SIRT1 transgenic mice show phenotypes resembling calorie restriction

Aging Cell

Volumn 6, Issue 6, 2007, Pages 759-767

  Bordone, Laura ^a,c   Cohen, Dena ^a   Robinson, Ashley ^a   Motta, Maria Carla ^a   Van Veen, Ed ^a   Czopik, Agnieszka ^a   Steele, Andrew D ^a,b   Crowe, Hayley ^c   Marmor, Stephen ^c   Luo, Jianyuan ^d   Gu, Wei ^d   Guarente, Leonard ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^d Columbia University ^*  (United States)

Author keywords

Calorie restriction; SIRT1; Transgenic mice

Indexed keywords

ADIPOCYTOKINE; BETA ACTIN; CHOLESTEROL; COMPLEMENTARY DNA; GLUCOSE; INSULIN; SIRTUIN; SIRTUIN1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; GENE OVEREXPRESSION; GLUCOSE TOLERANCE; HEMIZYGOSITY; LONGEVITY; MALE; METABOLIC PARAMETERS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REPRODUCTION; TRANSGENE; TRANSGENIC MOUSE;

ADIPOKINES; ANIMALS; BLOOD GLUCOSE; CALORIC RESTRICTION; CHOLESTEROL; INSULIN; LONGEVITY; MICE; MICE, TRANSGENIC; PHENOTYPE; SIRTUINS; UP-REGULATION;

MUS; MUS MUSCULUS;

EID: 36248975293     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2007.00335.x     Document Type: Article

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