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Volumn 120, Issue 4, 2005, Pages 523-532

Genetic modulation of senescent phenotypes in Homo sapiens

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; HELICASE;

EID: 13944280713     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2005.01.031     Document Type: Review
Times cited : (146)

References (88)
  • 1
    • 4444261794 scopus 로고    scopus 로고
    • Seipin: A mysterious protein
    • A.K. Agarwal, and A. Garg Seipin: a mysterious protein Trends Mol. Med. 10 2004 440 444
    • (2004) Trends Mol. Med. , vol.10 , pp. 440-444
    • Agarwal, A.K.1    Garg, A.2
  • 7
    • 4043132373 scopus 로고    scopus 로고
    • The current status of Alzheimer's disease genetics: What do we tell the patients?
    • L. Bertram, and R.E. Tanzi The current status of Alzheimer's disease genetics: what do we tell the patients? Pharmacol. Res. 50 2004 385 396
    • (2004) Pharmacol. Res. , vol.50 , pp. 385-396
    • Bertram, L.1    Tanzi, R.E.2
  • 8
    • 3843066722 scopus 로고    scopus 로고
    • Unraveling the pathogenesis of Parkinson's disease - The contribution of monogenic forms
    • V. Bonifati, B.A. Oostra, and P. Heutink Unraveling the pathogenesis of Parkinson's disease - the contribution of monogenic forms Cell. Mol. Life Sci. 61 2004 1729 1750
    • (2004) Cell. Mol. Life Sci. , vol.61 , pp. 1729-1750
    • Bonifati, V.1    Oostra, B.A.2    Heutink, P.3
  • 10
    • 0013321009 scopus 로고
    • Familial hypercholesterolemia: Defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3- methylglutaryl coenzyme a reductase activity
    • M.S. Brown, and J.L. Goldstein Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity Proc. Natl. Acad. Sci. USA 71 1974 788 792
    • (1974) Proc. Natl. Acad. Sci. USA , vol.71 , pp. 788-792
    • Brown, M.S.1    Goldstein, J.L.2
  • 12
    • 5344271854 scopus 로고    scopus 로고
    • Memory and executive function in aging and AD; Multiple factors that cause decline and reserve factors that compensate
    • R.L. Buckner Memory and executive function in aging and AD; multiple factors that cause decline and reserve factors that compensate Neuron 44 2004 195 208
    • (2004) Neuron , vol.44 , pp. 195-208
    • Buckner, R.L.1
  • 13
    • 2642582435 scopus 로고    scopus 로고
    • Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation
    • X. Cao, and T.C. Sudhof Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation J. Biol. Chem. 279 2004 24601 24611
    • (2004) J. Biol. Chem. , vol.279 , pp. 24601-24611
    • Cao, X.1    Sudhof, T.C.2
  • 19
    • 3242668604 scopus 로고    scopus 로고
    • Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
    • P.E. Coskun, M.F. Beal, and D.C. Wallace Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication Proc. Natl. Acad. Sci. USA 101 2004 10726 10731
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 10726-10731
    • Coskun, P.E.1    Beal, M.F.2    Wallace, D.C.3
  • 20
    • 10344256183 scopus 로고    scopus 로고
    • Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
    • L. Crabbe, R.E. Verdun, C.I. Haggblom, and J. Karlseder Defective telomere lagging strand synthesis in cells lacking WRN helicase activity Science 306 2004 1951 1953
    • (2004) Science , vol.306 , pp. 1951-1953
    • Crabbe, L.1    Verdun, R.E.2    Haggblom, C.I.3    Karlseder, J.4
  • 21
    • 1642267429 scopus 로고    scopus 로고
    • Correlation of cochlear blood supply with mitochondrial DNA common deletion in presbyacusis
    • P. Dai, W. Yang, S. Jiang, R. Gu, H. Yuan, D. Han, W. Guo, and J. Cao Correlation of cochlear blood supply with mitochondrial DNA common deletion in presbyacusis Acta Otolaryngol. 124 2004 130 136
    • (2004) Acta Otolaryngol. , vol.124 , pp. 130-136
    • Dai, P.1    Yang, W.2    Jiang, S.3    Gu, R.4    Yuan, H.5    Han, D.6    Guo, W.7    Cao, J.8
  • 22
    • 0015319601 scopus 로고
    • The Hutchinson-Gilford progeria syndrome. Report of 4 cases and review of the literature
    • F.L. DeBusk The Hutchinson-Gilford progeria syndrome. Report of 4 cases and review of the literature J. Pediatr. 80 1972 697 724
    • (1972) J. Pediatr. , vol.80 , pp. 697-724
    • Debusk, F.L.1
  • 24
    • 3242892589 scopus 로고    scopus 로고
    • Nijmegen breakage syndrome: Clinical manifestation of defective response to DNA double-strand breaks
    • M. Digweed, and K. Sperling Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks DNA Repair (Amst.) 3 2004 1207 1217
    • (2004) DNA Repair (Amst.) , vol.3 , pp. 1207-1217
    • Digweed, M.1    Sperling, K.2
  • 25
    • 1842614985 scopus 로고    scopus 로고
    • Slow progression of ataxia-telangiectasia with double missense and in frame splice mutations
    • T. Dork, R.D. Wegner, and M. Stumm Slow progression of ataxia-telangiectasia with double missense and in frame splice mutations Am. J. Med. Genet. 126A 2004 272 277
    • (2004) Am. J. Med. Genet. , vol.126 , pp. 272-277
    • Dork, T.1    Wegner, R.D.2    Stumm, M.3
  • 27
    • 0014279781 scopus 로고
    • Variation of atherosclerosis with age
    • D.A. Eggen, and L.A. Solberg Variation of atherosclerosis with age Lab. Invest. 18 1968 571 579
    • (1968) Lab. Invest. , vol.18 , pp. 571-579
    • Eggen, D.A.1    Solberg, L.A.2
  • 30
    • 0033808703 scopus 로고    scopus 로고
    • Homoplasmic mitochondrial DNA diseases as the paradigm to understand the tissue specificity and variable clinical severity of mitochondrial disorders
    • N. Fischel-Ghodsian Homoplasmic mitochondrial DNA diseases as the paradigm to understand the tissue specificity and variable clinical severity of mitochondrial disorders Mol. Genet. Metab. 71 2000 93 99
    • (2000) Mol. Genet. Metab. , vol.71 , pp. 93-99
    • Fischel-Ghodsian, N.1
  • 31
    • 7044238416 scopus 로고    scopus 로고
    • Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
    • M.S. Forman, J.Q. Trojanowski, and V.M. Lee Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs Nat. Med. 10 2004 1055 1063
    • (2004) Nat. Med. , vol.10 , pp. 1055-1063
    • Forman, M.S.1    Trojanowski, J.Q.2    Lee, V.M.3
  • 32
    • 0005073263 scopus 로고    scopus 로고
    • Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein
    • J.E. Garbarino, and I.R. Gibbons Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein BMC Genomics 3 2002 18
    • (2002) BMC Genomics , vol.3 , pp. 18
    • Garbarino, J.E.1    Gibbons, I.R.2
  • 37
    • 13944250151 scopus 로고    scopus 로고
    • Genetic Instability and Fanconi Syndrome
    • F.M. Hisami S.M. Weissman G.M. Martin Marcel Dekker New York
    • H. Hoehn, M. Gross, D. Schindler, A. Sobeck, and M. Wagner Genetic Instability and Fanconi Syndrome F.M. Hisami S.M. Weissman G.M. Martin Chromosomal Instability and Aging. 2003 Marcel Dekker New York 375 408
    • (2003) Chromosomal Instability and Aging. , pp. 375-408
    • Hoehn, H.1    Gross, M.2    Schindler, D.3    Sobeck, A.4    Wagner, M.5
  • 39
    • 13944256088 scopus 로고    scopus 로고
    • Bloom Syndrome: Genetic, cellular, and molecular features as compared to Werner syndrome
    • F.M. Hisami S.M. Weissman G.M. Martin Marcel Dekker New York
    • P. Hu, and N.A. Ellis Bloom Syndrome: Genetic, cellular, and molecular features as compared to Werner syndrome F.M. Hisami S.M. Weissman G.M. Martin Chromosomal Instability and Aging 2004 Marcel Dekker New York 187 222
    • (2004) Chromosomal Instability and Aging , pp. 187-222
    • Hu, P.1    Ellis, N.A.2
  • 40
    • 9144228044 scopus 로고    scopus 로고
    • Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration
    • S.K. Iyengar, D. Song, B.E. Klein, R. Klein, J.H. Schick, J. Humphrey, C. Millard, R. Liptak, K. Russo, and G. Jun Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration Am. J. Hum. Genet. 74 2004 20 39
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 20-39
    • Iyengar, S.K.1    Song, D.2    Klein, B.E.3    Klein, R.4    Schick, J.H.5    Humphrey, J.6    Millard, C.7    Liptak, R.8    Russo, K.9    Jun, G.10
  • 43
    • 0037162533 scopus 로고    scopus 로고
    • The emergence of humans: The coevolution of intelligence and longevity with intergenerational transfers
    • H.S. Kaplan, and A.J. Robson The emergence of humans: the coevolution of intelligence and longevity with intergenerational transfers Proc. Natl. Acad. Sci. USA 99 2002 10221 10226
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10221-10226
    • Kaplan, H.S.1    Robson, A.J.2
  • 44
    • 1642396519 scopus 로고    scopus 로고
    • Enhanced stem cell survival in familial adenomatous polyposis
    • K.M. Kim, P. Calabrese, S. Tavare, and D. Shibata Enhanced stem cell survival in familial adenomatous polyposis Am. J. Pathol. 164 2004 1369 1377
    • (2004) Am. J. Pathol. , vol.164 , pp. 1369-1377
    • Kim, K.M.1    Calabrese, P.2    Tavare, S.3    Shibata, D.4
  • 45
    • 85056966423 scopus 로고    scopus 로고
    • Molecular biology of Rothmund-Thomson Syndrome
    • F. Hisami S.M. Weissman G.M. Martin Marcel Dekker New York
    • S. Kitao, A. Shimamoto, and Y. Furuichi Molecular biology of Rothmund-Thomson Syndrome F. Hisami S.M. Weissman G.M. Martin Chromosomal Instability and Aging 2003 Marcel Dekker New York 223 244
    • (2003) Chromosomal Instability and Aging , pp. 223-244
    • Kitao, S.1    Shimamoto, A.2    Furuichi, Y.3
  • 46
    • 0742306066 scopus 로고    scopus 로고
    • Mutant genes responsible for Parkinson's disease
    • W. Le, and S.H. Appel Mutant genes responsible for Parkinson's disease Curr. Opin. Pharmacol. 4 2004 79 84
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 79-84
    • Le, W.1    Appel, S.H.2
  • 47
    • 0042631525 scopus 로고    scopus 로고
    • Rethinking the evolutionary theory of aging: Transfers, not senescence in social species
    • R.D. Lee Rethinking the evolutionary theory of aging: transfers, not senescence in social species Proc. Natl. Acad. Sci. USA 100 2003 9637 9642
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9637-9642
    • Lee, R.D.1
  • 48
    • 0942268166 scopus 로고    scopus 로고
    • DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy
    • A.R. Lehmann DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy Biochimie 85 2003 1101 1111
    • (2003) Biochimie , vol.85 , pp. 1101-1111
    • Lehmann, A.R.1
  • 51
    • 0017840139 scopus 로고
    • Genetic syndromes in man with potential relevance to the pathobiology of aging
    • G.M. Martin Genetic syndromes in man with potential relevance to the pathobiology of aging Birth Defects Orig. Artic. Ser. 14 1978 5 39
    • (1978) Birth Defects Orig. Artic. Ser. , vol.14 , pp. 5-39
    • Martin, G.M.1
  • 52
    • 10044233941 scopus 로고    scopus 로고
    • Help wanted: Physiologists for research on aging
    • G.M. Martin Help wanted: physiologists for research on aging Sci. Aging Knowledge Environ. 9 2002 vp2
    • (2002) Sci. Aging Knowledge Environ. , vol.9 , pp. 2
    • Martin, G.M.1
  • 53
    • 0036845599 scopus 로고    scopus 로고
    • The evolutionary substrate of aging
    • G.M. Martin The evolutionary substrate of aging Arch. Neurol. 59 2002 1702 1705
    • (2002) Arch. Neurol. , vol.59 , pp. 1702-1705
    • Martin, G.M.1
  • 55
    • 0015521323 scopus 로고
    • Clonal senescence and atherosclerosis
    • G.M. Martin, and C.A. Sprague Clonal senescence and atherosclerosis Lancet 2 1972 1370 1371
    • (1972) Lancet , vol.2 , pp. 1370-1371
    • Martin, G.M.1    Sprague, C.A.2
  • 56
    • 13944279784 scopus 로고    scopus 로고
    • Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary Parkinsonism
    • 10.1371/journal.pbio.0020327
    • C. Martinat, S. Shendelman, A. Jonason, T. Leete, M.F. Beal, L. Yang, T. Floss, and A. Abeliovich Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary Parkinsonism PLoS Biol. 2 2004 e327 10.1371/journal.pbio.0020327
    • (2004) PLoS Biol. , vol.2 , pp. 327
    • Martinat, C.1    Shendelman, S.2    Jonason, A.3    Leete, T.4    Beal, M.F.5    Yang, L.6    Floss, T.7    Abeliovich, A.8
  • 57
    • 4444339751 scopus 로고    scopus 로고
    • ATM and ataxia telangiectasia
    • P.J. McKinnon ATM and ataxia telangiectasia EMBO Rep. 5 2004 772 776
    • (2004) EMBO Rep. , vol.5 , pp. 772-776
    • McKinnon, P.J.1
  • 58
    • 13944283557 scopus 로고    scopus 로고
    • Ataxia-Telangiectasia
    • F.M. Hisami S.M. Weissman G.M. Martin Marcel Dekker, Inc. New York
    • M.S. Meys Ataxia-Telangiectasia F.M. Hisami S.M. Weissman G.M. Martin Chromosomal Instability and Aging 2003 Marcel Dekker, Inc. New York 263 309
    • (2003) Chromosomal Instability and Aging , pp. 263-309
    • Meys, M.S.1
  • 59
    • 4344706812 scopus 로고    scopus 로고
    • Werner syndrome protein-unwinding function to explain disease
    • R.J. Monnat Jr., and Y. Saintigny Werner syndrome protein-unwinding function to explain disease Sci. Aging Knowledge Environ. 13 2004 re3
    • (2004) Sci. Aging Knowledge Environ. , vol.13 , pp. 3
    • Monnat Jr., R.J.1    Saintigny, Y.2
  • 60
    • 8444236025 scopus 로고    scopus 로고
    • The adenomatous polyposis coli protein: The Achilles heel of the gut epithelium
    • I.S. Nathke The adenomatous polyposis coli protein: The Achilles heel of the gut epithelium Annu. Rev. Cell Dev. Biol. 20 2004 337 366
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 337-366
    • Nathke, I.S.1
  • 62
    • 0037081095 scopus 로고    scopus 로고
    • Lack of WRN results in extensive deletion at nonhomologous joining ends
    • J. Oshima, S. Huang, C. Pae, J. Campisi, and R.H. Schiestl Lack of WRN results in extensive deletion at nonhomologous joining ends Cancer Res. 62 2002 547 551
    • (2002) Cancer Res. , vol.62 , pp. 547-551
    • Oshima, J.1    Huang, S.2    Pae, C.3    Campisi, J.4    Schiestl, R.H.5
  • 63
    • 9144263052 scopus 로고    scopus 로고
    • The G115S mutation associated to maturity onset diabetes of the young impairs hepatocyte nuclear factor 4alpha activities and introduces a PKA phosphorylation site in its DNA binding domain
    • B. Oxombre, M. Kouach, E. Moerman, P. Formstecher, and B. Laine The G115S mutation associated to maturity onset diabetes of the young impairs hepatocyte nuclear factor 4alpha activities and introduces a PKA phosphorylation site in its DNA binding domain Biochem. J. 383 2004 573 580
    • (2004) Biochem. J. , vol.383 , pp. 573-580
    • Oxombre, B.1    Kouach, M.2    Moerman, E.3    Formstecher, P.4    Laine, B.5
  • 64
    • 0036245337 scopus 로고    scopus 로고
    • Mechanisms of ageing: Public or private?
    • L. Partridge, and D. Gems Mechanisms of ageing: public or private? Nat. Rev. Genet. 3 2002 165 175
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 165-175
    • Partridge, L.1    Gems, D.2
  • 66
    • 2342461060 scopus 로고    scopus 로고
    • Myotonic dystrophy: RNA pathogenesis comes into focus
    • L.P. Ranum, and J.W. Day Myotonic dystrophy: RNA pathogenesis comes into focus Am. J. Hum. Genet. 74 2004 793 804
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 793-804
    • Ranum, L.P.1    Day, J.W.2
  • 68
    • 4544339736 scopus 로고    scopus 로고
    • Replication protein a and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks
    • J.G. Robison, J. Elliott, K. Dixon, and G.G. Oakley Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks J. Biol. Chem. 279 2004 34802 34810
    • (2004) J. Biol. Chem. , vol.279 , pp. 34802-34810
    • Robison, J.G.1    Elliott, J.2    Dixon, K.3    Oakley, G.G.4
  • 69
    • 0019440557 scopus 로고
    • Cytogenetics of Werner's syndrome cultured skin fibroblasts: Variegated translocation mosaicism
    • D. Salk, K. Au, H. Hoehn, and G.M. Martin Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism Cytogenet. Cell Genet. 30 1981 92 107
    • (1981) Cytogenet. Cell Genet. , vol.30 , pp. 92-107
    • Salk, D.1    Au, K.2    Hoehn, H.3    Martin, G.M.4
  • 70
    • 0019449447 scopus 로고
    • Evidence of clonal attenuation, clonal succession, and clonal expansion in mass cultures of aging Werner's syndrome skin fibroblasts
    • D. Salk, K. Au, H. Hoehn, M.R. Stenchever, and G.M. Martin Evidence of clonal attenuation, clonal succession, and clonal expansion in mass cultures of aging Werner's syndrome skin fibroblasts Cytogenet. Cell Genet. 30 1981 108 117
    • (1981) Cytogenet. Cell Genet. , vol.30 , pp. 108-117
    • Salk, D.1    Au, K.2    Hoehn, H.3    Stenchever, M.R.4    Martin, G.M.5
  • 71
    • 0000242094 scopus 로고
    • Generalized lipodystrophy. 1
    • M. Seip, and O. Trygstad Generalized lipodystrophy. 1 Arch. Dis. Child. 38 1963 447 453
    • (1963) Arch. Dis. Child. , vol.38 , pp. 447-453
    • Seip, M.1    Trygstad, O.2
  • 72
    • 9444297972 scopus 로고    scopus 로고
    • Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1
    • L. Shahrabani-Gargir, T.K. Pandita, and H. Werner Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1 Endocrinology 145 2004 5679 5687
    • (2004) Endocrinology , vol.145 , pp. 5679-5687
    • Shahrabani-Gargir, L.1    Pandita, T.K.2    Werner, H.3
  • 73
    • 5444272914 scopus 로고    scopus 로고
    • In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication
    • S. Sharma, J.A. Sommers, and R.M. Brosh Jr. In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication Hum. Mol. Genet. 13 2004 2247 2261
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2247-2261
    • Sharma, S.1    Sommers, J.A.2    Brosh Jr., R.M.3
  • 74
    • 4043079949 scopus 로고    scopus 로고
    • Mitochondria and dopamine; New insights into recessive parkinsonism
    • J. Shen, and M.R. Cookson Mitochondria and dopamine; new insights into recessive parkinsonism Neuron 43 2004 301 304
    • (2004) Neuron , vol.43 , pp. 301-304
    • Shen, J.1    Cookson, M.R.2
  • 76
    • 13944267769 scopus 로고    scopus 로고
    • DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation
    • DOI:10.1371/journal.pbio.0020362.
    • Shendelman, S., Jonason, A., Martinat, C., Leete, T., and Abeliovich, A. (2004). DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation. PLoS Biol. 2 (11): e362 DOI:10.1371/journal.pbio.0020362.
    • (2004) PLoS Biol. , vol.2 , Issue.11
    • Shendelman, S.1    Jonason, A.2    Martinat, C.3    Leete, T.4    Abeliovich, A.5
  • 81
    • 6344235765 scopus 로고    scopus 로고
    • A powerful and robust new linkage statistic for discordant sibling pairs
    • J.P. Szatkiewicz, and E. Feingold A powerful and robust new linkage statistic for discordant sibling pairs Am. J. Hum. Genet. 75 2004 906 909
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 906-909
    • Szatkiewicz, J.P.1    Feingold, E.2
  • 82
    • 0026148606 scopus 로고
    • Werner's syndrome combined with quintuplicate malignant tumors: A case report and review of literature data
    • H. Tsuchiya, K. Tomita, M. Ohno, M. Inaoki, and A. Kawashima Werner's syndrome combined with quintuplicate malignant tumors: a case report and review of literature data Jpn. J. Clin. Oncol. 21 1991 135 142
    • (1991) Jpn. J. Clin. Oncol. , vol.21 , pp. 135-142
    • Tsuchiya, H.1    Tomita, K.2    Ohno, M.3    Inaoki, M.4    Kawashima, A.5
  • 83
    • 0347995021 scopus 로고    scopus 로고
    • APC haploinsufficiency, but not CTNNB1 or CDH1 gene mutations, accounts for a fraction of familial adenomatous polyposis patients without APC truncating mutations
    • T. Venesio, A. Balsamo, M. Rondo-Spaudo, L. Varesco, M. Risio, and G.N. Ranzani APC haploinsufficiency, but not CTNNB1 or CDH1 gene mutations, accounts for a fraction of familial adenomatous polyposis patients without APC truncating mutations Lab. Invest. 83 2003 1859 1866
    • (2003) Lab. Invest. , vol.83 , pp. 1859-1866
    • Venesio, T.1    Balsamo, A.2    Rondo-Spaudo, M.3    Varesco, L.4    Risio, M.5    Ranzani, G.N.6
  • 84
    • 3142523288 scopus 로고    scopus 로고
    • Genetic clues to the pathogenesis of Parkinson's disease
    • M. Vila, and S. Przedborski Genetic clues to the pathogenesis of Parkinson's disease Nat. Med. 10 2004 S58 S62
    • (2004) Nat. Med. , vol.10
    • Vila, M.1    Przedborski, S.2
  • 85
    • 3242695252 scopus 로고    scopus 로고
    • Genes, proteins, and neurotoxins involved in Parkinson's disease
    • H.O. Von Bohlen Und, A. Schober, and K. Krieglstein Genes, proteins, and neurotoxins involved in Parkinson's disease Prog. Neurobiol. 73 2004 151 177
    • (2004) Prog. Neurobiol. , vol.73 , pp. 151-177
    • Von Bohlen Und, H.O.1    Schober, A.2    Krieglstein, K.3
  • 86
    • 85047692354 scopus 로고    scopus 로고
    • How do mutations in lamins a and C cause disease?
    • H.J. Worman, and J.C. Courvalin How do mutations in lamins A and C cause disease? J. Clin. Invest. 113 2004 349 351
    • (2004) J. Clin. Invest. , vol.113 , pp. 349-351
    • Worman, H.J.1    Courvalin, J.C.2
  • 87
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • L. Wu, and I.D. Hickson The Bloom's syndrome helicase suppresses crossing over during homologous recombination Nature 426 2003 870 874
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1    Hickson, I.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.