-
1
-
-
0037924433
-
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene
-
Bachman, K. E., Park, B. H., Rhee, I., Rajagopalan, H., Herman, J. G., Baylin, S. B., Kinzler, K. W. and Vogelstein, B. (2003) Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene. Cancer Cell, 3, 89-95.
-
(2003)
Cancer Cell
, vol.3
, pp. 89-95
-
-
Bachman, K.E.1
Park, B.H.2
Rhee, I.3
Rajagopalan, H.4
Herman, J.G.5
Baylin, S.B.6
Kinzler, K.W.7
Vogelstein, B.8
-
2
-
-
18144415066
-
Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter
-
Strunnikova, M., Schagdarsurengin, U., Kehlen, A., Garbe, J. C., Stampfer, M. R. and Dammann, R. (2005) Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter. Mol. Cell. Biol., 25, 3923-3933.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 3923-3933
-
-
Strunnikova, M.1
Schagdarsurengin, U.2
Kehlen, A.3
Garbe, J.C.4
Stampfer, M.R.5
Dammann, R.6
-
3
-
-
10744230544
-
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
-
Lehnertz, B., Ueda, Y., Derijck, A. A. H. A., Braunschweig, U., Perez-Burgos, L., Kubicek, S., Chen, T., Li, E., Jenuwein, T. and Peters, A. H. F. M. (2003) Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr. Biol., 13, 1192-1200.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1192-1200
-
-
Lehnertz, B.1
Ueda, Y.2
Derijck, A.A.H.A.3
Braunschweig, U.4
Perez-Burgos, L.5
Kubicek, S.6
Chen, T.7
Li, E.8
Jenuwein, T.9
Peters, A.H.F.M.10
-
4
-
-
31444436545
-
Lsh is involved in de novo methylation of DNA
-
Zhu, H., Geiman, T. M., Xi, S., Jiang, Q., Schmidtmann, A., Chen, T., Li, E. and Muegge, K. (2006) Lsh is involved in de novo methylation of DNA. EMBO J., 25, 335-345.
-
(2006)
EMBO J.
, vol.25
, pp. 335-345
-
-
Zhu, H.1
Geiman, T.M.2
Xi, S.3
Jiang, Q.4
Schmidtmann, A.5
Chen, T.6
Li, E.7
Muegge, K.8
-
5
-
-
33751523649
-
Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells
-
De La Fuente, R., Baumann, C., Fan, T., Schmidtmann, A., Dobrinski, I. and Muegge, K. (2006) Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells. Nat. Cell Biol., 8, 1448-1454.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1448-1454
-
-
De La Fuente, R.1
Baumann, C.2
Fan, T.3
Schmidtmann, A.4
Dobrinski, I.5
Muegge, K.6
-
6
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen, T., Ueda, Y., Dodge, J. E., Wang, Z. and Li, E. (2003) Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell. Biol., 23, 5594-5605.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
7
-
-
4744366752
-
The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin
-
Chen, T., Tsujimoto, N. and Li, E. (2004) The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Mol. Cell. Biol., 24, 9048-9058.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9048-9058
-
-
Chen, T.1
Tsujimoto, N.2
Li, E.3
-
8
-
-
0037068351
-
Gene silencing in mammalian cells and the spread of DNA methylation
-
Turker, M. S. (2002) Gene silencing in mammalian cells and the spread of DNA methylation. Oncogene, 21, 5388-5393.
-
(2002)
Oncogene
, vol.21
, pp. 5388-5393
-
-
Turker, M.S.1
-
9
-
-
25844530426
-
Epigenetic changes in solid and hematopoietic tumors
-
Toyota, M. and Issa, J.-P. J. (2005) Epigenetic changes in solid and hematopoietic tumors. Semin. Oncol., 32, 521-530.
-
(2005)
Semin. Oncol.
, vol.32
, pp. 521-530
-
-
Toyota, M.1
Issa, J.-P.J.2
-
11
-
-
33748805480
-
Spreading of silent chromatin: Inaction at a distance
-
Talbert, P. B. and Henikoff, S. (2006) Spreading of silent chromatin: inaction at a distance. Nat. Rev. Genet., 7, 793-803.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 793-803
-
-
Talbert, P.B.1
Henikoff, S.2
-
12
-
-
53149107845
-
Chromatin insulators: Regulatory mechanisms and epigenetic inheritance
-
Bushey, A. M., Dorman, E. R. and Corces, V. G. (2008) Chromatin insulators: regulatory mechanisms and epigenetic inheritance. Mol. Cell, 32, 1-9.
-
(2008)
Mol. Cell
, vol.32
, pp. 1-9
-
-
Bushey, A.M.1
Dorman, E.R.2
Corces, V.G.3
-
13
-
-
0037301560
-
Origin of a substantial fraction of human regulatory sequences from transposable elements
-
Jordan, I. K., Rogozin, I. B., Glazko, G. V. and Koonin, E. V. (2003) Origin of a substantial fraction of human regulatory sequences from transposable elements. Trends Genet., 19, 68-72.
-
(2003)
Trends Genet.
, vol.19
, pp. 68-72
-
-
Jordan, I.K.1
Rogozin, I.B.2
Glazko, G.V.3
Koonin, E.V.4
-
14
-
-
33947303168
-
Transposable elements and the epigenetic regulation of the genome
-
Slotkin, R. K. and Martienssen, R. (2007) Transposable elements and the epigenetic regulation of the genome. Nat. Rev. Genet., 8, 272-285.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 272-285
-
-
Slotkin, R.K.1
Martienssen, R.2
-
15
-
-
0032756518
-
The establishment and maintenance of DNA methylation patterns in mouse somatic cells
-
Turker, M. S. (1999) The establishment and maintenance of DNA methylation patterns in mouse somatic cells. Semin. Cancer Biol., 9, 329-337.
-
(1999)
Semin. Cancer Biol.
, vol.9
, pp. 329-337
-
-
Turker, M.S.1
-
16
-
-
0033579468
-
Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylation
-
Yates, P. A., Burman, R. W., Mummaneni, P., Krussel, S. and Turker, M. S. (1999) Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylation. J. Biol. Chem., 274, 36357-36361.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36357-36361
-
-
Yates, P.A.1
Burman, R.W.2
Mummaneni, P.3
Krussel, S.4
Turker, M.S.5
-
17
-
-
0027525976
-
A cis-acting element accounts for a conserved methylation pattern upstream of the mouse adenine phosphoribosyltransferase gene
-
Mummaneni, P., Bishop, P. L. and Turker, M. S. (1993) A cis-acting element accounts for a conserved methylation pattern upstream of the mouse adenine phosphoribosyltransferase gene. J. Biol. Chem., 268, 552-558.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 552-558
-
-
Mummaneni, P.1
Bishop, P.L.2
Turker, M.S.3
-
18
-
-
0037706911
-
Silencing of mouse aprt is a gradual process in differentiated cells
-
Yates, P. A., Burman, R., Simpson, J., Ponomoreva, O. N., Thayer, M. J. and Turker, M. S. (2003) Silencing of mouse aprt is a gradual process in differentiated cells. Mol. Cell. Biol., 23, 4461-4470.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4461-4470
-
-
Yates, P.A.1
Burman, R.2
Simpson, J.3
Ponomoreva, O.N.4
Thayer, M.J.5
Turker, M.S.6
-
19
-
-
85047695221
-
Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells
-
Song, J. Z., Stirzaker, C., Harrison, J., Melki, J. R. and Clark, S. J. (2002) Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells. Oncogene, 21, 1048-1061.
-
(2002)
Oncogene
, vol.21
, pp. 1048-1061
-
-
Song, J.Z.1
Stirzaker, C.2
Harrison, J.3
Melki, J.R.4
Clark, S.J.5
-
20
-
-
0038678777
-
Sensitive and quantitative universal pyrosequencing methylation analysis of CpG sites
-
Colella, S., Shen, L., Baggerly, K. A., Issa, J. P. and Krahe, R. (2003) Sensitive and quantitative universal pyrosequencing methylation analysis of CpG sites. Biotechniques, 35, 146-150.
-
(2003)
Biotechniques
, vol.35
, pp. 146-150
-
-
Colella, S.1
Shen, L.2
Baggerly, K.A.3
Issa, J.P.4
Krahe, R.5
-
21
-
-
36849059066
-
LINE-1 Hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability
-
Estecio, M. R. H., Gharibyan, V., Shen, L., Ibrahim, A. E. K., Doshi, K., He, R., Jelinek, J., Yang, A. S., Yan, P. S., Huang, T. H. M. et al. (2007) LINE-1 Hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS One, 2, e399.
-
(2007)
PLoS One
, vol.2
-
-
Estecio, M.R.H.1
Gharibyan, V.2
Shen, L.3
Ibrahim, A.E.K.4
Doshi, K.5
He, R.6
Jelinek, J.7
Yang, A.S.8
Yan, P.S.9
Huang, T.H.M.10
-
22
-
-
62849122233
-
Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability
-
Richards, K. L., Zhang, B., Baggerly, K. A., Colella, S., Lang, J. C., Schuller, D. E. and Krahe, R. (2009) Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability. PLoS One, 4, e4941.
-
(2009)
PLoS One
, vol.4
-
-
Richards, K.L.1
Zhang, B.2
Baggerly, K.A.3
Colella, S.4
Lang, J.C.5
Schuller, D.E.6
Krahe, R.7
-
23
-
-
0034176798
-
DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
-
Baylin, S. B. and Herman, J. G. (2000) DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet., 16, 168-174.
-
(2000)
Trends Genet.
, vol.16
, pp. 168-174
-
-
Baylin, S.B.1
Herman, J.G.2
-
24
-
-
35948981875
-
Genome-wide profiling of DNA methylation reveals a class of normally methylated cpg island promoters
-
Shen, L., Kondo, Y., Guo, Y., Zhang, J., Zhang, L., Ahmed, S., Shu, J., Chen, X., Waterland, R. A. and Issa, J.-P. J. (2007) Genome-wide profiling of DNA methylation reveals a class of normally methylated cpg island promoters. PLoS Genet., 3, e181.
-
(2007)
PLoS Genet.
, vol.3
-
-
Shen, L.1
Kondo, Y.2
Guo, Y.3
Zhang, J.4
Zhang, L.5
Ahmed, S.6
Shu, J.7
Chen, X.8
Waterland, R.A.9
Issa, J.-P.J.10
-
25
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones, P. A. and Baylin, S. B. (2002) The fundamental role of epigenetic events in cancer. Nat. Rev. Genet., 3, 415-428.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
26
-
-
33947218451
-
RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis
-
Boumber, Y. A., Kondo, Y., Chen, X., Shen, L., Gharibyan, V., Konishi, K., Estey, E., Kantarjian, H., Garcia-Manero, G. and Issa, J.-P. J. (2007) RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Cancer Res., 67, 1997-2005.
-
(2007)
Cancer Res.
, vol.67
, pp. 1997-2005
-
-
Boumber, Y.A.1
Kondo, Y.2
Chen, X.3
Shen, L.4
Gharibyan, V.5
Konishi, K.6
Estey, E.7
Kantarjian, H.8
Garcia-Manero, G.9
Issa, J.-P.J.10
-
27
-
-
36249023071
-
A unified classification system for eukaryotic transposable elements
-
Wicker, T., Sabot, F., Hua-Van, A., Bennetzen, J. L., Capy, P., Chalhoub, B., Flavell, A., Leroy, P., Morgante, M., Panaud, O. et al. (2007) A unified classification system for eukaryotic transposable elements. Nat. Rev. Genet., 8, 973-982.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 973-982
-
-
Wicker, T.1
Sabot, F.2
Hua-Van, A.3
Bennetzen, J.L.4
Capy, P.5
Chalhoub, B.6
Flavell, A.7
Leroy, P.8
Morgante, M.9
Panaud, O.10
-
28
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird, A. (2002) DNA methylation patterns and epigenetic memory. Genes Dev., 16, 6-21.
-
(2002)
Genes Dev.
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
29
-
-
0842347353
-
Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation
-
Weisenberger, D. J., Velicescu, M., Cheng, J. C., Gonzales, F. A., Liang, G. N. and Jones, P. A. (2004) Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation. Mol. Cancer Res., 2, 62-72.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 62-72
-
-
Weisenberger, D.J.1
Velicescu, M.2
Cheng, J.C.3
Gonzales, F.A.4
Liang, G.N.5
Jones, P.A.6
-
30
-
-
77956320061
-
Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells
-
Athanasiadou, R., de Sousa, D., Myant, K., Merusi, C., Stancheva, I. and Bird, A. (2010) Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells. PLoS One, 5, e9937.
-
(2010)
PLoS One
, vol.5
-
-
Athanasiadou, R.1
Sousa, D.2
Myant, K.3
Merusi, C.4
Stancheva, I.5
Bird, A.6
-
31
-
-
80054994283
-
Identification of genetic elements that autonomously determine DNA methylation states
-
Lienert, F., Wirbelauer, C., Som, I., Dean, A., Mohn, F. and Schubeler, D. (2011) Identification of genetic elements that autonomously determine DNA methylation states. Nat. Genet., 43, 1091-1097.
-
(2011)
Nat. Genet.
, vol.43
, pp. 1091-1097
-
-
Lienert, F.1
Wirbelauer, C.2
Som, I.3
Dean, A.4
Mohn, F.5
Schubeler, D.6
-
32
-
-
68049104358
-
Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning
-
Hinshelwood, R. A., Melki, J. R., Huschtscha, L. I., Paul, C., Song, J. Z., Stirzaker, C., Reddel, R. R. and Clark, S. J. (2009) Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning. Hum. Mol. Genet., 18, 3098-3109.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3098-3109
-
-
Hinshelwood, R.A.1
Melki, J.R.2
Huschtscha, L.I.3
Paul, C.4
Song, J.Z.5
Stirzaker, C.6
Reddel, R.R.7
Clark, S.J.8
-
33
-
-
3042701155
-
Epigenomics: Beyond CpG islands
-
Fazzari, M. J. and Greally, J. M. (2004) Epigenomics: beyond CpG islands. Nat. Rev. Genet., 5, 446-455.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 446-455
-
-
Fazzari, M.J.1
Greally, J.M.2
-
34
-
-
42349096534
-
Transposable elements and the evolution of regulatory networks
-
Feschotte, C. (2008) Transposable elements and the evolution of regulatory networks. Nat. Rev. Genet., 9, 397-405.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 397-405
-
-
Feschotte, C.1
-
35
-
-
34447515727
-
Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis
-
Lunyak, V. V., Prefontaine, G. G., Nez, E., Cramer, T., Ju, B.-G., Ohgi, K. A., Hutt, K., Roy, R., Garcéa-Déaz, A., Zhu, X. et al. (2007) Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis. Science, 317, 248-251.
-
(2007)
Science
, vol.317
, pp. 248-251
-
-
Lunyak, V.V.1
Prefontaine, G.G.2
Nez, E.3
Cramer, T.4
Ju, B.-G.5
Ohgi, K.A.6
Hutt, K.7
Roy, R.8
Garcéa-Déaz, A.9
Zhu, X.10
-
36
-
-
78649274945
-
Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer
-
Estécio, M. R. H., Gallegos, J., Vallot, C., Castoro, R. J., Chung, W., Maegawa, S., Oki, Y., Kondo, Y., Jelinek, J., Shen, L. et al. (2010) Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res., 20, 1369-1382.
-
(2010)
Genome Res.
, vol.20
, pp. 1369-1382
-
-
Estécio, M.R.H.1
Gallegos, J.2
Vallot, C.3
Castoro, R.J.4
Chung, W.5
Maegawa, S.6
Oki, Y.7
Kondo, Y.8
Jelinek, J.9
Shen, L.10
-
37
-
-
0041624239
-
Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: A mammalian cell culture model of gene variegation
-
Ayyanathan, K., Lechner, M. S., Bell, P., Maul, G. G., Schultz, D. C., Yamada, Y., Tanaka, K., Torigoe, K. and Rauscher, F. J. (2003) Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation. Genes Dev., 17, 1855-1869.
-
(2003)
Genes Dev.
, vol.17
, pp. 1855-1869
-
-
Ayyanathan, K.1
Lechner, M.S.2
Bell, P.3
Maul, G.G.4
Schultz, D.C.5
Yamada, Y.6
Tanaka, K.7
Torigoe, K.8
Rauscher, F.J.9
-
38
-
-
0042626332
-
Heterochromatin: Stable and unstable invasions at home and abroad
-
Fahrner, J. A. and Baylin, S. B. (2003) Heterochromatin: stable and unstable invasions at home and abroad. Genes Dev., 17, 1805-1812.
-
(2003)
Genes Dev.
, vol.17
, pp. 1805-1812
-
-
Fahrner, J.A.1
Baylin, S.B.2
-
39
-
-
77649271805
-
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
-
Coolen, M. W., Stirzaker, C., Song, J. Z., Statham, A. L., Kassir, Z., Moreno, C. S., Young, A. N., Varma, V., Speed, T. P., Cowley, M. et al. (2010) Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity. Nat. Cell Biol., 12, 235-246.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 235-246
-
-
Coolen, M.W.1
Stirzaker, C.2
Song, J.Z.3
Statham, A.L.4
Kassir, Z.5
Moreno, C.S.6
Young, A.N.7
Varma, V.8
Speed, T.P.9
Cowley, M.10
|