메뉴 건너뛰기




Volumn 126, Issue 9 SPEC. ISS., 2005, Pages 987-1002

Toward a unified theory of caloric restriction and longevity regulation

Author keywords

Aging; HDAC; Histone deacetylase; NAMPT; Nicotinamide; PBEF; Resveratrol; SIR2; Sirtuin; Visfatin; Xenohormesis

Indexed keywords

BUFORMIN; BUTEIN; CORTICOSTERONE; DEOXYGLUCOSE; GLUCOCORTICOID; GROWTH HORMONE; METFORMIN; NICOTINAMIDE; PHENFORMIN; PICEATANNOL; QUERCETIN; REACTIVE OXYGEN METABOLITE; RESVERATROL; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN; THYROTROPIN;

EID: 22744450382     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2005.03.019     Document Type: Article
Times cited : (498)

References (215)
  • 1
    • 8844247034 scopus 로고    scopus 로고
    • Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes
    • R.R. Alcendor, L.A. Kirshenbaum, S. Imai, S.F. Vatner, and J. Sadoshima Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes Circ. Res. 95 2004 971 980
    • (2004) Circ. Res. , vol.95 , pp. 971-980
    • Alcendor, R.R.1    Kirshenbaum, L.A.2    Imai, S.3    Vatner, S.F.4    Sadoshima, J.5
  • 2
    • 0038329323 scopus 로고    scopus 로고
    • Nicotinamide and Pncl govern lifespan extension by calorie restriction in S. cerevisiae
    • R.M. Anderson, K.J. Bitterman, J.G. Wood, O. Medvedik, and D.A. Sinclair Nicotinamide and Pncl govern lifespan extension by calorie restriction in S. cerevisiae Nature 423 2003 181 185
    • (2003) Nature , vol.423 , pp. 181-185
    • Anderson, R.M.1    Bitterman, K.J.2    Wood, J.G.3    Medvedik, O.4    Sinclair, D.A.5
  • 3
    • 0037112081 scopus 로고    scopus 로고
    • Impact of aging and life-long calorie restriction on expression of apoptosis-related genes in male F344 rat liver
    • K. Ando, Y. Higami, T. Tsuchiya, T. Kanematsu, and I. Shimokawa Impact of aging and life-long calorie restriction on expression of apoptosis-related genes in male F344 rat liver Microsc. Res. Tech. 59 2002 293 300
    • (2002) Microsc. Res. Tech. , vol.59 , pp. 293-300
    • Ando, K.1    Higami, Y.2    Tsuchiya, T.3    Kanematsu, T.4    Shimokawa, I.5
  • 4
    • 0344394514 scopus 로고    scopus 로고
    • Insulin and longevity: Antidiabetic biguanides as geroprotectors
    • V.N. Anisimov, A.V. Semenchenko, and A.I. Yashin Insulin and longevity: antidiabetic biguanides as geroprotectors Biogerontology 4 2003 297 307
    • (2003) Biogerontology , vol.4 , pp. 297-307
    • Anisimov, V.N.1    Semenchenko, A.V.2    Yashin, A.I.3
  • 5
    • 1642395033 scopus 로고    scopus 로고
    • Tipping the balance toward longevity
    • A. Antebi Tipping the balance toward longevity Dev. Cell 6 2004 315 316
    • (2004) Dev. Cell , vol.6 , pp. 315-316
    • Antebi, A.1
  • 6
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • T. Araki, Y. Sasaki, and J. Milbrandt Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration Science 305 2004 1010 1013
    • (2004) Science , vol.305 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 7
    • 0026058667 scopus 로고
    • Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila
    • R. Arking, S. Buck, A. Berrios, S. Dwyer, and G.T. Baker 3rd Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain of Drosophila Dev. Genet. 12 1991 362 370
    • (1991) Dev. Genet. , vol.12 , pp. 362-370
    • Arking, R.1    Buck, S.2    Berrios, A.3    Dwyer, S.4    Baker III, G.T.5
  • 8
    • 14544284354 scopus 로고    scopus 로고
    • Does caloric restriction in the laboratory simply prevent overfeeding and return house mice to their natural level of food intake?
    • S.N. Austad Does caloric restriction in the laboratory simply prevent overfeeding and return house mice to their natural level of food intake? Sci. Aging Knowledge Environ. 6 2001 3
    • (2001) Sci. Aging Knowledge Environ. , vol.6 , pp. 3
    • Austad, S.N.1
  • 9
    • 2542446099 scopus 로고    scopus 로고
    • Aging in vertebrates, and the effect of caloric restriction: A mitochondrial free radical production-DNA damage mechanism?
    • G. Barja Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production-DNA damage mechanism? Biol. Rev. Camb. Philos. Soc. 79 2004 235 251
    • (2004) Biol. Rev. Camb. Philos. Soc. , vol.79 , pp. 235-251
    • Barja, G.1
  • 12
    • 0035098133 scopus 로고    scopus 로고
    • The role of fat depletion in the biological benefits of caloric restriction
    • N. Barzilai, and I. Gabriely The role of fat depletion in the biological benefits of caloric restriction J. Nutr. 131 2001 903S 906S
    • (2001) J. Nutr. , vol.131
    • Barzilai, N.1    Gabriely, I.2
  • 13
    • 0033039097 scopus 로고    scopus 로고
    • Revisiting the role of fat mass in the life extension induced by caloric restriction
    • N. Barzilai, and G. Gupta Revisiting the role of fat mass in the life extension induced by caloric restriction J. Gerontol. A Biol. Sci. Med. Sci. 54 1999 B89 B96 discussion B97-B98
    • (1999) J. Gerontol. a Biol. Sci. Med. Sci. , vol.54
    • Barzilai, N.1    Gupta, G.2
  • 14
    • 4444357274 scopus 로고    scopus 로고
    • An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster
    • J.H. Bauer, S. Goupil, G.B. Garber, and S.L. Helfand An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster Proc. Natl. Acad. Sci. U.S.A. 101 2004 12980 12985
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 12980-12985
    • Bauer, J.H.1    Goupil, S.2    Garber, G.B.3    Helfand, S.L.4
  • 16
    • 0000817678 scopus 로고
    • Nutrition and longevity in the rat. II. Longevity and onset of disease with different levels of food intake
    • B.N. Berg, and H.S. Simms Nutrition and longevity in the rat. II. Longevity and onset of disease with different levels of food intake J. Nutr. 71 1960 255 263
    • (1960) J. Nutr. , vol.71 , pp. 255-263
    • Berg, B.N.1    Simms, H.S.2
  • 17
    • 0019215950 scopus 로고
    • Changes in adipose mass and cellularity through the adult life of rats fed ad libitum or a life-prolonging restricted diet
    • H.A. Bertrand, F.T. Lynd, E.J. Masoro, and B.P. Yu Changes in adipose mass and cellularity through the adult life of rats fed ad libitum or a life-prolonging restricted diet J. Gerontol. 35 1980 827 835
    • (1980) J. Gerontol. , vol.35 , pp. 827-835
    • Bertrand, H.A.1    Lynd, F.T.2    Masoro, E.J.3    Yu, B.P.4
  • 18
    • 0036297527 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol
    • K.P. Bhat, and J.M. Pezzuto Cancer chemopreventive activity of resveratrol Ann. N. Y. Acad. Sci. 957 2002 210 229
    • (2002) Ann. N. Y. Acad. Sci. , vol.957 , pp. 210-229
    • Bhat, K.P.1    Pezzuto, J.M.2
  • 19
    • 0037160097 scopus 로고    scopus 로고
    • Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
    • K.J. Bitterman, R.M. Anderson, H.Y. Cohen, M. Latorre-Esteves, and D.A. Sinclair Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1 J. Biol. Chem. 277 2002 45099 45107
    • (2002) J. Biol. Chem. , vol.277 , pp. 45099-45107
    • Bitterman, K.J.1    Anderson, R.M.2    Cohen, H.Y.3    Latorre-Esteves, M.4    Sinclair, D.A.5
  • 20
    • 0141677687 scopus 로고    scopus 로고
    • Longevity regulation in Saccharomyces cerevisiae: Linking metabolism, genome stability, and heterochromatin
    • K.J. Bitterman, O. Medvedik, and D.A. Sinclair Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin Microbiol. Mol. Biol. Rev. 67 2003 376 399 (table of contents)
    • (2003) Microbiol. Mol. Biol. Rev. , vol.67 , pp. 376-399
    • Bitterman, K.J.1    Medvedik, O.2    Sinclair, D.A.3
  • 21
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • M. Bluher, B.B. Kahn, and C.R. Kahn Extended longevity in mice lacking the insulin receptor in adipose tissue Science 299 2003 572 574
    • (2003) Science , vol.299 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 22
    • 0035978884 scopus 로고    scopus 로고
    • Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans
    • B.P. Braeckman, K. Houthoofd, and J.R. Vanfleteren Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans Mech. Ageing Dev. 122 2001 673 693
    • (2001) Mech. Ageing Dev. , vol.122 , pp. 673-693
    • Braeckman, B.P.1    Houthoofd, K.2    Vanfleteren, J.R.3
  • 23
    • 0035978884 scopus 로고    scopus 로고
    • Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans
    • B.P. Braeckman, K. Houthoofd, and J.R. Vanfleteren Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans Mech. Ageing Dev. 122 2001 673 693
    • (2001) Mech. Ageing Dev. , vol.122 , pp. 673-693
    • Braeckman, B.P.1    Houthoofd, K.2    Vanfleteren, J.R.3
  • 24
    • 0038817360 scopus 로고    scopus 로고
    • Assessing metabolic activity in aging Caenorhabditis elegans: Concepts and controversies
    • B.P. Braeckman, K. Houthoofd, and J.R. Vanfleteren Assessing metabolic activity in aging Caenorhabditis elegans: concepts and controversies Aging Cell 1 2002 82 88 discussion 102-103
    • (2002) Aging Cell , vol.1 , pp. 82-88
    • Braeckman, B.P.1    Houthoofd, K.2    Vanfleteren, J.R.3
  • 26
    • 0035218414 scopus 로고    scopus 로고
    • Hormesis and debilitation effects in stress experiments using the nematode worm Caenorhabditis elegans: The model of balance between cell damage and HSP levels
    • A. Butov, T. Johnson, J. Cypser, I. Sannikov, M. Volkov, M. Sehl, and A. Yashin Hormesis and debilitation effects in stress experiments using the nematode worm Caenorhabditis elegans: the model of balance between cell damage and HSP levels Exp. Gerontol. 37 2001 57 66
    • (2001) Exp. Gerontol. , vol.37 , pp. 57-66
    • Butov, A.1    Johnson, T.2    Cypser, J.3    Sannikov, I.4    Volkov, M.5    Sehl, M.6    Yashin, A.7
  • 27
    • 2442562406 scopus 로고    scopus 로고
    • Hormesis: From marginalization to mainstream: A case for hormesis as the default dose-response model in risk assessment
    • E.J. Calabrese Hormesis: from marginalization to mainstream: a case for hormesis as the default dose-response model in risk assessment Toxicol. Appl. Pharmacol. 197 2004 125 136
    • (2004) Toxicol. Appl. Pharmacol. , vol.197 , pp. 125-136
    • Calabrese, E.J.1
  • 28
    • 0023223310 scopus 로고
    • The occurrence of chemically induced hormesis
    • E.J. Calabrese, M.E. McCarthy, and E. Kenyon The occurrence of chemically induced hormesis Health Phys. 52 1987 531 541
    • (1987) Health Phys. , vol.52 , pp. 531-541
    • Calabrese, E.J.1    McCarthy, M.E.2    Kenyon, E.3
  • 29
    • 0034575582 scopus 로고    scopus 로고
    • Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism.
    • N.Y. Calingasan, and G.E. Gibson Dietary restriction attenuates the neuronal loss, induction of heme oxygenase-1 and blood-brain barrier breakdown induced by impaired oxidative metabolism. Brain Res. 885 2000 62 69
    • (2000) Brain Res. , vol.885 , pp. 62-69
    • Calingasan, N.Y.1    Gibson, G.E.2
  • 30
    • 0035845492 scopus 로고    scopus 로고
    • Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice
    • S.X. Cao, J.M. Dhahbi, P.L. Mote, and S.R. Spindler Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice Proc. Natl. Acad. Sci. U.S.A. 98 2001 10630 10635
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 10630-10635
    • Cao, S.X.1    Dhahbi, J.M.2    Mote, P.L.3    Spindler, S.R.4
  • 31
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - A unifying system for energy control
    • D. Carling The AMP-activated protein kinase cascade - a unifying system for energy control Trends Biochem. Sci. 29 2004 18 24
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 18-24
    • Carling, D.1
  • 32
    • 0028155756 scopus 로고
    • Adaptation of muscle glucose transport with caloric restriction in adult, middle-aged, and old rats
    • G.D. Cartee, E.W. Kietzke, and C. Briggs-Tung Adaptation of muscle glucose transport with caloric restriction in adult, middle-aged, and old rats Am. J. Physiol. 266 1994 R1443 R1447
    • (1994) Am. J. Physiol. , vol.266
    • Cartee, G.D.1    Kietzke, E.W.2    Briggs-Tung, C.3
  • 33
    • 3242714939 scopus 로고    scopus 로고
    • Measurement of the 4,834-bp mitochondrial DNA deletion level in aging rat liver and brain subjected or not to caloric restriction diet
    • P. Cassano, A.M. Lezza, C. Leeuwenburgh, P. Cantatore, and M.N. Gadaleta Measurement of the 4,834-bp mitochondrial DNA deletion level in aging rat liver and brain subjected or not to caloric restriction diet Ann. N. Y. Acad. Sci. 1019 2004 269 273
    • (2004) Ann. N. Y. Acad. Sci. , vol.1019 , pp. 269-273
    • Cassano, P.1    Lezza, A.M.2    Leeuwenburgh, C.3    Cantatore, P.4    Gadaleta, M.N.5
  • 34
    • 0033756222 scopus 로고    scopus 로고
    • Fisher, Medawar, Hamilton and the evolution of aging
    • B. Charlesworth Fisher, Medawar, Hamilton and the evolution of aging Genetics 156 2000 927 931
    • (2000) Genetics , vol.156 , pp. 927-931
    • Charlesworth, B.1
  • 39
    • 0343943912 scopus 로고
    • Longevity is determined by specific genes: Testing the hypothesis
    • R.C. Adelman G.S. Roth CRC Press, Inc. Boca Raton, FL
    • R.G. Cutler Longevity is determined by specific genes: testing the hypothesis R.C. Adelman G.S. Roth Testing the Theories of Aging 1982 CRC Press, Inc. Boca Raton, FL 24 114
    • (1982) Testing the Theories of Aging , pp. 24-114
    • Cutler, R.G.1
  • 40
    • 0036198149 scopus 로고    scopus 로고
    • Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity
    • J.R. Cypser, and T.E. Johnson Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity J. Gerontol. A Biol. Sci. Med. Sci. 57 2002 B109 B114
    • (2002) J. Gerontol. a Biol. Sci. Med. Sci. , vol.57
    • Cypser, J.R.1    Johnson, T.E.2
  • 41
    • 0042386510 scopus 로고    scopus 로고
    • Hormesis in Caenorhabditis elegans dauer-defective mutants
    • J.R. Cypser, and T.E. Johnson Hormesis in Caenorhabditis elegans dauer-defective mutants Biogerontology 4 2003 203 214
    • (2003) Biogerontology , vol.4 , pp. 203-214
    • Cypser, J.R.1    Johnson, T.E.2
  • 43
    • 0029559321 scopus 로고
    • Paraquat resistance and starvation conditions in the selection of longevity extremes in Drosophila melanogaster populations previously selected for long and short developmental period
    • G.L. da Cunha, I.B. da Cruz, P. Fiorino, and A.K. de Oliveira Paraquat resistance and starvation conditions in the selection of longevity extremes in Drosophila melanogaster populations previously selected for long and short developmental period Dev. Genet. 17 1995 352 361
    • (1995) Dev. Genet. , vol.17 , pp. 352-361
    • Da Cunha, G.L.1    Da Cruz, I.B.2    Fiorino, P.3    De Oliveira, A.K.4
  • 45
    • 0032415426 scopus 로고    scopus 로고
    • Calorie restriction increases cell surface GLUT-4 in insulin-stimulated skeletal muscle
    • D.J. Dean, J.T. Brozinick Jr., S.W. Cushman, and G.D. Cartee Calorie restriction increases cell surface GLUT-4 in insulin-stimulated skeletal muscle Am. J. Physiol. 275 1998 E957 E964
    • (1998) Am. J. Physiol. , vol.275
    • Dean, D.J.1    Brozinick Jr., J.T.2    Cushman, S.W.3    Cartee, G.D.4
  • 46
    • 0031765026 scopus 로고    scopus 로고
    • Comparison of the effects of 20 days and 15 months of calorie restriction on male Fischer 344 rats
    • D.J. Dean, A.C. Gazdag, T.J. Wetter, and G.D. Cartee Comparison of the effects of 20 days and 15 months of calorie restriction on male Fischer 344 rats Aging (Milano) 10 1998 303 307
    • (1998) Aging (Milano) , vol.10 , pp. 303-307
    • Dean, D.J.1    Gazdag, A.C.2    Wetter, T.J.3    Cartee, G.D.4
  • 47
    • 1842609938 scopus 로고    scopus 로고
    • Re-adaptation hypothesis: Explaining health benefits of caloric restriction
    • H. Dehmelt Re-adaptation hypothesis: explaining health benefits of caloric restriction Med. Hypotheses 62 2004 620 624
    • (2004) Med. Hypotheses , vol.62 , pp. 620-624
    • Dehmelt, H.1
  • 50
    • 0018895934 scopus 로고
    • Effect of treatment with phenformin, diphenylhydantoin or l-dopa on life span and tumour incidence in C3H/Sn mice
    • V.M. Dilman, and V.N. Anisimov Effect of treatment with phenformin, diphenylhydantoin or l-dopa on life span and tumour incidence in C3H/Sn mice Gerontology 26 1980 241 246
    • (1980) Gerontology , vol.26 , pp. 241-246
    • Dilman, V.M.1    Anisimov, V.N.2
  • 52
    • 0345547465 scopus 로고    scopus 로고
    • Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice
    • J.J. Docherty, J.S. Smith, M.M. Fu, T. Stoner, and T. Booth Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice Antivir. Res. 61 2004 19 26
    • (2004) Antivir. Res. , vol.61 , pp. 19-26
    • Docherty, J.J.1    Smith, J.S.2    Fu, M.M.3    Stoner, T.4    Booth, T.5
  • 53
    • 0842270038 scopus 로고    scopus 로고
    • Oxidative stress and aging
    • W. Droge Oxidative stress and aging Adv. Exp. Med. Biol. 543 2003 191 200
    • (2003) Adv. Exp. Med. Biol. , vol.543 , pp. 191-200
    • Droge, W.1
  • 54
    • 0034798972 scopus 로고    scopus 로고
    • The effects of different levels of dietary restriction on aging and survival in the Sprague-Dawley rat: Implications for chronic studies
    • P.H. Duffy, J.E. Seng, S.M. Lewis, M.A. Mayhugh, A. Aidoo, D.G. Hattan, D.A. Casciano, and R.J. Feuers The effects of different levels of dietary restriction on aging and survival in the Sprague-Dawley rat: implications for chronic studies Aging (Milano) 13 2001 263 272
    • (2001) Aging (Milano) , vol.13 , pp. 263-272
    • Duffy, P.H.1    Seng, J.E.2    Lewis, S.M.3    Mayhugh, M.A.4    Aidoo, A.5    Hattan, D.G.6    Casciano, D.A.7    Feuers, R.J.8
  • 55
    • 3543028676 scopus 로고    scopus 로고
    • Understanding aging: Revealing order out of chaos
    • E. Dufour, and N.G. Larsson Understanding aging: revealing order out of chaos Biochim. Biophys. Acta 1658 2004 122 132
    • (2004) Biochim. Biophys. Acta , vol.1658 , pp. 122-132
    • Dufour, E.1    Larsson, N.G.2
  • 56
    • 0142149194 scopus 로고    scopus 로고
    • Plasmid accumulation reduces life span in Saccharomyces cerevisiae
    • A.A. Falcon, and J.P. Aris Plasmid accumulation reduces life span in Saccharomyces cerevisiae J. Biol. Chem. 278 2003 41607 41617
    • (2003) J. Biol. Chem. , vol.278 , pp. 41607-41617
    • Falcon, A.A.1    Aris, J.P.2
  • 58
    • 0023831256 scopus 로고
    • A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility
    • D.B. Friedman, and T.E. Johnson A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility Genetics 118 1988 75 86
    • (1988) Genetics , vol.118 , pp. 75-86
    • Friedman, D.B.1    Johnson, T.E.2
  • 59
    • 0033600176 scopus 로고    scopus 로고
    • Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
    • R.A. Frye Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity Biochem. Biophys. Res. Commun. 260 1999 273 279
    • (1999) Biochem. Biophys. Res. Commun. , vol.260 , pp. 273-279
    • Frye, R.A.1
  • 60
    • 0033887456 scopus 로고    scopus 로고
    • Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
    • R.A. Frye Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins Biochem. Biophys. Res. Commun. 273 2000 793 798
    • (2000) Biochem. Biophys. Res. Commun. , vol.273 , pp. 793-798
    • Frye, R.A.1
  • 62
    • 0035882757 scopus 로고    scopus 로고
    • Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes
    • J.P. Fulgencio, C. Kohl, J. Girard, and J.P. Pegorier Effect of metformin on fatty acid and glucose metabolism in freshly isolated hepatocytes and on specific gene expression in cultured hepatocytes Biochem. Pharmacol. 62 2001 439 446
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 439-446
    • Fulgencio, J.P.1    Kohl, C.2    Girard, J.3    Pegorier, J.P.4
  • 63
    • 1642580758 scopus 로고    scopus 로고
    • Nicotinamide clearance by Pncl directly regulates Sir2-mediated silencing and longevity
    • C.M. Gallo, D.L. Smith Jr., and J.S. Smith Nicotinamide clearance by Pncl directly regulates Sir2-mediated silencing and longevity Mol. Cell Biol. 24 2004 1301 1312
    • (2004) Mol. Cell Biol. , vol.24 , pp. 1301-1312
    • Gallo, C.M.1    Smith Jr., D.L.2    Smith, J.S.3
  • 64
    • 4143050290 scopus 로고    scopus 로고
    • The interaction between FOXO and SIRT1: Tipping the balance towards survival
    • M.E. Giannakou, and L. Partridge The interaction between FOXO and SIRT1: tipping the balance towards survival Trends Cell Biol. 14 2004 408 412
    • (2004) Trends Cell Biol. , vol.14 , pp. 408-412
    • Giannakou, M.E.1    Partridge, L.2
  • 66
    • 0024536650 scopus 로고
    • A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA
    • S. Gottlieb, and R.E. Esposito A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA Cell 56 1989 771 776
    • (1989) Cell , vol.56 , pp. 771-776
    • Gottlieb, S.1    Esposito, R.E.2
  • 67
    • 0035914304 scopus 로고    scopus 로고
    • Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening
    • C.C.E. Grozinger, H.E. Blackwell, D. Moazed, and S.L. Schreiber Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening J. Biol. Chem. 276 2001 38837 38843
    • (2001) J. Biol. Chem. , vol.276 , pp. 38837-38843
    • Grozinger, C.C.E.1    Blackwell, H.E.2    Moazed, D.3    Schreiber, S.L.4
  • 68
    • 0034853619 scopus 로고    scopus 로고
    • Effects of age and food restriction on oxidative DNA damage and antioxidant enzyme activities in the mouse aorta
    • Z.M. Guo, H. Yang, M.L. Hamilton, H. VanRemmen, and A. Richardson Effects of age and food restriction on oxidative DNA damage and antioxidant enzyme activities in the mouse aorta Mech. Ageing Dev. 122 2001 1771 1786
    • (2001) Mech. Ageing Dev. , vol.122 , pp. 1771-1786
    • Guo, Z.M.1    Yang, H.2    Hamilton, M.L.3    Vanremmen, H.4    Richardson, A.5
  • 70
    • 0001001689 scopus 로고
    • Effects of food restriction on aging: Separation of food intake and adiposity
    • D.E. Harrison, J.R. Archer, and C.M. Astle Effects of food restriction on aging: separation of food intake and adiposity Proc. Natl. Acad. Sci. U.S.A. 81 1984 1835 1838
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 1835-1838
    • Harrison, D.E.1    Archer, J.R.2    Astle, C.M.3
  • 71
    • 0033457962 scopus 로고    scopus 로고
    • Stress resistance and longevity in selected lines of Drosophila melanogaster
    • L.G. Harshman, K.M. Moore, M.A. Sty, and M.M. Magwire Stress resistance and longevity in selected lines of Drosophila melanogaster Neurobiol. Aging 20 1999 521 529
    • (1999) Neurobiol. Aging , vol.20 , pp. 521-529
    • Harshman, L.G.1    Moore, K.M.2    Sty, M.A.3    Magwire, M.M.4
  • 74
    • 0037470539 scopus 로고    scopus 로고
    • Genetics and the specificity of the aging process
    • S. Hekimi, and L. Guarente Genetics and the specificity of the aging process Science 299 2003 1351 1354
    • (2003) Science , vol.299 , pp. 1351-1354
    • Hekimi, S.1    Guarente, L.2
  • 75
    • 0038826959 scopus 로고    scopus 로고
    • Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress
    • M.J. Hercus, V. Loeschcke, and S.I. Rattan Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress Biogerontology 4 2003 149 156
    • (2003) Biogerontology , vol.4 , pp. 149-156
    • Hercus, M.J.1    Loeschcke, V.2    Rattan, S.I.3
  • 76
    • 0027154719 scopus 로고
    • Expression of heat shock protein 70 is altered by age and diet at the level of transcription
    • A.R. Heydari, B. Wu, R. Takahashi, R. Strong, and A. Richardson Expression of heat shock protein 70 is altered by age and diet at the level of transcription Mol. Cell Biol. 13 1993 2909 2918
    • (1993) Mol. Cell Biol. , vol.13 , pp. 2909-2918
    • Heydari, A.R.1    Wu, B.2    Takahashi, R.3    Strong, R.4    Richardson, A.5
  • 77
    • 3242659914 scopus 로고    scopus 로고
    • Effects of age and caloric restriction on brain neuronal cell death/survival
    • A. Hiona, and C. Leeuwenburgh Effects of age and caloric restriction on brain neuronal cell death/survival Ann. N. Y. Acad. Sci. 1019 2004 96 105
    • (2004) Ann. N. Y. Acad. Sci. , vol.1019 , pp. 96-105
    • Hiona, A.1    Leeuwenburgh, C.2
  • 78
    • 0024655426 scopus 로고
    • Food, reproduction and longevity: Is the extended lifespan of calorie-restricted animals an evolutionary adaptation?
    • R. Holliday Food, reproduction and longevity: is the extended lifespan of calorie-restricted animals an evolutionary adaptation? Bioessays 10 1989 125 127
    • (1989) Bioessays , vol.10 , pp. 125-127
    • Holliday, R.1
  • 79
    • 0042886011 scopus 로고    scopus 로고
    • Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans
    • K. Houthoofd, B.P. Braeckman, T.E. Johnson, and J.R. Vanfleteren Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans Exp. Gerontol. 38 2003 947 954
    • (2003) Exp. Gerontol. , vol.38 , pp. 947-954
    • Houthoofd, K.1    Braeckman, B.P.2    Johnson, T.E.3    Vanfleteren, J.R.4
  • 80
    • 0036975161 scopus 로고    scopus 로고
    • Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans
    • K. Houthoofd, B.P. Braeckman, I. Lenaerts, K. Brys, A. De Vreese, S. Van Eygen, and J.R. Vanfleteren Axenic growth up-regulates mass-specific metabolic rate, stress resistance, and extends life span in Caenorhabditis elegans Exp. Gerontol. 37 2002 1371 1378
    • (2002) Exp. Gerontol. , vol.37 , pp. 1371-1378
    • Houthoofd, K.1    Braeckman, B.P.2    Lenaerts, I.3    Brys, K.4    De Vreese, A.5    Van Eygen, S.6    Vanfleteren, J.R.7
  • 82
    • 84882541900 scopus 로고    scopus 로고
    • Dietary restriction, hormesis, and small molecule mimetics
    • E.J. Masoro S.N. Austad 6th edn. Academic Press London
    • K.T. Howitz, and D.A. Sinclair Dietary restriction, hormesis, and small molecule mimetics E.J. Masoro S.N. Austad Handbook of the Biology of Aging 6th edn. 2005 Academic Press London
    • (2005) Handbook of the Biology of Aging
    • Howitz, K.T.1    Sinclair, D.A.2
  • 83
    • 12344327355 scopus 로고    scopus 로고
    • Visfatin: A new adipokine
    • C. Hug, and H.F. Lodish Visfatin: a new adipokine Science 307 5708 2004 366 367
    • (2004) Science , vol.307 , Issue.5708 , pp. 366-367
    • Hug, C.1    Lodish, H.F.2
  • 84
    • 3543062946 scopus 로고    scopus 로고
    • Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster
    • A.J. Hulbert, D.J. Clancy, W. Mair, B.P. Braeckman, D. Gems, and L. Partridge Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster Exp. Gerontol. 39 2004 1137 1143
    • (2004) Exp. Gerontol. , vol.39 , pp. 1137-1143
    • Hulbert, A.J.1    Clancy, D.J.2    Mair, W.3    Braeckman, B.P.4    Gems, D.5    Partridge, L.6
  • 87
    • 0033556060 scopus 로고    scopus 로고
    • Geroprotector effectiveness of melatonin: Investigation of lifespan of Drosophila melanogaster
    • D.M. Izmaylov, and L.K. Obukhova Geroprotector effectiveness of melatonin: investigation of lifespan of Drosophila melanogaster Mech. Ageing Dev. 106 1999 233 240
    • (1999) Mech. Ageing Dev. , vol.106 , pp. 233-240
    • Izmaylov, D.M.1    Obukhova, L.K.2
  • 88
    • 0031967803 scopus 로고    scopus 로고
    • Upregulation of apoptosis with dietary restriction: Implications for carcinogenesis and aging
    • S.J. James, L. Muskhelishvili, D.W. Gaylor, A. Turturro, and R. Hart Upregulation of apoptosis with dietary restriction: implications for carcinogenesis and aging Environ. Health Perspect. 106 Suppl. 1 1998 307 312
    • (1998) Environ. Health Perspect. , vol.106 , Issue.1 SUPPL. , pp. 307-312
    • James, S.J.1    Muskhelishvili, L.2    Gaylor, D.W.3    Turturro, A.4    Hart, R.5
  • 90
    • 85047693796 scopus 로고    scopus 로고
    • Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis
    • S.H. Jia, Y. Li, J. Parodo, A. Kapus, L. Fan, O.D. Rotstein, and J.C. Marshall Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis J. Clin. Invest. 113 2004 1318 1327
    • (2004) J. Clin. Invest. , vol.113 , pp. 1318-1327
    • Jia, S.H.1    Li, Y.2    Parodo, J.3    Kapus, A.4    Fan, L.5    Rotstein, O.D.6    Marshall, J.C.7
  • 91
    • 0033738362 scopus 로고    scopus 로고
    • An intervention resembling caloric restriction prolongs life span and retards aging in yeast
    • J.C. Jiang, E. Jaruga, M.V. Repnevskaya, and S.M. Jazwinski An intervention resembling caloric restriction prolongs life span and retards aging in yeast FASEB J. 14 2000 2135 2137
    • (2000) FASEB J. , vol.14 , pp. 2135-2137
    • Jiang, J.C.1    Jaruga, E.2    Repnevskaya, M.V.3    Jazwinski, S.M.4
  • 92
    • 0023780523 scopus 로고
    • Radiation effects on life span in Caenorhabditis elegans
    • T.E. Johnson, and P.S. Hartman Radiation effects on life span in Caenorhabditis elegans J. Gerontol. 43 1988 B137 B141
    • (1988) J. Gerontol. , vol.43
    • Johnson, T.E.1    Hartman, P.S.2
  • 93
    • 19344374925 scopus 로고    scopus 로고
    • Sir2-independent life span extension by calorie restriction in yeast
    • M. Kaeberlein, K.T. Kirkland, S. Fields, and B.K. Kennedy Sir2-independent life span extension by calorie restriction in yeast PLoS Biol. 2 2004 E296
    • (2004) PLoS Biol. , vol.2 , pp. 296
    • Kaeberlein, M.1    Kirkland, K.T.2    Fields, S.3    Kennedy, B.K.4
  • 94
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • M. Kaeberlein, M. McVey, and L. Guarente The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms Genes Dev. 13 1999 2570 2580
    • (1999) Genes Dev. , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 95
    • 0024242627 scopus 로고
    • Effect of diet restriction on glucose metabolism and insulin responsiveness in aging rats
    • N. Kalant, J. Stewart, and R. Kaplan Effect of diet restriction on glucose metabolism and insulin responsiveness in aging rats Mech. Ageing Dev. 46 1988 89 104
    • (1988) Mech. Ageing Dev. , vol.46 , pp. 89-104
    • Kalant, N.1    Stewart, J.2    Kaplan, R.3
  • 96
    • 0028897013 scopus 로고
    • Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae
    • B.K. Kennedy, N.R. Austriaco Jr., J. Zhang, and L. Guarente Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae Cell 80 1995 485 496
    • (1995) Cell , vol.80 , pp. 485-496
    • Kennedy, B.K.1    Austriaco Jr., N.R.2    Zhang, J.3    Guarente, L.4
  • 98
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • C. Kenyon, J. Chang, E. Gensch, A. Rudner, and R. Tabtiang A C. elegans mutant that lives twice as long as wild type Nature 366 1993 461 464
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 101
    • 3042670289 scopus 로고    scopus 로고
    • Resveratrol, a red wine polyphenol, protects spinal cord from ischemia-reperfusion injury
    • U. Kiziltepe, N.N. Turan, U. Han, A.T. Ulus, and F. Akar Resveratrol, a red wine polyphenol, protects spinal cord from ischemia-reperfusion injury J. Vasc. Surg. 40 2004 138 145
    • (2004) J. Vasc. Surg. , vol.40 , pp. 138-145
    • Kiziltepe, U.1    Turan, N.N.2    Han, U.3    Ulus, A.T.4    Akar, F.5
  • 103
    • 0037312020 scopus 로고    scopus 로고
    • How does calorie restriction work?
    • J. Koubova, and L. Guarente How does calorie restriction work? Genes Dev. 17 2003 313 321
    • (2003) Genes Dev. , vol.17 , pp. 313-321
    • Koubova, J.1    Guarente, L.2
  • 105
    • 2342653588 scopus 로고    scopus 로고
    • Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts
    • O. Kutuk, M. Adli, G. Poli, and H. Basaga Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts Biofactors 20 2004 1 10
    • (2004) Biofactors , vol.20 , pp. 1-10
    • Kutuk, O.1    Adli, M.2    Poli, G.3    Basaga, H.4
  • 106
    • 4344590155 scopus 로고    scopus 로고
    • Small molecules that regulate lifespan: Evidence for xenohormesis
    • D.W. Lamming, J.G. Wood, and D.A. Sinclair Small molecules that regulate lifespan: evidence for xenohormesis Mol. Microbiol. 53 2004 1003 1009
    • (2004) Mol. Microbiol. , vol.53 , pp. 1003-1009
    • Lamming, D.W.1    Wood, J.G.2    Sinclair, D.A.3
  • 108
    • 0037466652 scopus 로고    scopus 로고
    • DAF-16 target genes that control C. elegans life-span and metabolism
    • S.S. Lee, S. Kennedy, A.C. Tolonen, and G. Ruvkun DAF-16 target genes that control C. elegans life-span and metabolism Science 300 2003 644 647
    • (2003) Science , vol.300 , pp. 644-647
    • Lee, S.S.1    Kennedy, S.2    Tolonen, A.C.3    Ruvkun, G.4
  • 109
    • 0022375067 scopus 로고
    • The effects of aging and chronic dietary restriction on whole body growth and protein turnover in the rat
    • S.E. Lewis, D.F. Goldspink, J.G. Phillips, B.J. Merry, and A.M. Holehan The effects of aging and chronic dietary restriction on whole body growth and protein turnover in the rat Exp. Gerontol. 20 1985 253 263
    • (1985) Exp. Gerontol. , vol.20 , pp. 253-263
    • Lewis, S.E.1    Goldspink, D.F.2    Phillips, J.G.3    Merry, B.J.4    Holehan, A.M.5
  • 110
    • 0035006715 scopus 로고    scopus 로고
    • Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues
    • S.S. Lim, S.H. Jung, J. Ji, K.H. Shin, and S.R. Keum Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues J. Pharm. Pharmacol. 53 2001 653 668
    • (2001) J. Pharm. Pharmacol. , vol.53 , pp. 653-668
    • Lim, S.S.1    Jung, S.H.2    Ji, J.3    Shin, K.H.4    Keum, S.R.5
  • 111
    • 0034703217 scopus 로고    scopus 로고
    • Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
    • S.J. Lin, P.A. Defossez, and L. Guarente Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae Science 289 2000 2126 2128
    • (2000) Science , vol.289 , pp. 2126-2128
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 113
    • 0033291371 scopus 로고    scopus 로고
    • Diet and ageing: The possible relation to reactive oxygen species
    • D.G. Lindsay Diet and ageing: the possible relation to reactive oxygen species J. Nutr. Health Aging 3 1999 84 91
    • (1999) J. Nutr. Health Aging , vol.3 , pp. 84-91
    • Lindsay, D.G.1
  • 114
    • 0027763260 scopus 로고
    • Hypergravity and aging in Drosophila melanogaster: 7. New longevity data
    • F.A. Lints, P. Bullens, and E. Le Bourg Hypergravity and aging in Drosophila melanogaster: 7. New longevity data Exp. Gerontol. 28 1993 611 615
    • (1993) Exp. Gerontol. , vol.28 , pp. 611-615
    • Lints, F.A.1    Bullens, P.2    Le Bourg, E.3
  • 115
    • 0034910445 scopus 로고    scopus 로고
    • Hormesis - A new hope for ageing studies or a poor second to genetics?
    • G.J. Lithgow Hormesis - a new hope for ageing studies or a poor second to genetics? Hum. Exp. Toxicol. 20 2001 301 303 discussion 319-320
    • (2001) Hum. Exp. Toxicol. , vol.20 , pp. 301-303
    • Lithgow, G.J.1
  • 117
    • 0028070138 scopus 로고
    • Dietary restriction attenuates age-related increases in rat skeletal muscle antioxidant enzyme activities
    • T.A. Luhtala, E.B. Roecker, T. Pugh, R.J. Feuers, and R. Weindruch Dietary restriction attenuates age-related increases in rat skeletal muscle antioxidant enzyme activities J. Gerontol. 49 1994 B231 B238
    • (1994) J. Gerontol. , vol.49
    • Luhtala, T.A.1    Roecker, E.B.2    Pugh, T.3    Feuers, R.J.4    Weindruch, R.5
  • 118
    • 0027101936 scopus 로고
    • Potential role of the modulation of fuel use in the antiaging action of dietary restriction
    • E.J. Masoro Potential role of the modulation of fuel use in the antiaging action of dietary restriction Ann. N. Y. Acad. Sci. 663 1992 403 411
    • (1992) Ann. N. Y. Acad. Sci. , vol.663 , pp. 403-411
    • Masoro, E.J.1
  • 119
    • 0029365086 scopus 로고
    • Antiaging action of caloric restriction: Endocrine and metabolic aspects
    • E.J. Masoro Antiaging action of caloric restriction: endocrine and metabolic aspects Obes. Res. 3 Suppl. 2 1995 241s 247s
    • (1995) Obes. Res. , vol.3 , Issue.2 SUPPL.
    • Masoro, E.J.1
  • 120
    • 0030451815 scopus 로고    scopus 로고
    • Possible mechanisms underlying the antiaging actions of caloric restriction
    • E.J. Masoro Possible mechanisms underlying the antiaging actions of caloric restriction Toxicol. Pathol. 24 1996 738 741
    • (1996) Toxicol. Pathol. , vol.24 , pp. 738-741
    • Masoro, E.J.1
  • 121
    • 0032111884 scopus 로고    scopus 로고
    • Influence of caloric intake on aging and on the response to stressors
    • E.J. Masoro Influence of caloric intake on aging and on the response to stressors J. Toxicol. Environ. Health B Crit. Rev. 1 1998 243 257
    • (1998) J. Toxicol. Environ. Health B Crit. Rev. , vol.1 , pp. 243-257
    • Masoro, E.J.1
  • 122
    • 0034033586 scopus 로고    scopus 로고
    • Caloric restriction and aging: An update
    • E.J. Masoro Caloric restriction and aging: an update Exp. Gerontol. 35 2000 299 305
    • (2000) Exp. Gerontol. , vol.35 , pp. 299-305
    • Masoro, E.J.1
  • 123
    • 0029848121 scopus 로고    scopus 로고
    • The evolution of the antiaging action of dietary restriction: A hypothesis
    • E.J. Masoro, and S.N. Austad The evolution of the antiaging action of dietary restriction: a hypothesis J. Gerontol. A Biol. Sci. Med. Sci. 51 1996 B387 B391
    • (1996) J. Gerontol. a Biol. Sci. Med. Sci. , vol.51
    • Masoro, E.J.1    Austad, S.N.2
  • 126
    • 0036304650 scopus 로고    scopus 로고
    • Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior
    • M.P. Mattson, S.L. Chan, and W. Duan Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior Physiol. Rev. 82 2002 637 672
    • (2002) Physiol. Rev. , vol.82 , pp. 637-672
    • Mattson, M.P.1    Chan, S.L.2    Duan, W.3
  • 127
    • 0036752830 scopus 로고    scopus 로고
    • Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: Modification by genes, diet and behavior
    • M.P. Mattson, W. Duan, S.L. Chan, A. Cheng, N. Haughey, D.S. Gary, Z. Guo, J. Lee, and K. Furukawa Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior Neurobiol. Aging 23 2002 695 705
    • (2002) Neurobiol. Aging , vol.23 , pp. 695-705
    • Mattson, M.P.1    Duan, W.2    Chan, S.L.3    Cheng, A.4    Haughey, N.5    Gary, D.S.6    Guo, Z.7    Lee, J.8    Furukawa, K.9
  • 128
    • 0022048716 scopus 로고
    • Does food restriction retard aging by reducing the metabolic rate?
    • R. McCarter, E.J. Masoro, and B.P. Yu Does food restriction retard aging by reducing the metabolic rate? Am. J. Physiol. 248 1985 E488 E490
    • (1985) Am. J. Physiol. , vol.248
    • McCarter, R.1    Masoro, E.J.2    Yu, B.P.3
  • 129
    • 3242777031 scopus 로고    scopus 로고
    • Chronic activation of AMP-activated kinase as a strategy for slowing aging
    • M.F. McCarty Chronic activation of AMP-activated kinase as a strategy for slowing aging Med. Hypotheses 63 2004 334 339
    • (2004) Med. Hypotheses , vol.63 , pp. 334-339
    • McCarty, M.F.1
  • 130
    • 0003062933 scopus 로고
    • Cellulose in the diet of mice and rats
    • C.M. McCay Cellulose in the diet of mice and rats J. Nutr. 1935 435 447
    • (1935) J. Nutr. , pp. 435-447
    • McCay, C.M.1
  • 131
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of lifespan and upon the ultimate body size
    • C.M. McCay, M.F. Crowell, and L.A. Maynard The effect of retarded growth upon the length of lifespan and upon the ultimate body size J. Nutr. 10 1935 63 79
    • (1935) J. Nutr. , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 132
    • 0016787079 scopus 로고
    • Retarded growth, life span, ultimate body size and age changes in the albino rat after feeding diets restricted in calories
    • C.M. McCay, L.A. Maynard, G. Sperling, and L.L. Barnes Retarded growth, life span, ultimate body size and age changes in the albino rat after feeding diets restricted in calories Nutr. Rev. 33 1975 241 243
    • (1975) Nutr. Rev. , vol.33 , pp. 241-243
    • McCay, C.M.1    Maynard, L.A.2    Sperling, G.3    Barnes, L.L.4
  • 133
    • 0002134284 scopus 로고
    • Old age and natural death
    • P.B. Medawar Old age and natural death Mod. Q. 1 1946 30 56
    • (1946) Mod. Q. , vol.1 , pp. 30-56
    • Medawar, P.B.1
  • 134
    • 0036828603 scopus 로고    scopus 로고
    • Molecular mechanisms linking calorie restriction and longevity
    • B.J. Merry Molecular mechanisms linking calorie restriction and longevity Int. J. Biochem. Cell Biol. 34 2002 1340 1354
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 1340-1354
    • Merry, B.J.1
  • 135
    • 3342891368 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial function with aging - The effects of calorie restriction
    • B.J. Merry Oxidative stress and mitochondrial function with aging - the effects of calorie restriction Aging Cell 3 2004 7 12
    • (2004) Aging Cell , vol.3 , pp. 7-12
    • Merry, B.J.1
  • 136
    • 0034888364 scopus 로고    scopus 로고
    • Heating stress patterns in Caenorhabditis elegans longevity and survivorship
    • A.I. Michalski, T.E. Johnson, J.R. Cypser, and A.I. Yashin Heating stress patterns in Caenorhabditis elegans longevity and survivorship Biogerontology 2 2001 35 44
    • (2001) Biogerontology , vol.2 , pp. 35-44
    • Michalski, A.I.1    Johnson, T.E.2    Cypser, J.R.3    Yashin, A.I.4
  • 138
    • 0036843071 scopus 로고    scopus 로고
    • Gene expression patterns in calorically restricted mice: Partial overlap with long-lived mutant mice
    • R.A. Miller, Y. Chang, A.T. Galecki, K. Al-Regaiey, J.J. Kopchick, and A. Bartke Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice Mol. Endocrinol. 16 2002 2657 2666
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2657-2666
    • Miller, R.A.1    Chang, Y.2    Galecki, A.T.3    Al-Regaiey, K.4    Kopchick, J.J.5    Bartke, A.6
  • 139
    • 0033026603 scopus 로고    scopus 로고
    • HSP70 induction may explain the long-lasting resistance to heat of Drosophila melanogaster having lived in hypergravity
    • N. Minois, M.J. Guinaudy, F. Payre, and E. Le Bourg HSP70 induction may explain the long-lasting resistance to heat of Drosophila melanogaster having lived in hypergravity Mech. Ageing Dev. 109 1999 65 77
    • (1999) Mech. Ageing Dev. , vol.109 , pp. 65-77
    • Minois, N.1    Guinaudy, M.J.2    Payre, F.3    Le Bourg, E.4
  • 140
    • 0037813163 scopus 로고    scopus 로고
    • Hypolipidemic action of dietary resveratrol, a phytoalexin in grapes and red wine, in hepatoma-bearing rats
    • D. Miura, Y. Miura, and K. Yagasaki Hypolipidemic action of dietary resveratrol, a phytoalexin in grapes and red wine, in hepatoma-bearing rats Life Sci. 73 2003 1393 1400
    • (2003) Life Sci. , vol.73 , pp. 1393-1400
    • Miura, D.1    Miura, Y.2    Yagasaki, K.3
  • 141
    • 3242737464 scopus 로고    scopus 로고
    • Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila
    • S. Miwa, K. Riyahi, L. Partridge, and M.D. Brand Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila Ann. N. Y. Acad. Sci. 1019 2004 388 391
    • (2004) Ann. N. Y. Acad. Sci. , vol.1019 , pp. 388-391
    • Miwa, S.1    Riyahi, K.2    Partridge, L.3    Brand, M.D.4
  • 143
    • 0035097846 scopus 로고    scopus 로고
    • Antioxidant status and stress resistance in long- and short-lived lines of Drosophila melanogaster
    • R.J. Mockett, W.C. Orr, J.J. Rahmandar, B.H. Sohal, and R.S. Sohal Antioxidant status and stress resistance in long- and short-lived lines of Drosophila melanogaster Exp. Gerontol. 36 2001 441 463
    • (2001) Exp. Gerontol. , vol.36 , pp. 441-463
    • Mockett, R.J.1    Orr, W.C.2    Rahmandar, J.J.3    Sohal, B.H.4    Sohal, R.S.5
  • 144
    • 0242384606 scopus 로고    scopus 로고
    • Selective alteration of DNA fragmentation and caspase activity in the spinal cord of aged rats and effect of dietary restriction.
    • B. Monti, and A. Contestabile Selective alteration of DNA fragmentation and caspase activity in the spinal cord of aged rats and effect of dietary restriction. Brain Res. 992 2003 137 141
    • (2003) Brain Res. , vol.992 , pp. 137-141
    • Monti, B.1    Contestabile, A.2
  • 146
    • 4143146391 scopus 로고    scopus 로고
    • Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors
    • P. Mukherjee, L.E. Abate, and T.N. Seyfried Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors Clin. Cancer Res. 10 2004 5622 5629
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5622-5629
    • Mukherjee, P.1    Abate, L.E.2    Seyfried, T.N.3
  • 147
    • 0042203536 scopus 로고    scopus 로고
    • Multiplex stress resistance in cells from long-lived dwarf mice
    • S. Murakami, A. Salmon, and R.A. Miller Multiplex stress resistance in cells from long-lived dwarf mice FASEB J. 17 2003 1565 1566
    • (2003) FASEB J. , vol.17 , pp. 1565-1566
    • Murakami, S.1    Salmon, A.2    Miller, R.A.3
  • 149
    • 0028874567 scopus 로고
    • Neuroendocrine involvement in aging: Evidence from studies of reproductive aging and caloric restriction
    • J.F. Nelson, K. Karelus, M.D. Bergman, and L.S. Felicio Neuroendocrine involvement in aging: evidence from studies of reproductive aging and caloric restriction Neurobiol. Aging 16 1995 837 843 discussion 855-856
    • (1995) Neurobiol. Aging , vol.16 , pp. 837-843
    • Nelson, J.F.1    Karelus, K.2    Bergman, M.D.3    Felicio, L.S.4
  • 150
    • 2942564591 scopus 로고    scopus 로고
    • Sirtuins: Sir2-related NAD-dependent protein deacetylases
    • B.J. North, and E. Verdin Sirtuins: Sir2-related NAD-dependent protein deacetylases Genome Biol. 5 2004 224
    • (2004) Genome Biol. , vol.5 , pp. 224
    • North, B.J.1    Verdin, E.2
  • 151
    • 0036929765 scopus 로고    scopus 로고
    • Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes
    • R. Pandey, A. Muller, C.A. Napoli, D.A. Selinger, C.S. Pikaard, E.J. Richards, J. Bender, D.W. Mount, and R.A. Jorgensen Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes Nucleic Acids Res. 30 2002 5036 5055
    • (2002) Nucleic Acids Res. , vol.30 , pp. 5036-5055
    • Pandey, R.1    Muller, A.2    Napoli, C.A.3    Selinger, D.A.4    Pikaard, C.S.5    Richards, E.J.6    Bender, J.7    Mount, D.W.8    Jorgensen, R.A.9
  • 154
    • 0242695672 scopus 로고    scopus 로고
    • Resveratrol: From grapevines to mammalian biology
    • S. Pervaiz Resveratrol: from grapevines to mammalian biology FASEB J. 17 2003 1975 1985
    • (2003) FASEB J. , vol.17 , pp. 1975-1985
    • Pervaiz, S.1
  • 156
    • 1242342067 scopus 로고    scopus 로고
    • Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: Relevance in cell proliferation
    • E. Pozo-Guisado, M.J. Lorenzo-Benayas, and P.M. Fernandez-Salguero Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation Int. J. Cancer 109 2004 167 173
    • (2004) Int. J. Cancer , vol.109 , pp. 167-173
    • Pozo-Guisado, E.1    Lorenzo-Benayas, M.J.2    Fernandez-Salguero, P.M.3
  • 157
    • 0032879458 scopus 로고    scopus 로고
    • Controlling caloric consumption: Protocols for rodents and rhesus monkeys
    • T.D. Pugh, R.G. Klopp, and R. Weindruch Controlling caloric consumption: protocols for rodents and rhesus monkeys Neurobiol. Aging 20 1999 157 165
    • (1999) Neurobiol. Aging , vol.20 , pp. 157-165
    • Pugh, T.D.1    Klopp, R.G.2    Weindruch, R.3
  • 159
    • 0031855258 scopus 로고    scopus 로고
    • Repeated mild heat shock delays ageing in cultured human skin fibroblasts
    • S.I. Rattan Repeated mild heat shock delays ageing in cultured human skin fibroblasts Biochem. Mol. Biol. Int. 45 1998 753 759
    • (1998) Biochem. Mol. Biol. Int. , vol.45 , pp. 753-759
    • Rattan, S.I.1
  • 160
    • 1842525838 scopus 로고    scopus 로고
    • Aging, anti-aging, and hormesis
    • S.I. Rattan Aging, anti-aging, and hormesis Mech. Ageing Dev. 125 2004 285 289
    • (2004) Mech. Ageing Dev. , vol.125 , pp. 285-289
    • Rattan, S.I.1
  • 161
    • 3843112334 scopus 로고    scopus 로고
    • Hormetic mechanisms of anti-aging and rejuvenating effects of repeated mild heat stress on human fibroblasts in vitro
    • S.I. Rattan Hormetic mechanisms of anti-aging and rejuvenating effects of repeated mild heat stress on human fibroblasts in vitro Rejuvenation Res. 7 2004 40 48
    • (2004) Rejuvenation Res. , vol.7 , pp. 40-48
    • Rattan, S.I.1
  • 162
  • 163
    • 10944270187 scopus 로고    scopus 로고
    • The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
    • J.R. Revollo, A.A. Grimm, and S. Imai The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells J. Biol. Chem. 279 2004 50754 50763
    • (2004) J. Biol. Chem. , vol.279 , pp. 50754-50763
    • Revollo, J.R.1    Grimm, A.A.2    Imai, S.3
  • 164
    • 8644224064 scopus 로고    scopus 로고
    • Sir2 mediates longevity in the fly through a pathway related to calorie restriction
    • B. Rogina, and S.L. Helfand Sir2 mediates longevity in the fly through a pathway related to calorie restriction Proc. Natl. Acad. Sci. U.S.A. 101 2004 15998 16003
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 15998-16003
    • Rogina, B.1    Helfand, S.L.2
  • 165
    • 0027382180 scopus 로고
    • Relationship between lipid peroxidation, fatty acid composition, and ascorbic acid in the liver during carbohydrate and caloric restriction in mice
    • C. Rojas, S. Cadenas, R. Perez-Campo, M. Lopez-Torres, R. Pamplona, J. Prat, and G. Barja Relationship between lipid peroxidation, fatty acid composition, and ascorbic acid in the liver during carbohydrate and caloric restriction in mice Arch. Biochem. Biophys. 306 1993 59 64
    • (1993) Arch. Biochem. Biophys. , vol.306 , pp. 59-64
    • Rojas, C.1    Cadenas, S.2    Perez-Campo, R.3    Lopez-Torres, M.4    Pamplona, R.5    Prat, J.6    Barja, G.7
  • 166
    • 0036856578 scopus 로고    scopus 로고
    • Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis
    • A. Rongvaux, R.J. Shea, M.H. Mulks, D. Gigot, J. Urbain, O. Leo, and F. Andris Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis Eur. J. Immunol. 32 2002 3225 3234
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3225-3234
    • Rongvaux, A.1    Shea, R.J.2    Mulks, M.H.3    Gigot, D.4    Urbain, J.5    Leo, O.6    Andris, F.7
  • 167
    • 0026684532 scopus 로고
    • Selection on stress resistance increases longevity in Drosophila melanogaster
    • M.R. Rose, L.N. Vu, S.U. Park, and J.L. Graves Jr. Selection on stress resistance increases longevity in Drosophila melanogaster Exp. Gerontol. 27 1992 241 250
    • (1992) Exp. Gerontol. , vol.27 , pp. 241-250
    • Rose, M.R.1    Vu, L.N.2    Park, S.U.3    Graves Jr., J.L.4
  • 169
    • 0027958452 scopus 로고
    • Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor
    • B. Samal, Y. Sun, G. Stearns, C. Xie, S. Suggs, and I. McNiece Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor Mol. Cell Biol. 14 1994 1431 1437
    • (1994) Mol. Cell Biol. , vol.14 , pp. 1431-1437
    • Samal, B.1    Sun, Y.2    Stearns, G.3    Xie, C.4    Suggs, S.5    McNiece, I.6
  • 170
    • 0038049827 scopus 로고    scopus 로고
    • Short-term caloric restriction and regulatory proteins of apoptosis in heart, skeletal muscle and kidney of Fischer 344 rats
    • C. Selman, R. Gredilla, S. Phaneuf, S. Kendaiah, G. Barja, and C. Leeuwenburgh Short-term caloric restriction and regulatory proteins of apoptosis in heart, skeletal muscle and kidney of Fischer 344 rats Biogerontology 4 2003 141 147
    • (2003) Biogerontology , vol.4 , pp. 141-147
    • Selman, C.1    Gredilla, R.2    Phaneuf, S.3    Kendaiah, S.4    Barja, G.5    Leeuwenburgh, C.6
  • 171
    • 0029117356 scopus 로고
    • Genotoxicity of tacrine in primary hepatocytes isolated from B6C3F1 mice and aged ad libitum and calorie restricted Fischer 344 rats
    • J.G. Shaddock, R.J. Feuers, M.W. Chou, D.H. Swenson, and D.A. Casciano Genotoxicity of tacrine in primary hepatocytes isolated from B6C3F1 mice and aged ad libitum and calorie restricted Fischer 344 rats Mutat. Res. 344 1995 79 88
    • (1995) Mutat. Res. , vol.344 , pp. 79-88
    • Shaddock, J.G.1    Feuers, R.J.2    Chou, M.W.3    Swenson, D.H.4    Casciano, D.A.5
  • 172
    • 0038297516 scopus 로고    scopus 로고
    • Inhibition of cell transformation by resveratrol and its derivatives: Differential effects and mechanisms involved
    • Q.B. She, W.Y. Ma, M. Wang, A. Kaji, C.T. Ho, and Z. Dong Inhibition of cell transformation by resveratrol and its derivatives: differential effects and mechanisms involved Oncogene 22 2003 2143 2150
    • (2003) Oncogene , vol.22 , pp. 2143-2150
    • She, Q.B.1    Ma, W.Y.2    Wang, M.3    Kaji, A.4    Ho, C.T.5    Dong, Z.6
  • 173
    • 0037362863 scopus 로고    scopus 로고
    • Lifelong caloric restriction increases expression of apoptosis repressor with a caspase recruitment domain (ARC) in the brain
    • R.R. Shelke, and C. Leeuwenburgh Lifelong caloric restriction increases expression of apoptosis repressor with a caspase recruitment domain (ARC) in the brain FASEB J. 17 2003 494 496
    • (2003) FASEB J. , vol.17 , pp. 494-496
    • Shelke, R.R.1    Leeuwenburgh, C.2
  • 174
    • 0032698165 scopus 로고    scopus 로고
    • Yeast aging research: Recent advances and medical relevance
    • D.A. Sinclair Yeast aging research: recent advances and medical relevance Cell Mol. Life Sci. 56 1999 807 816
    • (1999) Cell Mol. Life Sci. , vol.56 , pp. 807-816
    • Sinclair, D.A.1
  • 175
    • 0031459980 scopus 로고    scopus 로고
    • Extrachromosomal rDNA circles - A cause of aging in yeast
    • D.A. Sinclair, and L. Guarente Extrachromosomal rDNA circles - a cause of aging in yeast Cell 91 1997 1033 1042
    • (1997) Cell , vol.91 , pp. 1033-1042
    • Sinclair, D.A.1    Guarente, L.2
  • 176
    • 0000853087 scopus 로고
    • Prolongation of the life of Drosophila subobscura by a brief exposure of adults to a high temperature
    • J.M. Smith Prolongation of the life of Drosophila subobscura by a brief exposure of adults to a high temperature Nature 181 1958 496 497
    • (1958) Nature , vol.181 , pp. 496-497
    • Smith, J.M.1
  • 177
    • 0034756570 scopus 로고    scopus 로고
    • Larval crowding in Drosophila melanogaster induces Hsp70 expression, and leads to increased adult longevity and adult thermal stress resistance
    • J.G. Sorensen, and V. Loeschcke Larval crowding in Drosophila melanogaster induces Hsp70 expression, and leads to increased adult longevity and adult thermal stress resistance J. Insect Physiol. 47 2001 1301 1307
    • (2001) J. Insect Physiol. , vol.47 , pp. 1301-1307
    • Sorensen, J.G.1    Loeschcke, V.2
  • 178
    • 0000000661 scopus 로고
    • Effects of extract of western red-cedar heartwood on certain wood decaying fungi in culture
    • C.M. Southam, and J. Ehrlich Effects of extract of western red-cedar heartwood on certain wood decaying fungi in culture Phytopathology 33 1943 517 524
    • (1943) Phytopathology , vol.33 , pp. 517-524
    • Southam, C.M.1    Ehrlich, J.2
  • 180
    • 7044225238 scopus 로고    scopus 로고
    • Age-related changes in the metabolism and body composition of three dog breeds and their relationship to life expectancy
    • J.R. Speakman, A. van Acker, and E.J. Harper Age-related changes in the metabolism and body composition of three dog breeds and their relationship to life expectancy Aging Cell 2 2003 265 275
    • (2003) Aging Cell , vol.2 , pp. 265-275
    • Speakman, J.R.1    Van Acker, A.2    Harper, E.J.3
  • 181
    • 0042422245 scopus 로고    scopus 로고
    • Testing an 'aging gene' in long-lived Drosophila strains: Increased longevity depends on sex and genetic background
    • C.C. Spencer, C.E. Howell, A.R. Wright, and D.E. Promislow Testing an 'aging gene' in long-lived Drosophila strains: increased longevity depends on sex and genetic background Aging Cell 2 2003 123 130
    • (2003) Aging Cell , vol.2 , pp. 123-130
    • Spencer, C.C.1    Howell, C.E.2    Wright, A.R.3    Promislow, D.E.4
  • 183
    • 0025888306 scopus 로고
    • Aging and restriction of dietary calories increases insulin receptor mRNA, and aging increases glucocorticoid receptor mRNA in the liver of female C3B10RF1 mice
    • S.R. Spindler, J.M. Grizzle, R.L. Walford, and P.L. Mote Aging and restriction of dietary calories increases insulin receptor mRNA, and aging increases glucocorticoid receptor mRNA in the liver of female C3B10RF1 mice J. Gerontol. 46 1991 B233 B237
    • (1991) J. Gerontol. , vol.46
    • Spindler, S.R.1    Grizzle, J.M.2    Walford, R.L.3    Mote, P.L.4
  • 184
    • 0029164710 scopus 로고
    • Role of oxidized amino acids in protein breakdown and stability
    • E.R. Stadtman Role of oxidized amino acids in protein breakdown and stability Methods Enzymol. 258 1995 379 393
    • (1995) Methods Enzymol. , vol.258 , pp. 379-393
    • Stadtman, E.R.1
  • 185
    • 27244461732 scopus 로고    scopus 로고
    • Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation
    • S. Stojanovic, H. Sprinz, and O. Brede Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation Arch. Biochem. Biophys. 391 2001 79 89
    • (2001) Arch. Biochem. Biophys. , vol.391 , pp. 79-89
    • Stojanovic, S.1    Sprinz, H.2    Brede, O.3
  • 186
    • 0014095225 scopus 로고
    • Environmental factors in aging and mortality
    • B.L. Strehler Environmental factors in aging and mortality Environ. Res. 1 1967 46 88
    • (1967) Environ. Res. , vol.1 , pp. 46-88
    • Strehler, B.L.1
  • 187
    • 2442695594 scopus 로고    scopus 로고
    • Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction
    • J.A. Stuart, B. Karahalil, B.A. Hogue, N.C. Souza-Pinto, and V.A. Bohr Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction FASEB J. 18 2004 595 597
    • (2004) FASEB J. , vol.18 , pp. 595-597
    • Stuart, J.A.1    Karahalil, B.2    Hogue, B.A.3    Souza-Pinto, N.C.4    Bohr, V.A.5
  • 190
    • 0842283349 scopus 로고    scopus 로고
    • Aging increases DNase gamma, an apoptosis-related endonuclease, in rat liver nuclei: Effect of dietary restriction
    • K. Tanaka, Y. Higami, T. Tsuchiya, D. Shiokawa, S. Tanuma, H. Ayabe, and I. Shimokawa Aging increases DNase gamma, an apoptosis-related endonuclease, in rat liver nuclei: effect of dietary restriction Exp. Gerontol. 39 2004 195 202
    • (2004) Exp. Gerontol. , vol.39 , pp. 195-202
    • Tanaka, K.1    Higami, Y.2    Tsuchiya, T.3    Shiokawa, D.4    Tanuma, S.5    Ayabe, H.6    Shimokawa, I.7
  • 191
    • 0037470501 scopus 로고    scopus 로고
    • The endocrine regulation of aging by insulin-like signals
    • M. Tatar, A. Bartke, and A. Antebi The endocrine regulation of aging by insulin-like signals Science 299 2003 1346 1351
    • (2003) Science , vol.299 , pp. 1346-1351
    • Tatar, M.1    Bartke, A.2    Antebi, A.3
  • 192
    • 0036132431 scopus 로고    scopus 로고
    • Caloric restriction and lifespan: A role for protein turnover?
    • N. Tavernarakis, and M. Driscoll Caloric restriction and lifespan: a role for protein turnover? Mech. Ageing Dev. 123 2002 215 229
    • (2002) Mech. Ageing Dev. , vol.123 , pp. 215-229
    • Tavernarakis, N.1    Driscoll, M.2
  • 193
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • H.A. Tissenbaum, and L. Guarente Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 410 2001 227 230
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 196
    • 0031668348 scopus 로고    scopus 로고
    • Hormesis - Implications for risk assessment caloric intake (body weight) as an exemplar
    • A. Turturro, B. Hass, and R.W. Hart Hormesis - implications for risk assessment caloric intake (body weight) as an exemplar Hum. Exp. Toxicol. 17 1998 454 459
    • (1998) Hum. Exp. Toxicol. , vol.17 , pp. 454-459
    • Turturro, A.1    Hass, B.2    Hart, R.W.3
  • 197
  • 201
    • 0030033521 scopus 로고    scopus 로고
    • The beneficial effects of dietary restriction: Reduced oxidative damage and enhanced apoptosis
    • J.T. Wachsman The beneficial effects of dietary restriction: reduced oxidative damage and enhanced apoptosis Mutat. Res. 350 1996 25 34
    • (1996) Mutat. Res. , vol.350 , pp. 25-34
    • Wachsman, J.T.1
  • 202
    • 0041507039 scopus 로고    scopus 로고
    • Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals
    • G.A. Walker, and G.J. Lithgow Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals Aging Cell 2 2003 131 139
    • (2003) Aging Cell , vol.2 , pp. 131-139
    • Walker, G.A.1    Lithgow, G.J.2
  • 203
    • 0038718723 scopus 로고    scopus 로고
    • Intermittent fasting and dietary supplementation with 2-deoxy-d-glucose improve functional and metabolic cardiovascular risk factors in rats
    • R. Wan, S. Camandola, and M.P. Mattson Intermittent fasting and dietary supplementation with 2-deoxy-d-glucose improve functional and metabolic cardiovascular risk factors in rats FASEB J. 17 2003 1133 1134
    • (2003) FASEB J. , vol.17 , pp. 1133-1134
    • Wan, R.1    Camandola, S.2    Mattson, M.P.3
  • 204
    • 4143103524 scopus 로고    scopus 로고
    • Dietary supplementation with 2-deoxy-d-glucose improves cardiovascular and neuroendocrine stress adaptation in rats
    • R. Wan, S. Camandola, and M.P. Mattson Dietary supplementation with 2-deoxy-d-glucose improves cardiovascular and neuroendocrine stress adaptation in rats Am. J. Physiol. Heart Circ. Physiol. 287 2004 H1186 H1193
    • (2004) Am. J. Physiol. Heart Circ. Physiol. , vol.287
    • Wan, R.1    Camandola, S.2    Mattson, M.P.3
  • 205
    • 4344591769 scopus 로고    scopus 로고
    • Multiple-stress analysis for isolation of Drosophila longevity genes
    • H.D. Wang, P. Kazemi-Esfarjani, and S. Benzer Multiple-stress analysis for isolation of Drosophila longevity genes Proc. Natl. Acad. Sci. U.S.A. 101 2004 12610 12615
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 12610-12615
    • Wang, H.D.1    Kazemi-Esfarjani, P.2    Benzer, S.3
  • 206
    • 0035098360 scopus 로고    scopus 로고
    • Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice
    • R. Weindruch, T. Kayo, C.K. Lee, and T.A. Prolla Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice J. Nutr. 131 2001 918S 923S
    • (2001) J. Nutr. , vol.131
    • Weindruch, R.1    Kayo, T.2    Lee, C.K.3    Prolla, T.A.4
  • 209
    • 0000055057 scopus 로고
    • Pleiotropy, natural selection, and the evolution of senescence
    • G.C. Williams Pleiotropy, natural selection, and the evolution of senescence Evolution 11 1957 398 411
    • (1957) Evolution , vol.11 , pp. 398-411
    • Williams, G.C.1
  • 211
    • 0035885384 scopus 로고    scopus 로고
    • Ageing and survival after different doses of heat shock: The results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans
    • A.I. Yashin, J.R. Cypser, T.E. Johnson, A.I. Michalski, S.I. Boyko, and V.N. Novoseltsev Ageing and survival after different doses of heat shock: the results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans Mech. Ageing Dev. 122 2001 1477 1495
    • (2001) Mech. Ageing Dev. , vol.122 , pp. 1477-1495
    • Yashin, A.I.1    Cypser, J.R.2    Johnson, T.E.3    Michalski, A.I.4    Boyko, S.I.5    Novoseltsev, V.N.6
  • 212
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • F. Yeung, J.E. Hoberg, C.S. Ramsey, M.D. Keller, D.R. Jones, R.A. Frye, and M.W. Mayo Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase EMBO J. 23 2004 2369 2380
    • (2004) EMBO J. , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 213
    • 0022381249 scopus 로고
    • Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics
    • B.P. Yu, E.J. Masoro, and C.A. McMahan Nutritional influences on aging of Fischer 344 rats: I. Physical, metabolic, and longevity characteristics J. Gerontol. 40 1985 657 670
    • (1985) J. Gerontol. , vol.40 , pp. 657-670
    • Yu, B.P.1    Masoro, E.J.2    McMahan, C.A.3
  • 215


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.