-
1
-
-
0035081475
-
Alzheimer's disease results from the cerebral accumula tion and cytotoxicity of amyloid P-protein
-
Selkoe DJ. Alzheimer's disease results from the cerebral accumula tion and cytotoxicity of amyloid P-protein. J Alzheimers Dis 3: 75-80 (2001).
-
(2001)
J Alzheimers Dis
, vol.3
, pp. 75-80
-
-
Selkoe, D.J.1
-
2
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
-
Dahlgren KN, Manelli AM, Stine WB, Jr., Baker LK, Krafft GA, la du MJ. Oligomeric and fibrillar species of amyloid-P peptides differentially affect neuronal viability. J Biol Chem 277: 32046-53 (2002).
-
(2002)
J Biol Chem
, vol.277
, pp. 32046-53
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
la du, M.J.6
-
3
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurode-generation: Separating the responsible protein aggregates from the innocent bystanders
-
Caughey B, Lansbury PT. Protofibrils, pores, fibrils, and neurode-generation: separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci 26: 267-98 (2003).
-
(2003)
Annu Rev Neurosci
, vol.26
, pp. 267-98
-
-
Caughey, B.1
Lansbury, P.T.2
-
4
-
-
0344980763
-
Elevation of mitochondrial glutathione by γ-glutamylcysteine ethyl ester protects mitochondria against peroxynitrite-induced oxidative stress
-
Drake J, Sultana R, Aksenova M, Calabrese V, Butterfield DA. Elevation of mitochondrial glutathione by γ-glutamylcysteine ethyl ester protects mitochondria against peroxynitrite-induced oxidative stress. J Neurosci Res 74: 917-27 (2003).
-
(2003)
J Neurosci Res
, vol.74
, pp. 917-27
-
-
Drake, J.1
Sultana, R.2
Aksenova, M.3
Calabrese, V.4
Butterfield, D.A.5
-
5
-
-
33751516713
-
Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide
-
Fawzi NL, Okabe Y, Yap EH, Head-Gordon T. Determining the critical nucleus and mechanism of fibril elongation of the Alzheimer's Abeta(1-40) peptide. J Mol Biol 365: 535-50 (2007).
-
(2007)
J Mol Biol
, vol.365
, pp. 535-50
-
-
Fawzi, N.L.1
Okabe, Y.2
Yap, E.H.3
Head-Gordon, T.4
-
6
-
-
0035339688
-
In vitro studies of amyloid P-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease
-
Walsh DM, Hartley DM, Condron MM, Selkoe DJ, Teplow DB. In vitro studies of amyloid P-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease. Biochem J 355: 869-77 (2001).
-
(2001)
Biochem J
, vol.355
, pp. 869-77
-
-
Walsh, D.M.1
Hartley, D.M.2
Condron, M.M.3
Selkoe, D.J.4
Teplow, D.B.5
-
7
-
-
33846282302
-
The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism
-
Shen J, Kelleher RJ. The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism. Proc Natl Acad Sci USA 104: 403-9 (2007).
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 403-409
-
-
Shen, J.1
Kelleher, R.J.2
-
8
-
-
0036736218
-
Amyloid precursor protein, presenilins, and asynuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease
-
Suh YH, Checler F. Amyloid precursor protein, presenilins, and asynuclein: Molecular pathogenesis and pharmacological applications in Alzheimer's disease. Pharmacol Rev 54: 469-525 (2002).
-
(2002)
Pharmacol Rev
, vol.54
, pp. 469-525
-
-
Suh, Y.H.1
Checler, F.2
-
9
-
-
0029166112
-
Apolipoprotein E genotypes and age of onset in early-onset familial Alzheimer's disease
-
Levy-Lahad E, Lahad A, Wijsman EM, Bird TD, Schellenberg GD. Apolipoprotein E genotypes and age of onset in early-onset familial Alzheimer's disease. Ann Neurol 38: 678-80 (1995).
-
(1995)
Ann Neurol
, vol.38
, pp. 678-80
-
-
Levy-Lahad, E.1
Lahad, A.2
Wijsman, E.M.3
Bird, T.D.4
Schellenberg, G.D.5
-
10
-
-
0034603525
-
Aberrant expression of nitric oxide synthase III in Alzheimer's disease: Relevance to cerebral vasculopathy and neurodegenera-tion
-
de la Monte SM, Lu BX, Sohn YK, Etienne D, Kraft J, Ganju N, et al. Aberrant expression of nitric oxide synthase III in Alzheimer's disease: Relevance to cerebral vasculopathy and neurodegeneration. Neurobiol Aging 21: 309-19 (2000).
-
(2000)
Neurobiol Aging
, vol.21
, pp. 309-19
-
-
de la Monte, S.M.1
Lu, B.X.2
Sohn, Y.K.3
Etienne, D.4
Kraft, J.5
Ganju, N.6
-
11
-
-
0030928406
-
P-Amyloid-associated free radical oxidative stress and neurotoxicity: Implications for Alzheimer's disease
-
Butterfield DA. P-Amyloid-associated free radical oxidative stress and neurotoxicity: Implications for Alzheimer's disease. Chem Res Toxicol 10: 495-506 (1997).
-
(1997)
Chem Res Toxicol
, vol.10
, pp. 495-506
-
-
Butterfield, D.A.1
-
12
-
-
0030915855
-
Oxidative stress hypothesis in Alzheimer's disease
-
Markesbery WR. Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 23: 134-47 (1997).
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 134-47
-
-
Markesbery, W.R.1
-
13
-
-
34547102265
-
Roles of amyloid P-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment
-
Butterfield DA, Reed T, Newman SF, Sultana R. Roles of amyloid P-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment. Free Radic Biol Med 43: 658-77 (2007).
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 658-77
-
-
Butterfield, D.A.1
Reed, T.2
Newman, S.F.3
Sultana, R.4
-
14
-
-
0030668223
-
Neuropathological criteria for the diagnosis of Alzheimer's disease
-
Markesbery WR. Neuropathological criteria for the diagnosis of Alzheimer's disease. Neurobiol Aging 18: S13-9 (1997).
-
(1997)
Neurobiol Aging
, vol.18
, pp. 13-19
-
-
Markesbery, W.R.1
-
15
-
-
0035194145
-
Evidence of oxidative damage in Alzheimer's disease brain: Central role for amyloid P-peptide
-
Butterfield DA, Drake J, Pocernich C, Castegna A. Evidence of oxidative damage in Alzheimer's disease brain: Central role for amyloid P-peptide. Trends Mol Med 7: 548-54 (2001).
-
(2001)
Trends Mol Med
, vol.7
, pp. 548-54
-
-
Butterfield, D.A.1
Drake, J.2
Pocernich, C.3
Castegna, A.4
-
16
-
-
15944426127
-
Amyloid accumulation and pathogensis of Alzheimer's disease: Significance of monomeric, oligomeric and fibrillar Ap
-
Glabe CC. Amyloid accumulation and pathogensis of Alzheimer's disease: Significance of monomeric, oligomeric and fibrillar Ap. Subcell Biochem 38: 167-77 (2005).
-
(2005)
Subcell Biochem
, vol.38
, pp. 167-77
-
-
Glabe, C.C.1
-
17
-
-
0034925118
-
The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: The role of AP(1-42)
-
Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR et al. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: The role of AP(1-42). J Neurochem 78: 413-6 (2001).
-
(2001)
J Neurochem
, vol.78
, pp. 413-416
-
-
Lauderback, C.M.1
Hackett, J.M.2
Huang, F.F.3
Keller, J.N.4
Szweda, L.I.5
Markesbery, W.R.6
-
18
-
-
0036591849
-
Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid P-peptide-associated free radical oxidative stress
-
Butterfield DA, Lauderback CM. Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid P-peptide-associated free radical oxidative stress. Free Radic Biol Med 32: 1050-60 (2002).
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1050-60
-
-
Butterfield, D.A.1
Lauderback, C.M.2
-
19
-
-
0036753272
-
Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death
-
Butterfield DA, Castegna A, Lauderback CM, Drake J. Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging 23: 655-64 (2002).
-
(2002)
Neurobiol Aging
, vol.23
, pp. 655-64
-
-
Butterfield, D.A.1
Castegna, A.2
Lauderback, C.M.3
Drake, J.4
-
20
-
-
0033788416
-
Vitamin E prevents Alzheimer's amyloid P-peptide (1-42)-induced neuronal protein oxidation and reactive oxygen species production
-
Yatin SM, Varadarajan S, Butterfield DA. Vitamin E prevents Alzheimer's amyloid P-peptide (1-42)-induced neuronal protein oxidation and reactive oxygen species production. J Alzheimers Dis 2: 123-31 (2000).
-
(2000)
J Alzheimers Dis
, vol.2
, pp. 123-31
-
-
Yatin, S.M.1
Varadarajan, S.2
Butterfield, D.A.3
-
21
-
-
0032799823
-
Vitamin E as an antioxidant/free radical scavenger against amyloid P-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: Insights into Alzheimer's disease
-
Butterfield DA, Koppal T, Subramaniam R, Yatin S. Vitamin E as an antioxidant/free radical scavenger against amyloid P-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: Insights into Alzheimer's disease. Rev Neurosci 10: 141-9 (1999).
-
(1999)
Rev Neurosci
, vol.10
, pp. 141-149
-
-
Butterfield, D.A.1
Koppal, T.2
Subramaniam, R.3
Yatin, S.4
-
22
-
-
0035910076
-
Delayed-onset ataxia in mice lacking a -tocopherol transfer protein: Model for neuronal degeneration caused by chronic oxidative stress
-
Yokota T, Igarashi K, Uchihara T, Jishage K, Tomita H, Inaba A, et al. Delayed-onset ataxia in mice lacking a -tocopherol transfer protein: Model for neuronal degeneration caused by chronic oxidative stress. Proc Natl Acad Sci USA 98: 15185-90 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15185-90
-
-
Yokota, T.1
Igarashi, K.2
Uchihara, T.3
Jishage, K.4
Tomita, H.5
Inaba, A.6
-
23
-
-
33749648745
-
Deletion of vitamin E enhances phenotype of Alzheimer disease model mouse
-
Nishida Y, Yokota T, Takahashi T, Uchihara T, Jishage K, Mi-zusawa H. Deletion of vitamin E enhances phenotype of Alzheimer disease model mouse. Biochem Biophys Res Commun 350: 530-6 (2006).
-
(2006)
Biochem Biophys Res Commun
, vol.350
, pp. 530-536
-
-
Nishida, Y.1
Yokota, T.2
Takahashi, T.3
Uchihara, T.4
Jishage, K.5
Mi-Zusawa, H.6
-
24
-
-
70450246963
-
Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease
-
Nishida Y, Ito S, Ohtsuki S, Yamamoto N, Takahashi T, Iwata N, et al. Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease. J Biol Chem 284: 33400-8 (2009).
-
(2009)
J Biol Chem
, vol.284
, pp. 33400-33408
-
-
Nishida, Y.1
Ito, S.2
Ohtsuki, S.3
Yamamoto, N.4
Takahashi, T.5
Iwata, N.6
-
25
-
-
70149117495
-
Dietary vitamin E, brain redox status and expression of Alzheimer's disease-relevant genes in rats
-
Gaedicke S, Zhang X, Huebbe P, Boesch-Saadatmandi C, Lou Y, Wiswedel I, et al. Dietary vitamin E, brain redox status and expression of Alzheimer's disease-relevant genes in rats. Br J Nutr 102: 398-406 (2009).
-
(2009)
Br J Nutr
, vol.102
, pp. 398-406
-
-
Gaedicke, S.1
Zhang, X.2
Huebbe, P.3
Boesch-Saadatmandi, C.4
Lou, Y.5
Wiswedel, I.6
-
26
-
-
0019258466
-
Tissue antioxidant status and related enzymes in rats with long term vitamin E deficiency
-
Chen LR, Thacker RR, Chow CK. Tissue antioxidant status and related enzymes in rats with long term vitamin E deficiency. Nutr Rep Int 22: 873-81 (1980).
-
(1980)
Nutr Rep Int
, vol.22
, pp. 873-81
-
-
Chen, L.R.1
Thacker, R.R.2
Chow, C.K.3
-
27
-
-
0023689064
-
Physiological antioxidants and antioxidative enzymes in vitamin E-deficient rats
-
De AK, Darad R. Physiological antioxidants and antioxidative enzymes in vitamin E-deficient rats. Toxicol Lett 44: 47-54 (1988).
-
(1988)
Toxicol Lett
, vol.44
, pp. 47-54
-
-
De, A.K.1
Darad, R.2
-
28
-
-
71049178586
-
Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice
-
Harrison FE, Allard J, Bixler R, Usoh C, Li L, May JM, et al. Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice. Nutr Neurosci 12: 203-18 (2009).
-
(2009)
Nutr Neurosci
, vol.12
, pp. 203-18
-
-
Harrison, F.E.1
Allard, J.2
Bixler, R.3
Usoh, C.4
Li, L.5
May, J.M.6
-
29
-
-
0028988757
-
Uptake of dietary RRR-α- and RRR-γ-tocopherol by nervous tissues, liver and muscle in vitamin-E-deficient rats
-
Clement M, Dinh L, Bourre JM. Uptake of dietary RRR-α- and RRR-γ-tocopherol by nervous tissues, liver and muscle in vitamin-E-deficient rats. Biochim Biophys Acta 1256: 175-80 (1995).
-
(1995)
Biochim Biophys Acta
, vol.1256
, pp. 175-80
-
-
Clement, M.1
Dinh, L.2
Bourre, J.M.3
-
30
-
-
0029809527
-
α-Tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: Dose-response study and correlations with plasma levels
-
Pappert EJ, Tangney CC, Goetz CG, Ling ZD, Lipton JW, Stebbins GT, et al. α-Tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: Dose-response study and correlations with plasma levels. Neurology 47: 1037-42 (1996).
-
(1996)
Neurology
, vol.47
, pp. 1037-42
-
-
Pappert, E.J.1
Tangney, C.C.2
Goetz, C.G.3
Ling, Z.D.4
Lipton, J.W.5
Stebbins, G.T.6
-
31
-
-
0023711866
-
Effect of high doses of dietary vitamin E on the concentrations of vitamin E in several brain regions, plasma, liver, and adipose tissue of rats
-
Vatassery GT, Brin MF, Fahn S, Kayden HJ, Traber MG. Effect of high doses of dietary vitamin E on the concentrations of vitamin E in several brain regions, plasma, liver, and adipose tissue of rats. J Neurochem 51: 621-3 (1988).
-
(1988)
J Neurochem
, vol.51
, pp. 621-623
-
-
Vatassery, G.T.1
Brin, M.F.2
Fahn, S.3
Kayden, H.J.4
Traber, M.G.5
-
32
-
-
14544300607
-
Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change
-
Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Ag-garwal NT, et al. Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr 81: 508-14 (2005).
-
(2005)
Am J Clin Nutr
, vol.81
, pp. 508-14
-
-
Morris, M.C.1
Evans, D.A.2
Tangney, C.C.3
Bienias, J.L.4
Wilson, R.S.5
Ag-Garwal, N.T.6
-
33
-
-
0037472341
-
Vitamin E isoforms α-tocotrienol and γ-tocopherol prevent cerebral infarction in mice
-
Mishima K, Tanaka T, Pu F, Egashira N, Iwasaki K, Hidaka R et al. Vitamin E isoforms α-tocotrienol and γ-tocopherol prevent cerebral infarction in mice. Neurosci Lett 337: 56-60 (2003).
-
(2003)
Neurosci Lett
, vol.337
, pp. 56-60
-
-
Mishima, K.1
Tanaka, T.2
Pu, F.3
Egashira, N.4
Iwasaki, K.5
Hidaka, R.6
-
34
-
-
0038375011
-
γ-Tocopherol, but not α-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats
-
Jiang Q, Ames BN. γ-Tocopherol, but not α-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats. FASEB J 17: 816-22 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 816-22
-
-
Jiang, Q.1
Ames, B.N.2
-
35
-
-
0037709474
-
The nitration product 5-nitro-γ-tocopherol is increased in the Alzheimer brain
-
Williamson KS, Gabbita SP, Mou S, West M, Pye QN, Markesbery WR et al. The nitration product 5-nitro-γ-tocopherol is increased in the Alzheimer brain. Nitric Oxide 6: 221-7 (2002).
-
(2002)
Nitric Oxide
, vol.6
, pp. 221-227
-
-
Williamson, K.S.1
Gabbita, S.P.2
Mou, S.3
West, M.4
Pye, Q.N.5
Markesbery, W.R.6
-
36
-
-
0037097008
-
Evidence for the nitration of γ-tocopherol in vivo: 5-nitro-γ-tocopherol is elevated in the plasma of subjects with coronary heart disease
-
Morton LW, Ward NC, Croft KD, Puddey IB. Evidence for the nitration of γ-tocopherol in vivo: 5-nitro-γ-tocopherol is elevated in the plasma of subjects with coronary heart disease. Biochem J 364: 625-8 (2002).
-
(2002)
Biochem J
, vol.364
, pp. 625-628
-
-
Morton, L.W.1
Ward, N.C.2
Croft, K.D.3
Puddey, I.B.4
-
37
-
-
0032531735
-
Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation
-
Hensley K, Maidt ML, Yu Z, Sang H, Markesbery WR, Floyd RA. Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. J Neurosci 18: 8126-32 (1998).
-
(1998)
J Neurosci
, vol.18
, pp. 8126-32
-
-
Hensley, K.1
Maidt, M.L.2
Yu, Z.3
Sang, H.4
Markesbery, W.R.5
Floyd, R.A.6
-
38
-
-
0022083255
-
Oral α-tocopherol supplements decrease plasma γ-tocopherol levels in humans
-
Handelman GJ, Machlin LJ, Fitch K, Weiter JJ, Dratz EA. Oral α-tocopherol supplements decrease plasma γ-tocopherol levels in humans. J Nutr 115: 807-13 (1985).
-
(1985)
J Nutr
, vol.115
, pp. 807-13
-
-
Handelman, G.J.1
Machlin, L.J.2
Fitch, K.3
Weiter, J.J.4
Dratz, E.A.5
-
39
-
-
0036342780
-
Nutritional approaches to combat oxidative stress in Alzheimer's disease
-
Butterfield D, Castegna A, Pocernich C, Drake J, Scapagnini G, Calabrese V. Nutritional approaches to combat oxidative stress in Alzheimer's disease. J Nutr Biochem 13: 444 (2002).
-
(2002)
J Nutr Biochem
, vol.13
, pp. 444
-
-
Butterfield, D.1
Castegna, A.2
Pocernich, C.3
Drake, J.4
Scapagnini, G.5
Calabrese, V.6
-
40
-
-
0033168643
-
Association of antioxidants with memory in a multiethnic elderly sample using the Third National Health and Nutrition Examination Survey
-
Perkins AJ, Hendrie HC, Callahan CM, Gao S, Unverzagt FW, Xu Y, et al. Association of antioxidants with memory in a multiethnic elderly sample using the Third National Health and Nutrition Examination Survey. Am J Epidemiol 150: 37-44 (1999).
-
(1999)
Am J Epidemiol
, vol.150
, pp. 37-44
-
-
Perkins, A.J.1
Hendrie, H.C.2
Callahan, C.M.3
Gao, S.4
Unverzagt, F.W.5
Xu, Y.6
-
41
-
-
0035425880
-
Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease
-
Kontush A, Mann U, Arlt S, Ujeyl A, Luhrs C, Muller-Thomsen T, et al. Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease. Free Radic Biol Med 31: 345-54 (2001).
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 345-54
-
-
Kontush, A.1
Mann, U.2
Arlt, S.3
Ujeyl, A.4
Luhrs, C.5
Muller-Thomsen, T.6
-
42
-
-
28544453282
-
Dementia and Alzheimer's disease in community-dwelling elders taking vitamin C and/or vitamin E
-
Fillenbaum GG, Kuchibhatla MN, Hanlon JT, Artz MB, Pieper CF, Schmader KE, et al. Dementia and Alzheimer's disease in community-dwelling elders taking vitamin C and/or vitamin E. Ann Phar-macother 39: 2009-14 (2005).
-
(2005)
Ann Phar-macother
, vol.39
, pp. 2009-14
-
-
Fillenbaum, G.G.1
Kuchibhatla, M.N.2
Hanlon, J.T.3
Artz, M.B.4
Pieper, C.F.5
Schmader, K.E.6
-
43
-
-
2342608923
-
Midlife dietary intake of antioxidants and risk of late-life incident dementia: The Honolulu-Asia Aging Study
-
Laurin D, Masaki KH, Foley DJ, White LR, Launer LJ. Midlife dietary intake of antioxidants and risk of late-life incident dementia: The Honolulu-Asia Aging Study. Am J Epidemiol 159: 959-67 (2004).
-
(2004)
Am J Epidemiol
, vol.159
, pp. 959-67
-
-
Laurin, D.1
Masaki, K.H.2
Foley, D.J.3
White, L.R.4
Launer, L.J.5
-
45
-
-
0033966803
-
Alzheimer disease: Protective factors
-
Nourhashemi F, Gillette-Guyonnet S, Andrieu S, Ghisolfi A, Ous-set PJ, Grandjean H, et al. Alzheimer disease: Protective factors. Am J Clin Nutr 71: 643S-649S (2000).
-
(2000)
Am J Clin Nutr
, vol.71
-
-
Nourhashemi, F.1
Gillette-Guyonnet, S.2
Andrieu, S.3
Ghisolfi, A.4
Ous-Set, P.J.5
Grandjean, H.6
-
46
-
-
0034837151
-
Effect of vitamin and trace-element supplementation on cognitive function in elderly subjects
-
Chandra RK. Effect of vitamin and trace-element supplementation on cognitive function in elderly subjects. Nutrition 17: 709-12 (2001).
-
(2001)
Nutrition
, vol.17
, pp. 709-12
-
-
Chandra, R.K.1
-
47
-
-
0346688728
-
Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: The Cache County Study
-
Zandi PP, Anthony JC, Khachaturian AS, Stone SV, Gustafson D, Tschanz JT, et al. Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: The Cache County Study. Arch Neurol 61: 82-8 (2004).
-
(2004)
Arch Neurol
, vol.61
, pp. 82-88
-
-
Zandi, P.P.1
Anthony, J.C.2
Khachaturian, A.S.3
Stone, S.V.4
Gustafson, D.5
Tschanz, J.T.6
-
48
-
-
0032420027
-
Vitamin E and vitamin C supplement use and risk of incident Alzheimer disease
-
Morris MC, Beckett LA, Scherr PA, Hebert LE, Bennett DA, Field TS, et al. Vitamin E and vitamin C supplement use and risk of incident Alzheimer disease. Alzheimer Dis Assoc Disord 12: 121-6 (1998).
-
(1998)
Alzheimer Dis Assoc Disord
, vol.12
, pp. 121-126
-
-
Morris, M.C.1
Beckett, L.A.2
Scherr, P.A.3
Hebert, L.E.4
Bennett, D.A.5
Field, T.S.6
-
49
-
-
0037178573
-
Dietary intake of antioxidants and risk of Alzheimer disease
-
Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JC, et al. Dietary intake of antioxidants and risk of Alzheimer disease. JAMA 287: 3223-9 (2002).
-
(2002)
JAMA
, vol.287
, pp. 3223-3229
-
-
Engelhart, M.J.1
Geerlings, M.I.2
Ruitenberg, A.3
van Swieten, J.C.4
Hofman, A.5
Witteman, J.C.6
-
50
-
-
0030967165
-
A controlled trial of selegiline, α-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study
-
Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grund-man M, et al. A controlled trial of selegiline, α-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N Engl J Med 336: 1216-22 (1997).
-
(1997)
N Engl J Med
, vol.336
, pp. 1216-22
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
Klauber, M.R.4
Schafer, K.5
Grund-Man, M.6
-
52
-
-
67650921433
-
Vitamin E paradox in Alzheimer's disease: It does not prevent loss of cognition and may even be detrimental
-
Lloret A, Badia MC, Mora NJ, Pallardo FV, Alonso MD, Vina J. Vitamin E paradox in Alzheimer's disease: It does not prevent loss of cognition and may even be detrimental. J Alzheimers Dis 17: 143-9 (2009).
-
(2009)
J Alzheimers Dis
, vol.17
, pp. 143-149
-
-
Lloret, A.1
Badia, M.C.2
Mora, N.J.3
Pallardo, F.V.4
Alonso, M.D.5
Vina, J.6
-
53
-
-
11144261790
-
Oxidatively modified GST and MRP1 in Alzheimer's disease brain: Implications for accumulation of reactive lipid peroxidation products
-
Sultana R, Butterfield DA. Oxidatively modified GST and MRP1 in Alzheimer's disease brain: Implications for accumulation of reactive lipid peroxidation products. Neurochem Res 29: 2215-20 (2004).
-
(2004)
Neurochem Res
, vol.29
, pp. 2215-20
-
-
Sultana, R.1
Butterfield, D.A.2
-
54
-
-
0033021424
-
ATP-and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1
-
Renes J, de Vries EG, Nienhuis EF, Jansen PL, Muller M. ATP-and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1. Br J Pharmacol 126: 681-8 (1999).
-
(1999)
Br J Pharmacol
, vol.126
, pp. 681-688
-
-
Renes, J.1
de Vries, E.G.2
Nienhuis, E.F.3
Jansen, P.L.4
Muller, M.5
-
55
-
-
0034714319
-
Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis
-
Chrestensen CA, Starke DW, Mieyal JJ. Acute cadmium exposure inactivates thioltransferase (Glutaredoxin), inhibits intracellular reduction of protein-glutathionyl-mixed disulfides, and initiates apoptosis. J Biol Chem 275: 26556-65 (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 26556-65
-
-
Chrestensen, C.A.1
Starke, D.W.2
Mieyal, J.J.3
-
56
-
-
34248223082
-
An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach
-
Newman SF, Sultana R, Perluigi M, Coccia R, Cai J, Pierce WM, et al. An increase in S-glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach. J Neurosci Res 85: 1506-14 (2007).
-
(2007)
J Neurosci Res
, vol.85
, pp. 1506-14
-
-
Newman, S.F.1
Sultana, R.2
Perluigi, M.3
Coccia, R.4
Cai, J.5
Pierce, W.M.6
-
57
-
-
62349084020
-
Glutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: Implications for AD pathogenesis
-
di Domenico F, Cenini G, Sultana R, Perluigi M, Uberti D, Memo M, et al. Glutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: Implications for AD pathogenesis. Neurochem Res 34: 727-33 (2009).
-
(2009)
Neurochem Res
, vol.34
, pp. 727-33
-
-
di Domenico, F.1
Cenini, G.2
Sultana, R.3
Perluigi, M.4
Uberti, D.5
Memo, M.6
-
58
-
-
0036733145
-
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: Dihydropyrimidinase-related protein 2, α-enolase and heat shock cognate 71
-
Castegna A, Aksenov M, Thongboonkerd V, Klein JB, Pierce WM, Booze R et al. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: Dihydropyrimidinase-related protein 2, α-enolase and heat shock cognate 71. J Neurochem 82: 1524-32 (2002).
-
(2002)
J Neurochem
, vol.82
, pp. 1524-32
-
-
Castegna, A.1
Aksenov, M.2
Thongboonkerd, V.3
Klein, J.B.4
Pierce, W.M.5
Booze, R.6
-
59
-
-
0037101889
-
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: Creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1
-
Castegna A, Aksenov M, Aksenova M, Thongboonkerd V, Klein JB, Pierce WM, et al. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: Creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radic Biol Med 33: 562-71 (2002).
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 562-71
-
-
Castegna, A.1
Aksenov, M.2
Aksenova, M.3
Thongboonkerd, V.4
Klein, J.B.5
Pierce, W.M.6
-
60
-
-
33644913675
-
Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around AP(1-42)
-
Sultana R, Perluigi M, Butterfield DA. Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Aβ(1-42). J Chromatogr B Analyt Technol Biomed Life Sci 833: 3-11 (2006).
-
(2006)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.833
, pp. 3-11
-
-
Sultana, R.1
Perluigi, M.2
Butterfield, D.A.3
-
61
-
-
0031797832
-
Glucose intolerance, cognitive impairment and Alzheimer's disease
-
Vanhanen M, Soininen H. Glucose intolerance, cognitive impairment and Alzheimer's disease. Curr Opin Neurol 11: 673-7 (1998).
-
(1998)
Curr Opin Neurol
, vol.11
, pp. 673-677
-
-
Vanhanen, M.1
Soininen, H.2
-
62
-
-
0034652426
-
Age-associated decline in γ-glutamylcysteine synthetase gene expression in rats
-
Liu R, Choi J. Age-associated decline in γ-glutamylcysteine synthetase gene expression in rats. Free Radic Biol Med 28: 566-74 (2000).
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 566-74
-
-
Liu, R.1
Choi, J.2
-
63
-
-
33947606911
-
Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease
-
Calabrese V, Sultana R, Scapagnini G, Guagliano E, Sapienza M, Bella R et al. Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxid Redox Signal 8: 1975-86 (2006).
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1975-86
-
-
Calabrese, V.1
Sultana, R.2
Scapagnini, G.3
Guagliano, E.4
Sapienza, M.5
Bella, R.6
-
64
-
-
0034087231
-
Mild cognitive impairment: Transition between aging and Alzheimer's disease
-
Petersen RC. Mild cognitive impairment: Transition between aging and Alzheimer's disease. Neurologia 15: 93-101 (2000).
-
(2000)
Neurologia
, vol.15
, pp. 93-101
-
-
Petersen, R.C.1
-
65
-
-
28244465525
-
What is a mild cognitive impairment?
-
Portet F, Ousset PJ, Touchon J. [What is a mild cognitive impairment?]. Rev Prat 55: 1891-4 (2005).
-
(2005)
Rev Prat
, vol.55
, pp. 1891-1894
-
-
Portet, F.1
Ousset, P.J.2
Touchon, J.3
-
66
-
-
56349091788
-
Protein levels and activity of some antioxidant enzymes in hippocampus of subjects with amnestic mild cognitive impairment
-
Sultana R, Piroddi M, Galli F, Butterfield DA. Protein levels and activity of some antioxidant enzymes in hippocampus of subjects with amnestic mild cognitive impairment. Neurochem Res 33: 2540-6 (2008).
-
(2008)
Neurochem Res
, vol.33
, pp. 2540-2546
-
-
Sultana, R.1
Piroddi, M.2
Galli, F.3
Butterfield, D.A.4
-
67
-
-
0031678044
-
Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease
-
Lovell MA, Xie C, Markesbery WR. Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease. Neurology 51: 1562-6 (1998).
-
(1998)
Neurology
, vol.51
, pp. 1562-1566
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
68
-
-
0032533744
-
Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity
-
Xie C, Lovell MA, Markesbery WR. Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity. Free Radic Biol Med 25: 979-88 (1998).
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 979-88
-
-
Xie, C.1
Lovell, M.A.2
Markesbery, W.R.3
-
69
-
-
0032435767
-
Glutathione therapy: From prodrugs to genes
-
Anderson ME, Luo JL. Glutathione therapy: From prodrugs to genes. Semin Liver Dis 18: 415-24 (1998).
-
(1998)
Semin Liver Dis
, vol.18
, pp. 415-24
-
-
Anderson, M.E.1
Luo, J.L.2
-
70
-
-
0037342554
-
The antioxidants α-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice
-
Farr SA, Poon HF, Dogrukol-Ak D, Drake J, Banks WA, Eyerman E, et al. The antioxidants α-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem 84: 1173-83 (2003).
-
(2003)
J Neurochem
, vol.84
, pp. 1173-83
-
-
Farr, S.A.1
Poon, H.F.2
Dogrukol-Ak, D.3
Drake, J.4
Banks, W.A.5
Eyerman, E.6
-
71
-
-
0033043959
-
In vivo modulation of rodent glutathione and its role in peroxynitrite-induced neocortical synaptosomal membrane protein damage
-
Koppal T, Drake J, Butterfield DA. In vivo modulation of rodent glutathione and its role in peroxynitrite-induced neocortical synaptosomal membrane protein damage. Biochim Biophys Acta 1453: 407-11 (1999).
-
(1999)
Biochim Biophys Acta
, vol.1453
, pp. 407-11
-
-
Koppal, T.1
Drake, J.2
Butterfield, D.A.3
-
72
-
-
0034988283
-
Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: Relevance to brain lipid peroxidation in neurodegenerative disease
-
Pocernich CB, Cardin AL, Racine CL, Lauderback CM, Butterfield DA. Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: Relevance to brain lipid peroxidation in neurodegenerative disease. Neurochem Int 39: 141-9 (2001).
-
(2001)
Neurochem Int
, vol.39
, pp. 141-149
-
-
Pocernich, C.B.1
Cardin, A.L.2
Racine, C.L.3
Lauderback, C.M.4
Butterfield, D.A.5
-
73
-
-
0033967664
-
In vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain
-
Pocernich CB, La Fontaine M, Butterfield DA. In vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain. Neurochem Int 36: 185-91 (2000).
-
(2000)
Neurochem Int
, vol.36
, pp. 185-91
-
-
Pocernich, C.B.1
la Fontaine, M.2
Butterfield, D.A.3
-
74
-
-
33747762642
-
Protective effect of N-acetyl-L-cysteine on amyloid P-peptide-induced learning and memory deficits in mice
-
Fu AL, Dong ZH, Sun MJ. Protective effect of N-acetyl-L-cysteine on amyloid P-peptide-induced learning and memory deficits in mice. Brain Res 1109: 201-6 (2006).
-
(2006)
Brain Res
, vol.1109
, pp. 201-206
-
-
Fu, A.L.1
Dong, Z.H.2
Sun, M.J.3
-
75
-
-
31344479849
-
Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from AP(1-42) toxicity
-
Bartov O, Sultana R, Butterfield DA, Atlas D. Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from AP(1-42) toxicity. Brain Res 1069: 198-206 (2006).
-
(2006)
Brain Res
, vol.1069
, pp. 198-206
-
-
Bartov, O.1
Sultana, R.2
Butterfield, D.A.3
Atlas, D.4
-
76
-
-
63849264211
-
Different protection of K252a and N-acetyl-L-cysteine against amyloid-P peptide-induced cortical neuron apoptosis involving inhibition of MLK3-MKK7-JNK3 signal cascades
-
Xu Y, Hou XY, Liu Y, Zong YY. Different protection of K252a and N-acetyl-L-cysteine against amyloid-P peptide-induced cortical neuron apoptosis involving inhibition of MLK3-MKK7-JNK3 signal cascades. J Neurosci Res 87: 918-27 (2009).
-
(2009)
J Neurosci Res
, vol.87
, pp. 918-27
-
-
Xu, Y.1
Hou, X.Y.2
Liu, Y.3
Zong, Y.Y.4
-
77
-
-
57049099718
-
N-acetylcysteine prevents P-amyloid toxicity by a stimulatory effect on p35/cyclin-dependent kinase 5 activity in cultured cortical neurons
-
Hsiao YH, Chen PS, Yeh SH, Lin CH, Gean PW. N-acetylcysteine prevents P-amyloid toxicity by a stimulatory effect on p35/cyclin-dependent kinase 5 activity in cultured cortical neurons. J Neurosci Res 86: 2685-95 (2008).
-
(2008)
J Neurosci Res
, vol.86
, pp. 2685-95
-
-
Hsiao, Y.H.1
Chen, P.S.2
Yeh, S.H.3
Lin, C.H.4
Gean, P.W.5
-
78
-
-
0344878874
-
Prevention of PC 12 cell death by N-acetylcysteine requires activation of the Ras pathway
-
Yan CY, Greene LA. Prevention of PC 12 cell death by N-acetylcysteine requires activation of the Ras pathway. J Neurosci 18: 4042-9 (1998).
-
(1998)
J Neurosci
, vol.18
, pp. 4042-4049
-
-
Yan, C.Y.1
Greene, L.A.2
-
79
-
-
0030808462
-
Aggregated amyloid-P protein induces cortical neuronal apoptosis and concomitant apoptotic pattern of gene induction
-
Estus S, Tucker HM, van Rooyen C, Wright S, Brigham EF, Wogulis M, et al. Aggregated amyloid-P protein induces cortical neuronal apoptosis and concomitant apoptotic pattern of gene induction. J Neurosci 17: 7736-45 (1997).
-
(1997)
J Neurosci
, vol.17
, pp. 7736-45
-
-
Estus, S.1
Tucker, H.M.2
van Rooyen, C.3
Wright, S.4
Brigham, E.F.5
Wogulis, M.6
-
80
-
-
0034882971
-
N-Acetyl-L-cysteine downregulates P-amyloid precursor protein gene transcription in human neuroblastoma cells
-
Studer R, Baysang G, Brack C. N-Acetyl-L-cysteine downregulates P-amyloid precursor protein gene transcription in human neuroblastoma cells. Biogerontology 2: 55-60 (2001).
-
(2001)
Biogerontology
, vol.2
, pp. 55-60
-
-
Studer, R.1
Baysang, G.2
Brack, C.3
-
81
-
-
33745602472
-
RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetylcysteine
-
Tucker S, Ahl M, Cho HH, Bandyopadhyay S, Cuny GD, Bush AI, et al. RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetylcysteine. Curr Alzheimer Res 3: 221-7 (2006).
-
(2006)
Curr Alzheimer Res
, vol.3
, pp. 221-227
-
-
Tucker, S.1
Ahl, M.2
Cho, H.H.3
Bandyopadhyay, S.4
Cuny, G.D.5
Bush, A.I.6
-
82
-
-
0035168757
-
N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: Effects on P-amyloid secretion and tau phosphorylation
-
Olivieri G, Baysang G, Meier F, Muller-Spahn F, Stahelin HB, Brockhaus M, et al. N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: Effects on P-amyloid secretion and tau phosphorylation. J Neurochem 76: 224-33 (2001).
-
(2001)
J Neurochem
, vol.76
, pp. 224-33
-
-
Olivieri, G.1
Baysang, G.2
Meier, F.3
Muller-Spahn, F.4
Stahelin, H.B.5
Brockhaus, M.6
-
83
-
-
70350348150
-
Inhibition of P 1-40 amyloid fibrillation with N-acetyl-L-cysteine capped quantum dots
-
Xiao L, Zhao D, Chan WH, Choi MM, Li HW. Inhibition of P 1-40 amyloid fibrillation with N-acetyl-L-cysteine capped quantum dots. Biomaterials 31: 91-8 (2010).
-
(2010)
Biomaterials
, vol.31
, pp. 91-98
-
-
Xiao, L.1
Zhao, D.2
Chan, W.H.3
Choi, M.M.4
Li, H.W.5
-
84
-
-
20944435413
-
Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging
-
Wang DS, Lipton RB, Katz MJ, Davies P, Buschke H, Kuslansky G, et al. Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging. J Neuropathol Exp Neurol 64: 378-85 (2005).
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 378-85
-
-
Wang, D.S.1
Lipton, R.B.2
Katz, M.J.3
Davies, P.4
Buschke, H.5
Kuslansky, G.6
-
85
-
-
0141514419
-
Oxidized neprilysin in aging and Alzheimer's disease brains
-
Wang DS, Iwata N, Hama E, Saido TC, Dickson DW. Oxidized neprilysin in aging and Alzheimer's disease brains. Biochem Biophys Res Commun 310: 236-41 (2003).
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 236-41
-
-
Wang, D.S.1
Iwata, N.2
Hama, E.3
Saido, T.C.4
Dickson, D.W.5
-
86
-
-
75149149244
-
N-acetylcysteine prevents 4-hydroxynonenal- and amyloid-P-induced modification and inacti-vation of neprilysin in SH-SY5Y cells
-
Wang R, Malter JS, Wang DS. N-acetylcysteine prevents 4-hydroxynonenal- and amyloid-P-induced modification and inacti-vation of neprilysin in SH-SY5Y cells. J Alzheimers Dis 19: 179-89 (2010).
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 179-89
-
-
Wang, R.1
Malter, J.S.2
Wang, D.S.3
-
87
-
-
0035940625
-
Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease
-
Adair JC, Knoefel JE, Morgan N. Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease. Neurology 57: 1515-7 (2001).
-
(2001)
Neurology
, vol.57
, pp. 1515-1517
-
-
Adair, J.C.1
Knoefel, J.E.2
Morgan, N.3
-
88
-
-
63349096757
-
Efficacy of a vita-min/nutriceutical formulation for moderate-stage to later-stage Alzheimer's disease: A placebo-controlled pilot study
-
Remington R, Chan A, Paskavitz J, Shea TB. Efficacy of a vita-min/nutriceutical formulation for moderate-stage to later-stage Alzheimer's disease: A placebo-controlled pilot study. Am J Alzheimers Dis Other Demen 24: 27-33 (2009).
-
(2009)
Am J Alzheimers Dis Other Demen
, vol.24
, pp. 27-33
-
-
Remington, R.1
Chan, A.2
Paskavitz, J.3
Shea, T.B.4
-
89
-
-
0020662578
-
Transport and direct utilization of γ-glutamylcyst(e)ine for glutathione synthesis
-
Anderson ME, Meister A. Transport and direct utilization of γ-glutamylcyst(e)ine for glutathione synthesis. Proc Natl Acad Sci USA 80: 707-11 (1983).
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 707-11
-
-
Anderson, M.E.1
Meister, A.2
-
90
-
-
0037097270
-
Elevation of brain glutathione by γ-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress
-
Drake J, Kanski J, Varadarajan S, Tsoras M, Butterfield DA. Elevation of brain glutathione by γ-glutamylcysteine ethyl ester protects against peroxynitrite-induced oxidative stress. J Neurosci Res 68: 776-84 (2002).
-
(2002)
J Neurosci Res
, vol.68
, pp. 776-84
-
-
Drake, J.1
Kanski, J.2
Varadarajan, S.3
Tsoras, M.4
Butterfield, D.A.5
-
91
-
-
16444379174
-
γ-glutamylcysteine ethyl ester-induced up-regulation of glutathione protects neurons against AP(1-42)-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease
-
Boyd-Kimball D, Sultana R, Abdul HM, Butterfield DA. γ-glutamylcysteine ethyl ester-induced up-regulation of glutathione protects neurons against AP(1-42)-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease. J Neurosci Res 79: 700-6 (2005).
-
(2005)
J Neurosci Res
, vol.79
, pp. 700-706
-
-
Boyd-Kimball, D.1
Sultana, R.2
Abdul, H.M.3
Butterfield, D.A.4
-
92
-
-
16444385872
-
γ-glutamylcysteine ethyl ester protection of proteins from AP(1-42)-mediated oxidative stress in neuronal cell culture: A proteomics approach
-
Boyd-Kimball D, Sultana R, Poon HF, Mohmmad-Abdul H, Lynn BC, Klein JB, et al. γ-glutamylcysteine ethyl ester protection of proteins from AP(1-42)-mediated oxidative stress in neuronal cell culture: A proteomics approach. J Neurosci Res 79: 707-13 (2005).
-
(2005)
J Neurosci Res
, vol.79
, pp. 707-13
-
-
Boyd-Kimball, D.1
Sultana, R.2
Poon, H.F.3
Mohmmad-Abdul, H.4
Lynn, B.C.5
Klein, J.B.6
-
93
-
-
0038452658
-
Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity
-
Abramov AY, Canevari L, Duchen MR. Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity. J Neurosci 23: 5088-95 (2003).
-
(2003)
J Neurosci
, vol.23
, pp. 5088-95
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
94
-
-
0036827988
-
Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor a, dopamine and P-amyloid peptide 1-42
-
Medina S, Martinez M, Hernanz A. Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor a, dopamine and P-amyloid peptide 1-42. Free Radic Res 36: 1179-84 (2002).
-
(2002)
Free Radic Res
, vol.36
, pp. 1179-84
-
-
Medina, S.1
Martinez, M.2
Hernanz, A.3
-
95
-
-
0142107442
-
Is glutathione an important neuroprotective effector molecule against amyloid P toxicity?
-
Barber VS, Griffiths HR. Is glutathione an important neuroprotective effector molecule against amyloid P toxicity? Biofactors 17: 215-28 (2003).
-
(2003)
Biofactors
, vol.17
, pp. 215-28
-
-
Barber, V.S.1
Griffiths, H.R.2
-
96
-
-
0029909010
-
Neuroprotection by the metabolic antioxidant α-lipoic acid
-
Packer L, Tritschler HJ, Wessel K. Neuroprotection by the metabolic antioxidant α-lipoic acid. Free Radic Biol Med 22: 359-78 (1997).
-
(1997)
Free Radic Biol Med
, vol.22
, pp. 359-78
-
-
Packer, L.1
Tritschler, H.J.2
Wessel, K.3
-
97
-
-
0026580999
-
Recycling of vitamin E in human low density lipoproteins
-
Kagan VE, Serbinova EA, Forte T, Scita G, Packer L. Recycling of vitamin E in human low density lipoproteins. J Lipid Res 33: 385-97 (1992).
-
(1992)
J Lipid Res
, vol.33
, pp. 385-97
-
-
Kagan, V.E.1
Serbinova, E.A.2
Forte, T.3
Scita, G.4
Packer, L.5
-
98
-
-
0029873732
-
The isomers of thioctic acid alter C-deoxyglucose incorporation in rat basal ganglia
-
Seaton TA, Jenner P, Marsden CD. The isomers of thioctic acid alter C-deoxyglucose incorporation in rat basal ganglia. Biochem Pharmacol 51: 983-6 (1996).
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 983-986
-
-
Seaton, T.A.1
Jenner, P.2
Marsden, C.D.3
-
99
-
-
28544442225
-
PET is better than perfusion SPECT for early diagnosis of Alzheimer's disease -- for
-
Ishii K, Minoshima S. PET is better than perfusion SPECT for early diagnosis of Alzheimer's disease -- for. Eur J Nucl Med Mol Imaging 32: 1463-5 (2005).
-
(2005)
Eur J Nucl Med Mol Imaging
, vol.32
, pp. 1463-1465
-
-
Ishii, K.1
Minoshima, S.2
-
100
-
-
0142010609
-
Protection against amyloid P-peptide and iron/hydrogen peroxide toxicity by α-lipoic acid
-
Lovell MA, Xie C, Xiong S, Markesbery WR. Protection against amyloid P-peptide and iron/hydrogen peroxide toxicity by α-lipoic acid. J Alzheimers Dis 5: 229-39 (2003).
-
(2003)
J Alzheimers Dis
, vol.5
, pp. 229-39
-
-
Lovell, M.A.1
Xie, C.2
Xiong, S.3
Markesbery, W.R.4
-
101
-
-
0035955513
-
α-Lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway
-
Zhang L, Xing GQ, Barker JL, Chang Y, Maric D, Ma W, et al. α-Lipoic acid protects rat cortical neurons against cell death induced by amyloid and hydrogen peroxide through the Akt signalling pathway. Neurosci Lett 312: 125-8 (2001).
-
(2001)
Neurosci Lett
, vol.312
, pp. 125-128
-
-
Zhang, L.1
Xing, G.Q.2
Barker, J.L.3
Chang, Y.4
Maric, D.5
Ma, W.6
-
103
-
-
0034667741
-
Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures
-
Lovell MA, Xie C, Markesbery WR. Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures. Free Radic Biol Med 29: 714-20 (2000).
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 714-20
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
104
-
-
1342306400
-
Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease
-
Pocernich CB, Butterfield DA. Acrolein inhibits NADH-linked mitochondrial enzyme activity: Implications for Alzheimer's disease. Neurotox Res 5: 515-20 (2003).
-
(2003)
Neurotox Res
, vol.5
, pp. 515-20
-
-
Pocernich, C.B.1
Butterfield, D.A.2
-
105
-
-
0035216624
-
Effect of DL-alpha-lipoic acid on glutathione metabolic enzymes in aged rats
-
Arivazhagan P, Ramanathan K, Panneerselvam C. Effect of DL-alpha-lipoic acid on glutathione metabolic enzymes in aged rats. Exp Gerontol 37: 81-7 (2001).
-
(2001)
Exp Gerontol
, vol.37
, pp. 81-87
-
-
Arivazhagan, P.1
Ramanathan, K.2
Panneerselvam, C.3
-
106
-
-
0022930972
-
Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains
-
Nordberg A, Winblad B. Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains. Neurosci Lett 72: 115-9 (1986).
-
(1986)
Neurosci Lett
, vol.72
, pp. 115-119
-
-
Nordberg, A.1
Winblad, B.2
-
107
-
-
0033658389
-
Regulation of the activity of choline acetyl transferase by lipoic acid
-
Haugaard N, Levin RM. Regulation of the activity of choline acetyl transferase by lipoic acid. Mol Cell Biochem 213: 61-3 (2000).
-
(2000)
Mol Cell Biochem
, vol.213
, pp. 61-63
-
-
Haugaard, N.1
Levin, R.M.2
-
108
-
-
0036184821
-
Activation of choline acetyl transferase by dihydrolipoic acid
-
Haugaard N, Levin RM. Activation of choline acetyl transferase by dihydrolipoic acid. Mol Cell Biochem 229: 103-6 (2002).
-
(2002)
Mol Cell Biochem
, vol.229
, pp. 103-106
-
-
Haugaard, N.1
Levin, R.M.2
-
109
-
-
0027195933
-
Seeding one-dimensional crystallization of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
-
Jarrett JT, Lansbury PT. Seeding one-dimensional crystallization of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73: 1055-8 (1993).
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury, P.T.2
-
110
-
-
32344435392
-
α-Lipoic acid exhibits anti-amyloidogenicity for P-amyloid fibrils in vitro
-
Ono K, Hirohata M, Yamada M. α-Lipoic acid exhibits anti-amyloidogenicity for P-amyloid fibrils in vitro. Biochem Biophys Res Commun 341: 1046-52 (2006).
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 1046-52
-
-
Ono, K.1
Hirohata, M.2
Yamada, M.3
-
111
-
-
41349084346
-
Inhibitory effects of short-term administration of DL-α-lipoic acid on oxidative vulnerability induced by AP amyloid fibrils (25-35) in mice
-
Jesudason EP, Masilamoni JG, Ashok BS, Baben B, Arul V, Jesu-doss KS, et al. Inhibitory effects of short-term administration of DL-α-lipoic acid on oxidative vulnerability induced by AP amyloid fibrils (25-35) in mice. Mol Cell Biochem 311: 145-56 (2008).
-
(2008)
Mol Cell Biochem
, vol.311
, pp. 145-56
-
-
Jesudason, E.P.1
Masilamoni, J.G.2
Ashok, B.S.3
Baben, B.4
Arul, V.5
Jesu-Doss, K.S.6
-
112
-
-
1542723493
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
-
Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu RM, et al. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci USA 101: 3381-6 (2004).
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3381-3386
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
Liu, H.4
Jaiswal, A.K.5
Liu, R.M.6
-
113
-
-
1042290476
-
(R)-α-Lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: Evidence for increased cysteine requirement for GSH synthesis
-
Suh JH, Wang H, Liu RM, Liu J, Hagen TM. (R)-α-Lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: Evidence for increased cysteine requirement for GSH synthesis. Arch Biochem Biophys 423: 126-35 (2004).
-
(2004)
Arch Biochem Biophys
, vol.423
, pp. 126-35
-
-
Suh, J.H.1
Wang, H.2
Liu, R.M.3
Liu, J.4
Hagen, T.M.5
-
114
-
-
0024211998
-
Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory
-
Yagi H, Katoh S, Akiguchi I, Takeda T. Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory. Brain Res 474: 86-93 (1988).
-
(1988)
Brain Res
, vol.474
, pp. 86-93
-
-
Yagi, H.1
Katoh, S.2
Akiguchi, I.3
Takeda, T.4
-
115
-
-
0027476481
-
Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM)
-
Flood JF, Morley JE. Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM). Neurobiol Aging 14: 153-7 (1993).
-
(1993)
Neurobiol Aging
, vol.14
, pp. 153-157
-
-
Flood, J.F.1
Morley, J.E.2
-
116
-
-
0032566721
-
Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress brain
-
Fujibayashi Y, Yamamoto S, Waki A, Konishi J, Yonekura Y. Increased mitochondrial DNA deletion in the brain of SAMP8, a mouse model for spontaneous oxidative stress brain. Neurosci Lett 254: 109-12 (1998).
-
(1998)
Neurosci Lett
, vol.254
, pp. 109-12
-
-
Fujibayashi, Y.1
Yamamoto, S.2
Waki, A.3
Konishi, J.4
Yonekura, Y.5
-
117
-
-
0027936618
-
Electron paramagnetic resonance investigations of free radical-induced alterations in neocortical synaptosomal membrane protein infrastructure
-
Hensley K, Carney J, Hall N, Shaw W, Butterfield DA. Electron paramagnetic resonance investigations of free radical-induced alterations in neocortical synaptosomal membrane protein infrastructure. Free Radic Biol Med 17: 321-31 (1994).
-
(1994)
Free Radic Biol Med
, vol.17
, pp. 321-31
-
-
Hensley, K.1
Carney, J.2
Hall, N.3
Shaw, W.4
Butterfield, D.A.5
-
118
-
-
0034595888
-
Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats
-
Bickford PC, Gould T, Briederick L, Chadman K, Pollock A, Young D, et al. Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats. Brain Res 866: 211-7 (2000).
-
(2000)
Brain Res
, vol.866
, pp. 211-217
-
-
Bickford, P.C.1
Gould, T.2
Briederick, L.3
Chadman, K.4
Pollock, A.5
Young, D.6
-
119
-
-
0037133283
-
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-α-lipoic acid
-
Liu J, Head E, Gharib AM, Yuan W, Ingersoll RT, Hagen TM, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-α-lipoic acid. Proc Natl Acad Sci USA 99: 2356-61 (2002).
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2356-61
-
-
Liu, J.1
Head, E.2
Gharib, A.M.3
Yuan, W.4
Ingersoll, R.T.5
Hagen, T.M.6
-
120
-
-
60349086658
-
Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease
-
Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, et al. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radic Res 43: 156-64 (2009).
-
(2009)
Free Radic Res
, vol.43
, pp. 156-64
-
-
Siedlak, S.L.1
Casadesus, G.2
Webber, K.M.3
Pappolla, M.A.4
Atwood, C.S.5
Smith, M.A.6
-
121
-
-
0032756213
-
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits
-
Holcomb LA, Gordon MN, Jantzen P, Hsiao K, Duff K, Morgan D. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits. Behav Genet 29: 177-85 (1999).
-
(1999)
Behav Genet
, vol.29
, pp. 177-85
-
-
Holcomb, L.A.1
Gordon, M.N.2
Jantzen, P.3
Hsiao, K.4
Duff, K.5
Morgan, D.6
-
122
-
-
33845442944
-
Chronic dietary α-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice
-
Quinn JF, Bussiere JR, Hammond RS, Montine TJ, Henson E, Jones RE, et al. Chronic dietary α-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 mice. Neurobiol Aging 28: 213-25 (2007).
-
(2007)
Neurobiol Aging
, vol.28
, pp. 213-25
-
-
Quinn, J.F.1
Bussiere, J.R.2
Hammond, R.S.3
Montine, T.J.4
Henson, E.5
Jones, R.E.6
-
123
-
-
0034986275
-
α-Lipoic acid as a new treatment option for Azheimer type dementia
-
Hager K, Marahrens A, Kenklies M, Riederer P, Munch G. α-Lipoic acid as a new treatment option for Azheimer type dementia. Arch Gerontol Geriatr 32: 275-82 (2001).
-
(2001)
Arch Gerontol Geriatr
, vol.32
, pp. 275-82
-
-
Hager, K.1
Marahrens, A.2
Kenklies, M.3
Riederer, P.4
Munch, G.5
-
124
-
-
38449099641
-
α-Lipoic acid as a new treatment option for Alzheimer's disease -- A 48 months follow-up analysis
-
Hager K, Kenklies M, McAfoose J, Engel J, Munch G. α-Lipoic acid as a new treatment option for Alzheimer's disease -- A 48 months follow-up analysis. J Neural Transm Suppl 189-93 (2007).
-
(2007)
J Neural Transm Suppl
, pp. 189-93
-
-
Hager, K.1
Kenklies, M.2
McAfoose, J.3
Engel, J.4
Munch, G.5
-
125
-
-
0033863355
-
Dietary intake and bioavailability of polyphenols
-
Scalbert A, Williamson G. Dietary intake and bioavailability of polyphenols. J Nutr 130: 2073S-2085S (2000).
-
(2000)
J Nutr
, vol.130
-
-
Scalbert, A.1
Williamson, G.2
-
126
-
-
0020626421
-
Flavonoids, a class of natural products of high pharmacological potency
-
Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol 32: 1141-8 (1983).
-
(1983)
Biochem Pharmacol
, vol.32
, pp. 1141-1148
-
-
Havsteen, B.1
-
127
-
-
0028793218
-
Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers
-
Hollman PC, de Vries JH, van Leeuwen SD, Mengelers MJ, Katan MB. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am J Clin Nutr 62: 1276-82 (1995).
-
(1995)
Am J Clin Nutr
, vol.62
, pp. 1276-82
-
-
Hollman, P.C.1
de Vries, J.H.2
van Leeuwen, S.D.3
Mengelers, M.J.4
Katan, M.B.5
-
128
-
-
0033661837
-
Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers
-
Erlund I, Kosonen T, Alfthan G, Maenpaa J, Perttunen K, Kenraali J, et al. Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers. Eur J Clin Pharmacol 56: 545-53 (2000).
-
(2000)
Eur J Clin Pharmacol
, vol.56
, pp. 545-53
-
-
Erlund, I.1
Kosonen, T.2
Alfthan, G.3
Maenpaa, J.4
Perttunen, K.5
Kenraali, J.6
-
129
-
-
0032566518
-
Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver P-glucosidase activity
-
Day AJ, DuPont MS, Ridley S, Rhodes M, Rhodes MJ, Morgan MR, et al. Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver P-glucosidase activity. FEBS Lett 436: 71-5 (1998).
-
(1998)
FEBS Lett
, vol.436
, pp. 71-75
-
-
Day, A.J.1
Dupont, M.S.2
Ridley, S.3
Rhodes, M.4
Rhodes, M.J.5
Morgan, M.R.6
-
130
-
-
17644431778
-
Quercetin gluco-sides interact with the intestinal glucose transport pathway
-
Gee JM, DuPont MS, Rhodes MJ, Johnson IT. Quercetin gluco-sides interact with the intestinal glucose transport pathway. Free Radic Biol Med 25: 19-25 (1998).
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 19-25
-
-
Gee, J.M.1
Dupont, M.S.2
Rhodes, M.J.3
Johnson, I.T.4
-
131
-
-
0033847137
-
Efflux of dietary flavonoid quercetin 4'-P-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2
-
Walgren RA, Karnaky KJ, Lindenmayer GE, Walle T. Efflux of dietary flavonoid quercetin 4'-P-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-2. J Pharmacol Exp Ther 294: 830-6 (2000).
-
(2000)
J Pharmacol Exp Ther
, vol.294
, pp. 830-836
-
-
Walgren, R.A.1
Karnaky, K.J.2
Lindenmayer, G.E.3
Walle, T.4
-
132
-
-
0035865819
-
Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms
-
Ishige K, Schubert D, Sagara Y. Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radic Biol Med 30: 433-46 (2001).
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 433-46
-
-
Ishige, K.1
Schubert, D.2
Sagara, Y.3
-
133
-
-
0028318752
-
The correlation between active oxygens scavenging and antioxidative effects of flavonoids
-
Hanasaki Y, Ogawa S, Fukui S. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic Biol Med 16: 845-50 (1994).
-
(1994)
Free Radic Biol Med
, vol.16
, pp. 845-50
-
-
Hanasaki, Y.1
Ogawa, S.2
Fukui, S.3
-
134
-
-
0031740591
-
Nitric oxide radical scavenging of flavonoids
-
Haenen GR, Bast A. Nitric oxide radical scavenging of flavonoids. Methods Enzymol 301: 490-503 (1999).
-
(1999)
Methods Enzymol
, vol.301
, pp. 490-503
-
-
Haenen, G.R.1
Bast, A.2
-
136
-
-
27744563958
-
Effects of naturally occurring compounds on fibril formation and oxidative stress of P-amyloid
-
Kim H, Park BS, Lee KG, Choi CY, Jang SS, Kim YH, et al. Effects of naturally occurring compounds on fibril formation and oxidative stress of P-amyloid. J Agric Food Chem 53: 8537-41 (2005).
-
(2005)
J Agric Food Chem
, vol.53
, pp. 8537-41
-
-
Kim, H.1
Park, B.S.2
Lee, K.G.3
Choi, C.Y.4
Jang, S.S.5
Kim, Y.H.6
-
137
-
-
0141642253
-
Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: Implications for the prevention and therapeutics of Alzheimer's disease
-
Ono K, Yoshiike Y, Takashima A, Hasegawa K, Naiki H, Yamada M. Potent anti-amyloidogenic and fibril-destabilizing effects of polyphenols in vitro: Implications for the prevention and therapeutics of Alzheimer's disease. J Neurochem 87: 172-81 (2003).
-
(2003)
J Neurochem
, vol.87
, pp. 172-81
-
-
Ono, K.1
Yoshiike, Y.2
Takashima, A.3
Hasegawa, K.4
Naiki, H.5
Yamada, M.6
-
138
-
-
61749103704
-
Protective effect of quercetin in primary neurons against AP(1-42): Relevance to Alzheimer's disease
-
Ansari MA, Abdul HM, Joshi G, Opii WO, Butterfield DA. Protective effect of quercetin in primary neurons against AP(1-42): Relevance to Alzheimer's disease. J Nutr Biochem 20: 269-75 (2009).
-
(2009)
J Nutr Biochem
, vol.20
, pp. 269-75
-
-
Ansari, M.A.1
Abdul, H.M.2
Joshi, G.3
Opii, W.O.4
Butterfield, D.A.5
-
139
-
-
43049176634
-
Health effects of quercetin: From antioxidant to nutraceutical
-
Boots AW, Haenen GR, Bast A. Health effects of quercetin: From antioxidant to nutraceutical. Eur J Pharmacol 585: 325-37 (2008).
-
(2008)
Eur J Pharmacol
, vol.585
, pp. 325-37
-
-
Boots, A.W.1
Haenen, G.R.2
Bast, A.3
-
140
-
-
0035865879
-
Peroxidative metabolism of apigenin and naringenin versus luteolin and quercetin: Glutathione oxidation and conjugation
-
Galati G, Moridani MY, Chan TS, O'Brien PJ. Peroxidative metabolism of apigenin and naringenin versus luteolin and quercetin: Glutathione oxidation and conjugation. Free Radic Biol Med 30: 370-82 (2001).
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 370-82
-
-
Galati, G.1
Moridani, M.Y.2
Chan, T.S.3
O'Brien, P.J.4
-
141
-
-
0037024378
-
Identification of o-quinone/quinone me-thide metabolites of quercetin in a cellular in vitro system
-
Awad HM, Boersma MG, Boeren S, van der Woude H, van Zanden J, van Bladeren PJ, et al. Identification of o-quinone/quinone me-thide metabolites of quercetin in a cellular in vitro system. FEBS Lett 520: 30-4 (2002).
-
(2002)
FEBS Lett
, vol.520
, pp. 30-34
-
-
Awad, H.M.1
Boersma, M.G.2
Boeren, S.3
van der Woude, H.4
van Zanden, J.5
van Bladeren, P.J.6
-
142
-
-
34250777194
-
The quercetin paradox
-
Boots AW, Li H, Schins RP, Duffin R, Heemskerk JW, Bast A, et al. The quercetin paradox. Toxicol Appl Pharmacol 222: 89-96 (2007).
-
(2007)
Toxicol Appl Pharmacol
, vol.222
, pp. 89-96
-
-
Boots, A.W.1
Li, H.2
Schins, R.P.3
Duffin, R.4
Heemskerk, J.W.5
Bast, A.6
-
143
-
-
27744529413
-
The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity
-
Boots AW, Balk JM, Bast A, Haenen GR. The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity. Biochem Biophys Res Commun 338: 923-929 (2005).
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 923-929
-
-
Boots, A.W.1
Balk, J.M.2
Bast, A.3
Haenen, G.R.4
-
144
-
-
0020644145
-
Metabolic fate of [14C] quercetin in the ACI rat
-
Ueno I, Nakano N, Hirono I. Metabolic fate of [14C] quercetin in the ACI rat. Jpn J Exp Med 53: 41-50 (1983).
-
(1983)
Jpn J Exp Med
, vol.53
, pp. 41-50
-
-
Ueno, I.1
Nakano, N.2
Hirono, I.3
-
145
-
-
0037032253
-
Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4'-glucoside
-
Mullen W, Graf BA, Caldwell ST, Hartley RC, Duthie GG, Edwards CA, et al. Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4'-glucoside. J Agric Food Chem 50: 6902-9 (2002).
-
(2002)
J Agric Food Chem
, vol.50
, pp. 6902-6909
-
-
Mullen, W.1
Graf, B.A.2
Caldwell, S.T.3
Hartley, R.C.4
Duthie, G.G.5
Edwards, C.A.6
-
146
-
-
0033954485
-
High-performance liquid chromatographic determination of quercetin and isorhamnetin in rat tissues using P-glucuronidase and acid hydrolysis
-
Morrice PC, Wood SG, Duthie GG. High-performance liquid chromatographic determination of quercetin and isorhamnetin in rat tissues using P-glucuronidase and acid hydrolysis. J Chromatogr B Biomed Sci Appl 738: 413-7 (2000).
-
(2000)
J Chromatogr B Biomed Sci Appl
, vol.738
, pp. 413-417
-
-
Morrice, P.C.1
Wood, S.G.2
Duthie, G.G.3
-
147
-
-
22144495044
-
Tissue distribution of quercetin in rats and pigs
-
de Boer VC, Dihal AA, van der Woude H, Arts IC, Wolffram S, Alink GM, et al. Tissue distribution of quercetin in rats and pigs. J Nutr 135: 1718-25 (2005).
-
(2005)
J Nutr
, vol.135
, pp. 1718-25
-
-
de Boer, V.C.1
Dihal, A.A.2
van der Woude, H.3
Arts, I.C.4
Wolffram, S.5
Alink, G.M.6
-
148
-
-
1242338756
-
Flavonoid permeability across an in situ model of the blood-brain barrier
-
Youdim KA, Qaiser MZ, Begley DJ, Rice-Evans CA, Abbott NJ. Flavonoid permeability across an in situ model of the blood-brain barrier. Free Radic Biol Med 36: 592-604 (2004).
-
(2004)
Free Radic Biol Med
, vol.36
, pp. 592-604
-
-
Youdim, K.A.1
Qaiser, M.Z.2
Begley, D.J.3
Rice-Evans, C.A.4
Abbott, N.J.5
-
149
-
-
0027132062
-
Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells
-
Phang JM, Poore CM, Lopaczynska J, Yeh GC. Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells. Cancer Res 53: 5977-81 (1993).
-
(1993)
Cancer Res
, vol.53
, pp. 5977-81
-
-
Phang, J.M.1
Poore, C.M.2
Lopaczynska, J.3
Yeh, G.C.4
-
150
-
-
0029111458
-
Quercetin not only inhibits P-glycoprotein efflux activity but also inhibits CYP3A isozymes
-
Sarkar MA. Quercetin not only inhibits P-glycoprotein efflux activity but also inhibits CYP3A isozymes. Cancer Chemother Pharmacol 36: 448-50 (1995).
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 448-50
-
-
Sarkar, M.A.1
-
151
-
-
0242695672
-
Resveratrol: From grapevines to mammalian biology
-
Pervaiz S. Resveratrol: From grapevines to mammalian biology. FASEB J 17: 1975-85 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 1975-85
-
-
Pervaiz, S.1
-
152
-
-
0037184675
-
Resveratrol protects against global cerebral ischemic injury in gerbils
-
Wang Q, Xu J, Rottinghaus GE, Simonyi A, Lubahn D, Sun GY, et al. Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res 958: 439-47 (2002).
-
(2002)
Brain Res
, vol.958
, pp. 439-47
-
-
Wang, Q.1
Xu, J.2
Rottinghaus, G.E.3
Simonyi, A.4
Lubahn, D.5
Sun, G.Y.6
-
153
-
-
60249098801
-
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease
-
Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE. Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease. Neurochem Int 54: 111-8 (2009).
-
(2009)
Neurochem Int
, vol.54
, pp. 111-118
-
-
Karuppagounder, S.S.1
Pinto, J.T.2
Xu, H.3
Chen, H.L.4
Beal, M.F.5
Gibson, G.E.6
-
154
-
-
0036667553
-
Inhibition of cancer growth by resveratrol is related to its low bioavailability
-
Asensi M, Medina I, Ortega A, Carretero J, Bano MC, Obrador E, et al. Inhibition of cancer growth by resveratrol is related to its low bioavailability. Free Radic Biol Med 33: 387-98 (2002).
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 387-98
-
-
Asensi, M.1
Medina, I.2
Ortega, A.3
Carretero, J.4
Bano, M.C.5
Obrador, E.6
-
155
-
-
17844393436
-
Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) on adenoma development in the Apc(Min+) mouse and cyclooxygenase-2 in human-derived colon cancer cells
-
Sale S, Tunstall RG, Ruparelia KC, Potter GA, Steward WP, Gescher AJ. Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) on adenoma development in the Apc(Min+) mouse and cyclooxygenase-2 in human-derived colon cancer cells. Int J Cancer 115: 194-201 (2005).
-
(2005)
Int J Cancer
, vol.115
, pp. 194-201
-
-
Sale, S.1
Tunstall, R.G.2
Ruparelia, K.C.3
Potter, G.A.4
Steward, W.P.5
Gescher, A.J.6
-
156
-
-
77950575506
-
AMPK signaling activation by resveratrol modulates amyloid-P peptide metabolism
-
Vingtdeux V, Giliberto L, Zhao H, Chandakkar P, Wu Q, Simon JE, et al. AMPK signaling activation by resveratrol modulates amyloid-P peptide metabolism. J Biol Chem (2010).
-
(2010)
J Biol Chem
-
-
Vingtdeux, V.1
Giliberto, L.2
Zhao, H.3
Chandakkar, P.4
Wu, Q.5
Simon, J.E.6
-
157
-
-
0028845839
-
Antioxidant activity of resveratrol in red wine
-
Miller NJ, Rice-Evans CA. Antioxidant activity of resveratrol in red wine. Clin Chem 41: 1789 (1995).
-
(1995)
Clin Chem
, vol.41
, pp. 1789
-
-
Miller, N.J.1
Rice-Evans, C.A.2
-
158
-
-
27744488160
-
Upregulation of endogenous antioxidants and phase 2 enzymes by the red wine polyphenol, resveratrol in cultured aortic smooth muscle cells leads to cytoprotection against oxidative and electrophilic stress
-
Li Y, Cao Z, Zhu H. Upregulation of endogenous antioxidants and phase 2 enzymes by the red wine polyphenol, resveratrol in cultured aortic smooth muscle cells leads to cytoprotection against oxidative and electrophilic stress. Pharmacol Res 53: 6-15 (2006).
-
(2006)
Pharmacol Res
, vol.53
, pp. 6-15
-
-
Li, Y.1
Cao, Z.2
Zhu, H.3
-
159
-
-
38349053821
-
Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD
-
Robb EL, Page MM, Wiens BE, Stuart JA. Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD. Biochem Biophys Res Commun 367: 406-12 (2008).
-
(2008)
Biochem Biophys Res Commun
, vol.367
, pp. 406-12
-
-
Robb, E.L.1
Page, M.M.2
Wiens, B.E.3
Stuart, J.A.4
-
160
-
-
34247874522
-
Protective effects of piceatannol against P-amyloid-induced neuronal cell death
-
Kim HJ, Lee KW, Lee HJ. Protective effects of piceatannol against P-amyloid-induced neuronal cell death. Ann NY Acad Sci 1095: 473-82 (2007).
-
(2007)
Ann NY Acad Sci
, vol.1095
, pp. 473-82
-
-
Kim, H.J.1
Lee, K.W.2
Lee, H.J.3
-
161
-
-
0037446328
-
Protective effect of resveratrol on P-amyloid-induced oxidative PC12 cell death
-
Jang JH, Surh YJ. Protective effect of resveratrol on P-amyloid-induced oxidative PC12 cell death. Free Radic Biol Med 34: 1100-10 (2003).
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 1100-10
-
-
Jang, J.H.1
Surh, Y.J.2
-
162
-
-
0142195765
-
Synergistic protection of PC 12 cells from P-amyloid toxicity by resveratrol and catechin
-
Conte A, Pellegrini S, Tagliazucchi D. Synergistic protection of PC 12 cells from P-amyloid toxicity by resveratrol and catechin. Brain Res Bull 62: 29-38 (2003).
-
(2003)
Brain Res Bull
, vol.62
, pp. 29-38
-
-
Conte, A.1
Pellegrini, S.2
Tagliazucchi, D.3
-
163
-
-
71249124418
-
Resveratrol inhibits P-amyloid oligomeric cytotoxicity but does not prevent oligomer formation
-
Feng Y, Wang XP, Yang SG, Wang YJ, Zhang X, Du XT, et al. Resveratrol inhibits P-amyloid oligomeric cytotoxicity but does not prevent oligomer formation. Neurotoxicology 30: 986-95 (2009).
-
(2009)
Neurotoxicology
, vol.30
, pp. 986-95
-
-
Feng, Y.1
Wang, X.P.2
Yang, S.G.3
Wang, Y.J.4
Zhang, X.5
Du, X.T.6
-
164
-
-
2542455537
-
Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease
-
Klein WL, Stine WB, Teplow DB. Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease. Neurobiol Aging 25: 569-80 (2004).
-
(2004)
Neurobiol Aging
, vol.25
, pp. 569-80
-
-
Klein, W.L.1
Stine, W.B.2
Teplow, D.B.3
-
165
-
-
33745096194
-
Inhibition of amyloid fibril formation by polyphenols: Structural similarity and aromatic interactions as a common inhibition mechanism
-
Porat Y, Abramowitz A, Gazit E. Inhibition of amyloid fibril formation by polyphenols: Structural similarity and aromatic interactions as a common inhibition mechanism. Chem Biol Drug Des 67: 27-37 (2006).
-
(2006)
Chem Biol Drug Des
, vol.67
, pp. 27-37
-
-
Porat, Y.1
Abramowitz, A.2
Gazit, E.3
-
166
-
-
4444226105
-
Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases
-
Weinreb O, Mandel S, Amit T, Youdim MB. Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases. J Nutr Biochem 15: 506-16 (2004).
-
(2004)
J Nutr Biochem
, vol.15
, pp. 506-16
-
-
Weinreb, O.1
Mandel, S.2
Amit, T.3
Youdim, M.B.4
-
167
-
-
77951829892
-
Curcumin, resveratrol and fla-vonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds
-
Bisht K, Wagner KH, Bulmer AC. Curcumin, resveratrol and fla-vonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds. Toxicology (2009).
-
(2009)
Toxicology
-
-
Bisht, K.1
Wagner, K.H.2
Bulmer, A.C.3
-
168
-
-
34249988863
-
Resveratrol oligomers from Vitis amurensis attenuate P-amyloid-induced oxidative stress in PC12 cells
-
Jang MH, Piao XL, Kim HY, Cho EJ, Baek SH, Kwon SW, et al. Resveratrol oligomers from Vitis amurensis attenuate P-amyloid-induced oxidative stress in PC12 cells. Biol Pharm Bull 30: 1130-4 (2007).
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 1130-1134
-
-
Jang, M.H.1
Piao, X.L.2
Kim, H.Y.3
Cho, E.J.4
Baek, S.H.5
Kwon, S.W.6
-
169
-
-
42949146053
-
Inhibition of cholinesterase and amyloid-P aggregation by resveratrol oligomers from Vitis amurensis
-
Jang MH, Piao XL, Kim JM, Kwon SW, Park JH. Inhibition of cholinesterase and amyloid-P aggregation by resveratrol oligomers from Vitis amurensis. Phytother Res 22: 544-9 (2008).
-
(2008)
Phytother Res
, vol.22
, pp. 544-549
-
-
Jang, M.H.1
Piao, X.L.2
Kim, J.M.3
Kwon, S.W.4
Park, J.H.5
-
170
-
-
27844497059
-
Resveratrol promotes clearance of Alzheimer's disease amyloid-P peptides
-
Marambaud P, Zhao H, Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-P peptides. J Biol Chem 280: 37377-82 (2005).
-
(2005)
J Biol Chem
, vol.280
, pp. 37377-82
-
-
Marambaud, P.1
Zhao, H.2
Davies, P.3
-
171
-
-
0034131044
-
Impaired proteasome function in Alzheimer's disease
-
Keller JN, Hanni KB, Markesbery WR. Impaired proteasome function in Alzheimer's disease. J Neurochem 75: 436-9 (2000).
-
(2000)
J Neurochem
, vol.75
, pp. 436-439
-
-
Keller, J.N.1
Hanni, K.B.2
Markesbery, W.R.3
-
172
-
-
0028979993
-
Amyloid P-protein inhibits ubiquitin-dependent protein degradation in vitro
-
Gregori L, Fuchs C, Figueiredo-Pereira ME, van Nostrand WE, Goldgaber D. Amyloid P-protein inhibits ubiquitin-dependent protein degradation in vitro. J Biol Chem 270: 19702-8 (1995).
-
(1995)
J Biol Chem
, vol.270
, pp. 19702-19708
-
-
Gregori, L.1
Fuchs, C.2
Figueiredo-Pereira, M.E.3
van Nostrand, W.E.4
Goldgaber, D.5
-
173
-
-
33845620279
-
Moderate consumption of Cabernet Sauvignon attenuates AP neuropathology in a mouse model of Alzheimer's disease
-
Wang J, Ho L, Zhao Z, Seror I, Humala N, Dickstein DL, et al. Moderate consumption of Cabernet Sauvignon attenuates AP neuropathology in a mouse model of Alzheimer's disease. FASEB J 20: 2313-20 (2006).
-
(2006)
FASEB J
, vol.20
, pp. 2313-20
-
-
Wang, J.1
Ho, L.2
Zhao, Z.3
Seror, I.4
Humala, N.5
Dickstein, D.L.6
-
174
-
-
0037069290
-
Amount and type of alcohol and risk of dementia: The Copenhagen City Heart Study
-
Truelsen T, Thudium D, Gronbaek M. Amount and type of alcohol and risk of dementia: The Copenhagen City Heart Study. Neurology 59: 1313-9 (2002).
-
(2002)
Neurology
, vol.59
, pp. 1313-1319
-
-
Truelsen, T.1
Thudium, D.2
Gronbaek, M.3
-
175
-
-
0030977937
-
Wine consumption and dementia in the elderly: A prospective community study in the Bordeaux area
-
Orgogozo JM, Dartigues JF, Lafont S, Letenneur L, Commenges D, Salamon R et al. Wine consumption and dementia in the elderly: A prospective community study in the Bordeaux area. Rev Neurol (Paris) 153: 185-92 (1997).
-
(1997)
Rev Neurol (Paris)
, vol.153
, pp. 185-92
-
-
Orgogozo, J.M.1
Dartigues, J.F.2
Lafont, S.3
Letenneur, L.4
Commenges, D.5
Salamon, R.6
-
176
-
-
0031553912
-
Wine may prevent dementia
-
Dorozynski A. Wine may prevent dementia. BMJ 314: 997 (1997).
-
(1997)
BMJ
, vol.314
, pp. 997
-
-
Dorozynski, A.1
-
177
-
-
1842632618
-
Alcohol intake and risk of dementia
-
Luchsinger JA, Tang MX, Siddiqui M, Shea S, Mayeux R. Alcohol intake and risk of dementia. J Am Geriatr Soc 52: 540-6 (2004).
-
(2004)
J Am Geriatr Soc
, vol.52
, pp. 540-546
-
-
Luchsinger, J.A.1
Tang, M.X.2
Siddiqui, M.3
Shea, S.4
Mayeux, R.5
-
178
-
-
46749123053
-
Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease
-
Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, et al. Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease. J Neurosci 28: 6388-92 (2008).
-
(2008)
J Neurosci
, vol.28
, pp. 6388-92
-
-
Wang, J.1
Ho, L.2
Zhao, W.3
Ono, K.4
Rosensweig, C.5
Chen, L.6
-
179
-
-
46749123053
-
Grape-derived polyphenolics prevent AP oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease
-
Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, et al. Grape-derived polyphenolics prevent AP oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease. J Neurosci 28: 6388-92 (2008).
-
(2008)
J Neurosci
, vol.28
, pp. 6388-92
-
-
Wang, J.1
Ho, L.2
Zhao, W.3
Ono, K.4
Rosensweig, C.5
Chen, L.6
-
180
-
-
57749112087
-
Effects of grape seed-derived polyphenols on amyloid P-protein self-assembly and cytotoxicity
-
Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, et al. Effects of grape seed-derived polyphenols on amyloid P-protein self-assembly and cytotoxicity. J Biol Chem 283: 32176-87 (2008).
-
(2008)
J Biol Chem
, vol.283
, pp. 32176-87
-
-
Ono, K.1
Condron, M.M.2
Ho, L.3
Wang, J.4
Zhao, W.5
Pasinetti, G.M.6
-
181
-
-
36248975293
-
SIRT1 transgenic mice show phenotypes resembling calo rie restriction
-
Bordone L, Cohen D, Robinson A, Motta MC, van Veen E, Czopik A, et al. SIRT1 transgenic mice show phenotypes resembling calo rie restriction. Aging Cell 6: 759-67 (2007).
-
(2007)
Aging Cell
, vol.6
, pp. 759-67
-
-
Bordone, L.1
Cohen, D.2
Robinson, A.3
Motta, M.C.4
van Veen, E.5
Czopik, A.6
-
182
-
-
33845938278
-
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging
-
Hyun DH, Emerson SS, Jo DG, Mattson MP, de Cabo R. Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging. Proc Natl Acad Sci USA 103: 19908-12 (2006).
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 19908-12
-
-
Hyun, D.H.1
Emerson, S.S.2
Jo, D.G.3
Mattson, M.P.4
de Cabo, R.5
-
183
-
-
0037465541
-
Will caloric restriction and folate protect against AD and PD?
-
Mattson MP. Will caloric restriction and folate protect against AD and PD? Neurology 60: 690-5 (2003).
-
(2003)
Neurology
, vol.60
, pp. 690-695
-
-
Mattson, M.P.1
-
184
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410: 227-30 (2001).
-
(2001)
Nature
, vol.410
, pp. 227-30
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
185
-
-
22844438667
-
Crosstalk between p53 and FOXO transcription factors
-
You H, Mak TW. Crosstalk between p53 and FOXO transcription factors. Cell Cycle 4: 37-8 (2005).
-
(2005)
Cell Cycle
, vol.4
, pp. 37-38
-
-
You, H.1
Mak, T.W.2
-
186
-
-
16844375290
-
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
-
Parker JA, Arango M, Abderrahmane S, Lambert E, Tourette C, Catoire H, et al. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat Genet 37: 349-50 (2005).
-
(2005)
Nat Genet
, vol.37
, pp. 349-50
-
-
Parker, J.A.1
Arango, M.2
Abderrahmane, S.3
Lambert, E.4
Tourette, C.5
Catoire, H.6
-
187
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305: 390-2 (2004).
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
-
188
-
-
28844474597
-
SIRT1 protects against microglia-dependent amyloid-P toxicity through inhibiting NF-kB signaling
-
Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S, et al. SIRT1 protects against microglia-dependent amyloid-P toxicity through inhibiting NF-kB signaling. J Biol Chem 280: 40364-74 (2005).
-
(2005)
J Biol Chem
, vol.280
, pp. 40364-74
-
-
Chen, J.1
Zhou, Y.2
Mueller-Steiner, S.3
Chen, L.F.4
Kwon, H.5
Yi, S.6
-
189
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegen-eration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, et al. SIRT1 deacetylase protects against neurodegen-eration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 26: 3169-79 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 3169-79
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
-
190
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
-
Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, et al. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem 281: 21745-54 (2006).
-
(2006)
J Biol Chem
, vol.281
, pp. 21745-54
-
-
Qin, W.1
Yang, T.2
Ho, L.3
Zhao, Z.4
Wang, J.5
Chen, L.6
-
191
-
-
0141719702
-
Small molecule activators of sirtuins extend Sac-charomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, et al. Small molecule activators of sirtuins extend Sac-charomyces cerevisiae lifespan. Nature 425: 191-6 (2003).
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
-
192
-
-
22744450382
-
Toward a unified theory of caloric restriction and longevity regulation
-
Sinclair DA. Toward a unified theory of caloric restriction and longevity regulation. Mech Ageing Dev 126: 987-1002 (2005).
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 987-1002
-
-
Sinclair, D.A.1
-
193
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430: 686-9 (2004).
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
-
194
-
-
4344590155
-
Small molecules that regulate lifespan: Evidence for xenohormesis
-
Lamming DW, Wood JG, Sinclair DA. Small molecules that regulate lifespan: Evidence for xenohormesis. Mol Microbiol 53: 1003-9 (2004).
-
(2004)
Mol Microbiol
, vol.53
, pp. 1003-1009
-
-
Lamming, D.W.1
Wood, J.G.2
Sinclair, D.A.3
-
195
-
-
68949206606
-
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by α-synuclein or amy-loid-P(1-42) peptide
-
Albani D, Polito L, Batelli S, de Mauro S, Fracasso C, Martelli G, et al. The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by α-synuclein or amy-loid-P(1-42) peptide. J Neurochem 110: 1445-56 (2009).
-
(2009)
J Neurochem
, vol.110
, pp. 1445-56
-
-
Albani, D.1
Polito, L.2
Batelli, S.3
de Mauro, S.4
Fracasso, C.5
Martelli, G.6
-
196
-
-
33747886389
-
Resveratrol -- A boon for treating Alzheimer's disease?
-
Anekonda TS. Resveratrol -- A boon for treating Alzheimer's disease? Brain Res Rev 52: 316-26 (2006).
-
(2006)
Brain Res Rev
, vol.52
, pp. 316-26
-
-
Anekonda, T.S.1
-
197
-
-
55549096745
-
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
-
Lan F, Cacicedo JM, Ruderman N, Ido Y. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. J Biol Chem 283: 27628-35 (2008).
-
(2008)
J Biol Chem
, vol.283
, pp. 27628-35
-
-
Lan, F.1
Cacicedo, J.M.2
Ruderman, N.3
Ido, Y.4
-
198
-
-
20444444649
-
Mechanism of human SIRT1 activation by resveratrol
-
Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem 280: 17187-95 (2005).
-
(2005)
J Biol Chem
, vol.280
, pp. 17187-95
-
-
Borra, M.T.1
Smith, B.C.2
Denu, J.M.3
-
199
-
-
34249846128
-
Resveratrol stimulates AMP kinase activity in neurons
-
Dasgupta B, Milbrandt J. Resveratrol stimulates AMP kinase activity in neurons. Proc Natl Acad Sci USA 104: 7217-22 (2007).
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7217-22
-
-
Dasgupta, B.1
Milbrandt, J.2
-
200
-
-
77249119143
-
AMPK-deficient mice are resistant to the metabolic effects of resveratrol
-
Um JH, Park SJ, Kang H, Yang S, Foretz M, McBurney MW, et al. AMPK-deficient mice are resistant to the metabolic effects of resveratrol. Diabetes (2009).
-
(2009)
Diabetes
-
-
Um, J.H.1
Park, S.J.2
Kang, H.3
Yang, S.4
Foretz, M.5
McBurney, M.W.6
-
201
-
-
0034096319
-
Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study
-
Ganguli M, Chandra V, Kamboh MI, Johnston JM, Dodge HH, Thelma BK, et al. Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study. Arch Neurol 57: 824-30 (2000).
-
(2000)
Arch Neurol
, vol.57
, pp. 824-30
-
-
Ganguli, M.1
Chandra, V.2
Kamboh, M.I.3
Johnston, J.M.4
Dodge, H.H.5
Thelma, B.K.6
-
202
-
-
79959939986
-
Naturally occurring phytochemicals for the prevention of Alzheimer's disease
-
Kim J, Lee HJ, Lee KW. Naturally occurring phytochemicals for the prevention of Alzheimer's disease. J Neurochem (2009).
-
(2009)
J Neurochem
-
-
Kim, J.1
Lee, H.J.2
Lee, K.W.3
-
203
-
-
0024652076
-
Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals
-
Zhao BL, Li XJ, He RG, Cheng SJ, Xin WJ. Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals. Cell Biophys 14: 175-85 (1989).
-
(1989)
Cell Biophys
, vol.14
, pp. 175-85
-
-
Zhao, B.L.1
Li, X.J.2
He, R.G.3
Cheng, S.J.4
Xin, W.J.5
-
204
-
-
29044433921
-
Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by cur-cumin and its analogues
-
Wei QY, Chen WF, Zhou B, Yang L, Liu ZL. Inhibition of lipid peroxidation and protein oxidation in rat liver mitochondria by cur-cumin and its analogues. Biochim Biophys Acta 1760: 70-7 (2006).
-
(2006)
Biochim Biophys Acta
, vol.1760
, pp. 70-77
-
-
Wei, Q.Y.1
Chen, W.F.2
Zhou, B.3
Yang, L.4
Liu, Z.L.5
-
205
-
-
0027270278
-
Inhibition of 8-hydroxydeoxyguanosine formation by curcumin in mouse fibroblast cells
-
Shih CA, Lin JK. Inhibition of 8-hydroxydeoxyguanosine formation by curcumin in mouse fibroblast cells. Carcinogenesis 14: 709-12 (1993).
-
(1993)
Carcinogenesis
, vol.14
, pp. 709-12
-
-
Shih, C.A.1
Lin, J.K.2
-
206
-
-
4644275696
-
Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models
-
discussion 443-9
-
Baum L, Ng A. Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models. J Alzheimers Dis 6: 367-77; discussion 443-9 (2004).
-
(2004)
J Alzheimers Dis
, vol.6
, pp. 367-77
-
-
Baum, L.1
Ng, A.2
-
207
-
-
67650705731
-
Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT)
-
Ishrat T, Hoda MN, Khan MB, Yousuf S, Ahmad M, Khan MM, et al. Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT). Eur Neuropsychopharmacol 19: 636-47 (2009).
-
(2009)
Eur Neuropsychopharmacol
, vol.19
, pp. 636-47
-
-
Ishrat, T.1
Hoda, M.N.2
Khan, M.B.3
Yousuf, S.4
Ahmad, M.5
Khan, M.M.6
-
208
-
-
34248186574
-
Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element
-
Nishinaka T, Ichijo Y, Ito M, Kimura M, Katsuyama M, Iwata K, et al. Curcumin activates human glutathione S-transferase P1 expression through antioxidant response element. Toxicol Lett 170: 238-47 (2007).
-
(2007)
Toxicol Lett
, vol.170
, pp. 238-47
-
-
Nishinaka, T.1
Ichijo, Y.2
Ito, M.3
Kimura, M.4
Katsuyama, M.5
Iwata, K.6
-
209
-
-
56449129616
-
Cellular stress response: A novel target for chemopre-vention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity
-
Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bel-lia F, et al. Cellular stress response: A novel target for chemopre-vention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochem Res 33: 2444-71 (2008).
-
(2008)
Neurochem Res
, vol.33
, pp. 2444-71
-
-
Calabrese, V.1
Cornelius, C.2
Mancuso, C.3
Pennisi, G.4
Calafato, S.5
Bel-Lia, F.6
-
210
-
-
54949107786
-
Curcumin and the cellular stress response in free radical-related diseases
-
Calabrese V, Bates TE, Mancuso C, Cornelius C, Ventimiglia B, Cambria MT, et al. Curcumin and the cellular stress response in free radical-related diseases. Mol Nutr Food Res 52: 1062-73 (2008).
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 1062-73
-
-
Calabrese, V.1
Bates, T.E.2
Mancuso, C.3
Cornelius, C.4
Ventimiglia, B.5
Cambria, M.T.6
-
211
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci 21: 8370-7 (2001).
-
(2001)
J Neurosci
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
212
-
-
0035686083
-
Phenolic anti-inflammatory antioxidant reversal of AP-induced cognitive deficits and neuropathology
-
Frautschy SA, Hu W, Kim P, Miller SA, Chu T, Harris-White ME, et al. Phenolic anti-inflammatory antioxidant reversal of AP-induced cognitive deficits and neuropathology. Neurobiol Aging 22: 993-1005 (2001).
-
(2001)
Neurobiol Aging
, vol.22
, pp. 993-1005
-
-
Frautschy, S.A.1
Hu, W.2
Kim, P.3
Miller, S.A.4
Chu, T.5
Harris-White, M.E.6
-
213
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for Alzheimer's P-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Naiki H, Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer's P-amyloid fibrils in vitro. J Neurosci Res 75: 742-50 (2004).
-
(2004)
J Neurosci Res
, vol.75
, pp. 742-50
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
214
-
-
20044370990
-
Curcumin inhibits formation of amyloid P oligomers and fibrils, binds plaques, and reduces amyloid in vivo
-
Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambe-gaokar SS, et al. Curcumin inhibits formation of amyloid P oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem 280: 5892-901 (2005).
-
(2005)
J Biol Chem
, vol.280
, pp. 5892-901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
Ubeda, O.J.4
Simmons, M.R.5
Ambe-Gaokar, S.S.6
-
215
-
-
34547451145
-
Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model
-
Garcia-Alloza M, Borrelli LA, Rozkalne A, Hyman BT, Bacskai BJ. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J Neurochem 102: 1095-104 (2007).
-
(2007)
J Neurochem
, vol.102
, pp. 1095-104
-
-
Garcia-Alloza, M.1
Borrelli, L.A.2
Rozkalne, A.3
Hyman, B.T.4
Bacskai, B.J.5
-
216
-
-
38349131641
-
Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease
-
Baum L, Lam CW, Cheung SK, Kwok T, Lui V, Tsoh J, et al. Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease. J Clin Psy-chopharmacol 28: 110-3 (2008).
-
(2008)
J Clin Psy-chopharmacol
, vol.28
, pp. 110-113
-
-
Baum, L.1
Lam, C.W.2
Cheung, S.K.3
Kwok, T.4
Lui, V.5
Tsoh, J.6
-
217
-
-
9744229172
-
Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor
-
Giri RK, Rajagopal V, Kalra VK. Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor. J Neurochem 91: 1199-210 (2004).
-
(2004)
J Neurochem
, vol.91
, pp. 1199-210
-
-
Giri, R.K.1
Rajagopal, V.2
Kalra, V.K.3
-
218
-
-
0038121053
-
Tea catechins and polyphenols: Health effects, metabolism, and antioxidant functions
-
Higdon JV, Frei B. Tea catechins and polyphenols: Health effects, metabolism, and antioxidant functions. Crit Rev Food Sci Nutr 43: 89-143 (2003).
-
(2003)
Crit Rev Food Sci Nutr
, vol.43
, pp. 89-143
-
-
Higdon, J.V.1
Frei, B.2
-
219
-
-
20944444111
-
Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway
-
Mandel SA, Avramovich-Tirosh Y, Reznichenko L, Zheng H, Weinreb O, Amit T, et al. Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway. Neu-rosignals 14: 46-60 (2005).
-
(2005)
Neu-rosignals
, vol.14
, pp. 46-60
-
-
Mandel, S.A.1
Avramovich-Tirosh, Y.2
Reznichenko, L.3
Zheng, H.4
Weinreb, O.5
Amit, T.6
-
220
-
-
0034851553
-
Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration
-
Levites Y, Weinreb O, Maor G, Youdim MB, Mandel S. Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration. J Neurochem 78: 1073-82 (2001).
-
(2001)
J Neurochem
, vol.78
, pp. 1073-82
-
-
Levites, Y.1
Weinreb, O.2
Maor, G.3
Youdim, M.B.4
Mandel, S.5
-
221
-
-
34250753928
-
Activation of endothelial nitric oxide synthase by dietary isoflavones: Role of NO in Nrf2-mediated antioxidant gene expression
-
Mann GE, Rowlands DJ, Li FY, de Winter P, Siow RC. Activation of endothelial nitric oxide synthase by dietary isoflavones: Role of NO in Nrf2-mediated antioxidant gene expression. Cardiovasc Res 75: 261-74 (2007).
-
(2007)
Cardiovasc Res
, vol.75
, pp. 261-74
-
-
Mann, G.E.1
Rowlands, D.J.2
Li, F.Y.3
de Winter, P.4
Siow, R.C.5
-
222
-
-
0030582664
-
Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes
-
Guo Q, Zhao B, Li M, Shen S, Xin W. Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochim Biophys Acta 1304: 210-22 (1996).
-
(1996)
Biochim Biophys Acta
, vol.1304
, pp. 210-22
-
-
Guo, Q.1
Zhao, B.2
Li, M.3
Shen, S.4
Xin, W.5
-
223
-
-
0029995757
-
Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical
-
Nanjo F, Goto K, Seto R, Suzuki M, Sakai M, Hara Y. Scavenging effects of tea catechins and their derivatives on 1,1-diphenyl-2-picrylhydrazyl radical. Free Radic Biol Med 21: 895-902 (1996).
-
(1996)
Free Radic Biol Med
, vol.21
, pp. 895-902
-
-
Nanjo, F.1
Goto, K.2
Seto, R.3
Suzuki, M.4
Sakai, M.5
Hara, Y.6
-
224
-
-
0029146507
-
Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants
-
Salah N, Miller NJ, Paganga G, Tijburg L, Bolwell GP, Rice-Evans C. Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch Biochem Biophys 322: 339-46 (1995).
-
(1995)
Arch Biochem Biophys
, vol.322
, pp. 339-46
-
-
Salah, N.1
Miller, N.J.2
Paganga, G.3
Tijburg, L.4
Bolwell, G.P.5
Rice-Evans, C.6
-
225
-
-
33644949188
-
Neuroprotective effects of green and black teas and their catechin gallate esters against P-amyloid-induced toxicity
-
Bastianetto S, Yao ZX, Papadopoulos V, Quirion R. Neuroprotective effects of green and black teas and their catechin gallate esters against P-amyloid-induced toxicity. Eur J Neurosci 23: 55-64 (2006).
-
(2006)
Eur J Neurosci
, vol.23
, pp. 55-64
-
-
Bastianetto, S.1
Yao, Z.X.2
Papadopoulos, V.3
Quirion, R.4
-
226
-
-
33750513363
-
Catechin and epi-catechin from Smilacis chinae rhizome protect cultured rat cortical neurons against amyloid-P protein (25-35)-induced neurotoxicity through inhibition of cytosolic calcium elevation
-
Ban JY, Jeon SY, Bae K, Song KS, Seong YH. Catechin and epi-catechin from Smilacis chinae rhizome protect cultured rat cortical neurons against amyloid-P protein (25-35)-induced neurotoxicity through inhibition of cytosolic calcium elevation. Life Sci 79: 2251-9 (2006).
-
(2006)
Life Sci
, vol.79
, pp. 2251-2259
-
-
Ban, J.Y.1
Jeon, S.Y.2
Bae, K.3
Song, K.S.4
Seong, Y.H.5
-
227
-
-
60349116815
-
Comparative neuroprotective properties of stilbene and catechin analogs: Action via a plasma membrane receptor site?
-
Bastianetto S, Dumont Y, Han Y, Quirion R. Comparative neuroprotective properties of stilbene and catechin analogs: Action via a plasma membrane receptor site? CNS Neurosci Ther 15: 76-83 (2009).
-
(2009)
CNS Neurosci Ther
, vol.15
, pp. 76-83
-
-
Bastianetto, S.1
Dumont, Y.2
Han, Y.3
Quirion, R.4
-
228
-
-
0038661168
-
Neuroprotection and neurorescue against AP toxicity and PKC-dependent release of non-amyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate
-
Levites Y, Amit T, Mandel S, Youdim MB. Neuroprotection and neurorescue against AP toxicity and PKC-dependent release of non-amyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate. FASEB J 17: 952-4 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 952-954
-
-
Levites, Y.1
Amit, T.2
Mandel, S.3
Youdim, M.B.4
-
229
-
-
25444500410
-
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice
-
Rezai-Zadeh K, Shytle D, Sun N, Mori T, Hou H, Jeanniton D, et al. Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. J Neurosci 25: 8807-14 (2005).
-
(2005)
J Neurosci
, vol.25
, pp. 8807-14
-
-
Rezai-Zadeh, K.1
Shytle, D.2
Sun, N.3
Mori, T.4
Hou, H.5
Jeanniton, D.6
-
230
-
-
44249116000
-
Green tea epigallocatechin-3-gallate (EGCG) reduces P-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice
-
Rezai-Zadeh K, Arendash GW, Hou H, Fernandez F, Jensen M, Runfeldt M, et al. Green tea epigallocatechin-3-gallate (EGCG) reduces P-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice. Brain Res 1214: 177-87 (2008).
-
(2008)
Brain Res
, vol.1214
, pp. 177-87
-
-
Rezai-Zadeh, K.1
Arendash, G.W.2
Hou, H.3
Fernandez, F.4
Jensen, M.5
Runfeldt, M.6
-
231
-
-
44249109772
-
Green tea catechins prevent cognitive deficits caused by AP(1-40) in rats
-
Haque AM, Hashimoto M, Katakura M, Hara Y, Shido O. Green tea catechins prevent cognitive deficits caused by AP(1-40) in rats. J Nutr Biochem 19: 619-26 (2008).
-
(2008)
J Nutr Biochem
, vol.19
, pp. 619-26
-
-
Haque, A.M.1
Hashimoto, M.2
Katakura, M.3
Hara, Y.4
Shido, O.5
-
232
-
-
54249143535
-
Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: Special reference to epigallocatechin gallate (EGCG)
-
Mandel SA, Amit T, Kalfon L, Reznichenko L, Weinreb O, Youdim MB. Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: Special reference to epigallocatechin gallate (EGCG). J Alzheimers Dis 15: 211-22 (2008).
-
(2008)
J Alzheimers Dis
, vol.15
, pp. 211-22
-
-
Mandel, S.A.1
Amit, T.2
Kalfon, L.3
Reznichenko, L.4
Weinreb, O.5
Youdim, M.B.6
-
233
-
-
33744465230
-
PKC8 increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice
-
Choi DS, Wang D, Yu GQ, Zhu G, Kharazia VN, Paredes JP, et al. PKC8 increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice. Proc Natl Acad Sci USA 103: 8215-20 (2006).
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8215-20
-
-
Choi, D.S.1
Wang, D.2
Yu, G.Q.3
Zhu, G.4
Kharazia, V.N.5
Paredes, J.P.6
-
234
-
-
33644858479
-
Green tea consumption and cognitive function: A cross-sectional study from the Tsurugaya Project 1
-
Kuriyama S, Hozawa A, Ohmori K, Shimazu T, Matsui T, Ebihara S, et al. Green tea consumption and cognitive function: A cross-sectional study from the Tsurugaya Project 1. Am J Clin Nutr 83: 355-61 (2006).
-
(2006)
Am J Clin Nutr
, vol.83
, pp. 355-61
-
-
Kuriyama, S.1
Hozawa, A.2
Ohmori, K.3
Shimazu, T.4
Matsui, T.5
Ebihara, S.6
-
235
-
-
33748642765
-
Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: The Ohsaki study
-
Kuriyama S, Shimazu T, Ohmori K, Kikuchi N, Nakaya N, Nishino Y, et al. Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan: The Ohsaki study. JAMA 296: 1255-65 (2006).
-
(2006)
JAMA
, vol.296
, pp. 1255-65
-
-
Kuriyama, S.1
Shimazu, T.2
Ohmori, K.3
Kikuchi, N.4
Nakaya, N.5
Nishino, Y.6
-
236
-
-
0037090246
-
Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake
-
Checkoway H, Powers K, Smith-Weller T, Franklin GM, Long-streth WT, Swanson PD. Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake. Am J Epidemiol 155: 732-8 (2002).
-
(2002)
Am J Epidemiol
, vol.155
, pp. 732-738
-
-
Checkoway, H.1
Powers, K.2
Smith-Weller, T.3
Franklin, G.M.4
Long-Streth, W.T.5
Swanson, P.D.6
-
237
-
-
38049053106
-
Coffee and tea consumption and the risk of Parkinson's disease
-
Hu G, Bidel S, Jousilahti P, Antikainen R, Tuomilehto J. Coffee and tea consumption and the risk of Parkinson's disease. Mov Disord 22: 2242-8 (2007).
-
(2007)
Mov Disord
, vol.22
, pp. 2242-2248
-
-
Hu, G.1
Bidel, S.2
Jousilahti, P.3
Antikainen, R.4
Tuomilehto, J.5
-
238
-
-
0036264981
-
Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture systems in vitro: Structure-activity studies
-
Kanski J, Aksenova M, Stoyanova A, Butterfield DA. Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture systems in vitro: Structure-activity studies. J Nutr Biochem 13: 273-81 (2002).
-
(2002)
J Nutr Biochem
, vol.13
, pp. 273-81
-
-
Kanski, J.1
Aksenova, M.2
Stoyanova, A.3
Butterfield, D.A.4
-
239
-
-
0037181328
-
Antioxidant properties of ferulic acid and its related compounds
-
Kikuzaki H, Hisamoto M, Hirose K, Akiyama K, Taniguchi H. Antioxidant properties of ferulic acid and its related compounds. J Agric Food Chem 50: 2161-8 (2002).
-
(2002)
J Agric Food Chem
, vol.50
, pp. 2161-2168
-
-
Kikuzaki, H.1
Hisamoto, M.2
Hirose, K.3
Akiyama, K.4
Taniguchi, H.5
-
240
-
-
13644265462
-
Ferulic acid ethyl ester protects neurons against amyloid P- peptide(1-42)-induced oxidative stress and neurotoxicity: Relationship to antioxidant activity
-
Sultana R, Ravagna A, Mohmmad-Abdul H, Calabrese V, Butter-Field DA. Ferulic acid ethyl ester protects neurons against amyloid P- peptide(1-42)-induced oxidative stress and neurotoxicity: Relationship to antioxidant activity. J Neurochem 92: 749-58 (2005).
-
(2005)
J Neurochem
, vol.92
, pp. 749-58
-
-
Sultana, R.1
Ravagna, A.2
Mohmmad-Abdul, H.3
Calabrese, V.4
Butter-Field, D.A.5
-
241
-
-
31744434516
-
In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): Insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders
-
Joshi G, Perluigi M, Sultana R, Agrippino R, Calabrese V, Butter-field DA. In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe(2+)/H(2)O(2): Insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders. Neurochem Int 48: 318-27 (2006).
-
(2006)
Neurochem Int
, vol.48
, pp. 318-27
-
-
Joshi, G.1
Perluigi, M.2
Sultana, R.3
Agrippino, R.4
Calabrese, V.5
Butter-Field, D.A.6
-
242
-
-
33746415658
-
In vivo protective effects of ferulic acid ethyl ester against amyloid-P peptide 1-42-induced oxidative stress
-
Perluigi M, Joshi G, Sultana R, Calabrese V, De Marco C, Coccia R et al. In vivo protective effects of ferulic acid ethyl ester against amyloid-P peptide 1-42-induced oxidative stress. J Neurosci Res 84: 418-26 (2006).
-
(2006)
J Neurosci Res
, vol.84
, pp. 418-26
-
-
Perluigi, M.1
Joshi, G.2
Sultana, R.3
Calabrese, V.4
de Marco, C.5
Coccia, R.6
-
243
-
-
4544379968
-
Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress
-
Scapagnini G, Butterfield DA, Colombrita C, Sultana R, Pascale A, Calabrese V. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal 6: 811-8 (2004).
-
(2004)
Antioxid Redox Signal
, vol.6
, pp. 811-818
-
-
Scapagnini, G.1
Butterfield, D.A.2
Colombrita, C.3
Sultana, R.4
Pascale, A.5
Calabrese, V.6
-
244
-
-
0035866060
-
P-Amyloid stimulation of microglia and monocytes results in TNFa-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
-
Combs CK, Karlo JC, Kao SC, Landreth GE. P-Amyloid stimulation of microglia and monocytes results in TNFa-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. J Neurosci 21: 1179-88 (2001).
-
(2001)
J Neurosci
, vol.21
, pp. 1179-88
-
-
Combs, C.K.1
Karlo, J.C.2
Kao, S.C.3
Landreth, G.E.4
-
245
-
-
0032473596
-
Amyloid-P peptide activates cultured astrocytes: Morphological alterations, cytokine induction and nitric oxide release
-
Hu J, Akama KT, Krafft GA, Chromy BA, van Eldik LJ. Amyloid-P peptide activates cultured astrocytes: Morphological alterations, cytokine induction and nitric oxide release. Brain Res 785: 195-206 (1998).
-
(1998)
Brain Res
, vol.785
, pp. 195-206
-
-
Hu, J.1
Akama, K.T.2
Krafft, G.A.3
Chromy, B.A.4
van Eldik, L.J.5
-
246
-
-
0036166634
-
Syntheses of ferulic acid derivatives and their suppressive effects on cyclooxygenase-2 promoter activity
-
Hosoda A, Ozaki Y, Kashiwada A, Mutoh M, Wakabayashi K, Mizuno K, et al. Syntheses of ferulic acid derivatives and their suppressive effects on cyclooxygenase-2 promoter activity. Bioorg Med Chem 10: 1189-96 (2002).
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 1189-96
-
-
Hosoda, A.1
Ozaki, Y.2
Kashiwada, A.3
Mutoh, M.4
Wakabayashi, K.5
Mizuno, K.6
-
247
-
-
0034739324
-
Suppressive effects of novel ferulic acid derivatives on cellular responses induced by phorbol ester, and by combined lipopolysaccharide and interferon-y
-
Murakami A, Kadota M, Takahashi D, Taniguchi H, Nomura E, Hosoda A, et al. Suppressive effects of novel ferulic acid derivatives on cellular responses induced by phorbol ester, and by combined lipopolysaccharide and interferon-y. Cancer Lett 157: 77-85 (2000).
-
(2000)
Cancer Lett
, vol.157
, pp. 77-85
-
-
Murakami, A.1
Kadota, M.2
Takahashi, D.3
Taniguchi, H.4
Nomura, E.5
Hosoda, A.6
-
248
-
-
0008881566
-
The heme oxygenase system and its functions in the brain
-
Maines MD. The heme oxygenase system and its functions in the brain. Cell Mol Biol (Noisy-le-grand) 46: 573-85 (2000).
-
(2000)
Cell Mol Biol (Noisy-le-grand)
, vol.46
, pp. 573-85
-
-
Maines, M.D.1
-
249
-
-
4544327666
-
Redox regulation in neurodegeneration and longevity: Role of the heme oxygenase and HSP70 systems in brain stress tolerance
-
Calabrese V, Stella AM, Butterfield DA, Scapagnini G. Redox regulation in neurodegeneration and longevity: Role of the heme oxygenase and HSP70 systems in brain stress tolerance. Antioxid Redox Signal 6: 895-913 (2004).
-
(2004)
Antioxid Redox Signal
, vol.6
, pp. 895-913
-
-
Calabrese, V.1
Stella, A.M.2
Butterfield, D.A.3
Scapagnini, G.4
-
250
-
-
0347991813
-
Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: A nutritional approach
-
Calabrese V, Scapagnini G, Colombrita C, Ravagna A, Pennisi G, Giuffrida Stella AM, et al. Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: A nutritional approach. Amino Acids 25: 437-44 (2003).
-
(2003)
Amino Acids
, vol.25
, pp. 437-44
-
-
Calabrese, V.1
Scapagnini, G.2
Colombrita, C.3
Ravagna, A.4
Pennisi, G.5
Giuffrida Stella, A.M.6
-
251
-
-
0033793044
-
Heme oxygenase-1: Role in brain aging and neurodegeneration
-
Schipper HM. Heme oxygenase-1: Role in brain aging and neurodegeneration. Exp Gerontol 35: 821-30 (2000).
-
(2000)
Exp Gerontol
, vol.35
, pp. 821-30
-
-
Schipper, H.M.1
-
252
-
-
0025172696
-
'Ischemic tolerance' phenomenon found in the brain
-
Kitagawa K, Matsumoto M, Tagaya M, Hata R, Ueda H, Niinobe M, et al. 'Ischemic tolerance' phenomenon found in the brain. Brain Res 528: 21-4 (1990).
-
(1990)
Brain Res
, vol.528
, pp. 21-24
-
-
Kitagawa, K.1
Matsumoto, M.2
Tagaya, M.3
Hata, R.4
Ueda, H.5
Niinobe, M.6
-
253
-
-
0024431368
-
Transient hyperthermia protects against subsequent forebrain ischemic cell damage in the rat
-
Chopp M, Chen H, Ho KL, Dereski MO, Brown E, Hetzel FW, et al. Transient hyperthermia protects against subsequent forebrain ischemic cell damage in the rat. Neurology 39: 1396-8 (1989).
-
(1989)
Neurology
, vol.39
, pp. 1396-1398
-
-
Chopp, M.1
Chen, H.2
Ho, K.L.3
Dereski, M.O.4
Brown, E.5
Hetzel, F.W.6
-
254
-
-
0034986151
-
Protection against P-amyloid peptide toxicity in vivo with long-term administration of ferulic acid
-
Yan JJ, Cho JY, Kim HS, Kim KL, Jung JS, Huh SO, et al. Protection against P-amyloid peptide toxicity in vivo with long-term administration of ferulic acid. Br J Pharmacol 133: 89-96 (2001).
-
(2001)
Br J Pharmacol
, vol.133
, pp. 89-96
-
-
Yan, J.J.1
Cho, J.Y.2
Kim, H.S.3
Kim, K.L.4
Jung, J.S.5
Huh, S.O.6
-
255
-
-
0031942410
-
Regional membrane phospholipid alterations in Alzheimer's disease
-
Prasad MR, Lovell MA, Yatin M, Dhillon H, Markesbery WR. Regional membrane phospholipid alterations in Alzheimer's disease. Neurochem Res 23: 81-8 (1998).
-
(1998)
Neurochem Res
, vol.23
, pp. 81-88
-
-
Prasad, M.R.1
Lovell, M.A.2
Yatin, M.3
Dhillon, H.4
Markesbery, W.R.5
-
256
-
-
20444451750
-
Protection against amyloid P-peptide (1-42)-induced loss of phospholipid asymmetry in synaptosomal membranes by tricyclodecan-9-xanthogenate (D609) and ferulic acid ethyl ester: Implications for Alzheimer's disease
-
Mohmmad Abdul H, Butterfield DA. Protection against amyloid P-peptide (1-42)-induced loss of phospholipid asymmetry in synaptosomal membranes by tricyclodecan-9-xanthogenate (D609) and ferulic acid ethyl ester: Implications for Alzheimer's disease. Bio-chim Biophys Acta 1741: 140-8 (2005).
-
(2005)
Bio-chim Biophys Acta
, vol.1741
, pp. 140-148
-
-
Mohmmad Abdul, H.1
Butterfield, D.A.2
-
257
-
-
42949132291
-
Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates
-
Fang L, Kraus B, Lehmann J, Heilmann J, Zhang Y, Decker M. Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates. Bioorg Med Chem Lett 18: 2905-9 (2008).
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 2905-2909
-
-
Fang, L.1
Kraus, B.2
Lehmann, J.3
Heilmann, J.4
Zhang, Y.5
Decker, M.6
-
258
-
-
70349481513
-
The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds
-
Hudson SA, Ecroyd H, Kee TW, Carver JA. The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds. FEBS J 276: 5960-72 (2009).
-
(2009)
FEBS J
, vol.276
, pp. 5960-72
-
-
Hudson, S.A.1
Ecroyd, H.2
Kee, T.W.3
Carver, J.A.4
|