A simple model-based control for Pichia pastoris allows a more efficient heterologous protein production bioprocess

Biotechnology and Bioengineering

Volumn 95, Issue 1, 2006, Pages 145-154

  Cos, Oriol ^a   Ramon, Ramon ^a   Montesinos, José Luis ^a   Valero, Francisco ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Fed batch; Heterologous lipase production; Methanol monitoring; Model based control; Pichia pastoris

Indexed keywords

ALGORITHMS; BIOMASS; FEEDBACK CONTROL; INDUSTRIAL APPLICATIONS; METHANOL; PROTEINS; ROBUSTNESS (CONTROL SYSTEMS);

FED-BATCH; HETEROLOGOUS LIPASE PRODUCTION; METHANOL MONITORING; MODEL-BASED CONTROL; PICHIA PASTORIS;

PREDICTIVE CONTROL SYSTEMS;

METHANOL; TRIACYLGLYCEROL LIPASE;

ALGORITHM; ANIMAL CELL; ARTICLE; BIOMASS; BIOPROCESS; FERMENTATION; LIPOLYSIS; NONHUMAN; PHENOTYPE; PICHIA PASTORIS; PRODUCTIVITY; PROTEIN PROCESSING; RHIZOPUS ORYZAE;

BIOREACTORS; COMPUTER SIMULATION; FEEDBACK; LIPASE; METHANOL; MODELS, BIOLOGICAL; PICHIA; RECOMBINANT PROTEINS; RHIZOPUS;

PICHIA PASTORIS; RHIZOPUS ORYZAE;

EID: 33748425718     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21005     Document Type: Article

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