Effective and stable porcine interferon-α production by pichia pastoris fed-batch cultivation with multi-variables clustering and analysis

Bioprocess and Biosystems Engineering

Volumn 33, Issue 4, 2010, Pages 473-483

  Yu, Ruisong ^a   Dong, Shijuan ^a   Zhu, Yumin ^a   Jin, Hu ^b   Gao, Mingjie ^b   Duan, Zuoying ^b   Zheng, Zhiyong ^b   Shi, Zhongping ^b   Li, Zhen ^a  

^a INSTITUTE OF EDIBLE FUNGI   (China)

^b JIANGNAN UNIVERSITY   (China)

Author keywords

Expression; Fed batch culture; Multi variables clustering; Oxygen uptake rate (OUR); Pichia pastoris; Porcine interferon

Indexed keywords

ANALYSIS RESULTS; ANTIVIRAL ACTIVITIES; CONSUMPTION RATES; FED-BATCH CULTIVATION; FED-BATCH CULTURES; HIGH DENSITY; MULTI VARIABLES; OXYGEN UPTAKE RATES; PICHIA PASTORIS; PRODUCTION EFFICIENCY; SHAKING FLASKS;

ANTIBIOTICS; BATCH CELL CULTURE; BIOREACTORS; BOTTLES; GLYCEROL; GLYCOPROTEINS; METHANOL; OXYGEN;

CLUSTER ANALYSIS;

ALPHA INTERFERON; GLYCEROL; METHANOL;

ANIMAL TISSUE; ARTICLE; BIOREACTOR; CONTROLLED STUDY; DRUG ACTIVITY; FED BATCH CULTURE; FED BATCH FERMENTATION; FUNGUS GROWTH; NONHUMAN; OXYGEN CONSUMPTION; PICHIA PASTORIS; PRIORITY JOURNAL; SWINE;

ANIMALS; ANTIVIRAL AGENTS; BIOENGINEERING; BIOREACTORS; CLUSTER ANALYSIS; FERMENTATION; GLYCEROL; INTERFERON TYPE I, RECOMBINANT; KINETICS; METHANOL; OXYGEN CONSUMPTION; PICHIA; SWINE;

PICHIA PASTORIS; SUS;

EID: 77953612696     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-009-0356-3     Document Type: Article

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