-
1
-
-
0036299092
-
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly
-
Ahmad K, Henikoff S (2002) The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell 9:1191-1200
-
(2002)
Mol Cell
, vol.9
, pp. 1191-1200
-
-
Ahmad, K.1
Henikoff, S.2
-
3
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, Zieger K, Guldberg P, Sehested M, Nesland JM, Lukas C, Orntoft T, Lukas J, Bartek J (2005) DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434:864-870
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zieger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
Orntoft, T.11
Lukas, J.12
Bartek, J.13
-
4
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Orntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG (2006) Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444:633-637
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
Vassiliou, L.V.7
Kolettas, E.8
Niforou, K.9
Zoumpourlis, V.C.10
Takaoka, M.11
Nakagawa, H.12
Tort, F.13
Fugger, K.14
Johansson, F.15
Sehested, M.16
Andersen, C.L.17
Dyrskjot, L.18
Orntoft, T.19
Lukas, J.20
Kittas, C.21
Helleday, T.22
Halazonetis, T.D.23
Bartek, J.24
Gorgoulis, V.G.25
more..
-
5
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
Beausejour CM, Krtolica A, Galimi F, Narita M, Lowe SW, Yaswen P, Campisi J (2003) Reversal of human cellular senescence: Roles of the p53 and p16 pathways. Embo J 22:4212-4222
-
(2003)
Embo J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yaswen, P.6
Campisi, J.7
-
6
-
-
14644410453
-
The signals and pathways activating cellular senescence
-
Ben-Porath I, Weinberg RA (2005) The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 37:961-976
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 961-976
-
-
Ben-Porath, I.1
Weinberg, R.A.2
-
7
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE (1998) Extension of life-span by introduction of telomerase into normal human cells. Science 279:349-352
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
8
-
-
23044500522
-
Human LATS1 is a mitotic exit network kinase
-
Bothos J, Tuttle RL, Ottey M, Luca FC, Halazonetis TD (2005) Human LATS1 is a mitotic exit network kinase. Cancer Res 65:6568-6575
-
(2005)
Cancer Res
, vol.65
, pp. 6568-6575
-
-
Bothos, J.1
Tuttle, R.L.2
Ottey, M.3
Luca, F.C.4
Halazonetis, T.D.5
-
9
-
-
33645526114
-
Oncogene-induced senescence: Putting the brakes on tumor development
-
Braig M, Schmitt CA (2006) Oncogene-induced senescence: Putting the brakes on tumor development. Cancer Res 66:2881-2884
-
(2006)
Cancer Res
, vol.66
, pp. 2881-2884
-
-
Braig, M.1
Schmitt, C.A.2
-
10
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dorken B, Jenuwein T, Schmitt CA (2005) Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436:660-665
-
(2005)
Nature
, vol.43
, pp. 660-665
-
-
Braig, M.1
Lee, S.2
Loddenkemper, C.3
Rudolph, C.4
Peters, A.H.5
Schlegelberger, B.6
Stein, H.7
Dorken, B.8
Jenuwein, T.9
Schmitt, C.A.10
-
11
-
-
0031802612
-
Identification of an interchromosomal compartment by polymerization of nuclear-targeted vimentin
-
Bridger JM, Herrmann H, Munkel C, Lichter P (1998) Identification of an interchromosomal compartment by polymerization of nuclear-targeted vimentin. J Cell Sci 111(Pt 9):1241-1253
-
(1998)
J Cell Sci
, vol.111
, Issue.PART 9
, pp. 1241-1253
-
-
Bridger, J.M.1
Herrmann, H.2
Munkel, C.3
Lichter, P.4
-
12
-
-
9244263033
-
Nuclear RNAs confined to a reticular compartment between chromosome territories
-
Bridger JM, Kalla C, Wodrich H, Weitz S, King JA, Khazaie K, Krausslich HG, Lichter P (2005) Nuclear RNAs confined to a reticular compartment between chromosome territories. Exp Cell Res 302:180-193
-
(2005)
Exp Cell Res
, vol.302
, pp. 180-193
-
-
Bridger, J.M.1
Kalla, C.2
Wodrich, H.3
Weitz, S.4
King, J.A.5
Khazaie, K.6
Krausslich, H.G.7
Lichter, P.8
-
13
-
-
0030609861
-
Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts
-
Brown JP, Wei W, Sedivy JM (1997) Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science 277:831-834
-
(1997)
Science
, vol.277
, pp. 831-834
-
-
Brown, J.P.1
Wei, W.2
Sedivy, J.M.3
-
14
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
Campisi J (2005) Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors. Cell 120:513-522
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
15
-
-
2942596544
-
Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin
-
Catez F, Yang H, Tracey KJ, Reeves R, Misteli T, Bustin M (2004) Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin. Mol Cell Biol 24:4321-4328
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4321-4328
-
-
Catez, F.1
Yang, H.2
Tracey, K.J.3
Reeves, R.4
Misteli, T.5
Bustin, M.6
-
16
-
-
12144283456
-
The p400 E1A-associated protein is a novel component of the p53 -> p21 senescence pathway
-
Chan HM, Narita M, Lowe SW, Livingston DM (2005) The p400 E1A-associated protein is a novel component of the p53 -> p21 senescence pathway. Genes Dev 19:196-201
-
(2005)
Genes Dev
, vol.19
, pp. 196-201
-
-
Chan, H.M.1
Narita, M.2
Lowe, S.W.3
Livingston, D.M.4
-
17
-
-
34147136796
-
Developmental changes in histone macroH2A1 mediated gene regulation
-
Changolkar LN, Costanzi C, Leu NA, Chen D, McLaughlin KJ, Pehrson JR (2007) Developmental changes in histone macroH2A1 mediated gene regulation. Mol Cell Biol 27:2758-2764
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2758-2764
-
-
Changolkar, L.N.1
Costanzi, C.2
Leu, N.A.3
Chen, D.4
McLaughlin, K.J.5
Pehrson, J.R.6
-
18
-
-
0028345161
-
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
-
Chen Q, Ames BN (1994) Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc Natl Acad Sci USA 91:4130-4134
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4130-4134
-
-
Chen, Q.1
Ames, B.N.2
-
19
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436:725-730
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
Lin, H.K.4
Dotan, Z.A.5
Niki, M.6
Koutcher, J.A.7
Scher, H.I.8
Ludwig, T.9
Gerald, W.10
Cordon-Cardo, C.11
Pandolfi, P.P.12
-
20
-
-
23244447893
-
Tumour biology: Senescence in premalignant tumours
-
Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguria A, Zaballos A, Flores JM, Barbacid M, Beach D, Serrano M (2005) Tumour biology: Senescence in premalignant tumours. Nature 436:642
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
Gil, J.2
Efeyan, A.3
Guerra, C.4
Schuhmacher, A.J.5
Barradas, M.6
Benguria, A.7
Zaballos, A.8
Flores, J.M.9
Barbacid, M.10
Beach, D.11
Serrano, M.12
-
21
-
-
0032507949
-
Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals
-
Costanzi C, Pehrson JR (1998) Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals. Nature 393:599-601
-
(1998)
Nature
, vol.393
, pp. 599-601
-
-
Costanzi, C.1
Pehrson, J.R.2
-
22
-
-
33646526019
-
Chromosome territories-a functional nuclear landscape
-
Cremer T, Cremer M, Dietzel S, Muller S, Solovei I, Fakan S (2006) Chromosome territories-a functional nuclear landscape. Curr Opin Cell Biol 18:307-316
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 307-316
-
-
Cremer, T.1
Cremer, M.2
Dietzel, S.3
Muller, S.4
Solovei, I.5
Fakan, S.6
-
23
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP (2003) A DNA damage checkpoint response in telomere-initiated senescence. Nature 426:194-198
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
d'Adda di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
Fiegler, H.4
Carr, P.5
Von Zglinicki, T.6
Saretzki, G.7
Carter, N.P.8
Jackson, S.P.9
-
24
-
-
33749184798
-
Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
-
Denoyelle C, Abou-Rjaily G, Bezrookove V, Verhaegen M, Johnson TM, Fullen DR, Pointer JN, Gruber SB, Su LD, Nikiforov MA, Kaufman RJ, Bastian BC, Soengas MS (2006) Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat Cell Biol 8:1053-1063
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1053-1063
-
-
Denoyelle, C.1
Abou-Rjaily, G.2
Bezrookove, V.3
Verhaegen, M.4
Johnson, T.M.5
Jullen, D.R.6
Pointer, J.N.7
Gruber, S.B.8
Su, L.D.9
Nikiforov, M.A.10
Kaufman, R.J.11
Bastian, B.C.12
Soengas, M.S.13
-
25
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, d'Adda di Fagagna F (2006) Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444:638-642
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre, M.8
Nuciforo, P.G.9
Bensimon, A.10
Maestro, R.11
Pelicci, P.G.12
d'Adda di Fagagna, F.13
-
26
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O et al (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92:9363-9367
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
27
-
-
0032146274
-
The regulation of E2F by pRB-family proteins Genes
-
Dyson N (1998) The regulation of E2F by pRB-family proteins. Genes Dev 12:2245-2262
-
(1998)
Dev
, vol.12
, pp. 2245-2262
-
-
Dyson, N.1
-
28
-
-
2142666372
-
Developmental differences in the immortalization of lung fibroblasts by telomerase
-
Forsyth NR, Evans AP, Shay JW, Wright WE (2003) Developmental differences in the immortalization of lung fibroblasts by telomerase. Aging Cell 2:235-243
-
(2003)
Aging Cell
, vol.2
, pp. 235-243
-
-
Forsyth, N.R.1
Evans, A.P.2
Shay, J.W.3
Wright, W.E.4
-
30
-
-
0026643104
-
The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures
-
Giese K, Cox J, Grosschedl R (1992) The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell 69:185-195
-
(1992)
Cell
, vol.69
, pp. 185-195
-
-
Giese, K.1
Cox, J.2
Grosschedl, R.3
-
31
-
-
33747587608
-
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all
-
Gil J, Peters G (2006) Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all. Nat Rev Mol Cell Biol 7:667-677
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 667-677
-
-
Gil, J.1
Peters, G.2
-
32
-
-
3342929538
-
DNA damage checkpoint kinase Chk2 triggers replicative senescence
-
Gire V, Roux P, Wynford-Thomas D, Brondello JM, Dulic V (2004) DNA damage checkpoint kinase Chk2 triggers replicative senescence. Embo J 23:2554-2563
-
(2004)
Embo J
, vol.23
, pp. 2554-2563
-
-
Gire, V.1
Roux, P.2
Wynford-Thomas, D.3
Brondello, J.M.4
Dulic, V.5
-
33
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, Venere M, Ditullio RA Jr, Kastrinakis NG, Levy B, Kletsas D, Yoneta A, Herlyn M, Kittas C, Halazonetis TD (2005) Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434:907-913
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
Ditullio Jr., R.A.8
Kastrinakis, N.G.9
Levy, B.10
Kletsas, D.11
Yoneta, A.12
Herlyn, M.13
Kittas, C.14
Halazonetis, T.D.15
-
34
-
-
0022257331
-
Reinitiation of cellular DNA synthesis in BrdU-selected nondividing senescent WI-38 cells by simian virus 40 infection
-
Gorman SD, Cristofalo VJ (1985) Reinitiation of cellular DNA synthesis in BrdU-selected nondividing senescent WI-38 cells by simian virus 40 infection. J Cell Physiol 125:122-126
-
(1985)
J Cell Physiol
, vol.125
, pp. 122-126
-
-
Gorman, S.D.1
Cristofalo, V.J.2
-
35
-
-
0041883654
-
Tumor induction by an endogenous K- ras oncogene is highly dependent on cellular context
-
Guerra C, Mijimolle N, Dhawahir A, Dubus P, Barradas M, Serrano M, Campuzano V, Barbacid M (2003) Tumor induction by an endogenous K- ras oncogene is highly dependent on cellular context. Cancer Cell 4:111-120
-
(2003)
Cancer Cell
, vol.4
, pp. 111-120
-
-
Guerra, C.1
Mijimolle, N.2
Dhawahir, A.3
Dubus, P.4
Barradas, M.5
Serrano, M.6
Campuzano, V.7
Barbacid, M.8
-
36
-
-
0029670840
-
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
-
Hara E, Smith R, Parry D, Tahara H, Stone S, Peters G (1996) Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol Cell Biol 16:859-867
-
(1996)
Mol Cell Biol
, vol.16
, pp. 859-867
-
-
Hara, E.1
Smith, R.2
Parry, D.3
Tahara, H.4
Stone, S.5
Peters, G.6
-
37
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345:458-460
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
38
-
-
0027179908
-
In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice
-
Harvey M, Sands AT, Weiss RS, Hegi ME, Wiseman RW, Pantazis P, Giovanella BC, Tainsky MA, Bradley A, Donehower LA (1993) In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice. Oncogene 8:2457-2467
-
(1993)
Oncogene
, vol.8
, pp. 2457-2467
-
-
Harvey, M.1
Sands, A.T.2
Weiss, R.S.3
Hegi, M.E.4
Wiseman, R.W.5
Pantazis, P.6
Giovanella, B.C.7
Tainsky, M.A.8
Bradley, A.9
Donehower, L.A.10
-
40
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25:585-621
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
41
-
-
21144446865
-
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase
-
Hernandez-Munoz I, Lund AH, van der Stoop P, Boutsma E, Muijrers I, Verhoeven E, Nusinow DA, Panning B, Marahrens Y, van Lohuizen M (2005) Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase. Proc Natl Acad Sci USA 102:7635-7640
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 7635-7640
-
-
Hernandez-Munoz, I.1
Lund, A.H.2
van der Stoop, P.3
Boutsma, E.4
Muijrers, I.5
Verhoeven, E.6
Nusinow, D.A.7
Panning, B.8
Marahrens, Y.9
van Lohuizen, M.10
-
42
-
-
0036724625
-
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
-
Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ, Mak TW (2002) Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol 22:6521-6532
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6521-6532
-
-
Hirao, A.1
Cheung, A.2
Duncan, G.3
Girard, P.M.4
Elia, A.J.5
Wakeham, A.6
Okada, H.7
Sarkissian, T.8
Wong, J.A.9
Sakai, T.10
De Stanchina, E.11
Bristow, R.G.12
Suda, T.13
Lowe, S.W.14
Jeggo, P.A.15
Elledge, S.J.16
Mak, T.W.17
-
44
-
-
3142711698
-
Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function
-
Iida S, Hirota T, Morisaki T, Marumoto T, Hara T, Kuninaka S, Honda S, Kosai K, Kawasuji M, Pallas DC, Saya H (2004) Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function. Oncogene 23:5266-5274
-
(2004)
Oncogene
, vol.23
, pp. 5266-5274
-
-
Iida, S.1
Hirota, T.2
Morisaki, T.3
Marumoto, T.4
Hara, T.5
Kuninaka, S.6
Honda, S.7
Kosai, K.8
Kawasuji, M.9
Pallas, D.C.10
Saya, H.11
-
45
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ (1997) Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275:1649-1652
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
46
-
-
0345099455
-
Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism
-
Ishikawa F (2003) Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism. Cancer Sci 94:944-947
-
(2003)
Cancer Sci
, vol.94
, pp. 944-947
-
-
Ishikawa, F.1
-
47
-
-
0345932931
-
Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway
-
Iwasa H, Han J, Ishikawa F (2003) Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells 8:131-144
-
(2003)
Genes Cells
, vol.8
, pp. 131-144
-
-
Iwasa, H.1
Han, J.2
Ishikawa, F.3
-
48
-
-
10744233286
-
Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks
-
Konishi A, Shimizu S, Hirota J, Takao T, Fan Y, Matsuoka Y, Zhang L, Yoneda Y, Fujii Y, Skoultchi AI, Tsujimoto Y (2003) Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks. Cell 114:673-688
-
(2003)
Cell
, vol.114
, pp. 673-688
-
-
Konishi, A.1
Shimizu, S.2
Hirota, J.3
Takao, T.4
Fan, Y.5
Matsuoka, Y.6
Zhang, L.7
Yoneda, Y.8
Fujii, Y.9
Skoultchi, A.I.10
Tsujimoto, Y.11
-
49
-
-
0036829090
-
Cancer and aging: A model for the cancer promoting effects of the aging stroma
-
Krtolica A, Campisi J (2002) Cancer and aging: A model for the cancer promoting effects of the aging stroma. Int J Biochem Cell Biol 34:1401-1414
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1401-1414
-
-
Krtolica, A.1
Campisi, J.2
-
50
-
-
15044351968
-
Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland
-
Lazzerini Denchi E, Attwooll C, Pasini D, Helin K (2005) Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland. Mol Cell Biol 25:2660-2672
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2660-2672
-
-
Lazzerini Denchi, E.1
Attwooll, C.2
Pasini, D.3
Helin, K.4
-
51
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, Hirai T, Yu ZX, Ferrans VJ, Howard BH, Finkel T (1999) Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J Biol Chem 274:7936-7940
-
(1999)
J Biol Chem
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
-
52
-
-
33846128155
-
The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence
-
Mallette FA, Gaumont-Leclerc MF, Ferbeyre G (2007) The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. Genes Dev 21:43-48
-
(2007)
Genes Dev
, vol.21
, pp. 43-48
-
-
Mallette, F.A.1
Gaumont-Leclerc, M.F.2
Ferbeyre, G.3
-
53
-
-
0141482100
-
Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells
-
Meng A, Wang Y, Van Zant G, Zhou D (2003) Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells. Cancer Res 63:5414-5419
-
(2003)
Cancer Res
, vol.63
, pp. 5414-5419
-
-
Meng, A.1
Wang, Y.2
Van Zant, G.3
Zhou, D.4
-
54
-
-
23244447037
-
BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, Majoor DM, Shay JW, Mooi WJ, Peeper DS (2005) BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature 436:720-724
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.C.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
van der Horst, C.M.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
Peeper, D.S.10
-
55
-
-
0019308155
-
Age-related decline in histone H1 fraction in human diploid fibroblast cultures
-
Mitsui Y, Sakagami H, Murota S, Yamada M (1980) Age-related decline in histone H1 fraction in human diploid fibroblast cultures. Exp Cell Res 126:289-298
-
(1980)
Exp Cell Res
, vol.126
, pp. 289-298
-
-
Mitsui, Y.1
Sakagami, H.2
Murota, S.3
Yamada, M.4
-
56
-
-
0037108055
-
Histone chaperone ASF1 cooperates with the Brahma chromatin-remodelling machinery
-
Moshkin YM, Armstrong JA, Maeda RK, Tamkun JW, Verrijzer P, Kennison JA, Karch F (2002) Histone chaperone ASF1 cooperates with the Brahma chromatin-remodelling machinery. Genes Dev 16:2621-2626
-
(2002)
Genes Dev
, vol.16
, pp. 2621-2626
-
-
Moshkin, Y.M.1
Armstrong, J.A.2
Maeda, R.K.3
Tamkun, J.W.4
Verrijzer, P.5
Kennison, J.A.6
Karch, F.7
-
57
-
-
33947127598
-
The histone chaperone Asf1 at the crossroads of chromatin and DNA checkpoint pathways
-
Mousson F, Ochsenbein F, Mann C (2007) The histone chaperone Asf1 at the crossroads of chromatin and DNA checkpoint pathways. Chromosoma 116:79-93
-
(2007)
Chromosoma
, vol.116
, pp. 79-93
-
-
Mousson, F.1
Ochsenbein, F.2
Mann, C.3
-
58
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, Nunez S, Heard E, Narita M, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW (2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113:703-716
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
59
-
-
33746752125
-
A novel role for high-mobility group A proteins in cellular senescence and heterochromatin formation
-
Narita M, Narita M, Krizhanovsky V, Nunez S, Chicas A, Hearn SA, Myers MP, Lowe SW (2006) A novel role for high-mobility group A proteins in cellular senescence and heterochromatin formation. Cell 126:503-514
-
(2006)
Cell
, vol.126
, pp. 503-514
-
-
Narita, M.1
Narita, M.2
Krizhanovsky, V.3
Nunez, S.4
Chicas, A.5
Hearn, S.A.6
Myers, M.P.7
Lowe, S.W.8
-
60
-
-
0032526694
-
PRAK, a novel protein kinase regulated by the p38 MAP kinase
-
New L, Jiang Y, Zhao M, Liu K, Zhu W, Flood LJ, Kato Y, Parry GC, Han J (1998) PRAK, a novel protein kinase regulated by the p38 MAP kinase. Embo J 17:3372-3384
-
(1998)
Embo J
, vol.17
, pp. 3372-3384
-
-
New, L.1
Jiang, Y.2
Zhao, M.3
Liu, K.4
Zhu, W.5
Flood, L.J.6
Kato, Y.7
Parry, G.C.8
Han, J.9
-
61
-
-
0029778901
-
Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
-
Ogryzko VV, Hirai TH, Russanova VR, Barbie DA, Howard BH (1996) Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol Cell Biol 16:5210-5218
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5210-5218
-
-
Ogryzko, V.V.1
Hirai, T.H.2
Russanova, V.R.3
Barbie, D.A.4
Howard, B.H.5
-
62
-
-
0035931859
-
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
-
Ohtani N, Zebedee Z, Huot TJ, Stinson JA, Sugimoto M, Ohashi Y, Sharrocks AD, Peters G, Hara E (2001) Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature 409:1067-1070
-
(2001)
Nature
, vol.409
, pp. 1067-1070
-
-
Ohtani, N.1
Zebedee, Z.2
Huot, T.J.3
Stinson, J.A.4
Sugimoto, M.5
Ohashi, Y.6
Sharrocks, A.D.7
Peters, G.8
Hara, E.9
-
63
-
-
0027216519
-
The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures
-
Paull TT, Haykinson MJ, Johnson RC (1993) The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures. Genes Dev 7:1521-1534
-
(1993)
Genes Dev
, vol.7
, pp. 1521-1534
-
-
Paull, T.T.1
Haykinson, M.J.2
Johnson, R.C.3
-
64
-
-
0035114576
-
Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
-
Ramirez RD, Morales CP, Herbert BS, Rohde JM, Passons C, Shay JW, Wright WE (2001) Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev 15:398-403
-
(2001)
Genes Dev
, vol.15
, pp. 398-403
-
-
Ramirez, R.D.1
Morales, C.P.2
Herbert, B.S.3
Rohde, J.M.4
Passons, C.5
Shay, J.W.6
Wright, W.E.7
-
65
-
-
33646877911
-
Prohibitin facilitates cellular senescence by recruiting specific corepressors to inhibit E2F target genes
-
Rastogi S, Joshi B, Dasgupta P, Morris M, Wright K, Chellappan S (2006) Prohibitin facilitates cellular senescence by recruiting specific corepressors to inhibit E2F target genes. Mol Cell Biol 26:4161-4171
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4161-4171
-
-
Rastogi, S.1
Joshi, B.2
Dasgupta, P.3
Morris, M.4
Wright, K.5
Chellappan, S.6
-
66
-
-
0035904395
-
Molecular biology of HMGA proteins: Hubs of nuclear function
-
Reeves R (2001) Molecular biology of HMGA proteins: Hubs of nuclear function. Gene 277:63-81
-
(2001)
Gene
, vol.277
, pp. 63-81
-
-
Reeves, R.1
-
67
-
-
0035962921
-
HMGI/Y proteins: Flexible regulators of transcription and chromatin structure
-
Reeves R, Beckerbauer L (2001) HMGI/Y proteins: Flexible regulators of transcription and chromatin structure. Biochim Biophys Acta 1519:13-29
-
(2001)
Biochim Biophys Acta
, vol.1519
, pp. 13-29
-
-
Reeves, R.1
Beckerbauer, L.2
-
68
-
-
0032846669
-
Histone variants of H2A and H3 families are regulated during in vitro aging in the same manner as during differentiation
-
Rogakou EP, Sekeri-Pataryas KE (1999) Histone variants of H2A and H3 families are regulated during in vitro aging in the same manner as during differentiation. Exp Gerontol 34:741-754
-
(1999)
Exp Gerontol
, vol.34
, pp. 741-754
-
-
Rogakou, E.P.1
Sekeri-Pataryas, K.E.2
-
69
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
Sage J, Mulligan GJ, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, Jacks T (2000) Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev 14:3037-3050
-
(2000)
Genes Dev
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
Williams, B.6
Theodorou, E.7
Jacks, T.8
-
70
-
-
0028915601
-
The effect of low oxygen tension on the in vitro-replicative life span of human diploid fibroblast cells and their transformed derivatives
-
Saito H, Hammond AT, Moses RE (1995) The effect of low oxygen tension on the in vitro-replicative life span of human diploid fibroblast cells and their transformed derivatives. Exp Cell Res 217:272-279
-
(1995)
Exp Cell Res
, vol.217
, pp. 272-279
-
-
Saito, H.1
Hammond, A.T.2
Moses, R.E.3
-
71
-
-
0038013875
-
Senescence, apoptosis and therapy-Cutting the lifelines of cancer
-
Schmitt CA (2003) Senescence, apoptosis and therapy-cutting the lifelines of cancer. Nat Rev Cancer 3:286-295
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 286-295
-
-
Schmitt, C.A.1
-
72
-
-
17044394787
-
Transcriptional activation triggers deposition and removal of the histone variant H3.3
-
Schwartz BE, Ahmad K (2005) Transcriptional activation triggers deposition and removal of the histone variant H3.3. Genes Dev 19:804-814
-
(2005)
Genes Dev
, vol.19
, pp. 804-814
-
-
Schwartz, B.E.1
Ahmad, K.2
-
73
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88:593-602
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
74
-
-
0035799281
-
Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing
-
Sharp JA, Fouts ET, Krawitz DC, Kaufman PD (2001) Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing. Curr Biol 11:463-473
-
(2001)
Curr Biol
, vol.11
, pp. 463-473
-
-
Sharp, J.A.1
Fouts, E.T.2
Krawitz, D.C.3
Kaufman, P.D.4
-
75
-
-
0026054961
-
A role for both RB and p53 in the regulation of human cellular senescence
-
Shay JW, Pereira-Smith OM, Wright WE (1991) A role for both RB and p53 in the regulation of human cellular senescence. Exp Cell Res 196:33-39
-
(1991)
Exp Cell Res
, vol.196
, pp. 33-39
-
-
Shay, J.W.1
Pereira-Smith, O.M.2
Wright, W.E.3
-
76
-
-
0037102234
-
Different telomere damage signaling pathways in human and mouse cells
-
Smogorzewska A, de Lange T (2002) Different telomere damage signaling pathways in human and mouse cells. Embo J 21:4338-4348
-
(2002)
Embo J
, vol.21
, pp. 4338-4348
-
-
Smogorzewska, A.1
de Lange, T.2
-
77
-
-
33846282393
-
PRAK is essential for ras-induced senescence and tumor suppression
-
Sun P, Yoshizuka N, New L, Moser BA, Li Y, Liao R, Xie C, Chen J, Deng Q, Yamout M, Dong MQ, Frangou CG, Yates JR III, Wright PE, Han J (2007) PRAK is essential for ras-induced senescence and tumor suppression. Cell 128:295-308
-
(2007)
Cell
, vol.128
, pp. 295-308
-
-
Sun, P.1
Yoshizuka, N.2
New, L.3
Moser, B.A.4
Li, Y.5
Liao, R.6
Xie, C.7
Chen, J.8
Deng, Q.9
Yamout, M.10
Dong, M.Q.11
Frangou, C.G.12
Yates III, J.R.13
Wright, P.E.14
Han, J.15
-
78
-
-
0742304304
-
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis
-
Tagami H, Ray-Gallet D, Almouzni G, Nakatani Y (2004) Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell 116:51-61
-
(2004)
Cell
, vol.116
, pp. 51-61
-
-
Tagami, H.1
Ray-Gallet, D.2
Almouzni, G.3
Nakatani, Y.4
-
79
-
-
33750510904
-
Mitogenic signalling and the p16(INK4a)-Rb pathway cooperate to enforce irreversible cellular senescence
-
Takahashi A, Ohtani N, Yamakoshi K, Iida S, Tahara H, Nakayama K, Nakayama KI, Ide T, Saya H, Hara E (2006) Mitogenic signalling and the p16(INK4a)-Rb pathway cooperate to enforce irreversible cellular senescence. Nat Cell Biol 8:1291-1297
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1291-1297
-
-
Takahashi, A.1
Ohtani, N.2
Yamakoshi, K.3
Iida, S.4
Tahara, H.5
Nakayama, K.6
Nakayama, K.I.7
Ide, T.8
Saya, H.9
Hara, E.10
-
80
-
-
4644266046
-
Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction
-
Takaoka M, Harada H, Deramaudt TB, Oyama K, Andl CD, Johnstone CN, Rhoades B, Enders GH, Opitz OG, Nakagawa H (2004) Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction. Oncogene 23:6760-6768
-
(2004)
Oncogene
, vol.23
, pp. 6760-6768
-
-
Takaoka, M.1
Harada, H.2
Deramaudt, T.B.3
Oyama, K.4
Andl, C.D.5
Johnstone, C.N.6
Rhoades, B.7
Enders, G.H.8
Opitz, O.G.9
Nakagawa, H.10
-
81
-
-
0242464153
-
HBP1: A HMG box transcriptional repressor that is targeted by the retinoblastoma family
-
Tevosian SG, Shih HH, Mendelson KG, Sheppard KA, Paulson KE, Yee AS (1997) HBP1: A HMG box transcriptional repressor that is targeted by the retinoblastoma family. Genes Dev 11:383-396
-
(1997)
Genes Dev
, vol.11
, pp. 383-396
-
-
Tevosian, S.G.1
Shih, H.H.2
Mendelson, K.G.3
Sheppard, K.A.4
Paulson, K.E.5
Yee, A.S.6
-
82
-
-
0018581187
-
Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin
-
Thoma F, Koller T, Klug A (1979) Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin. J Cell Biol 83:403-427
-
(1979)
J Cell Biol
, vol.83
, pp. 403-427
-
-
Thoma, F.1
Koller, T.2
Klug, A.3
-
83
-
-
0030876483
-
Induction of senescence in human malignant glioma cells by p16INK4A
-
Uhrbom L, Nister M, Westermark B (1997) Induction of senescence in human malignant glioma cells by p16INK4A. Oncogene 15:505-514
-
(1997)
Oncogene
, vol.15
, pp. 505-514
-
-
Uhrbom, L.1
Nister, M.2
Westermark, B.3
-
84
-
-
11144284688
-
Proteasome inhibitors induce changes in chromatin structure characteristic of senescent human fibroblasts
-
Ukekawa R, Maegawa N, Mizutani E, Fujii M, Ayusawa D (2004) Proteasome inhibitors induce changes in chromatin structure characteristic of senescent human fibroblasts. Biosci Biotechnol Biochem 68:2395-2397
-
(2004)
Biosci Biotechnol Biochem
, vol.68
, pp. 2395-2397
-
-
Ukekawa, R.1
Maegawa, N.2
Mizutani, E.3
Fujii, M.4
Ayusawa, D.5
-
85
-
-
0036285034
-
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
-
Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, Wahl GM (2002) c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability. Mol Cell 9:1031-1044
-
(2002)
Mol Cell
, vol.9
, pp. 1031-1044
-
-
Vafa, O.1
Wade, M.2
Kern, S.3
Beeche, M.4
Pandita, T.K.5
Hampton, G.M.6
Wahl, G.M.7
-
86
-
-
25644440744
-
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
-
Varela I, Cadinanos J, Pendas AM, Gutierrez-Fernandez A, Folgueras AR, Sanchez LM, Zhou Z, Rodriguez FJ, Stewart CL, Vega JA, Tryggvason K, Freije JM, Lopez-Otin C (2005) Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature 437:564-568
-
(2005)
Nature
, vol.437
, pp. 564-568
-
-
Varela, I.1
Cadinanos, J.2
Pendas, A.M.3
Gutierrez-Fernandez, A.4
Folgueras, A.R.5
Sanchez, L.M.6
Zhou, Z.7
Rodriguez, F.J.8
Stewart, C.L.9
Vega, J.A.10
Tryggvason, K.11
Freije, J.M.12
Lopez-Otin, C.13
-
87
-
-
0036242247
-
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
-
Wang W, Chen JX, Liao R, Deng Q, Zhou JJ, Huang S, Sun P (2002) Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol Cell Biol 22:3389-3403
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3389-3403
-
-
Wang, W.1
Chen, J.X.2
Liao, R.3
Deng, Q.4
Zhou, J.J.5
Huang, S.6
Sun, P.7
-
88
-
-
0034114544
-
Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage
-
Webley K, Bond JA, Jones CJ, Blaydes JP, Craig A, Hupp T, Wynford-Thomas D (2000) Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage. Mol Cell Biol 20:2803-2808
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2803-2808
-
-
Webley, K.1
Bond, J.A.2
Jones, C.J.3
Blaydes, J.P.4
Craig, A.5
Hupp, T.6
Wynford-Thomas, D.7
-
89
-
-
0346873027
-
Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts
-
Wei W, Herbig U, Wei S, Dutriaux A, Sedivy JM (2003) Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts. EMBO Rep 4:1061-1066
-
(2003)
EMBO Rep
, vol.4
, pp. 1061-1066
-
-
Wei, W.1
Herbig, U.2
Wei, S.3
Dutriaux, A.4
Sedivy, J.M.5
-
90
-
-
0043180471
-
Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes
-
Weierich C, Brero A, Stein S, von Hase J, Cremer C, Cremer T, Solovei I (2003) Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res 11:485-502
-
(2003)
Chromosome Res
, vol.11
, pp. 485-502
-
-
Weierich, C.1
Brero, A.2
Stein, S.3
von Hase, J.4
Cremer, C.5
Cremer, T.6
Solovei, I.7
-
91
-
-
0035989631
-
Historical claims and current interpretations of replicative aging
-
Wright WE, Shay JW (2002) Historical claims and current interpretations of replicative aging. Nat Biotechnol 20:682-688
-
(2002)
Nat Biotechnol
, vol.20
, pp. 682-688
-
-
Wright, W.E.1
Shay, J.W.2
-
92
-
-
3242689902
-
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1
-
Yang X, Yu K, Hao Y, Li DM, Stewart R, Insogna KL, Xu T (2004) LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1. Nat Cell Biol 6:609-617
-
(2004)
Nat Cell Biol
, vol.6
, pp. 609-617
-
-
Yang, X.1
Yu, K.2
Hao, Y.3
Li, D.M.4
Stewart, R.5
Insogna, K.L.6
Xu, T.7
-
93
-
-
34147143631
-
Definition of pRB- and p53-dependent and independent steps in HIRA/ ASF1a-mediated formation of senescence-associated heterochromatin foci (SAHF)
-
Ye X, Zerlanko B, Zhang R, Somaiah N, Lipinski M, Salomoni P, Adams PD (2007) Definition of pRB- and p53-dependent and independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci (SAHF). Mol Cell Biol 27:2452-2465
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2452-2465
-
-
Ye, X.1
Zerlanko, B.2
Zhang, R.3
Somaiah, N.4
Lipinski, M.5
Salomoni, P.6
Adams, P.D.7
-
94
-
-
19944427674
-
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
-
Zhang R, Poustovoitov MV, Ye X, Santos HA, Chen W, Daganzo SM, Erzberger JP, Serebriiskii IG, Canutescu AA, Dunbrack RL, Pehrson JR, Berger JM, Kaufman PD, Adams PD (2005) Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev Cell 8:19-30
-
(2005)
Dev Cell
, vol.8
, pp. 19-30
-
-
Zhang, R.1
Poustovoitov, M.V.2
Ye, X.3
Santos, H.A.4
Chen, W.5
Daganzo, S.M.6
Erzberger, J.P.7
Serebriiskii, I.G.8
Canutescu, A.A.9
Dunbrack, R.L.10
Pehrson, J.R.11
Berger, J.M.12
Kaufman, P.D.13
Adams, P.D.14
-
95
-
-
33750987923
-
The HBP1 transcriptional repressor participates in RAS-induced premature senescence
-
Zhang X, J, Kim R, Ruthazer MA, McDevitt DE, Wazer KE, Paulson AS, Yee (2006) The HBP1 transcriptional repressor participates in RAS-induced premature senescence. Mol Cell Biol 26:8252-8266
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8252-8266
-
-
Zhang, X.J.1
Kim, R.2
Ruthazer, M.A.3
McDevitt, D.E.4
Wazer, K.E.5
Paulson, A.S.6
Yee7
-
96
-
-
33947236204
-
Molecular dissection of formation of senescent associated heterochromatin foci
-
Zhang R, Chen W, Adams PD (2007a) Molecular dissection of formation of senescent associated heterochromatin foci. Mol Cell Biol 27:2343-2358
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2343-2358
-
-
Zhang, R.1
Chen, W.2
Adams, P.D.3
-
97
-
-
33846604273
-
HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells
-
Zhang R, Liu ST, Chen W, Bonner M, Pehrson J, Yen TJ, Adams PD (2007b) HP1 proteins are essential for a dynamic nuclear response that rescues the function of perturbed heterochromatin in primary human cells. Mol Cell Biol 27:949-962
-
(2007)
Mol Cell Biol
, vol.27
, pp. 949-962
-
-
Zhang, R.1
Liu, S.T.2
Chen, W.3
Bonner, M.4
Pehrson, J.5
Yen, T.J.6
Adams, P.D.7
-
98
-
-
0027633886
-
Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries
-
Zirbel RM, Mathieu UR, Kurz A, Cremer T, Lichter P (1993) Evidence for a nuclear compartment of transcription and splicing located at chromosome domain boundaries. Chromosome Res 1:93-106
-
(1993)
Chromosome Res
, vol.1
, pp. 93-106
-
-
Zirbel, R.M.1
Mathieu, U.R.2
Kurz, A.3
Cremer, T.4
Lichter, P.5
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