Monitoring a high cell density recombinant Pichia pastoris fed-batch bioprocess using transmission and reflectance near infrared spectroscopy

Enzyme and Microbial Technology

Volumn 36, Issue 5-6, 2005, Pages 621-628

  Crowley, John ^a,d   Arnold, S Alison ^a,c   Wood, Nigel ^b   Harvey, Linda M ^a   McNeil, Brian ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b British Biotechnology   (United Kingdom)

^c Joseph Black Building ^*  (United Kingdom)

^d DSM RESOLVE   (Netherlands)

Author keywords

High cell density; Model; NIRS; Pichia pastoris

Indexed keywords

BIOMASS; FERMENTATION; GLYCEROL; GROWTH KINETICS; METHANOL; PROTEINS;

BIOPROCESSES; NEAR INFRARED SPECTROSCOPY (NIRS); PICHIA PASTORIS; SPECTRAL COLLECTION;

CELLS;

CARBON; GLYCEROL; METHANOL; RECOMBINANT PROTEIN;

ARTICLE; BIOMASS; BIOPROCESS; CELL DENSITY; CELL GROWTH; CONCENTRATION (PARAMETERS); FED BATCH CULTURE; INDUSTRIAL PRODUCTION; MAMMAL; MATHEMATICAL COMPUTING; MONITORING; NEAR INFRARED SPECTROSCOPY; NONHUMAN; PICHIA PASTORIS; TECHNOLOGY;

MAMMALIA; PICHIA PASTORIS;

EID: 14544297416     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2003.12.016     Document Type: Article

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