Engineering of protein secretion in yeast: Strategies and impact on protein production

Applied Microbiology and Biotechnology

Volumn 86, Issue 2, 2010, Pages 403-417

  Idiris, Alimjan ^a   Tohda, Hideki ^a   Kumagai, Hiromichi ^a   Takegawa, Kaoru ^b  

^a ASAHI GLASS CO LTD   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Glycosylation; Membrane trafficking; Protease; Protein folding; Secretion pathway; Yeast secretion system

Indexed keywords

EXPRESSION OF HETEROLOGOUS PROTEINS; FERMENTATION PROCESS; GENETIC MANIPULATIONS; GENETIC MODIFICATIONS; HIGH IMPACT; HIGH-DENSITY; HOST STRAIN; INDUSTRIAL PRODUCTION; MEMBRANE TRAFFICKING; MICROBIOLOGICAL SAFETY; PROTEASE; PROTEIN PRODUCTION; PROTEIN PURIFICATION PROCESS; PROTEIN SECRETION; RAPID GROWTH; SECRETION PATHWAY; SECRETION SYSTEMS; STRAIN ENGINEERING; SYSTEM BIOLOGY; SYSTEMATIC ENGINEERING; VECTOR SYSTEMS; YEAST STRAIN;

BIOLOGY; ENGINEERING; ESTERIFICATION; FERMENTATION; GENE EXPRESSION; GENETIC ENGINEERING; GLYCOSYLATION; PROTEIN FOLDING;

YEAST;

GLYCOPROTEIN; SECRETORY PROTEIN;

FERMENTATION; GENETIC ENGINEERING; INDUSTRIAL PRODUCTION; MICROORGANISM; PROTEIN; SECRETION; YEAST;

BIOSAFETY; DNA MODIFICATION; ENDOPLASMIC RETICULUM; FERMENTATION; GENE FUNCTION; GENE LOCATION; GENETIC ENGINEERING; GENETIC MANIPULATION; GLYCOSYLATION; INDUSTRIAL PRODUCTION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN SECRETION; SHORT SURVEY; SIGNAL TRANSDUCTION; YEAST;

GENETIC ENGINEERING; HUMANS; METABOLIC NETWORKS AND PATHWAYS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA;

EID: 77249147339     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-010-2447-0     Document Type: Short Survey

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