Changing the N-terminal sequence protects recombinant Plasmodium falciparum circumsporozoite protein from degradation in Pichia pastoris

Applied Microbiology and Biotechnology

Volumn 78, Issue 1, 2008, Pages 139-145

  Zhang, Qingfeng ^a   Ding, Feng ^a   Xue, Xiangyang ^a   Xu, Xindong ^a   Pan, Weiqing ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Circumsporozoite protein; Pichia pastoris; Plasmodium falciparum; Proteolytic degradation; Recombinant protein

Indexed keywords

AMINO ACIDS; BIODEGRADABILITY; GENE EXPRESSION; PURIFICATION; YEAST;

CIRCUMSPOROZOITE PROTEIN; PICHIA PASTORIS; PLASMODIUM FALCIPARUM; PROTEOLYTIC DEGRADATION; RECOMBINANT PROTEIN;

PROTEINS;

CIRCUMSPOROZOITE PROTEIN; RECOMBINANT PROTEIN;

AMINO ACID; ENZYME; GENE EXPRESSION; MUTATION; PEPTIDE; PROTEIN; PROTOZOAN; RECOMBINATION; YEAST;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; NONHUMAN; PICHIA PASTORIS; PLASMODIUM FALCIPARUM; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; PROTEIN STABILITY;

ANIMALS; EMULSIONS; MANNITOL; MUTAGENESIS, INSERTIONAL; OLEIC ACIDS; PICHIA; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS;

PICHIA PASTORIS; PLASMODIUM FALCIPARUM;

EID: 38349134764     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-007-1294-0     Document Type: Article

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