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Volumn 52, Issue 2, 2006, Pages 316-326

Resveratrol-A boon for treating Alzheimer's disease?

Author keywords

Alzheimer's disease; Amyloid beta; Calorie restriction; Resveratrol; Sirtuins

Indexed keywords

HISTONE DEACETYLASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEASOME; REACTIVE OXYGEN METABOLITE; RESVERATROL; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN;

EID: 33747886389     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresrev.2006.04.004     Document Type: Review
Times cited : (323)

References (119)
  • 2
    • 0037437192 scopus 로고    scopus 로고
    • Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
    • Anandatheerthavarada H.K., Biswas G., Robin M.A., and Avadhani N.G. Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. J. Cell Biol. 161 (2003) 41-54
    • (2003) J. Cell Biol. , vol.161 , pp. 41-54
    • Anandatheerthavarada, H.K.1    Biswas, G.2    Robin, M.A.3    Avadhani, N.G.4
  • 3
    • 27844592673 scopus 로고    scopus 로고
    • Can plants provide a new generation of drugs for treating Alzheimer's disease?
    • Anekonda T.S., and Reddy P.H. Can plants provide a new generation of drugs for treating Alzheimer's disease?. Brain Res. Brain Res. Rev. 50 (2005) 361-376
    • (2005) Brain Res. Brain Res. Rev. , vol.50 , pp. 361-376
    • Anekonda, T.S.1    Reddy, P.H.2
  • 4
    • 33644875954 scopus 로고    scopus 로고
    • Neuronal protection by sirtuins in Alzheimer's disease
    • Anekonda T.S., and Reddy P.H. Neuronal protection by sirtuins in Alzheimer's disease. J. Neurochem. 96 (2006) 305-313
    • (2006) J. Neurochem. , vol.96 , pp. 305-313
    • Anekonda, T.S.1    Reddy, P.H.2
  • 5
    • 0034945280 scopus 로고    scopus 로고
    • Herbal medicines and perioperative care
    • Ang-Lee M.K., Moss J., and Yuan C.S. Herbal medicines and perioperative care. JAMA 286 (2001) 208-216
    • (2001) JAMA , vol.286 , pp. 208-216
    • Ang-Lee, M.K.1    Moss, J.2    Yuan, C.S.3
  • 6
    • 0035876087 scopus 로고    scopus 로고
    • Neuroprotective effects of lipoxygenase inhibitors against ischemic injury in rat hippocampal slice cultures
    • Arai K., Nishiyama N., Matsuki N., and Ikegaya Y. Neuroprotective effects of lipoxygenase inhibitors against ischemic injury in rat hippocampal slice cultures. Brain Res. Brain Res. Rev. 904 (2001) 167-172
    • (2001) Brain Res. Brain Res. Rev. , vol.904 , pp. 167-172
    • Arai, K.1    Nishiyama, N.2    Matsuki, N.3    Ikegaya, Y.4
  • 7
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • Araki T., Sasaki Y., and Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305 (2004) 1010-1013
    • (2004) Science , vol.305 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 8
    • 12944294341 scopus 로고    scopus 로고
    • Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK
    • Barthelemy C., Henderson C.E., and Pettmann B. Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK. BMC Neurosci. 5 (2004) 48
    • (2004) BMC Neurosci. , vol.5 , pp. 48
    • Barthelemy, C.1    Henderson, C.E.2    Pettmann, B.3
  • 9
    • 28244495389 scopus 로고    scopus 로고
    • Natural antioxidants and neurodegenerative diseases
    • Bastianetto S., and Quirion R. Natural antioxidants and neurodegenerative diseases. Front Biosci. 9 (2004) 3447-3452
    • (2004) Front Biosci. , vol.9 , pp. 3447-3452
    • Bastianetto, S.1    Quirion, R.2
  • 10
    • 0035235476 scopus 로고    scopus 로고
    • Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons
    • Bastianetto S., Zheng W.H., and Quirion R. Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons. Br. J. Pharmacol. 131 (2000) 711-720
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 711-720
    • Bastianetto, S.1    Zheng, W.H.2    Quirion, R.3
  • 11
    • 4243098426 scopus 로고    scopus 로고
    • Neuroscience. NAD to the rescue
    • (Erratum in: Science 308 (2005) 633)
    • Bedalov A., and Simon J.A. Neuroscience. NAD to the rescue. Science 305 (2004) 954-955 (Erratum in: Science 308 (2005) 633)
    • (2004) Science , vol.305 , pp. 954-955
    • Bedalov, A.1    Simon, J.A.2
  • 14
    • 3943054839 scopus 로고    scopus 로고
    • The Sir2 family of protein deacetylases
    • Blander G., and Guarente L. The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 73 (2004) 417-435
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 417-435
    • Blander, G.1    Guarente, L.2
  • 15
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • Bluher M., Kahn B.B., and Kahn C.R. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299 (2003) 572-574
    • (2003) Science , vol.299 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 16
    • 17144429302 scopus 로고    scopus 로고
    • Calorie restriction, SIRT1 and metabolism: understanding longevity
    • Bordone L., and Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat. Rev., Mol. Cell Biol. 6 (2005) 298-305
    • (2005) Nat. Rev., Mol. Cell Biol. , vol.6 , pp. 298-305
    • Bordone, L.1    Guarente, L.2
  • 17
    • 20444444649 scopus 로고    scopus 로고
    • Mechanism of human SIRT1 activation by resveratrol
    • Borra M.T., Smith B.C., and Denu J.M. Mechanism of human SIRT1 activation by resveratrol. J. Biol. Chem. 280 (2005) 17187-17195
    • (2005) J. Biol. Chem. , vol.280 , pp. 17187-17195
    • Borra, M.T.1    Smith, B.C.2    Denu, J.M.3
  • 19
    • 28844474597 scopus 로고    scopus 로고
    • SIRT1 protects against microglia-dependent beta amyloid toxicity through inhibiting NF-kappa B signaling
    • Chen J., Zhou Y., Mueller-Steiner S., Chen L.F., Kwon H., Yi S., Mucke L., and Gan L. SIRT1 protects against microglia-dependent beta amyloid toxicity through inhibiting NF-kappa B signaling. J. Biol. Chem. 280 (2005) 40364-40374
    • (2005) J. Biol. Chem. , vol.280 , pp. 40364-40374
    • Chen, J.1    Zhou, Y.2    Mueller-Steiner, S.3    Chen, L.F.4    Kwon, H.5    Yi, S.6    Mucke, L.7    Gan, L.8
  • 21
    • 20344407841 scopus 로고    scopus 로고
    • Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications
    • de la Lastra C.A., and Villegas L. Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications. Mol. Nutr. Food Res. 49 (2005) 405-430
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 405-430
    • de la Lastra, C.A.1    Villegas, L.2
  • 22
    • 15244350991 scopus 로고    scopus 로고
    • Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease
    • de la Monte S.M., and Wands J.R. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J. Alzheimer's Dis. 7 (2005) 45-61
    • (2005) J. Alzheimer's Dis. , vol.7 , pp. 45-61
    • de la Monte, S.M.1    Wands, J.R.2
  • 23
    • 0037221445 scopus 로고    scopus 로고
    • Linking chromatin function with metabolic networks: Sir2 family of NAD(C)-dependent deacetylases
    • Denu J.M. Linking chromatin function with metabolic networks: Sir2 family of NAD(C)-dependent deacetylases. Trends Biochem. Sci. 28 (2003) 41-48
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 41-48
    • Denu, J.M.1
  • 24
    • 9744222883 scopus 로고    scopus 로고
    • Protein quality control in Alzheimer's disease by the ubiquitin proteasome system
    • de Vrij F.M., Fischer D.F., van Leeuwen F.W., and Hol E.M. Protein quality control in Alzheimer's disease by the ubiquitin proteasome system. Prog. Neurobiol. 74 (2004) 249-270
    • (2004) Prog. Neurobiol. , vol.74 , pp. 249-270
    • de Vrij, F.M.1    Fischer, D.F.2    van Leeuwen, F.W.3    Hol, E.M.4
  • 25
    • 28244466940 scopus 로고    scopus 로고
    • Caloric restriction in humans: potential pitfalls and health concerns
    • Dirks A.J., and Leeuwenburgh C. Caloric restriction in humans: potential pitfalls and health concerns. Mech. Ageing Dev. 127 (2006) 1-7
    • (2006) Mech. Ageing Dev. , vol.127 , pp. 1-7
    • Dirks, A.J.1    Leeuwenburgh, C.2
  • 28
    • 12844282223 scopus 로고    scopus 로고
    • Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site
    • Flood F., Murphy S., Cowburn R.F., Lannfelt L., Walker B., and Johnston J.A. Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site. Biochem. J. 385 Pt 2 (2005) 545-550
    • (2005) Biochem. J. , vol.385 , Issue.PART 2 , pp. 545-550
    • Flood, F.1    Murphy, S.2    Cowburn, R.F.3    Lannfelt, L.4    Walker, B.5    Johnston, J.A.6
  • 29
    • 0033591299 scopus 로고    scopus 로고
    • Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids
    • Fremont L., Belguendouz L., and Delpal S. Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids. Life Sci. 64 (1999) 2511-2521
    • (1999) Life Sci. , vol.64 , pp. 2511-2521
    • Fremont, L.1    Belguendouz, L.2    Delpal, S.3
  • 30
    • 0033600176 scopus 로고    scopus 로고
    • Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
    • Frye R.A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 260 (1999) 273-279
    • (1999) Biochem. Biophys. Res. Commun. , vol.260 , pp. 273-279
    • Frye, R.A.1
  • 31
    • 0033887456 scopus 로고    scopus 로고
    • Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
    • Frye R.A. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem. Biophys. Res. Commun. 273 (2000) 793-798
    • (2000) Biochem. Biophys. Res. Commun. , vol.273 , pp. 793-798
    • Frye, R.A.1
  • 32
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: advances in eicosanoid biology
    • Funk C.D. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 294 (2001) 1871-1875
    • (2001) Science , vol.294 , pp. 1871-1875
    • Funk, C.D.1
  • 34
    • 24044472030 scopus 로고    scopus 로고
    • Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons
    • Gao Z.B., and Hu G.Y. Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons. Brain Res. 1056 (2005) 68-75
    • (2005) Brain Res. , vol.1056 , pp. 68-75
    • Gao, Z.B.1    Hu, G.Y.2
  • 36
    • 0042477712 scopus 로고    scopus 로고
    • FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
    • Gilley J., Coffer P.J., and Ham J. FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J. Cell Biol. 162 (2003) 613-622
    • (2003) J. Cell Biol. , vol.162 , pp. 613-622
    • Gilley, J.1    Coffer, P.J.2    Ham, J.3
  • 37
    • 0032608239 scopus 로고    scopus 로고
    • Billion-dollar market blossoms as botanicals take root
    • Glaser V. Billion-dollar market blossoms as botanicals take root. Nat. Biotechnol. 17 (1999) 17-18
    • (1999) Nat. Biotechnol. , vol.17 , pp. 17-18
    • Glaser, V.1
  • 38
    • 0035914304 scopus 로고    scopus 로고
    • Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening
    • Grozinger C.M., Chao E.D., Blackwell H.E., Moazed D., and Schreiber S.L. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. J. Biol. Chem. 276 (2001) 38837-38843
    • (2001) J. Biol. Chem. , vol.276 , pp. 38837-38843
    • Grozinger, C.M.1    Chao, E.D.2    Blackwell, H.E.3    Moazed, D.4    Schreiber, S.L.5
  • 39
    • 0034193776 scopus 로고    scopus 로고
    • Sir2 links chromatin silencing, metabolism, and aging
    • Guarente L. Sir2 links chromatin silencing, metabolism, and aging. Genes Dev. 14 (2000) 1021-1026
    • (2000) Genes Dev. , vol.14 , pp. 1021-1026
    • Guarente, L.1
  • 40
    • 24144494527 scopus 로고    scopus 로고
    • The physiology and pathophysiology of nitric oxide in the brain
    • Guix F.X., Uribesalgo I., Coma M., and Munoz F.J. The physiology and pathophysiology of nitric oxide in the brain. Prog. Neurobiol. 76 (2005) 126-152
    • (2005) Prog. Neurobiol. , vol.76 , pp. 126-152
    • Guix, F.X.1    Uribesalgo, I.2    Coma, M.3    Munoz, F.J.4
  • 41
    • 0037006035 scopus 로고    scopus 로고
    • Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats
    • Gupta Y.K., Briyal S., and Chaudhary S. Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats. Pharmacol. Biochem. Behav. 71 (2002) 245-249
    • (2002) Pharmacol. Biochem. Behav. , vol.71 , pp. 245-249
    • Gupta, Y.K.1    Briyal, S.2    Chaudhary, S.3
  • 42
    • 1942472491 scopus 로고    scopus 로고
    • Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C
    • Han Y.S., Zheng W.H., Bastianetto S., Chabot J.G., and Quirion R. Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C. Br. J. Pharmacol. 141 (2004) 997-1005
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 997-1005
    • Han, Y.S.1    Zheng, W.H.2    Bastianetto, S.3    Chabot, J.G.4    Quirion, R.5
  • 43
    • 27844548672 scopus 로고    scopus 로고
    • The proteasome in Alzheimer's disease and Parkinson's disease: lessons from ubiquitin B(+1)
    • Hol E.M., van Leeuwen F.W., and Fischer D.F. The proteasome in Alzheimer's disease and Parkinson's disease: lessons from ubiquitin B(+1). Trends Mol. Med. 11 (2005) 488-495
    • (2005) Trends Mol. Med. , vol.11 , pp. 488-495
    • Hol, E.M.1    van Leeuwen, F.W.2    Fischer, D.F.3
  • 44
    • 0043204252 scopus 로고    scopus 로고
    • Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function
    • Howes M.J., and Houghton P.J. Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function. Pharmacol. Biochem. Behav. 75 (2003) 513-527
    • (2003) Pharmacol. Biochem. Behav. , vol.75 , pp. 513-527
    • Howes, M.J.1    Houghton, P.J.2
  • 45
    • 0037272674 scopus 로고    scopus 로고
    • Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders
    • Howes M.J., Perry N.S., and Houghton P.J. Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders. Phytother. Res. 17 (2003) 1-18
    • (2003) Phytother. Res. , vol.17 , pp. 1-18
    • Howes, M.J.1    Perry, N.S.2    Houghton, P.J.3
  • 47
    • 0035919661 scopus 로고    scopus 로고
    • Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia
    • Huang S.S., Tsai M.C., Chih C.L., Hung L.M., and Tsai S.K. Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia. Life Sci. 69 (2001) 1057-1065
    • (2001) Life Sci. , vol.69 , pp. 1057-1065
    • Huang, S.S.1    Tsai, M.C.2    Chih, C.L.3    Hung, L.M.4    Tsai, S.K.5
  • 48
    • 0037446328 scopus 로고    scopus 로고
    • Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death
    • Jang J.H., and Surh Y.J. Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death. Free Radical Biol. Med. 34 (2003) 1100-1110
    • (2003) Free Radical Biol. Med. , vol.34 , pp. 1100-1110
    • Jang, J.H.1    Surh, Y.J.2
  • 50
    • 25644456097 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
    • Kitazawa M., Oddo S., Yamasaki T.R., Green K.N., and LaFerla F.M. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J. Neurosci. 25 (2005) 8843-8853
    • (2005) J. Neurosci. , vol.25 , pp. 8843-8853
    • Kitazawa, M.1    Oddo, S.2    Yamasaki, T.R.3    Green, K.N.4    LaFerla, F.M.5
  • 51
    • 0035065614 scopus 로고    scopus 로고
    • Bioavailability of dietary supplements and impact of physiologic state: infants, children and adolescents
    • (Apr.)
    • Krebs N.F. Bioavailability of dietary supplements and impact of physiologic state: infants, children and adolescents. J. Nutr. 31 Suppl. 4 (2001) 1351S-1354S (Apr.)
    • (2001) J. Nutr. , vol.31 , Issue.SUPPL. 4
    • Krebs, N.F.1
  • 54
    • 4344590155 scopus 로고    scopus 로고
    • Small molecules that regulate lifespan: evidence for xenohormesis
    • Lamming D.W., Wood J.G., and Sinclair D.A. Small molecules that regulate lifespan: evidence for xenohormesis. Mol. Microbiol. 53 (2004) 1003-1009
    • (2004) Mol. Microbiol. , vol.53 , pp. 1003-1009
    • Lamming, D.W.1    Wood, J.G.2    Sinclair, D.A.3
  • 57
    • 0030836586 scopus 로고    scopus 로고
    • Properties and regulation of cytosolic phospholipase A2
    • Leslie C.C. Properties and regulation of cytosolic phospholipase A2. J. Biol. Chem. 272 (1997) 16709-16712
    • (1997) J. Biol. Chem. , vol.272 , pp. 16709-16712
    • Leslie, C.C.1
  • 59
    • 27844497059 scopus 로고    scopus 로고
    • Resveratrol promotes clearance of Alzheimer's disease amyloid-{beta} peptides
    • Marambaud P., Zhao H., and Davies P. Resveratrol promotes clearance of Alzheimer's disease amyloid-{beta} peptides. J. Biol. Chem. 280 (2005) 37377-37382
    • (2005) J. Biol. Chem. , vol.280 , pp. 37377-37382
    • Marambaud, P.1    Zhao, H.2    Davies, P.3
  • 60
    • 0029610011 scopus 로고
    • The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases
    • McGeer P.L., and McGeer E.G. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res. Brain Res. Rev. 21 (1995) 195-218
    • (1995) Brain Res. Brain Res. Rev. , vol.21 , pp. 195-218
    • McGeer, P.L.1    McGeer, E.G.2
  • 61
    • 26244436281 scopus 로고    scopus 로고
    • Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
    • Michishita E., Park J.Y., Burneskis J.M., Barrett J.C., and Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Biol. Cell 16 (2005) 4623-4635
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4623-4635
    • Michishita, E.1    Park, J.Y.2    Burneskis, J.M.3    Barrett, J.C.4    Horikawa, I.5
  • 62
    • 0242268945 scopus 로고    scopus 로고
    • Immunotherapeutic approaches to Alzheimer's disease
    • Monsonego A., and Weiner H.L. Immunotherapeutic approaches to Alzheimer's disease. Science 302 (2003) 834-838
    • (2003) Science , vol.302 , pp. 834-838
    • Monsonego, A.1    Weiner, H.L.2
  • 63
    • 0036646172 scopus 로고    scopus 로고
    • Alternative therapies for traditional disease states: menopause
    • Morelli V., and Naquin C. Alternative therapies for traditional disease states: menopause. Am. Fam. Physician 66 (2002) 129-134
    • (2002) Am. Fam. Physician , vol.66 , pp. 129-134
    • Morelli, V.1    Naquin, C.2
  • 65
    • 0022711802 scopus 로고
    • Alcoholic beverages and coronary heart disease
    • Nanji A.A., and French S.W. Alcoholic beverages and coronary heart disease. Atherosclerosis 60 (1986) 197-198
    • (1986) Atherosclerosis , vol.60 , pp. 197-198
    • Nanji, A.A.1    French, S.W.2
  • 68
    • 2942564591 scopus 로고    scopus 로고
    • Sirtuins: Sir2-related NAD-dependent protein deacetylates
    • North B.J., and Verdin E. Sirtuins: Sir2-related NAD-dependent protein deacetylates. Genome Biol. 5 (2005) 224
    • (2005) Genome Biol. , vol.5 , pp. 224
    • North, B.J.1    Verdin, E.2
  • 69
    • 0037291214 scopus 로고    scopus 로고
    • The human Sir2 ortholog, SIRT2, is an NAD+ dependent tubulin deacetylase
    • North B.J., Marshall B.L., Borra M.T., Denu J.M., and Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+ dependent tubulin deacetylase. Mol. Cell 11 (2003) 437-444
    • (2003) Mol. Cell , vol.11 , pp. 437-444
    • North, B.J.1    Marshall, B.L.2    Borra, M.T.3    Denu, J.M.4    Verdin, E.5
  • 71
    • 4544300103 scopus 로고    scopus 로고
    • Inhibition of human liver and duodenum sulfotransferases by drugs and dietary chemicals: a review of the literature
    • Pacifici G.M. Inhibition of human liver and duodenum sulfotransferases by drugs and dietary chemicals: a review of the literature. Int. J. Clin. Pharmacol. Ther. 42 (2004) 488-495
    • (2004) Int. J. Clin. Pharmacol. Ther. , vol.42 , pp. 488-495
    • Pacifici, G.M.1
  • 73
    • 16844375290 scopus 로고    scopus 로고
    • Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons
    • (Erratum in: Nat Genet. 37, 555)
    • Parker J.A., Arango M., Abderrahmane S., Lambert E., Tourette C., Catoire H., and Neri C. Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons. Nat. Genet. 37 (2005) 349-350 (Erratum in: Nat Genet. 37, 555)
    • (2005) Nat. Genet. , vol.37 , pp. 349-350
    • Parker, J.A.1    Arango, M.2    Abderrahmane, S.3    Lambert, E.4    Tourette, C.5    Catoire, H.6    Neri, C.7
  • 74
    • 0242695672 scopus 로고    scopus 로고
    • Resveratrol: from grapevines to mammalian biology
    • Pervaiz S. Resveratrol: from grapevines to mammalian biology. FASEB J. 17 (2003) 1975-1985
    • (2003) FASEB J. , vol.17 , pp. 1975-1985
    • Pervaiz, S.1
  • 76
    • 12844271254 scopus 로고    scopus 로고
    • The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension
    • Porcu M., and Chiarugi A. The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension. Trends Pharmacol. Sci. 26 (2005) 94-103
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 94-103
    • Porcu, M.1    Chiarugi, A.2
  • 77
    • 7444250507 scopus 로고    scopus 로고
    • Degradation of BACE by the ubiquitin-proteasome pathway
    • Qing, Zhou W., Christensen M.A., Sun X., Tong Y., and Song W. Degradation of BACE by the ubiquitin-proteasome pathway. FASEB J. 18 (2004) 1571-1573
    • (2004) FASEB J. , vol.18 , pp. 1571-1573
    • Qing1    Zhou, W.2    Christensen, M.A.3    Sun, X.4    Tong, Y.5    Song, W.6
  • 78
    • 29844432266 scopus 로고    scopus 로고
    • Insulin, insulin-degrading enzyme and amyloid-b peptide in Alzheimer's disease: review and hypothesis
    • Qiu W.Q., and Folstein F.M. Insulin, insulin-degrading enzyme and amyloid-b peptide in Alzheimer's disease: review and hypothesis. Neurobiol. Aging 27 (2006) 190-198
    • (2006) Neurobiol. Aging , vol.27 , pp. 190-198
    • Qiu, W.Q.1    Folstein, F.M.2
  • 80
    • 2542502430 scopus 로고    scopus 로고
    • ApoE genotype accounts for the vast majority of AD risk and AD pathology
    • Raber J., Huang Y., and Ashford J.W. ApoE genotype accounts for the vast majority of AD risk and AD pathology. Neurobiol. Aging 25 (2004) 641-650
    • (2004) Neurobiol. Aging , vol.25 , pp. 641-650
    • Raber, J.1    Huang, Y.2    Ashford, J.W.3
  • 82
    • 27544484846 scopus 로고    scopus 로고
    • Are mitochondria critical in the pathogenesis of Alzheimer's disease?
    • Reddy P.H., and Beal M.F. Are mitochondria critical in the pathogenesis of Alzheimer's disease?. Brain Res. Brain Res. Rev. 49 (2005) 618-632
    • (2005) Brain Res. Brain Res. Rev. , vol.49 , pp. 618-632
    • Reddy, P.H.1    Beal, M.F.2
  • 84
    • 0037432493 scopus 로고    scopus 로고
    • Red wine micronutrients as protective agents in Alzheimer like induced insult
    • Russo A., Palumbo M., Aliano C., Lempereur L., Scoto G., and Renis M. Red wine micronutrients as protective agents in Alzheimer like induced insult. Life Sci. 72 (2003) 2369-2379
    • (2003) Life Sci. , vol.72 , pp. 2369-2379
    • Russo, A.1    Palumbo, M.2    Aliano, C.3    Lempereur, L.4    Scoto, G.5    Renis, M.6
  • 87
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: genes, proteins, and therapy
    • Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol. Rev. 81 (2001) 741-766
    • (2001) Physiol. Rev. , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 88
    • 7944233158 scopus 로고    scopus 로고
    • Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases
    • Selkoe D.J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat. Cell Biol. 6 (2004) 1054-1061
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1054-1061
    • Selkoe, D.J.1
  • 89
    • 11444252265 scopus 로고    scopus 로고
    • BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression
    • Senawong T., Peterson V.J., and Leid M. BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression. Arch. Biochem. Biophys. 434 (2005) 316-325
    • (2005) Arch. Biochem. Biophys. , vol.434 , pp. 316-325
    • Senawong, T.1    Peterson, V.J.2    Leid, M.3
  • 90
    • 0037063709 scopus 로고    scopus 로고
    • Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats
    • Sharma M., and Gupta Y.K. Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats. Life Sci. 71 (2002) 2489-2498
    • (2002) Life Sci. , vol.71 , pp. 2489-2498
    • Sharma, M.1    Gupta, Y.K.2
  • 91
    • 17144424946 scopus 로고    scopus 로고
    • SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
    • Shi T., Wang F., Stieren E., and Tong Q. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J. Biol. Chem. 280 (2005) 13560-13567
    • (2005) J. Biol. Chem. , vol.280 , pp. 13560-13567
    • Shi, T.1    Wang, F.2    Stieren, E.3    Tong, Q.4
  • 92
    • 22744450382 scopus 로고    scopus 로고
    • Toward a unified theory of caloric restriction and longevity regulation
    • Sinclair D.A. Toward a unified theory of caloric restriction and longevity regulation. Mech. Ageing Dev. 126 (2005) 987-1002
    • (2005) Mech. Ageing Dev. , vol.126 , pp. 987-1002
    • Sinclair, D.A.1
  • 93
    • 0037189154 scopus 로고    scopus 로고
    • Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats
    • Sinha K., Chaudhary G., and Gupta Y.K. Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats. Life Sci. 71 (2002) 655-665
    • (2002) Life Sci. , vol.71 , pp. 655-665
    • Sinha, K.1    Chaudhary, G.2    Gupta, Y.K.3
  • 95
    • 33747892287 scopus 로고    scopus 로고
    • Apoptosis is secondary to non-apoptotic axonal degeneration in neurons exposed to Abeta in distal axons
    • (Aug 22; [Electronic publication ahead of print])
    • Song M.S., Saavedra L., and de Chaves E.L. Apoptosis is secondary to non-apoptotic axonal degeneration in neurons exposed to Abeta in distal axons. Neurobiol. Aging (2005) (Aug 22; [Electronic publication ahead of print])
    • (2005) Neurobiol. Aging
    • Song, M.S.1    Saavedra, L.2    de Chaves, E.L.3
  • 99
    • 18044398037 scopus 로고    scopus 로고
    • Alzheimer's disease: channeling APP to non-amyloidogenic processing
    • Tang B.L. Alzheimer's disease: channeling APP to non-amyloidogenic processing. Biochem. Biophys. Res. Commun. 331 (2005) 358-375
    • (2005) Biochem. Biophys. Res. Commun. , vol.331 , pp. 358-375
    • Tang, B.L.1
  • 100
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective
    • Tanzi R.E., and Bertram L. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120 (2005) 545-555
    • (2005) Cell , vol.120 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 101
    • 17844394677 scopus 로고    scopus 로고
    • N-acteyl cysteine alleviates oxidative damage to central nervous system of ApoE-deficient mice following folate and vitamin E-deficiency
    • Tchantchou F., Graves M., Rogers E., Ortiz D., and Shea T.B. N-acteyl cysteine alleviates oxidative damage to central nervous system of ApoE-deficient mice following folate and vitamin E-deficiency. J. Alzheimers Dis. 7 (2005) 135-138
    • (2005) J. Alzheimers Dis. , vol.7 , pp. 135-138
    • Tchantchou, F.1    Graves, M.2    Rogers, E.3    Ortiz, D.4    Shea, T.B.5
  • 102
    • 0038734242 scopus 로고    scopus 로고
    • Herbs commonly used by women
    • Tesch B.J. Herbs commonly used by women. Am. J. Obstet. Gynecol. 188 (2003) S44-S55
    • (2003) Am. J. Obstet. Gynecol. , vol.188
    • Tesch, B.J.1
  • 103
    • 0035826271 scopus 로고    scopus 로고
    • Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    • Tissenbaum H.A., and Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410 (2001) 227-230
    • (2001) Nature , vol.410 , pp. 227-230
    • Tissenbaum, H.A.1    Guarente, L.2
  • 104
    • 0033993607 scopus 로고    scopus 로고
    • Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats
    • Virgili M., and Contestabile A. Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats. Neurosci. Lett. 281 (2000) 123-126
    • (2000) Neurosci. Lett. , vol.281 , pp. 123-126
    • Virgili, M.1    Contestabile, A.2
  • 106
  • 107
    • 14644405529 scopus 로고    scopus 로고
    • A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase
    • Wallerath T., Li H., Godtel-Ambrust U., Schwarz P.M., and Forstermann U. A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase. Nitric Oxide 12 (2005) 97-104
    • (2005) Nitric Oxide , vol.12 , pp. 97-104
    • Wallerath, T.1    Li, H.2    Godtel-Ambrust, U.3    Schwarz, P.M.4    Forstermann, U.5
  • 108
    • 14944378094 scopus 로고    scopus 로고
    • Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation
    • Walsh D.M., Townsend M., Podlisny M.B., Shankar G.M., Fadeeva J.V., Agnaf O.E., Hartley D.M., and Selkoe D.J. Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation. J. Neurosci. 25 (2005) 2455-2462
    • (2005) J. Neurosci. , vol.25 , pp. 2455-2462
    • Walsh, D.M.1    Townsend, M.2    Podlisny, M.B.3    Shankar, G.M.4    Fadeeva, J.V.5    Agnaf, O.E.6    Hartley, D.M.7    Selkoe, D.J.8
  • 109
    • 0035212387 scopus 로고    scopus 로고
    • Resveratrol inhibits interleukin-6 production in cortical mixed glial cells under hypoxia/hypoglycemia followed by reoxygenation
    • Wang M.J., Huang H.M., Hsieh S.J., Jeng K.C., and Kuo J.S. Resveratrol inhibits interleukin-6 production in cortical mixed glial cells under hypoxia/hypoglycemia followed by reoxygenation. J. Neuroimmunol. 112 (2001) 28-34
    • (2001) J. Neuroimmunol. , vol.112 , pp. 28-34
    • Wang, M.J.1    Huang, H.M.2    Hsieh, S.J.3    Jeng, K.C.4    Kuo, J.S.5
  • 110
  • 111
    • 20344364428 scopus 로고    scopus 로고
    • Metabolism and bioavailability of trans-resveratrol
    • Wenzel E., and Somoza V. Metabolism and bioavailability of trans-resveratrol. Mol. Nutr. Food Res. 49 (2005) 472-481
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 472-481
    • Wenzel, E.1    Somoza, V.2
  • 112
    • 20344371723 scopus 로고    scopus 로고
    • Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats
    • Wenzel E., Soldo T., Erbersdobler H., and Somoza V. Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats. Mol. Nutr. Food Res. 49 (2005) 482-494
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 482-494
    • Wenzel, E.1    Soldo, T.2    Erbersdobler, H.3    Somoza, V.4
  • 114
    • 13844271387 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans: II. Review of 93 intervention studies
    • Williamson G., and Manach C. Bioavailability and bioefficacy of polyphenols in humans: II. Review of 93 intervention studies. Am. J. Clin. Nutr. 81 suppl. 1 (2005) 243S-255S
    • (2005) Am. J. Clin. Nutr. , vol.81 , Issue.SUPPL. 1
    • Williamson, G.1    Manach, C.2
  • 115
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • (Erratum in: Nature 431, 107)
    • Wood J.G., Rogina B., Lavu S., Howitz K., Helfand S.L., Tatar M., and Sinclair D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430 (2004) 686-689 (Erratum in: Nature 431, 107)
    • (2004) Nature , vol.430 , pp. 686-689
    • Wood, J.G.1    Rogina, B.2    Lavu, S.3    Howitz, K.4    Helfand, S.L.5    Tatar, M.6    Sinclair, D.7
  • 116
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F., Hoberg J.E., Ramsey C.S., Keller M.D., Jones D.R., Frye R.A., and Mayo M.W. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23 (2004) 2369-2380
    • (2004) EMBO J. , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 117
    • 22844438667 scopus 로고    scopus 로고
    • Crosstalk between p53 and FOXO transcription factors
    • You H., and Mak T.W. Crosstalk between p53 and FOXO transcription factors. Cell Cycle 4 (2005) 37-38
    • (2005) Cell Cycle , vol.4 , pp. 37-38
    • You, H.1    Mak, T.W.2
  • 118
    • 0037713341 scopus 로고    scopus 로고
    • Potential mechanism by which resveratrol, a red wine constituent, protects neurons
    • (May; discussion 287-288)
    • Zhuang H., Kim Y.S., Koehler R.C., and Dore S. Potential mechanism by which resveratrol, a red wine constituent, protects neurons. Ann. N. Y. Acad. Sci. 993 (2003) 276-286 (May; discussion 287-288)
    • (2003) Ann. N. Y. Acad. Sci. , vol.993 , pp. 276-286
    • Zhuang, H.1    Kim, Y.S.2    Koehler, R.C.3    Dore, S.4
  • 119
    • 0037111102 scopus 로고    scopus 로고
    • Resveratrol-induced limitation of dysfunction of mitochondria isolated from rat brain in an anoxia-reoxygenation model
    • Zini R., Morin C., Bertelli A., Bertelli A.A., and Tillement J.P. Resveratrol-induced limitation of dysfunction of mitochondria isolated from rat brain in an anoxia-reoxygenation model. Life Sci. 71 (2002) 3091-3108
    • (2002) Life Sci. , vol.71 , pp. 3091-3108
    • Zini, R.1    Morin, C.2    Bertelli, A.3    Bertelli, A.A.4    Tillement, J.P.5


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