A novel fed-batch based cultivation method provides high cell-density and improves yield of soluble recombinant proteins in shaken cultures

Microbial Cell Factories

Volumn 9, Issue , 2010, Pages

  Krause, Mirja ^a,b   Ukkonen, Kaisa ^a   Haataja, Tatu ^a   Ruottinen, Maria ^a   Glumoff, Tuomo ^a   Neubauer, Antje ^a   Neubauer, Peter ^b   Vasala, Antti ^a  

^a UNIVERSITY OF OULU   (Finland)

^b TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; RECOMBINANT PROTEIN; OXYGEN;

ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIUM CULTURE; CELL DENSITY; CONTROLLED STUDY; CULTURE MEDIUM; DOWNSTREAM PROCESSING; ESCHERICHIA COLI; FED BATCH CULTURE; INTERMETHOD COMPARISON; NONHUMAN; PROCESS OPTIMIZATION; PROTEIN FOLDING; PROTEIN SYNTHESIS; BIOMASS; CULTURE TECHNIQUE; EVALUATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; METHODOLOGY;

ESCHERICHIA COLI;

BIOMASS; CULTURE MEDIA; CULTURE TECHNIQUES; ESCHERICHIA COLI; GLUCOSE; OXYGEN; RECOMBINANT PROTEINS;

EID: 77649311467     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-9-11     Document Type: Article

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