The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner

Aging Cell

Volumn 10, Issue 6, 2011, Pages 980-990

  Maures, Travis J ^a   Greer, Eric L ^a   Hauswirth, Anna G ^a   Brunet, Anne ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Aging; Caenorhabditis elegans; Epigenetic; FoxO transcription factor; Germline; H3K27me3; Histone demethylase; Insulin pathway; Lifespan; Soma; UTX

Indexed keywords

HISTONE DEMETHYLASE; LSD 1 ENZYME; RBR 2 ENZYME; T26A5.5 ENZYME; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; UTX 1 ENZYME;

ARTICLE; CAENORHABDITIS ELEGANS; ENZYME ACTIVITY; GERMLINE MICRONUCLEUS; LIFESPAN; LONGEVITY; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SOMATIC CELL;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CAENORHABDITIS ELEGANS; CHROMATIN; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GERM CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HISTONE DEMETHYLASES; HISTONES; INSULIN; LONGEVITY; METHYLATION; POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

CAENORHABDITIS ELEGANS;

EID: 81155139577     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00738.x     Document Type: Article

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