메뉴 건너뛰기




Volumn 35, Issue 5, 2013, Pages 1961-1973

Role of epigenetics in human aging and longevity: Genome-wide DNA methylation profile in centenarians and centenarians' offspring

Author keywords

Aging; Centenarians' offspring; DNA methylation; Epigenetics; Longevity. Centenarians

Indexed keywords

ADOLESCENT; ADULT; AGED; AGING; AGPAT2 GENE; ALU SEQUENCE; ARTICLE; ATP13A4 GENE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DUSP22 GENE; ECRG4 GENE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIGENETICS; FEMALE; FLJ32569 GENE; GENE; GENE IDENTIFICATION; HUMAN; HUMAN CELL; ITALY; LEUKOCYTE; LIFE EXPECTANCY; LONGEVITY; MGC3207 GENE; NUCLEOTIDE METABOLISM; PYROSEQUENCING; SIGNAL TRANSDUCTION; SLC22A18 GENE; SLC38A4 GENE; STRUCTURED QUESTIONNAIRE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; VERY ELDERLY; ZNF169 GENE;

EID: 84890166425     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-012-9463-1     Document Type: Article
Times cited : (163)

References (33)
  • 1
    • 55349089210 scopus 로고    scopus 로고
    • Centenarian offspring: Start healthier and stay healthier
    • doi:10.1111/j.1532-5415.2008.01949.x
    • Adams ER, Nolan VG, Andersen SL, Perls TT, Terry DF (2008) Centenarian offspring: start healthier and stay healthier. J Am Geriatr Soc 56:2089-2092. doi:10.1111/j.1532-5415.2008.01949.x
    • (2008) J Am Geriatr Soc , vol.56 , pp. 2089-2092
    • Adams, E.R.1    Nolan, V.G.2    Andersen, S.L.3    Perls, T.T.4    Terry, D.F.5
  • 2
    • 0031215003 scopus 로고    scopus 로고
    • Hypoxia regulates basal and induced DNA synthesis and collagen type i production in human cardiac fibroblasts: Effects of transforming growth factor-β 1, thyroid hormone, angiotensin II and basic fibroblast growth factor
    • doi:10.1006/jmcc.1997.0462
    • Agocha A, Lee HW, Eghbali-Webb M (1997) Hypoxia regulates basal and induced DNA synthesis and collagen type I production in human cardiac fibroblasts: effects of transforming growth factor-β 1, thyroid hormone, angiotensin II and basic fibroblast growth factor. J Mol Cell Cardiol 29:2233-2244. doi:10.1006/jmcc.1997.0462
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 2233-2244
    • Agocha, A.1    Lee, H.W.2    Eghbali-Webb, M.3
  • 3
    • 77954672049 scopus 로고    scopus 로고
    • Ageassociated epigenetic modifications in human DNA increase its immunogenicity
    • Agrawal A, Tay J, Yang GE, Agrawal S, Gupta S (2010) Ageassociated epigenetic modifications in human DNA increase its immunogenicity. Aging 2:93-100
    • (2010) Aging , vol.2 , pp. 93-100
    • Agrawal, A.1    Tay, J.2    Yang, G.E.3    Agrawal, S.4    Gupta, S.5
  • 4
    • 33646080830 scopus 로고    scopus 로고
    • LINE-1 hypomethylation in a choline-deficiency-induced liver cancer in rats: Dependence on feeding period
    • doi:10.1155/JBB/2006/17142
    • Asada K, Kotake Y, Asada R, Saunders D, Broyles RH, Towner RA, Fukui H, Floyd RA (2006) LINE-1 hypomethylation in a choline-deficiency-induced liver cancer in rats: dependence on feeding period. J Biomed Biotechnol 1:17142. doi:10.1155/JBB/2006/17142
    • (2006) J Biomed Biotechnol , vol.1 , pp. 17142
    • Asada, K.1    Kotake, Y.2    Asada, R.3    Saunders, D.4    Broyles, R.H.5    Towner, R.A.6    Fukui, H.7    Floyd, R.A.8
  • 5
  • 6
    • 73249140409 scopus 로고    scopus 로고
    • Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity
    • doi:10.1210/jc.2009-0808
    • Atzmon G, Barzilai N, Surks MI, Gabriely I (2009b) Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity. J Clin Endocrinol Metab 94:4768-4775. doi:10.1210/jc.2009-0808
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4768-4775
    • Atzmon, G.1    Barzilai, N.2    Surks, M.I.3    Gabriely, I.4
  • 7
    • 0142052858 scopus 로고    scopus 로고
    • Insulin/IGFI-signaling pathway: An evolutionarily conserved mechanism of longevity from yeast to humans
    • doi:10.1152/ajpendo.00296.2003
    • Barbieri M, Bonafè M, Franceschi C, Paolisso G (2003) Insulin/IGFI-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am J Physiol Endocrinol Metab 285:1064-1071. doi:10.1152/ajpendo.00296.2003
    • (2003) Am J Physiol Endocrinol Metab , vol.285 , pp. 1064-1071
    • Barbieri, M.1    Bonafè, M.2    Franceschi, C.3    Paolisso, G.4
  • 11
    • 34548208677 scopus 로고    scopus 로고
    • Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
    • doi:10.1371/journal.pbio.0050201
    • Chambers SM, Shaw CA, Gatza C, Fisk CJ, Donehower LA, Goodell MA (2007) Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol 5:e201. doi:10.1371/journal.pbio.0050201
    • (2007) PLoS Biol , vol.5
    • Chambers, S.M.1    Shaw, C.A.2    Gatza, C.3    Fisk, C.J.4    Donehower, L.A.5    Goodell, M.A.6
  • 13
    • 60849139395 scopus 로고    scopus 로고
    • GOrilla: A tool for discovery and visualization of enriched GO terms in ranked gene lists
    • doi:10.1186/1471-2105-10-48
    • Eden E, Navon R, Steinfeld I, Lipson D, Yakhini Z (2009) GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists. BMC Bioinforma 10:48. doi:10.1186/1471-2105-10-48
    • (2009) BMC Bioinforma , vol.10 , pp. 48
    • Eden, E.1    Navon, R.2    Steinfeld, I.3    Lipson, D.4    Yakhini, Z.5
  • 15
    • 34249683635 scopus 로고    scopus 로고
    • Cross-talk between aging and cancer: The epigenetic language
    • doi:10.1196/annals.1395.005
    • Fraga MF, Agrelo R, Estell M (2007) Cross-talk between aging and cancer: the epigenetic language. Ann NY Acad Sci 1100:60-74. doi:10.1196/annals.1395.005
    • (2007) Ann NY Acad Sci , vol.1100 , pp. 60-74
    • Fraga, M.F.1    Agrelo, R.2    Estell, M.3
  • 16
    • 0037396614 scopus 로고    scopus 로고
    • Centenarians as amodel for healthy aging
    • doi:10.1042/BST0310457
    • Franceschi C, BonafèM(2003) Centenarians as amodel for healthy aging. Biochem Soc Trans 31:457-461. doi:10.1042/BST0310457
    • (2003) Biochem Soc Trans , vol.31 , pp. 457-461
    • Franceschi, C.1    Bonafè, M.2
  • 19
    • 9644257303 scopus 로고    scopus 로고
    • Thyroid status, disability and cognitive function, and survival in old age
    • doi:10.1001/jama.292.21.2591
    • Gussekloo J, van Exel E, de Craen AJ, Meinders AE, Frölich M (2004) Thyroid status, disability and cognitive function, and survival in old age. JAMA 292:2591-2599. doi:10.1001/jama.292.21.2591
    • (2004) JAMA , vol.292 , pp. 2591-2599
    • Gussekloo, J.1    Van Exel, E.2    De Craen, A.J.3    Meinders, A.E.4    Frölich, M.5
  • 20
    • 77953825565 scopus 로고    scopus 로고
    • DNA methylation as a biomarker for cardiovascular disease risk
    • doi:10.1371/journal.pone.0009692
    • Kim M, Long TI, Arakawa K, Wang R, Yu MC, Laird PW(2010) DNA methylation as a biomarker for cardiovascular disease risk. PLoS One 5:e9692. doi:10.1371/journal.pone.0009692
    • (2010) PLoS One , vol.5
    • Kim, M.1    Long, T.I.2    Arakawa, K.3    Wang, R.4    Yu, M.C.5    Laird, P.W.6
  • 21
    • 30744441925 scopus 로고    scopus 로고
    • Thyroid hormone induces cyclin D1 nuclear translocation and DNA synthesis in adult rat cardiomyocytes
    • doi:10.1096/fj.05-4202com
    • Ledda-Columbano GM, Molotzu F, Pibiri M, Cossu C, Perra A, Columbano A (2006) Thyroid hormone induces cyclin D1 nuclear translocation and DNA synthesis in adult rat cardiomyocytes. FASEB J 20:87-94. doi:10.1096/fj.05-4202com
    • (2006) FASEB J , vol.20 , pp. 87-94
    • Ledda-Columbano, G.M.1    Molotzu, F.2    Pibiri, M.3    Cossu, C.4    Perra, A.5    Columbano, A.6
  • 23
    • 33646937694 scopus 로고    scopus 로고
    • Thymic output and functionality of the IL-7/IL-7 receptor system in centenarians: Implications for the neolymphogenesis at the limit of human life
    • doi:10.1111/j.1474-9726.2006.00204.x
    • Nasi M, Troiano L, Lugli E, Pinti M, Ferraresi R, Monterastelli E, Mussi C, Salvioli G, Franceschi C, Cossarizza A (2006) Thymic output and functionality of the IL-7/IL-7 receptor system in centenarians: implications for the neolymphogenesis at the limit of human life. Aging Cell 5:167-175. doi:10.1111/j.1474-9726.2006.00204.x
    • (2006) Aging Cell , vol.5 , pp. 167-175
    • Nasi, M.1    Troiano, L.2    Lugli, E.3    Pinti, M.4    Ferraresi, R.5    Monterastelli, E.6    Mussi, C.7    Salvioli, G.8    Franceschi, C.9    Cossarizza, A.10
  • 24
    • 73249147909 scopus 로고    scopus 로고
    • Thyroid function and longevity: New insights into an Old Dilemma
    • doi:10.1210/jc.2009-2198
    • Peeters RP (2009) Thyroid function and longevity: new insights into an Old Dilemma. J Clin Endocrinol Metab 94:4658-4660. doi:10.1210/jc.2009-2198
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4658-4660
    • Peeters, R.P.1
  • 25
    • 77953469917 scopus 로고    scopus 로고
    • Epigenetics as a unifying principle in the aetiology of complex traits and diseases
    • doi:10.1038/nature09230
    • Petronis A (2010) Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 465:721-727. doi:10.1038/nature09230
    • (2010) Nature , vol.465 , pp. 721-727
    • Petronis, A.1
  • 27
    • 33747172229 scopus 로고    scopus 로고
    • Inflamm-aging, cytokines and aging: State of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology
    • doi:10.2174/138161206777947470
    • Salvioli S, Capri M, Valensin S, Tieri P, Monti D, Ottaviani E, Franceschi C (2006) Inflamm-aging, cytokines and aging: state of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology. Curr Pharm Des 12:3161-3171. doi:10.2174/138161206777947470
    • (2006) Curr Pharm des , vol.12 , pp. 3161-3171
    • Salvioli, S.1    Capri, M.2    Valensin, S.3    Tieri, P.4    Monti, D.5    Ottaviani, E.6    Franceschi, C.7
  • 29
    • 42149141146 scopus 로고    scopus 로고
    • Functionally significant insulin-like growth factor i receptor mutations in centenarians
    • doi:10.1073/pnas.0705467105
    • Suh Y, Atzmon G, Cho MO, Hwang D, Liu B, Leahy DJ, Barzilai N, Cohen P (2008) Functionally significant insulin-like growth factor I receptor mutations in centenarians. PNAS 105:3438-3442. doi:10.1073/pnas.0705467105
    • (2008) PNAS , vol.105 , pp. 3438-3442
    • Suh, Y.1    Atzmon, G.2    Cho, M.O.3    Hwang, D.4    Liu, B.5    Leahy, D.J.6    Barzilai, N.7    Cohen, P.8
  • 30
    • 0037133565 scopus 로고    scopus 로고
    • Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    • doi:10.1073/pnas.052410099
    • Takai D, Jones PA (2002) Comprehensive analysis of CpG islands in human chromosomes 21 and 22. PNAS 99:3740-3745. doi:10.1073/pnas.052410099
    • (2002) PNAS , vol.99 , pp. 3740-3745
    • Takai, D.1    Jones, P.A.2
  • 32
    • 28744449007 scopus 로고    scopus 로고
    • Thyroid hormone concentrations, disease, physical function, and mortality in elderly men
    • doi:10.1210/jc.2005-0872
    • Van den Beld AW, Visser TJ, Feelders RA, Grobbee DE, Lamberts SW (2005) Thyroid hormone concentrations, disease, physical function, and mortality in elderly men. J Clin Endocrinol Metab 90:6403-6409. doi:10.1210/jc.2005-0872
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 6403-6409
    • Van Den Beld, A.W.1    Visser, T.J.2    Feelders, R.A.3    Grobbee, D.E.4    Lamberts, S.W.5
  • 33
    • 33845332711 scopus 로고    scopus 로고
    • DNA hypomethylation and human diseases
    • doi:10.1016/j.bbcan.2006.08.007
    • Wilson AS, Power BE, Molloy PL (2007) DNA hypomethylation and human diseases. Biochim Biophys Acta 1775:138-162. doi:10.1016/j.bbcan.2006.08.007
    • (2007) Biochim Biophys Acta , vol.1775 , pp. 138-162
    • Wilson, A.S.1    Power, B.E.2    Molloy, P.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.