRNA Predictors of longevity in Caenorhabditis elegans. PLoS Genet. 7(9), e1002306 (2011).
-
(2011)
PLoS Genet
, vol.7
, Issue.9
-
-
Pincus, Z.1
Smith-Vikos, T.2
Slack, F.J.3
-
186
-
-
29344467120
-
Physiology: A developmental timing microRNA and its target regulate life span in C. elegans
-
DOI 10.1126/science.1115596
-
Boehm M, Slack F. A developmental timing microRNA and its target regulate life span in C. elegans. Science 310(5756), 1954-1957 (2005). (Pubitemid 43005988)
-
(2005)
Science
, vol.310
, Issue.5756
, pp. 1954-1957
-
-
Boehm, M.1
Slack, F.2
-
187
-
-
84864026078
-
Genome-wide miRNA signatures of human longevity
-
Elsharawy A, Keller A, Flachsbart F et al. Genome-wide miRNA signatures of human longevity. Aging Cell 11(4), 607-616 (2012).
-
(2012)
Aging Cell
, vol.11
, Issue.4
, pp. 607-616
-
-
Elsharawy, A.1
Keller, A.2
Flachsbart, F.3
-
188
-
-
77956513434
-
MicroRNA expression patterns reveal differential expression of target genes with age
-
Noren Hooten N, Abdelmohsen K, Gorospe M, Ejiogu N, Zonderman AB, Evans MK. microRNA expression patterns reveal differential expression of target genes with age. PLoS ONE 5(5), e10724 (2010).
-
(2010)
PLoS ONE
, vol.5
, Issue.5
-
-
Noren Hooten, N.1
Abdelmohsen, K.2
Gorospe, M.3
Ejiogu, N.4
Zonderman, A.B.5
Evans, M.K.6
-
189
-
-
84864206603
-
Novel microRNAs differentially expressed during aging in the mouse brain
-
Inukai S, de Lencastre A, Turner M, Slack F. Novel microRNAs differentially expressed during aging in the mouse brain. PLoS ONE 7(7), e40028 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.7
-
-
Inukai, S.1
De Lencastre, A.2
Turner, M.3
Slack, F.4
-
190
-
-
80053648859
-
Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis
-
Persengiev S, Kondova I, Otting N, Koeppen AH, Bontrop RE. Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis. Neurobiol. Aging 32(12), 2316.e17-2316.e27 (2011).
-
(2011)
Neurobiol. Aging
, vol.32
, Issue.12
-
-
Persengiev, S.1
Kondova, I.2
Otting, N.3
Koeppen, A.H.4
Bontrop, R.E.5
-
191
-
-
80855165230
-
Circulatory miR34a as an RNAbased, noninvasive biomarker for brain aging
-
Li X, Khanna A, Li N, Wang E. Circulatory miR34a as an RNAbased, noninvasive biomarker for brain aging. Aging (Albany NY). 3(10), 985-1002 (2011).
-
(2011)
Aging (Albany NY)
, vol.3
, Issue.10
, pp. 985-1002
-
-
Li, X.1
Khanna, A.2
Li, N.3
Wang, E.4
-
192
-
-
84859466185
-
The C. elegans microRNA mir-71 acts in neurons to promote germline-mediated longevity through regulation of DAF-16/FOXO
-
Boulias K, Horvitz HR. The C. elegans microRNA mir-71 acts in neurons to promote germline-mediated longevity through regulation of DAF-16/FOXO. Cell Metab. 15(4), 439-450 (2012).
-
(2012)
Cell Metab
, vol.15
, Issue.4
, pp. 439-450
-
-
Boulias, K.1
Horvitz, H.R.2
-
193
-
-
77649337904
-
MicroRNA group disorganization in aging
-
Lanceta J, Prough RA, Liang R, Wang E. MicroRNA group disorganization in aging. Exp. Gerontol. 45(4), 269-278 (2010).
-
(2010)
Exp. Gerontol.
, vol.45
, Issue.4
, pp. 269-278
-
-
Lanceta, J.1
Prough, R.A.2
Liang, R.3
Wang, E.4
-
194
-
-
83255184978
-
Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans
-
Rechavi O, Minevich G, Hobert O. Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans. Cell 147(6), 1248-1256 (2011).
-
(2011)
Cell
, vol.147
, Issue.6
, pp. 1248-1256
-
-
Rechavi, O.1
Minevich, G.2
Hobert, O.3
-
195
-
-
83755183247
-
Nuclear RNAi maintains heritable gene silencing in Caenorhabditis elegans
-
Burton NO, Burkhart KB, Kennedy S. Nuclear RNAi maintains heritable gene silencing in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 108(49), 19683-19688 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.49
, pp. 19683-19688
-
-
Burton, N.O.1
Burkhart, K.B.2
Kennedy, S.3
-
196
-
-
57149104113
-
An epigenetic role for maternally inherited piRNAs in transposon silencing
-
DOI 10.1126/science.1165171
-
Brennecke J, Malone CD, Aravin AA, Sachidanandam R, Stark A, Hannon GJ. An epigenetic role for maternally inherited piRNAs in transposon silencing. Science 322(5906), 1387-1392 (2008). (Pubitemid 352775252)
-
(2008)
Science
, vol.322
, Issue.5906
, pp. 1387-1392
-
-
Brennecke, J.1
Malone, C.D.2
Aravin, A.A.3
Sachidanandam, R.4
Stark, A.5
Hannon, G.J.6
-
197
-
-
84863628945
-
PiRNA-mediated transgenerational inheritance of an acquired trait
-
Grentzinger T, Armenise C, Brun C et al. piRNA-mediated transgenerational inheritance of an acquired trait. Genome Res. 22(10), 1877-1888 (2012).
-
(2012)
Genome Res
, vol.22
, Issue.10
, pp. 1877-1888
-
-
Grentzinger, T.1
Armenise, C.2
Brun, C.3
-
198
-
-
52049098967
-
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
-
Aravin AA, Sachidanandam R, Bourc'his D et al. A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol. Cell 31(6), 785-799 (2008).
-
(2008)
Mol. Cell
, vol.31
, Issue.6
, pp. 785-799
-
-
Aravin, A.A.1
Sachidanandam, R.2
Bourc'His, D.3
-
199
-
-
77952581350
-
Long non-coding RNAs in nervous system function and disease
-
Qureshi IA, Mattick JS, Mehler MF. Long non-coding RNAs in nervous system function and disease. Brain Res. 1338, 20-35 (2010).
-
(2010)
Brain Res
, vol.1338
, pp. 20-35
-
-
Qureshi, I.A.1
Mattick, J.S.2
Mehler, M.F.3
-
200
-
-
84880569773
-
Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome
-
doi:10.1007/s11357-012-9410-91 Epub ahead of print
-
Wood SH, Craig T, Li Y, Merry B, de Magalhaes JP. Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome. Age (Dordr.) doi:10.1007/ s11357-012-9410-1 (2012) (Epub ahead of print).
-
(2012)
Age (Dordr.)
-
-
Wood, S.H.1
Craig, T.2
Li, Y.3
Merry, B.4
De Magalhaes, J.P.5
-
201
-
-
78049436255
-
Longevity is not influenced by prenatal programming of body size
-
Conover CA, Bale LK, Grell JA, Mader JR, Mason MA. Longevity is not influenced by prenatal programming of body size. Aging Cell 9(4), 647-649 (2010).
-
(2010)
Aging Cell
, vol.9
, Issue.4
, pp. 647-649
-
-
Conover, C.A.1
Bale, L.K.2
Grell, J.A.3
Mader, J.R.4
Mason, M.A.5
-
202
-
-
33645324024
-
RNA-mediated response to heat shock in mammalian cells
-
Shamovsky I, Ivannikov M, Kandel ES, Gershon D, Nudler E. RNA-mediated response to heat shock in mammalian cells. Nature 440(7083), 556-560 (2006).
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 556-560
-
-
Shamovsky, I.1
Ivannikov, M.2
Kandel, E.S.3
Gershon, D.4
Nudler, E.5
-
203
-
-
84861783529
-
LncRNA profile of glioblastoma reveals the potential role of lncRNAs in contributing to glioblastoma pathogenesis
-
Han L, Zhang K, Shi Z et al. LncRNA profile of glioblastoma reveals the potential role of lncRNAs in contributing to glioblastoma pathogenesis. Int. J. Oncol. 40(6), 2004-2012 (2012).
-
(2012)
Int. J. Oncol.
, vol.40
, Issue.6
, pp. 2004-2012
-
-
Han, L.1
Zhang, K.2
Shi, Z.3
-
204
-
-
83255188897
-
Polycomb-repressed genes have permissive enhancers that initiate reprogramming
-
Taberlay PC, Kelly TK, Liu CC et al. Polycomb-repressed genes have permissive enhancers that initiate reprogramming. Cell 147(6), 1283-1294 (2011).
-
(2011)
Cell
, vol.147
, Issue.6
, pp. 1283-1294
-
-
Taberlay, P.C.1
Kelly, T.K.2
Liu, C.C.3
-
205
-
-
70349322609
-
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA
-
Jeong S, Liang G, Sharma S et al. Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol. Cell Biol. 29(19), 5366-5376 (2009).
-
(2009)
Mol. Cell Biol.
, vol.29
, Issue.19
, pp. 5366-5376
-
-
Jeong, S.1
Liang, G.2
Sharma, S.3
-
206
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
DOI 10.1038/nature05987, PII NATURE05987
-
Ooi SK, Qiu C, Bernstein E et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448(7154), 714-717 (2007). (Pubitemid 47236857)
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 714-717
-
-
Ooi, S.K.T.1
Qiu, C.2
Bernstein, E.3
Li, K.4
Jia, D.5
Yang, Z.6
Erdjument-Bromage, H.7
Tempst, P.8
Lin, S.-P.9
Allis, C.D.10
Cheng, X.11
Bestor, T.H.12
-
207
-
-
59649127791
-
UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells
-
Kim JK, Estève PO, Jacobsen SE, Pradhan S. UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells. Nucleic Acids Res. 37(2), 493-505 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, Issue.2
, pp. 493-505
-
-
Kim, J.K.1
Estève, P.O.2
Jacobsen, S.E.3
Pradhan, S.4
-
208
-
-
83255186739
-
SIRT1 Deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities
-
Peng L, Yuan Z, Ling H et al. SIRT1 Deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Mol. Cell Biol. 31(23), 4720-4734 (2011).
-
(2011)
Mol. Cell Biol.
, vol.31
, Issue.23
, pp. 4720-4734
-
-
Peng, L.1
Yuan, Z.2
Ling, H.3
-
209
-
-
77956931047
-
H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes
-
Kelly TK, Miranda TB, Liang G et al. H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes. Mol. Cell 39(6), 901-911 (2010).
-
(2010)
Mol. Cell
, vol.39
, Issue.6
, pp. 901-911
-
-
Kelly, T.K.1
Miranda, T.B.2
Liang, G.3
-
210
-
-
67549119096
-
CTCF: Master weaver of the genome
-
Phillips JE, Corces VG. CTCF: master weaver of the genome. Cell 137(7), 1194-1211 (2009).
-
(2009)
Cell
, vol.137
, Issue.7
, pp. 1194-1211
-
-
Phillips, J.E.1
Corces, V.G.2
-
211
-
-
80455176999
-
CTCFpromoted RNA polymerase II pausing links DNA methylation to splicing
-
Shukla S, Kavak E, Gregory M et al. CTCFpromoted RNA polymerase II pausing links DNA methylation to splicing. Nature 479(7371), 74-79 (2011).
-
(2011)
Nature
, vol.479
, Issue.7371
, pp. 74-79
-
-
Shukla, S.1
Kavak, E.2
Gregory, M.3
-
212
-
-
84865836579
-
Widespread plasticity in CTCF occupancy linked to DNA methylation
-
Wang H, Maurano MT, Qu H et al. Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Res. 22(9), 1680-1688 (2012).
-
(2012)
Genome Res
, vol.22
, Issue.9
, pp. 1680-1688
-
-
Wang, H.1
Maurano, M.T.2
Qu, H.3
-
213
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
DOI 10.1038/30764
-
Nan X, Ng HH, Johnson CA et al. Transcriptional repression by the methyl- CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393(6683), 386-389 (1998). (Pubitemid 28269714)
-
(1998)
Nature
, vol.393
, Issue.6683
, pp. 386-389
-
-
Nan, X.1
Ng, H.-H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
214
-
-
33645218438
-
A family of human zinc finger proteins that bind methylated DNA and repress transcription
-
Filion GJ, Zhenilo S, Salozhin S, Yamada D, Prokhortchouk E, Defossez PA. A family of human zinc finger proteins that bind methylated DNA and repress transcription. Mol. Cell Biol. 26(1), 169-181 (2006).
-
(2006)
Mol. Cell Biol.
, vol.26
, Issue.1
, pp. 169-181
-
-
Filion, G.J.1
Zhenilo, S.2
Salozhin, S.3
Yamada, D.4
Prokhortchouk, E.5
Defossez, P.A.6
-
215
-
-
80555156105
-
In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions
-
Quenneville S, Verde G, Corsinotti A et al. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions. Mol. Cell 44(3), 361-372 (2011).
-
(2011)
Mol. Cell
, vol.44
, Issue.3
, pp. 361-372
-
-
Quenneville, S.1
Verde, G.2
Corsinotti, A.3
-
216
-
-
0023657424
-
Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation
-
Lock LF, Takagi N, Martin GR. Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation. Cell 48(1), 39-46 (1987).
-
(1987)
Cell
, vol.48
, Issue.1
, pp. 39-46
-
-
Lock, L.F.1
Takagi, N.2
Martin, G.R.3
-
217
-
-
84555207349
-
Dnmt3a is essential for hematopoietic stem cell differentiation
-
Challen GA, Sun D, Jeong M et al. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat. Genet. 44(1), 23-31 (2012).
-
(2012)
Nat. Genet.
, vol.44
, Issue.1
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
-
218
-
-
51349105905
-
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
-
Gal-Yam EN, Egger G, Iniguez L et al. Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc. Natl Acad. Sci. USA 105(35), 12979-12984 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.35
, pp. 12979-12984
-
-
Gal-Yam, E.N.1
Egger, G.2
Iniguez, L.3
-
219
-
-
33846649587
-
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
-
DOI 10.1038/ng1950, PII NG1950
-
Schlesinger Y, Straussman R, Keshet I et al. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat. Genet. 39(2), 232-236 (2007). (Pubitemid 46184355)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
Farkash, S.4
Hecht, M.5
Zimmerman, J.6
Eden, E.7
Yakhini, Z.8
Ben-Shushan, E.9
Reubinoff, B.E.10
Bergman, Y.11
Simon, I.12
Cedar, H.13
-
220
-
-
33645768490
-
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
-
Pruitt K, Zinn RL, Ohm JE et al. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet. 2(3), e40 (2006).
-
(2006)
PLoS Genet
, vol.2
, Issue.3
-
-
Pruitt, K.1
Zinn, R.L.2
Ohm, J.E.3
-
221
-
-
84857742284
-
DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory
-
Raynal NJ, Si J, Taby RF et al. DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory. Cancer Res. 72(5), 1170-1181 (2012).
-
(2012)
Cancer Res
, vol.72
, Issue.5
, pp. 1170-1181
-
-
Raynal, N.J.1
Si, J.2
Taby, R.F.3
-
222
-
-
10644237968
-
RNAi-mediated pathways in the nucleus
-
DOI 10.1038/nrg1500
-
Matzke MA, Birchler JA. RNAi-mediated pathways in the nucleus. Nat. Rev. Genet. 6(1), 24-35 (2005). (Pubitemid 39657895)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.1
, pp. 24-35
-
-
Matzke, M.A.1
Birchler, J.A.2
-
223
-
-
42149171774
-
Small RNA guides for de novo DNA methylation in mammalian germ cells
-
DOI 10.1101/gad.1669408
-
Aravin AA, Bourc'his D. Small RNA guides for de novo DNA methylation in mammalian germ cells. Genes Dev. 22(8), 970-975 (2008). (Pubitemid 351544235)
-
(2008)
Genes and Development
, vol.22
, Issue.8
, pp. 970-975
-
-
Aravin, A.A.1
Bourc'his, D.2
-
224
-
-
77958576363
-
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes
-
Schmitz KM, Mayer C, Postepska A, Grummt I. Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes. Genes Dev. 24(20), 2264-2269 (2010).
-
(2010)
Genes Dev
, vol.24
, Issue.20
, pp. 2264-2269
-
-
Schmitz, K.M.1
Mayer, C.2
Postepska, A.3
Grummt, I.4
-
225
-
-
82355184502
-
Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation
-
Holz-Schietinger C, Matje DM, Flexer Harrison M, Reich NO. Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation. J. Biol. Chem. 286(48), 41479-41488 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.48
, pp. 41479-41488
-
-
Holz-Schietinger, C.1
Matje, D.M.2
Flexer Harrison, M.3
Reich, N.O.4
-
226
-
-
64349091471
-
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
-
Ball MP, Li JB, Gao Y et al. Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat. Biotechnol. 27(4), 361-368 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, Issue.4
, pp. 361-368
-
-
Ball, M.P.1
Li, J.B.2
Gao, Y.3
-
227
-
-
79961022267
-
Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters
-
Koch F, Fenouil R, Gut M et al. Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Nat. Struct. Mol. Biol. 18(8), 956-963 (2011).
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, Issue.8
, pp. 956-963
-
-
Koch, F.1
Fenouil, R.2
Gut, M.3
-
228
-
-
84860496011
-
Linking the epigenome to the genome: Correlation of different features to DNA methylation of CpG islands
-
Wrzodek C, Büchel F, Hinselmann G, Eichner J, Mittag F, Zell A. Linking the epigenome to the genome: correlation of different features to DNA methylation of CpG islands. PLoS ONE 7(4), e35327 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.4
-
-
Wrzodek, C.1
Büchel, F.2
Hinselmann, G.3
Eichner, J.4
Mittag, F.5
Zell, A.6
-
229
-
-
84861977900
-
Comparative epigenomic annotation of regulatory DNA
-
Xiao S, Xie D, Cao X et al. Comparative epigenomic annotation of regulatory DNA. Cell 149(6), 1381-1392 (2012).
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1381-1392
-
-
Xiao, S.1
Xie, D.2
Cao, X.3
-
230
-
-
84856453032
-
Sensitive and specific single-molecule sequencing of 5 hydroxymethylcytosine
-
Song CX, Clark TA, Lu XY et al. Sensitive and specific single-molecule sequencing of 5?hydroxymethylcytosine. Nat. Methods 9(1), 75-77 (2012).
-
(2012)
Nat. Methods
, vol.9
, Issue.1
, pp. 75-77
-
-
Song, C.X.1
Clark, T.A.2
Lu, X.Y.3
-
231
-
-
84862680856
-
Rewriting the epigenome
-
Carone BR, Rando OJ. Rewriting the epigenome. Cell 149(7), 1422-1423 (2012).
-
(2012)
Cell
, vol.149
, Issue.7
, pp. 1422-1423
-
-
Carone, B.R.1
Rando, O.J.2
-
232
-
-
84868008258
-
The role of DNA methylation in aging, rejuvenation, and age-related disease
-
Johnson AA, Akman K, Calimport SRG, Wuttke D, Stolzing A, de Magalhães JP. The role of DNA methylation in aging, rejuvenation, and age-related disease. Rejuvenation Res. 15(5), 483-494 (2012).
-
(2012)
Rejuvenation Res.
, vol.15
, Issue.5
, pp. 483-494
-
-
Johnson, A.A.1
Akman, K.2
Srg, C.3
Wuttke, D.4
Stolzing, A.5
De Magalhães, J.P.6
-
233
-
-
12244279345
-
Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry
-
DOI 10.1021/ac0489420
-
Song L, James SR, Kazim L, Karpf AR. Specific method for the determination of genomic DNA methylation by liquid chromatography-electrospray ionization tandem mass spectrometry. Anal. Chem. 77(2), 504-510 (2005). (Pubitemid 40116829)
-
(2005)
Analytical Chemistry
, vol.77
, Issue.2
, pp. 504-510
-
-
Song, L.1
James, S.R.2
Kazim, L.3
Karpf, A.R.4
-
234
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
DOI 10.1038/ng1598
-
Weber M, Davies JJ, Wittig D et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat. Genet. 37(8), 853-862 (2005). (Pubitemid 41077111)
-
(2005)
Nature Genetics
, vol.37
, Issue.8
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
Oakeley, E.J.4
Haase, M.5
Lam, W.L.6
Schubeler, D.7
-
235
-
-
84856306090
-
Genomewide DNA methylation profiling using Infinium® assay
-
Bibikova M, Le J, Barnes B et al. Genomewide DNA methylation profiling using Infinium® assay. Epigenomics 1(1), 177-200 (2009).
-
(2009)
Epigenomics
, vol.1
, Issue.1
, pp. 177-200
-
-
Bibikova, M.1
Le Barnes, J.B.2
-
236
-
-
0026546877
-
A genomic sequencing protocol that yields a positive display of 5methylcytosine residues in individual DNA strands
-
Frommer M, McDonald LE, Millar DS et al. A genomic sequencing protocol that yields a positive display of 5methylcytosine residues in individual DNA strands. Proc. Natl Acad. Sci. USA 89(5), 1827-1831 (1992).
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, Issue.5
, pp. 1827-1831
-
-
Frommer, M.1
McDonald, L.E.2
Millar, D.S.3
-
237
-
-
77749277177
-
The behaviour of 5hydroxymethylcytosine in bisulfite sequencing
-
Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A. The behaviour of 5hydroxymethylcytosine in bisulfite sequencing. PLoS ONE 5(1), e8888 (2010).
-
(2010)
PLoS ONE
, vol.5
, Issue.1
-
-
Huang, Y.1
Pastor, W.A.2
Shen, Y.3
Tahiliani, M.4
Liu, D.R.5
Rao, A.6
-
238
-
-
79952788617
-
Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling
-
Gu H, Smith ZD, Bock C, Boyle P, Gnirke A, Meissner A. Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling. Nat. Protocols 6(4), 468-481 (2011).
-
(2011)
Nat. Protocols
, vol.6
, Issue.4
, pp. 468-481
-
-
Gu, H.1
Smith, Z.D.2
Bock, C.3
Boyle, P.4
Gnirke, A.5
Meissner, A.6
-
239
-
-
77954224132
-
Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns
-
Edwards JR, O'Donnell AH, Rollins RA et al. Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns. Genome Res. 20(7), 972-980 (2010).
-
(2010)
Genome Res.
, vol.20
, Issue.7
, pp. 972-980
-
-
Edwards, J.R.1
O'Donnell, A.H.2
Rollins, R.A.3
-
240
-
-
46949098742
-
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
-
DOI 10.1038/nbt1414, PII NBT1414
-
Down TA, Rakyan VK, Turner DJ et al. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nat. Biotechnol. 26(7), 779-785 (2008). (Pubitemid 351961453)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.7
, pp. 779-785
-
-
Down, T.A.1
Rakyan, V.K.2
Turner, D.J.3
Flicek, P.4
Li, H.5
Kulesha, E.6
Graf, S.7
Johnson, N.8
Herrero, J.9
Tomazou, E.M.10
Thorne, N.P.11
Backdahl, L.12
Herberth, M.13
Howe, K.L.14
Jackson, D.K.15
Miretti, M.M.16
Marioni, J.C.17
Birney, E.18
Hubbard, T.J.P.19
Durbin, R.20
Tavare, S.21
Beck, S.22
more..
-
241
-
-
70449450290
-
One-pot shotgun quantitative mass spectrometry characterization of histones
-
Plazas-Mayorca MD, Zee BM, Young NL et al. One-pot shotgun quantitative mass spectrometry characterization of histones. J. Proteome Res. 8(11), 5367-5374 (2009).
-
(2009)
J. Proteome Res.
, vol.8
, Issue.11
, pp. 5367-5374
-
-
Plazas-Mayorca, M.D.1
Zee, B.M.2
Young, N.L.3
-
242
-
-
0037172993
-
Methylation of histone H3 Lys 4 in coding regions of active genes
-
DOI 10.1073/pnas.082249499
-
Bernstein BE, Humphrey EL, Erlich RL et al. Methylation of histone H3 Lys 4 in coding regions of active genes. Proc. Natl Acad. Sci. USA 99(13), 8695-8700 (2002). (Pubitemid 34693622)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8695-8700
-
-
Bernstein, B.E.1
Humphrey, E.L.2
Erlich, R.L.3
Schneider, R.4
Bouman, P.5
Liu, J.S.6
Kouzarides, T.7
Schreiber, S.L.8
-
243
-
-
34250159524
-
Genome-wide mapping of in vivo protein-DNA interactions
-
DOI 10.1126/science.1141319
-
Johnson DS, Mortazavi A, Myers RM, Wold B. Genome-wide mapping of in vivo protein-DNA interactions. Science 316(5830), 1497-1502 (2007). (Pubitemid 46906620)
-
(2007)
Science
, vol.316
, Issue.5830
, pp. 1497-1502
-
-
Johnson, D.S.1
Mortazavi, A.2
Myers, R.M.3
Wold, B.4
-
244
-
-
0041668072
-
Immunoprecipitation of native chromatin: NChIP
-
DOI 10.1016/S1046-2023(03)00090-2
-
O'Neill LP, Turner BM. Immunoprecipitation of native chromatin: NChIP. Methods 31(1), 76-82 (2003). (Pubitemid 36945173)
-
(2003)
Methods
, vol.31
, Issue.1
, pp. 76-82
-
-
O'Neill, L.P.1
Turner, B.M.2
-
245
-
-
63849091245
-
Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses
-
Fullwood MJ, Wei CL, Liu ET, Ruan Y. Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses. Genome Res. 19(4), 521-532 (2009).
-
(2009)
Genome Res
, vol.19
, Issue.4
, pp. 521-532
-
-
Fullwood, M.J.1
Wei, C.L.2
Liu, E.T.3
Ruan, Y.4
-
246
-
-
70449103609
-
An oestrogen-receptor-a-bound human chromatin interactome
-
Fullwood MJ, Liu MH, Pan YF et al. An oestrogen-receptor-a-bound human chromatin interactome. Nature 462(7269), 58-64 (2009).
-
(2009)
Nature
, vol.462
, Issue.7269
, pp. 58-64
-
-
Fullwood, M.J.1
Liu, M.H.2
Pan, Y.F.3
-
247
-
-
84857781464
-
Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization
-
Chepelev I, Wei G, Wangsa D, Tang Q, Zhao K. Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization. Cell Res. 22(3), 490-503 (2012).
-
(2012)
Cell Res
, vol.22
, Issue.3
, pp. 490-503
-
-
Chepelev, I.1
Wei, G.2
Wangsa, D.3
Tang, Q.4
Zhao, K.5
|