Bioprocess engineering aspects of heterologous protein production in Pichia pastoris: A review

Biochemical Engineering Journal

Volumn 64, Issue , 2012, Pages 91-105

  Potvin, Gabriel ^a   Ahmad, Ayla ^a   Zhang, Zisheng ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Continuous cultivation; Fed batch cultivation; Fermentation; Pichia pastoris; Process modeling; Proteolytic degradation

Indexed keywords

CONTINUOUS CULTIVATION; FED-BATCH CULTIVATION; PICHIA PASTORIS; PROCESS MODELING; PROTEOLYTIC DEGRADATION;

BIOCHEMICAL ENGINEERING; DEGRADATION; FERMENTATION; METHANOL; YEAST;

PROTEINS;

ALCOHOL OXIDASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; METHANOL; PHYTASE; PROTEINASE; PROTEINASE INHIBITOR;

BIOMASS; BIOPROCESS; CELL GROWTH; CONTINUOUS CULTURE; COST BENEFIT ANALYSIS; CULTURE MEDIUM; DISSOLVED OXYGEN STAT CONTROL; ENZYME ACTIVITY; ENZYME SYNTHESIS; FED BATCH CULTURE; FED BATCH SHAKE FLASK CULTURE; GENE EXPRESSION SYSTEM; HETEROLOGOUS EXPRESSION; MU STAT CONTROL; NONHUMAN; OXYGEN LIMITED FED BATCH; PH; PICHIA PASTORIS; PRIORITY JOURNAL; PROCESS CONTROL; PROCESS MONITORING; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN STABILITY; REVIEW; SPECIES CULTIVATION; TEMPERATURE; TEMPERATURE LIMITED FED BATCH; YEAST;

PICHIA PASTORIS;

EID: 84859829953     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2010.07.017     Document Type: Review

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